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Publications

2018

Ko S, Russell JO, Tian J, Gao C, Kobayashi M, Feng R, Yuan X, Shao C, Ding H, Poddar M, Singh S, Locker J, Weng H-L, Monga SP, Shin D: Hdac1 regulates differentiation of bipotent liver progenitor cells during regeneration via Sox9b and Cdk8. Gastroenterology on line.

Mukaigasa K*, Tsujita T*, Nguyen VT*, Li L*, Yagi H, Fuse Y, Nakajima-Takagi Y, Kato K, Yamamoto M, Kobayashi M (*co-first): Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish. Proc Natl Acad Sci USA 115:2758-2763.

Fuse Y, Endo Y, Araoi S. Daitoku H, Suzuki H, Kato M, Kobayashi M: The possible repositioning of an oral anti-arthritic drug, auranofin, for Nrf2-activating therapy: the demonstration of Nrf2-dependent anti-oxidative action using a zebrafish model. Free Rad Biol Med 115:405-411.

2017

Fuse Y, Kobayashi M. : Conservation of the Keap1-Nrf2 system: an evolutionary journey through stressful space and time. Molecules 22:436.

Tran MTN, Hamada M, Jeon H, Shiraishi R, Asano K, Hattori M, Nakamura M, Imamura Y, Tsunakawa Y, Fujii R, Usui T, Kulathunga K, Andrea CS, Koshida R, Kamei R, Matsunaga Y, Kobayashi M, Oishi H, Kudo T, Takahashi S: MafB is a critical regulator of complement component C1q. Nature Commun 8:1700.

2016

Nguyen VT*, Fuse Y*, Tamaoki J, Akiyama S, Muratani M, Tamaru Y, Kobayashi M. (*co-first): Conservation of the Nrf2-mediated gene regulation of proteasome subunits and glucose metabolism in zebrafish. Oxid Med Cell Longev 2016:5720574.

Fuse Y, Nguyen VT, Kobayashi M.: Nrf2-dependent protection against acute sodium arsenite toxicity in zebrafish. Toxicol Appl Pharmacol 305:136-142.

Osborne OJ, Mukaigasa K, Nakajima H, Stolpe B, Romer I, Philips U, Lynch I, Mourabit S, Hirose S, Lead JR, Kobayashi M, Kudoh T, Tyler CR.: Sensory systems and ionocytes are targets for silver nanoparticle effects in fish. Nanotoxicology 10:1276-1286.

Vong LB, Kobayashi M, Nagasaki Y.: Evaluation of the toxicity and antioxidant activity of redox nanoparticles in zebrafish (Danio rerio) embryos. Mol Pharm 13:3091-3097.

2015

Takeuchi M, Fuse Y, Watanabe M, Andrea CS, Takeuchi M, Nakajima H, Ohashi K, Kaneko H, Kobayashi-Osaki M, Yamamoto M, Kobayashi M.: LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2. Proc Natl Acad Sci USA 112:13922-13927.

Fuse Y*, Nakajima H*, Nakajima-Takagi Y, Nakajima O, Kobayashi M. (*co-first): Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1. Genes Cells 20:590-600.

Kim JD, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A.: PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination. Science Adv 1:e1500615.

Ichijo H, Hamada M, Takahashi S, Kobayashi M, Nagai T, Toyama T, Kawaguchi M.: Lateralization, maturation, and anteroposterior topography in the lateral habenula revealed by ZIF268/EGR1 immunoreactivity and labeling history of neuronal activity. Neurosci Res 95:27-37.

2012

Mukaigasa M, Nguyen LTP, Li L, Nakajima H, Yamamoto M, and Kobayashi M.: Genetic evidence of an evolutionarily conserved role for Nrf2 in the protection against oxidative stress. Mol Cell Biol 32:4455-4461.

2011

Nakajima H, Nakajima-Takagi Y, Tsujita T, Akiyama S, Wakasa T, Mukaigasa M, Kaneko H, Tamaru Y, Yamamoto M and Kobayashi M.: Tissue-restricted induction of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles. PLoS ONE 6:e26884. correction

Tsujita T*, Li L*, Nakajima H, Iwamoto N, Nakajima-Takagi Y, Ohashi K, Kawakami K, Kumagai Y, Yamamoto M, Kobayashi M. (*co-first): Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. Genes Cells 16:46-57.

Ishitobi H, Wakamatsu A, Liu F, Azami T, Hamada M, Matsumoto K, Kataoka H, Kobayashi M, Choi K, Nishikawa SI, Takahashi S, Ema M.: Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse. Development 138:5357-5368.

