- Nishihara, S., Nakazato, M., Kudo, T., Kimura, H., Ando, T. and Narimatsu, H.: Human a-1,3 fucosyltransferase (FucT-VI) gene is located at only 13 kb 3' to the Lewis type fucosyltransferase (FucT-III) gene on chromosome 19. Biochem.Biophys.Res.Commun., 190: 42-46, 1993.
- Nishihara, S., Yazawa, S., Iwasaki, H., Nakazato, M., Kudo, T., Ando, T. and Narimatsu, H.: a (1,3/1,4)fucosyltransferase (FucT-III) gene is inactivated by a single amino acid substitution in Lewis histo-blood type negative individuals. Biochem.Biophys.Res.Commun., 196: 624-631, 1993.
- Kudo, T. and Narimatsu, H.: The b1,4-galactosyltransferase gene is post-transcriptionally regulated during differentiation of mouse F9 teratocarcinoma cells. Glycobiology, 5: 397-403, 1995.
- Kimura, H., Kudo, T., Nishihara, S., Iwasaki, H., Shinya, N., Watanabe, R., Honda, H., Takemura, F. and Narimatsu, H.: Murine monoclonal antibody recognizing human a(1,3/1,4)fucosyltransferase. Glycoconj.J., 12: 802-812, 1995.
- Narimatsu, H., Iwasaki, H., Nishihara, S., Kimura, H., Kudo, T., Yamauchi, Y. and Hirohashi, S.: Genetic evidence for the Lewis enzyme, which synthesizes type-1 Lewis antigens in colon tissue, and intracellular localization of the enzyme. Cancer Res., 56: 330-338, 1996.
- Kudo, T., Iwasaki, H., Nishihara, S., Shinya, N., Ando, T., Narimatsu, I. and Narimatsu, H.: Molecular genetic analysis of the human Lewis histo-blood group system. II. Secretor gene inactivation by a novel single missense mutation A385T in Japanese nonsecretor individuals. J.Biol.Chem., 271: 9830-9837, 1996.
- Kaneko, M., Nishihara, S., Shinya, N., Kudo, T., Iwasaki, H., Seno, T., Okubo, Y. and Narimatsu, H.: Wide variety of point mutations in the H gene of Bombay and para-Bombay individuals that inactivate H enzyme. Blood, 90: 839-849, 1997.
- Narimatsu, H., Iwasaki, H., Nakayama, F., Ikehara, Y., Kudo, T., Nishihara, S., Sugano, K., Okura, H., Fujita, S. and Hirohashi, S.: Lewis and secretor gene dosages affect CA19-9 and DU-PAN-2 serum levels in normal individuals and colorectal cancer patients. Cancer Res., 58: 512-518, 1998.
- Kudo, T., Ikehara, Y., Togayachi, A., Morozumi, K., Watanabe, M., Nakamura, M., Nishihara, S. and Narimatsu, H.: Up-regulation of a set of glycosyltransferase genes in human colorectal cancer. Lab. Invest., 78: 797-811, 1998.
- Kudo, T., Ikehara, Y., Togayachi, A., Kaneko, M., Hiraga, T., Sasaki, K. and Narimatsu, H.: Expression cloning and characterization of a novel murine a1, 3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney. J.Biol.Chem., 273: 26729-26738, 1998.
- Nakamura, M., Kudo, T., Narimatsu, H., Furukawa, Y., Kikuchi, J., Asakura, S., Yang, W., Iwase, S., Hatake, K. and Miura, Y.: Single glycosyltransferase, core 2 b1-->6-N-acetylglucosaminyltransferase, regulates cell surface sialyl-Lex expression level in human pre-B lymphocytic leukemia cell line KM3 treated with phorbolester. J.Biol.Chem., 273: 26779-26789, 1998.
- Ikehara, Y., Nishihara, S., Kudo, T., Hiraga, T., Morozumi, K., Hattori, T. and Narimatsu, H.: The aberrant expression of Lewis a antigen in intestinal metaplastic cells of gastric mucosa is caused by augmentation of Lewis enzyme expression. Glycoconj.J., 15: 799-807, 1998.
- Nakamura, M., Furukawa, Y., Sasaki, R., Masuyama, J., Kikuchi, J., Iwase, S., Kudo, T., Narimatsu, H., Asakura, S., Fujiwara, S. and Inokuchi, J.: UDP-GlcNAc:Galb1-->3GalNAc (GlcNAc to GalNAc) b1-->6N-acetylglucosaminyltransferase holds a key role on the control of CD15s expression in human pre-B lymphoid cell lines. Glycobiology, 9: 1-12, 1999.
