研究業績 工藤 崇  

英文 和文 著者


(英文)

  1. Nishihara, S., Nakazato, M., Kudo, T., Kimura, H., Ando, T. and Narimatsu, H.: Human a-1,3 fucosyltransferase (FucT-VI) gene is located at only 13 kb 3' to the Lewis type fucosyltransferase (FucT-III) gene on chromosome 19. Biochem.Biophys.Res.Commun., 190: 42-46, 1993.

  2. Nishihara, S., Yazawa, S., Iwasaki, H., Nakazato, M., Kudo, T., Ando, T. and Narimatsu, H.: a (1,3/1,4)fucosyltransferase (FucT-III) gene is inactivated by a single amino acid substitution in Lewis histo-blood type negative individuals. Biochem.Biophys.Res.Commun., 196: 624-631, 1993.

  3. Kudo, T. and Narimatsu, H.: The b1,4-galactosyltransferase gene is post-transcriptionally regulated during differentiation of mouse F9 teratocarcinoma cells. Glycobiology, 5: 397-403, 1995.

  4. Kimura, H., Kudo, T., Nishihara, S., Iwasaki, H., Shinya, N., Watanabe, R., Honda, H., Takemura, F. and Narimatsu, H.: Murine monoclonal antibody recognizing human a(1,3/1,4)fucosyltransferase. Glycoconj.J., 12: 802-812, 1995.

  5. Narimatsu, H., Iwasaki, H., Nishihara, S., Kimura, H., Kudo, T., Yamauchi, Y. and Hirohashi, S.: Genetic evidence for the Lewis enzyme, which synthesizes type-1 Lewis antigens in colon tissue, and intracellular localization of the enzyme. Cancer Res., 56: 330-338, 1996.

  6. Kudo, T., Iwasaki, H., Nishihara, S., Shinya, N., Ando, T., Narimatsu, I. and Narimatsu, H.: Molecular genetic analysis of the human Lewis histo-blood group system. II. Secretor gene inactivation by a novel single missense mutation A385T in Japanese nonsecretor individuals. J.Biol.Chem., 271: 9830-9837, 1996.

  7. Kaneko, M., Nishihara, S., Shinya, N., Kudo, T., Iwasaki, H., Seno, T., Okubo, Y. and Narimatsu, H.: Wide variety of point mutations in the H gene of Bombay and para-Bombay individuals that inactivate H enzyme. Blood, 90: 839-849, 1997.

  8. Narimatsu, H., Iwasaki, H., Nakayama, F., Ikehara, Y., Kudo, T., Nishihara, S., Sugano, K., Okura, H., Fujita, S. and Hirohashi, S.: Lewis and secretor gene dosages affect CA19-9 and DU-PAN-2 serum levels in normal individuals and colorectal cancer patients. Cancer Res., 58: 512-518, 1998.

  9. Kudo, T., Ikehara, Y., Togayachi, A., Morozumi, K., Watanabe, M., Nakamura, M., Nishihara, S. and Narimatsu, H.: Up-regulation of a set of glycosyltransferase genes in human colorectal cancer. Lab. Invest., 78: 797-811, 1998.

  10. Kudo, T., Ikehara, Y., Togayachi, A., Kaneko, M., Hiraga, T., Sasaki, K. and Narimatsu, H.: Expression cloning and characterization of a novel murine a1, 3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney. J.Biol.Chem., 273: 26729-26738, 1998.

  11. Nakamura, M., Kudo, T., Narimatsu, H., Furukawa, Y., Kikuchi, J., Asakura, S., Yang, W., Iwase, S., Hatake, K. and Miura, Y.: Single glycosyltransferase, core 2 b1-->6-N-acetylglucosaminyltransferase, regulates cell surface sialyl-Lex expression level in human pre-B lymphocytic leukemia cell line KM3 treated with phorbolester. J.Biol.Chem., 273: 26779-26789, 1998.

  12. Ikehara, Y., Nishihara, S., Kudo, T., Hiraga, T., Morozumi, K., Hattori, T. and Narimatsu, H.: The aberrant expression of Lewis a antigen in intestinal metaplastic cells of gastric mucosa is caused by augmentation of Lewis enzyme expression. Glycoconj.J., 15: 799-807, 1998.