2010

Takeuchi M*, Kaneko H*, Nishikawa K, Kawakami K, Yamamoto M, Kobayashi M. (*co-first): Efficient transient rescue of hematopoietic mutant phenotypes in zebrafish using Tol2-mediated transgenesis. Dev Growth Differ 52:245-250.

Kobayashi M.: Harnessing the antioxidant power with ARE-inducing compounds. Chem Biol 17:419-420.

Iida A, Sakaguchi K, Sato K, Iwaki A, Takeuchi M, Kobayashi M, Misaki K, Yonemura S, Kawahara A, Sehara-Fujisawa A.: Metalloprotease-dependent onset of blood circulation in zebrafish. Curr Biol 20:1110-1116.

2009

Kobayashi M, Li L, Iwamoto N, Nakajima-Takagi Y, Kaneko H, Nakayama Y, Eguchi M, Wada Y, Kumagai Y, Yamamoto M.: The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol Cell Biol 29:493-502.

Mukaigasa K, Hanasaki A, Maeno M, Fujii H, Hayashida SI, Itoh M, Kobayashi M, Tochinai S, Hatta M, Iwabuchi K, Taira M, Onoe K, Izutsu Y.: The keratin-related Ouroboros proteins function as immune antigens mediating tail regression in Xenopus metamorphosis. Proc Natl Acad Sci USA 106:18309-18414.

2008

Li L, Kobayashi M, Kaneko H, Nakajima-Takagi Y, Nakayama Y, Yamamoto M.: Molecular evolution of Keap1: Two Keap1 molecules with distinctive IVR structures are conserved among fish. J Biol Chem 283:3248-3255.

2007

Shimizu R, Trainor CD, Nishikawa K, Kobayashi M, Ohneda K, Yamamoto M.: Gata-1 self-association controls erythroid development in vivo. J Biol Chem 282:15862-15871. 

Kobayashi M, Yamamoto M.: Regulation of GATA1 gene expression. J Biochem 142:1-10. 

2006

Kobayashi M, Yamamoto M.: Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. Adv Enzyme Reg 46:113-140.

2005

Suzuki T, Takagi Y, Osanai H, Li L, Takeuchi M, Katoh Y, Kobayashi M, Yamamoto M.: Pi-class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish. Biochem J 388:65-73.

Ando H, Kobayashi M, Tsubokawa T, Uyemura K, Furuta T, Okamoto H.: Lhx2 mediates the activity of Six3 in zebrafish forebrain growth. Dev Biol 287:456-468.

Kobayashi M, Yamamoto M.: Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 7:385-394. 

2004

Takagi Y, Kobayashi M, Li L, Suzuki T, Nishikawa K, Yamamoto M.: MafT, a new member of the small Maf protein family in zebrafish. Biochem Biophys Res Commun 320:62-69. 

Kimura-Yoshida C, Kitajima K, Oda-Ishii I, Tian E, Suzuki M, Yamamoto M, Suzuki T, Kobayashi M, Aizawa S, Matsuo I.: Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for the vertebrate head specification. Development 131:57-71.

Kawakami K, Takeda H, Kawakami N, Kobayashi M, Matsuda N, Mishina M.: A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish. Dev Cell 7:133-144.

2003

Nishikawa K, Kobayashi M, Masumi A, Lyons SE, Weinstein BM, Liu PP, Yamamoto M.: Self-association of Gata1 enhances transcriptional activity in vivo in zebra fish embryos. Mol Cell Biol 23:8295-8305.

2002

Kobayashi M, Itoh K, Suzuki T, Osanai H, Nishikawa K, Katoh Y, Takagi Y, Yamamoto M.: Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 7: 807-820.

Kobayashi D, Kobayashi M, Matsumoto K, Ogura T, Nakafuku M, Shimamura K.: Early subdivisions in the neural plate define distinct competence for inductive signals. Development 129:83-93. 

2001

Kobayashi M, Nishikawa K, Yamamoto M.: Hematopoietic regulatory domain of gata1 gene is positively regulated by GATA1 protein in zebrafish embryos. Development 128:2341-2350 

Kobayashi M, Nishikawa K, Suzuki T, Yamamoto M.: The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation. Dev Biol 232:315-326.

Kajihara M, Kawauchi S, Kobayashi M, Ogino H, Takahashi S, Yasuda K.: Isolation, characterization, and expression analysis of zebrafish large Mafs. J Biochem 129:139-146. 