- Nishihara, S., Hiraga, T., Ikehara, Y., Kudo, T., Iwasaki, H., Morozumi, K., Akamatsu, S., Tachikawa, T. and Narimatsu, H.: Molecular mechanisms of expression of Lewis b antigen and other type I Lewis antigens in human colorectal cancer. Glycobiology, 9: 607-616, 1999.
- Nishihara, S., Hiraga, T., Ikehara, Y., Iwasaki, H., Kudo, T., Yazawa, S., Morozumi, K., Suda, Y. and Narimatsu, H.: Molecular behavior of mutant Lewis enzymes in vivo. Glycobiology, 9: 373-382. 1999.
- Isshiki, S., Togayachi, A., Kudo, T., Nishihara, S., Watanabe, M., Kubota, T., Kitajima, M., Shiraishi, N., Sasaki, K., Andoh, T. and Narimatsu, H.: Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine b1,3-galactosyltransferase (b3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom. J.Biol.Chem., 274: 12499-12507, 1999.
- Kaneko, M., Kudo, T., Iwasaki, H., Ikehara, Y., Nishihara, S., Nakagawa, S., Sasaki, K., Shiina, T., Inoko, H., Saitou, N. and Narimatsu, H.: a1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX. FEBS Lett., 452: 237-242, 1999.
- Togayachi, A., Kudo, T., Ikehara, Y., Iwasaki, H., Nishihara, S., Andoh, T., Higashiyama, M., Kodama, K., Nakamori, S. and Narimatsu, H.: Up-regulation of Lewis enzyme (Fuc-TIII) and plasma-type a1,3fucosyltransferase (Fuc-TVI) expression determines the augmented expression of sialyl Lewis x antigen in non-small cell lung cancer. Int.J.Cancer, 83: 70-79, 1999.
- Yamada, Y., Itano, N., Narimatsu, H., Kudo, T., Hirohashi, S., Ochiai, A., Niimi, A., Ueda, M. and Kimata, K.: Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction. Jpn.J.Cancer Res., 90: 987-992, 1999.
- Kaneko, M., Kudo, T., Iwasaki, H., Shiina, T., Inoko, H., Kozaki, T., Saitou, N. and Narimatsu, H.: Assignment of the human a1,3-fucosyltransferase IX gene (FUT9) to chromosome band 6q16 by in situ hybridization. Cytogenet.Cell.Genet., 86: 329-330, 1999.
- Ikehara, Y., Kojima, N., Kurosawa, N., Kudo, T., Kono, M., Nishihara, S., Issiki, S., Morozumi, K., Itzkowitz, S., Tsuda, T., Nishimura, S.I., Tsuji, S. and Narimatsu, H.: Cloning and expression of a human gene encoding an N-acetylgalactosamine- a 2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens. Glycobiology, 9: 1213-1224, 1999.
- Nakayama, F., Teraki, Y., Kudo, T., Togayachi, A., Iwasaki, H., Tamatani, T., Nishihara, S., Mizukawa, Y., Shiohara, T. and Narimatsu, H.: Expression of cutaneous lymphocyte-associated antigen regulated by a set of glycosyltransferases in human T cells: involvement of a1, 3-fucosyltransferase VII and b1,4-galactosyltransferase I. J.Invest.Dermatol., 115: 299-306, 2000.
- Nakayama, F., Nishihara, S., Iwasaki, H., Kudo, T., Okubo, R., Kaneko, M., Nakamura, M., Karube, M., Sasaki, K. and Narimatsu, H.: CD15 expression in mature granulocytes is determined by a 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by a 1,3-fucosyltransferase IV. J.Biol.Chem, 276: 16100-16106, 2001.
- Togayachi, A., Akashima, T., Ookubo, R., Kudo, T., Nishihara, S., Iwasaki, H., Natsume, A., Mio, H., Inokuchi, J., Irimura, T., Sasaki, K. and Narimatsu, H.: Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide b1,3-N-acetylglucosaminyltransferase (b3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids. J.Biol.Chem., 276: 22032-22040, 2001.
- Shimoda, Y., Tajima, Y., Osanai, T., Katsume, A., Kohara, M., Kudo, T., Narimatsu, H., Takashima, N., Ishii, Y., Nakamura, S., Osumi, N. and Sanai, Y.: Pax6 controls the expression of Lewis x epitope in the embryonic forebrain by regulating a 1,3-fucosyltransferase IX expression. J.Biol.Chem., 277: 2033-2039, 2002.