  13. Nakamura, M., Furukawa, Y., Sasaki, R., Masuyama, J., Kikuchi, J., Iwase, S., Kudo, T., Narimatsu, H., Asakura, S., Fujiwara, S. and Inokuchi, J.: UDP-GlcNAc:Galb1-->3GalNAc (GlcNAc to GalNAc) b1-->6N-acetylglucosaminyltransferase holds a key role on the control of CD15s expression in human pre-B lymphoid cell lines. Glycobiology, 9: 1-12, 1999.

  14. Nishihara, S., Hiraga, T., Ikehara, Y., Kudo, T., Iwasaki, H., Morozumi, K., Akamatsu, S., Tachikawa, T. and Narimatsu, H.: Molecular mechanisms of expression of Lewis b antigen and other type I Lewis antigens in human colorectal cancer. Glycobiology, 9: 607-616, 1999.

  15. Nishihara, S., Hiraga, T., Ikehara, Y., Iwasaki, H., Kudo, T., Yazawa, S., Morozumi, K., Suda, Y. and Narimatsu, H.: Molecular behavior of mutant Lewis enzymes in vivo. Glycobiology, 9: 373-382. 1999.

  16. Isshiki, S., Togayachi, A., Kudo, T., Nishihara, S., Watanabe, M., Kubota, T., Kitajima, M., Shiraishi, N., Sasaki, K., Andoh, T. and Narimatsu, H.: Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine b1,3-galactosyltransferase (b3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom. J.Biol.Chem., 274: 12499-12507, 1999.

  17. Kaneko, M., Kudo, T., Iwasaki, H., Ikehara, Y., Nishihara, S., Nakagawa, S., Sasaki, K., Shiina, T., Inoko, H., Saitou, N. and Narimatsu, H.: a1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX. FEBS Lett., 452: 237-242, 1999.

  18. Togayachi, A., Kudo, T., Ikehara, Y., Iwasaki, H., Nishihara, S., Andoh, T., Higashiyama, M., Kodama, K., Nakamori, S. and Narimatsu, H.: Up-regulation of Lewis enzyme (Fuc-TIII) and plasma-type a1,3fucosyltransferase (Fuc-TVI) expression determines the augmented expression of sialyl Lewis x antigen in non-small cell lung cancer. Int.J.Cancer, 83: 70-79, 1999.

  19. Yamada, Y., Itano, N., Narimatsu, H., Kudo, T., Hirohashi, S., Ochiai, A., Niimi, A., Ueda, M. and Kimata, K.: Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction. Jpn.J.Cancer Res., 90: 987-992, 1999.

  20. Kaneko, M., Kudo, T., Iwasaki, H., Shiina, T., Inoko, H., Kozaki, T., Saitou, N. and Narimatsu, H.: Assignment of the human a1,3-fucosyltransferase IX gene (FUT9) to chromosome band 6q16 by in situ hybridization. Cytogenet.Cell.Genet., 86: 329-330, 1999.

  21. Ikehara, Y., Kojima, N., Kurosawa, N., Kudo, T., Kono, M., Nishihara, S., Issiki, S., Morozumi, K., Itzkowitz, S., Tsuda, T., Nishimura, S.I., Tsuji, S. and Narimatsu, H.: Cloning and expression of a human gene encoding an N-acetylgalactosamine- a 2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens. Glycobiology, 9: 1213-1224, 1999.

  22. Nakayama, F., Teraki, Y., Kudo, T., Togayachi, A., Iwasaki, H., Tamatani, T., Nishihara, S., Mizukawa, Y., Shiohara, T. and Narimatsu, H.: Expression of cutaneous lymphocyte-associated antigen regulated by a set of glycosyltransferases in human T cells: involvement of a1, 3-fucosyltransferase VII and b1,4-galactosyltransferase I. J.Invest.Dermatol., 115: 299-306, 2000.

  23. Nakayama, F., Nishihara, S., Iwasaki, H., Kudo, T., Okubo, R., Kaneko, M., Nakamura, M., Karube, M., Sasaki, K. and Narimatsu, H.: CD15 expression in mature granulocytes is determined by a 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by a 1,3-fucosyltransferase IV. J.Biol.Chem, 276: 16100-16106, 2001.

  24. Togayachi, A., Akashima, T., Ookubo, R., Kudo, T., Nishihara, S., Iwasaki, H., Natsume, A., Mio, H., Inokuchi, J., Irimura, T., Sasaki, K. and Narimatsu, H.: Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide b1,3-N-acetylglucosaminyltransferase (b3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids. J.Biol.Chem., 276: 22032-22040, 2001.

