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Publications

2016

Conservation of the Nrf2-mediated gene regulation of proteasome subunits and glucose metabolism in zebrafish. Oxid Med Cell Longev in press.

Nguyen VT*, Fuse Y*, Tamaoki J, Akiyama S, Muratani M, Tamaru Y, Kobayashi M.  (*co-first)

Sensory systems and ionocytes are targets for silver nanoparticle effects in fish.Nanotoxicology 10:1276-1286.

Osborne OJ, Mukaigasa K, Nakajima H, Stolpe B, Romer I, Philips U, Lynch I, Mourabit S, Hirose S, Lead JR, Kobayashi M, Kudoh T, Tyler CR.

Nrf2-dependent protection against acute sodium arsenite toxicity in zebrafish. Toxicol Appl Pharmacol. 305:136-142.

Fuse Y, Nguyen VT, Kobayashi M,

    Evaluation of the toxicity and antioxidant activity of redox nanoparticles in zebrafish (Danio rerio) embryos.Mol Pharm 13:3091-3097.

    Vong LB, Kobayashi M, Nagasaki Y.


    2015

    PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination. Sci Adv 1:e1500615.

    Kim JD, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A.

    LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2. Proc Natl Acad Sci USA 112:13922-13927.

    Takeuchi M, Fuse Y, Watanabe M, Andrea CS, Takeuchi M, Nakajima H, Ohashi K, Kaneko H, Kobayashi-Osaki M, Yamamoto M, Kobayashi M.

    Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1. Genes Cells 20:590-600.

    Fuse Y*, Nakajima H*, Nakajima-Takagi Y, Nakajima O, Kobayashi M.  (*co-first)

    Lateralization, maturation, and anteroposterior topography in the lateral habenula revealed by ZIF268/EGR1 immunoreactivity and labeling history of neuronal activity. Neurosci Res 95:27-37.

    Ichijo H, Hamada M, Takahashi S, Kobayashi M, Nagai T, Toyama T, Kawaguchi M.


    2012

    Genetic evidence of an evolutionarily conserved role for Nrf2 in the protection against oxidative stress. Mol Cell Biol 32:4455-4461.

    Mukaigasa M*, Nguyen LTP*, Li L, Nakajima H, Yamamoto M, and Kobayashi M. (*co-first)


    2011

    Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse. Development 138:5357-5368.

    Ishitobi H, Wakamatsu A, Liu F, Azami T, Hamada M, Matsumoto K, Kataoka H, Kobayashi M, Choi K, Nishikawa SI, Takahashi S, Ema M.

    Tissue-restricted induction of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles. PLoS ONE 6:e26884. correction

    Nakajima H, Nakajima-Takagi Y, Tsujita T, Akiyama S, Wakasa T, Mukaigasa M, Kaneko H, Tamaru Y, Yamamoto M and Kobayashi M.

    Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. Genes Cells 16:46-57.

    Tsujita T*, Li L*, Nakajima H, Iwamoto N, Nakajima-Takagi Y, Ohashi K, Kawakami K, Kumagai Y, Yamamoto M, Kobayashi M.  (*co-first)


    2010

    Metalloprotease-dependent onset of blood circulation in zebrafish. Curr Biol 20:1110-1116.

    Iida A, Sakaguchi K, Sato K, Iwaki A, Takeuchi M, Kobayashi M, Misaki K, Yonemura S, Kawahara A, Sehara-Fujisawa A.

    Harnessing the antioxidant power with ARE-inducing compounds. Chem Biol 17:419-420.

    Kobayashi M.

    Efficient transient rescue of hematopoietic mutant phenotypes in zebrafish using Tol2-mediated transgenesis. Dev Growth Differ 52:245-250.

    Takeuchi M*, Kaneko H*, Nishikawa K, Kawakami K, Yamamoto M, Kobayashi M.  (*co-first)


    2009

    The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol Cell Biol 29:493-502.

    Kobayashi M, Li L, Iwamoto N, Nakajima-Takagi Y, Kaneko H, Nakayama Y, Eguchi M, Wada Y, Kumagai Y, Yamamoto M.

    The keratin-related Ouroboros proteins function as immune antigens mediating tail regression in Xenopus metamorphosis. Proc Natl Acad Sci USA 106:18309-18414.

    Mukaigasa K, Hanasaki A, Maeno M, Fujii H, Hayashida SI, Itoh M, Kobayashi M, Tochinai S, Hatta M, Iwabuchi K, Taira M, Onoe K, Izutsu Y.


    2008

    Molecular evolution of Keap1: Two Keap1 molecules with distinctive IVR structures are conserved among fish. J Biol Chem 283:3248-3255.