- Iwai, T., Inaba, N., Naundorf, A., Zhang, Y., Gotoh, M., Iwasaki, H., Kudo, T., Togayachi, A., Ishizuka, Y., Nakanishi, H. and Narimatsu, H.: Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide b,3-N-acetylglucosaminyltransferase (b3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. J.Biol.Chem., 27: 12802-12809, 2002.
- Gotoh, M., Yada, T., Sato, T., Akashima, T., Iwasaki, H., Mochizuki, H., Inaba, N., Togayachi, A., Kudo, T., Watanabe, H., Kimata, K. and Narimatsu, H.: Molecular cloning and characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N-acetylgalactosamine. J.Biol.Chem., 277: 38179-38188, 2002.
- Gotoh, M., Sato, T., Akashima, T., Iwasaki, H., Kameyama, A., Mochizuki, H., Yada, T., Inaba, N., Zhang, Y., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Nishihara, S., Watanabe, H., Kimata, K. and Narimatsu, H.: Enzymatic synthesis of chondroitin with a novel chondroitin sulfate N-acetylgalactosaminyltransferase that transfers N-acetylgalactosamine to glucuronic acid in initiation and elongation of chondroitin sulfate synthesis. J.Biol.Chem., 277: 38189-38196, 2002.
- Kudo, T., Iwai, T., Kubota, T., Iwasaki, H., Takayama, Y., Hiruma, T., Inaba, N., Zhang, Y., Gotoh, M., Togayachi, A. and Narimatsu, H.: Molecular cloning and characterization of a novel UDP-Gal:GalNAc(a) peptide b1,3-galactosyltransferase (C1Gal-T2), an enzyme synthesizing a core 1 structure of O-glycan. J.Biol.Chem., 277: 47724-47731, 2002.
- Cheng, L., Tachibana, K., Zhang, Y., Guo, J., Kahori Tachibana, K., Kameyama, A., Wang, H., Hiruma, T., Iwasaki, H., Togayachi, A., Kudo, T. and Narimatsu, H.: Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10. FEBS Lett., 531: 115-121, 2002.
- Zhang, Y., Iwasaki, H., Wang, H., Kudo, T., Kalka, T.B., Hennet, T., Kubota, T., Cheng, L., Inaba, N., Gotoh, M., Togayachi, A., Guo, J., Hisatomi, H., Nakajima, K., Nishihara, S., Nakamura, M., Marth, J.D. and Narimatsu, H.: Cloning and characterization of a new human UDP-N-acetyl-a-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen. J.Biol.Chem., 278: 573-584, 2003.
- Iwasaki, H., Zhang, Y., Tachibana, K., Gotoh, M., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Kubota, T. and Narimatsu, H.: Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-a-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2. J.Biol.Chem., 278: 5613-5621, 2003.
- Sato, T., Gotoh, M., Kiyohara, K., Akashima, T., Iwasaki, H., Kameyama, A., Mochizuki, H., Yada, T., Inaba, N., Togayachi, A., Kudo, T., Asada, M., Watanabe, H., Imamura, T., Kimata, K. and Narimatsu, H.: Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate. J.Biol.Chem., 278: 3063-3071, 2003.
- Inaba, N., Hiruma, T., Togayachi, A., Iwasaki, H., Wang, X.H., Furukawa, Y., Sumi, R., Kudo, T., Fujimura, K., Iwai, T., Gotoh, M., Nakamura, M. and Narimatsu, H.: A novel I-branching b -1,6-N-acetylglucosaminyltransferase involved in human blood group I antigen expression. Blood, 101: 2870-2876, 2003.
- Wang, H., Tachibana, K., Zhang, Y., Iwasaki, H., Kameyama, A., Cheng, L., Guo, J., Hiruma, T., Togayachi, A., Kudo, T., Kikuchi, N. and Narimatsu, H.: Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14. Biochem.Biophys.Res.Commun., 300: 738-744, 2003.
- Nishihara, S., Iwasaki, H., Nakajima, K., Togayachi, A., Ikehara, Y., Kudo, T., Kushi, Y., Furuya, A., Shitara, K. and Narimatsu, H.: a1,3-fucosyltransferase IX (Fut9) determines Lewis X expression in brain. Glycobiology, 13: 445-455, 2003.