2000

Kobayashi M, Osanai H, Kawakami K, Yamamoto M.: Expression of three zebrafish Six4 genes in the cranial sensory placodes and the developing somites. Mech Dev 98:151-155.

1999

Ozaki H, Yamada K, Kobayashi M, Asakawa S, Minoshima S, Shimizu N, Kajitani M, Kawakami K.: Structure and chromosomal mapping of the human SIX4 and murine Six4 genes. Cytogenet Cell Genet 87:108-112.

Ishihama A, Zou C, Kobayashi M, Kumar A, Fujita N, Sakurai H, Hayward R.: Molecular recognition in gene transcription. Int J Med Biol Frontiers 7:9-20.

1998

Kobayashi M, Toyama R, Takeda H, Dawid IB, Kawakami K.: Overexpression of the forebrain-specific homeobox gene six3 induces rostral forebrain enlargement in zebrafish. Development 125:2973-2982.
 

Toyama R*, Kobayashi M*, Tomita T, Dawid IB. (*co-first): Expression of LIM-domain binding protein (ldb) genes during zebrafish embryogenesis. Mech Dev 71:197-200.
 

Shimomura A, Okamoto Y, Hirata Y, Kobayashi M, Kawakami K, Kiuchi K, Wakabayashi T, Hagiwara M.: Dominant negative ATF1 blocks cyclic AMP-induced neurite outgrowth in PC12D cells. J Neurochem 70:1029-1034.

Ohto H, Takizawa T, Saito T, Kobayashi M, Ikeda K, Kawakami K.: Tissue and developmental distribution of Six family gene products. Int J Dev Biol 42:141-148.

1997

Kobayashi M, Shimomura A, Hagiwara M, Kawakami K.: Phosphorylation of ATF-1 enhances its DNA binding and transcription of the Na,K-ATPase a 1 subunit gene promoter. Nucleic Acids Res. 25: 877-882.

Kobayashi M, Kawakami K.: Synergism of the ATF/CRE site and GC box in the housekeeping Na,K-ATPase a 1 subunit gene is essential for constitutive expression. Biochem. Biophys. Res. Commun. 241: 169-174.

1996

Kobayashi M, Toyoda T, Ishihama A.: Influenza virus PB1 protein is the minimal and essential subunit of RNA polymerase. Arch. Virol. 141: 525-539.

Toyoda T, Adyshev DM, Kobayashi M, Iwata A, Ishihama A.: Molecular assembly of the influenza virus RNA polymerase: determination of the subunit-subunit contact sites. J. Gen. Virol. 77: 2149-2157.

Toyoda T, Kobayashi M, Nakada S, Ishihama A.: Molecular dissection of influenza virus RNA polymerase: PB1 subunit alone is able to catalyze RNA synthesis. Virus Genes 12: 155-163.

1995

Kobayashi M, Kawakami K.: ATF-1/CREB heterodimer is involved in constitutive expression of the housekeeping Na,K-ATPase a1subunit gene. Nucleic Acids Res., 23: 2848-2855.

1994

Kobayashi M, Toyoda T, Adyshev DM, Azuma Y, Ishihama A.: Molecular dissection of influenza virus nucleoprotein: deletion mapping of the RNA binding domain. J. Virol. 68: 8433-8436.

Toyoda T, Kobayashi M, Ishihama A.: Replication in vitro of the influenza virus genome: selective dissociation of RNA replicase from virus-infected cell ribonucleoprotein complexes. Arch. Virol. 136: 269-286.

1992

Kobayashi M, Tuchiya K, Nagata K, Ishihama A.: Reconstitution of influenza virus RNA polymerase from three subunits expressed using recombinant baculovirus system. Virus Res. 22(3): 235-245.

Seong BL, Kobayashi M, Nagata K, Brownlee GG, Ishihama A.: Comparison of two reconstitution systems for in vitro transcription and replication of influenza virus. J. Biochem. 111: 496-499.

1990

Kobayashi M, Nagata K, Ishihama A.: Promoter selectivity of Escherichia coli RNA polymerase: effect of base substitutions in the promoter -35 region on promoter strength. Nucleic Acids Res. 18: 7367-7372.

Hirai M, Kobayashi M, Shimizu N.: Reduced tyrosine phosphorylation and non-responsiveness to EGF-mediated cytotoxicity in EGF receptor hyperproducing UCVA-1 cells. Cell. Signal. 2: 245-252.

1989

Hirai M, Gamou S, Kobayashi M, Shimizu N.: Lung cancer cells often express high levels of Protein kinase C activity. Jpn. J. Cancer Res. 80: 204-208.