    Li L, Kobayashi M, Kaneko H, Nakajima-Takagi Y, Nakayama Y and Yamamoto M.


    2007

    Gata-1 self-association controls erythroid development in vivo. J Biol Chem 282:15862-15871. 

    Shimizu R, Trainor CD, Nishikawa K, Kobayashi M, Ohneda K and Yamamoto M.

    Regulation of GATA1 gene expression. J Biochem 142:1-10. 

    Kobayashi M and Yamamoto M.


    2006

    Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. Adv Enzyme Reg 46:113-140.

    Kobayashi M and Yamamoto M.


    2005

    Pi-class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish. Biochem J 388:65-73.

    Suzuki T, Takagi Y, Osanai H, Li L, Takeuchi M, Katoh Y, Kobayashi M and Yamamoto M.

    Lhx2 mediates the activity of Six3 in zebrafish forebrain growth. Dev Biol 287:456-468.

    Ando H, Kobayashi M, Tsubokawa T, Uyemura K, Furuta T and Okamoto H.

    Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 7:385-394. 

    Kobayashi M and Yamamoto M.


    2004

    MafT, a new member of the small Maf protein family in zebrafish. Biochem Biophys Res Commun 320:62-69. 

    Takagi Y, Kobayashi M, Li L, Suzuki T, Nishikawa K and Yamamoto M.

    Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for the vertebrate head specification. Development 131:57-71.

    Kimura-Yoshida C, Kitajima K, Oda-Ishii I, Tian E, Suzuki M, Yamamoto M, Suzuki T, Kobayashi M, Aizawa S and Matsuo I.

    A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish. Dev Cell 7:133-144.

    Kawakami K, Takeda H, Kawakami N, Kobayashi M, Matsuda N and Mishina M.


    2003

    Self-association of Gata1 enhances transcriptional activity in vivo in zebra fish embryos. Mol Cell Biol 23:8295-8305.

    Nishikawa K, Kobayashi M, Masumi A, Lyons SE, Weinstein BM, Liu PP and Yamamoto M.


    2002

    Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 7: 807-820.

    Kobayashi M, Itoh K, Suzuki T, Osanai H, Nishikawa K, Katoh Y, Takagi Y and Yamamoto M.

    Early subdivisions in the neural plate define distinct competence for inductive signals. Development 129:83-93. 

    Kobayashi D, Kobayashi M, Matsumoto K, Ogura T, Nakafuku M and Shimamura K.


    2001

    Hematopoietic regulatory domain of gata1 gene is positively regulated by GATA1 protein in zebrafish embryos. Development 128:2341-2350 

    Kobayashi M, Nishikawa K and Yamamoto M.

    The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation. Dev Biol 232:315-326.

    Kobayashi M, Nishikawa K, Suzuki T and Yamamoto M.

    Isolation, characterization, and expression analysis of zebrafish large Mafs. J Biochem 129:139-146. 

    Kajihara M, Kawauchi S, Kobayashi M, Ogino H, Takahashi S and Yasuda K.


    2000

    Expression of three zebrafish Six4 genes in the cranial sensory placodes and the developing somites. Mech Dev 98:151-155.

    Kobayashi M, Osanai H, Kawakami K and Yamamoto M.


    1999

    Structure and chromosomal mapping of the human SIX4 and murine Six4 genes. Cytogenet Cell Genet 87:108-112.

    Ozaki H, Yamada K, Kobayashi M, Asakawa S, Minoshima S, Shimizu N, Kajitani M and Kawakami K.

    Molecular recognition in gene transcription. Int J Med Biol Frontiers 7:9-20.

    Ishihama A, Zou C, Kobayashi M, Kumar A, Fujita N, Sakurai H and Hayward R.


    1998

    Overexpression of the forebrain-specific homeobox gene six3 induces rostral forebrain enlargement in zebrafish. Development 125:2973-2982. 

    Kobayashi M, Toyama R, Takeda H, Dawid IB and Kawakami K.

    Expression of LIM-domain binding protein (ldb) genes during zebrafish embryogenesis. Mech Dev 71:197-200. 

    Toyama R*, Kobayashi M*, Tomita T and Dawid IB.   (*co-first)

    Dominant negative ATF1 blocks cyclic AMP-induced neurite outgrowth in PC12D cells. J Neurochem 70:1029-1034.

    Shimomura A, Okamoto Y, Hirata Y, Kobayashi M, Kawakami K, Kiuchi K, Wakabayashi T and Hagiwara M.

    Tissue and developmental distribution of Six family gene products. Int J Dev Biol 42:141-148.

    Ohto H, Takizawa T, Saito T, Kobayashi M, Ikeda K and Kawakami K.