- Yada, T., Gotoh, M., Sato, T., Shionyu, M., Go, M., Kaseyama, H., Iwasaki, H., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Watanabe, H., Narimatsu, H. and Kimata, K.: Chondroitin Sulfate Synthase - 2 : Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities. J.Biol.Chem., 278: 30235-30247, 2003.
- Isshiki, S., Kudo, T., Nishihara, S., Ikehara, Y., Togayachi, A., Furuya, A., Shitara, K., Kubota, T., Watanabe, M., Kitajima, M. and Narimatsu, H.: Lewis type 1 antigen synthase (b3Gal-T5) is transcriptionally regulated by homeoproteins. J.Biol.Chem., 278: 36611-36620, 2003.
- Yada, T., Sato, T., Kaseyama, H., Gotoh, M., Iwasaki, H., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Watanabe, H., Narimatsu, H., Kimata, K.: Chondroitin sulfate synthase-3: Molecular cloning and characterization. J. Biol. Chem. 278: 39711-39725, 2003.
- Sato, T., Gotoh, M., Kiyohara, K., Kameyama, A., Kubota, T., Kikuchi, N., Ishizuka, Y., Iwasaki, H., Togayachi, A., Kudo, T., Ohkura, T., Nakanishi, H., Narimatsu, H.: Molecular cloning and characterization of a novel human b1,4-N-acetylgalactosaminyltransferase, b4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, GalNAc b1-4GlcNAc. J Biol Chem. 2003
- Yamada, Y., Itano, N., Narimatsu, H., Kudo, T., Hirohashi, S., Ochiai, A., Tohnai, I., Ueda, M., Kimata, K.: CD44 variant exon 6 expressions in colon cancer assessed by quantitative analysis using real time reverse transcriptase-polymerase chain reaction. Oncol Rep. 10:1919-1924, 2003.
- Yamada, Y., Itano, N., Narimatsu, H, Kudo, T., Morozumi, K., Hirohashi, S., Ochiai, A., Ueda, M., Kimata, K.:Elevated transcript level of hyaluronan synthase1 gene correlates with poor prognosis of human colon cancer. Clin Exp Metastasis. 2004;21(1):57-63.
- Kudo ,T, Kaneko ,M., Iwasaki, H., Togayachi, A., Nishihara, S., Abe, K., Narimatsu, H. :Normal Embryonic and Germ Cell Development in Mice Lacking alpha1,3-Fucosyltransferase IX (Fut9) Which Show Disappearance of Stage-Specific Embryonic Antigen 1. Mol Cell Biol. 2004 May 15;24(10):4221-4228.
- Cheng, L., Tachibana, K., Iwasaki, H., Kameyama, A., Zhang, Y., Kubota, T., Hiruma, T., Tachibana, K., Kudo, T., Guo, JM., Narimatsu, H. :Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T15.FEBS Lett. May 21;566(1-3):17-24,2004.
- Ishida H, Togayachi A, Sakai T, Iwai T, Hiruma T, Sato T, Okubo R, Inaba N, Kudo T, Gotoh M, Shoda J, Tanaka N, Narimatsu H.
A novel beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer.FEBS Lett. 2005 Jan 3;579(1):71-78.
- Iwai T, Kudo T, Kawamoto R, Kubota T, Togayachi A, Hiruma T, Okada T, Kawamoto T, Morozumi K, Narimatsu H.
Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells.
Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4572-4577.
- Zhang C, Moriguchi T, Kajihara M, Esaki R, Harada A, Shimohata H, Oishi H, Hamada M, Morito N, Hasegawa K, Kudo T, Engel JD, Yamamoto M, Takahashi S. MafA is a key regulator of glucose-stimulated insulin secretion.
Mol Cell Biol. 2005 Jun;25(12):4969-4976.
- Comelli EM, Head SR, Gilmartin T, Whisenant T, Haslam SM, North SJ, Wong NK, Kudo T, Narimatsu H, Esko JD, Drickamer K, Dell A, Paulson JC. A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology. 16,117-131,2006.
- Shimohata H, Yoh K, Morito N, Shimano H, Kudo T, Takahashi S.MafK overexpression in pancreatic beta-cells caused impairment of glucose-stimulated insulin secretion.Biochem Biophys Res Commun. 346,671-80. 2006.
- Moriguchi T, Hamada M, Morito N, Terunuma T, Hasegawa K, Zhang C, Yokomizo T, Esaki R, Kuroda E, Yoh K, Kudo T, Nagata M, Engel JD, Yamamoto M, Takahashi S. MafB is essential for renal development and F4/80 expression in macrophage. Mol Cell Biol. 26, 5715-5727, 2006.
- Kudo T, Fujii T, Ikegami S, Inokuchi K, Takayama Y, Ikehara Y, Nishihara S, Togayachi A, Takahashi S, Tachibana K, Yuasa S, Narimatsu H. Mice lacking alpha1,3-fucosyltransferase IX demonstrate disappearance of Lewis x structure in brain and increased anxiety-like behaviors.Glycobiology. 17, 1-9, 2007.
- Matsumura H, Kudo K, Harada A, Esaki R, Suzuki H, Kato M, Takahashi S. Suppression of MafA dependent transcription by transforming growth factor-β signaling. Biochem Biophys Res Commun . 364, 151-156, 2007
- Tanimoto Y, Iijima S, Suzuki Y, Daitoku Y, Hasegawa Y, Mizuno S, Ishige T, Kudo T, Takahashi S, Kunita S, Sugiyama F, Yagami K-i. Embryonic stem cells derived from C57BL/6J and C57BL/6N. Comparative Medicine. 58, 347-352, 2008.
- Takeuchi T, Kudo T, Ogata K, Hamada M, Nakamura M, Kito K, Abe Y, Ueda N, Yamamoto M, Engel JD, Takahashi S. Neither MafA/L-Maf nor MafB is essential for lens development in mice. Genes Cells. 14: 941-947, 2009.
- Nakamura M, Hamada M, Hasegawa K, Kusakabe M, Suzuki H, Greaves DR, Moriguchi T, Kudo T, Takahashi S. c-Maf is essential for the F4/80 expression in macrophages in vivo. Gene. 445: 66-72, 2009.
- Shimohata H, Yoh K, Fujita A, Morito N, Hirayama K, Kobayashi M, Kudo T, Yamagata K. Takahashi S. MafA-deficient and beta cell-specific MafK-overexpressing hybrid transgenic mice develop humen-like severe diabetic nephropathy. Biochem Biophys Res Commun. 389: 235-240, 2009.
- Togayachi A, Kozono Y, Ikehara Y, Ito H, Suzuki N, Tsunoda Y, Abe S,Sato T, Nakamura K, Suzuki M, Goda H, Ito M, Kudo T, Takahashi S, Narimatsu H. Lack of lacto/neolacto-glycolipids enhances the formation of glycolipid-enriched microdomains, facilitating B cell activation. Proc Natl Acad Sci USA. 107: 11900-11905, 2010.
-
Noso S, Kataoka K, Kawabata Y, Babaya N, Hiromine Y, Yamaji K, Fujisawa T, Aramata S, Kudo T, Takahashi S, Ikegami H. Insulin transactivator MafA regulates intra-thymic expression of insulin and affects susceptibility to type 1 diabetes. Diabetes, 59: 2579-2587, 2010.
- Morito N, Yoh K, Maeda A, Nakano T, Fujita A , Kusakabe M, Hamada M, Kudo T, Yamagata K, Takahashi S. A novel transgenic mouse model of the human multiple myeloma chromosomal translocation t(14;16)(q32;q23). Cancer Res, 71: 339-348, 2011.
- Sato T, Kudo T, Ikehara Y, Ogawa H, Hirano T, Kiyohara K, Hagiwara K, Togayachi A, Ema M, Takahashi S, Kimata K, Watanabe H, Narimatsu H. Chondroitin sulfate N-acetylgalactosaminyltransferase 1 deficient mice displays dwarfism with epiphyseal plate abnormalities. J Biol Chem, 286: 5803-5812, 2011.
- Kusakabe M, Hasegawa K, Hamada M, Nakamura M, Ohsumi T, Suzuki H, Tran TNM, Kudo T, Uchida K, Ninomiya H, Chiba S, Takahashi S. c-Maf plays a crucial role for the definitive erythropoiesis that accompanies erythroblastic island formation in the fetal liver. Blood, 118, 1374-1385, 2011.
- Sekiguchi Y, Owada J, Oishi H, Katsumata T, Ikeda K, Kudo T, Takahashi S. Non-invasive monitoring of beta-cell mass and fetal beta-cell genesis in mice using bioluminescence imaging. Exp.Anim., 61, 445-451, 2012.
- Katsumata T, Oishi H, Sekiguchi Y, Nagasaki H, Daasi D, Ema M, Kudo T, Takahashi S. Bioluminescence imaging of beta-cells and intrahepatic insulin gene activity under normal and pathological conditions. PLOS ONE, 8, e60411, 2013.
|