  25. Shimoda, Y., Tajima, Y., Osanai, T., Katsume, A., Kohara, M., Kudo, T., Narimatsu, H., Takashima, N., Ishii, Y., Nakamura, S., Osumi, N. and Sanai, Y.: Pax6 controls the expression of Lewis x epitope in the embryonic forebrain by regulating a 1,3-fucosyltransferase IX expression. J.Biol.Chem., 277: 2033-2039, 2002.

  26. Iwai, T., Inaba, N., Naundorf, A., Zhang, Y., Gotoh, M., Iwasaki, H., Kudo, T., Togayachi, A., Ishizuka, Y., Nakanishi, H. and Narimatsu, H.: Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide b,3-N-acetylglucosaminyltransferase (b3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. J.Biol.Chem., 27: 12802-12809, 2002.

  27. Gotoh, M., Yada, T., Sato, T., Akashima, T., Iwasaki, H., Mochizuki, H., Inaba, N., Togayachi, A., Kudo, T., Watanabe, H., Kimata, K. and Narimatsu, H.: Molecular cloning and characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N-acetylgalactosamine. J.Biol.Chem., 277: 38179-38188, 2002.

  28. Gotoh, M., Sato, T., Akashima, T., Iwasaki, H., Kameyama, A., Mochizuki, H., Yada, T., Inaba, N., Zhang, Y., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Nishihara, S., Watanabe, H., Kimata, K. and Narimatsu, H.: Enzymatic synthesis of chondroitin with a novel chondroitin sulfate N-acetylgalactosaminyltransferase that transfers N-acetylgalactosamine to glucuronic acid in initiation and elongation of chondroitin sulfate synthesis. J.Biol.Chem., 277: 38189-38196, 2002.

  29. Kudo, T., Iwai, T., Kubota, T., Iwasaki, H., Takayama, Y., Hiruma, T., Inaba, N., Zhang, Y., Gotoh, M., Togayachi, A. and Narimatsu, H.: Molecular cloning and characterization of a novel UDP-Gal:GalNAc(a) peptide b1,3-galactosyltransferase (C1Gal-T2), an enzyme synthesizing a core 1 structure of O-glycan. J.Biol.Chem., 277: 47724-47731, 2002.

  30. Cheng, L., Tachibana, K., Zhang, Y., Guo, J., Kahori Tachibana, K., Kameyama, A., Wang, H., Hiruma, T., Iwasaki, H., Togayachi, A., Kudo, T. and Narimatsu, H.: Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10. FEBS Lett., 531: 115-121, 2002.

  31. Zhang, Y., Iwasaki, H., Wang, H., Kudo, T., Kalka, T.B., Hennet, T., Kubota, T., Cheng, L., Inaba, N., Gotoh, M., Togayachi, A., Guo, J., Hisatomi, H., Nakajima, K., Nishihara, S., Nakamura, M., Marth, J.D. and Narimatsu, H.: Cloning and characterization of a new human UDP-N-acetyl-a-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen. J.Biol.Chem., 278: 573-584, 2003.

  32. Iwasaki, H., Zhang, Y., Tachibana, K., Gotoh, M., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Kubota, T. and Narimatsu, H.: Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-a-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2. J.Biol.Chem., 278: 5613-5621, 2003.

  33. Sato, T., Gotoh, M., Kiyohara, K., Akashima, T., Iwasaki, H., Kameyama, A., Mochizuki, H., Yada, T., Inaba, N., Togayachi, A., Kudo, T., Asada, M., Watanabe, H., Imamura, T., Kimata, K. and Narimatsu, H.: Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate. J.Biol.Chem., 278: 3063-3071, 2003.

  34. Inaba, N., Hiruma, T., Togayachi, A., Iwasaki, H., Wang, X.H., Furukawa, Y., Sumi, R., Kudo, T., Fujimura, K., Iwai, T., Gotoh, M., Nakamura, M. and Narimatsu, H.: A novel I-branching b -1,6-N-acetylglucosaminyltransferase involved in human blood group I antigen expression. Blood, 101: 2870-2876, 2003.

  35. Wang, H., Tachibana, K., Zhang, Y., Iwasaki, H., Kameyama, A., Cheng, L., Guo, J., Hiruma, T., Togayachi, A., Kudo, T., Kikuchi, N. and Narimatsu, H.: Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14. Biochem.Biophys.Res.Commun., 300: 738-744, 2003.

  36. Nishihara, S., Iwasaki, H., Nakajima, K., Togayachi, A., Ikehara, Y., Kudo, T., Kushi, Y., Furuya, A., Shitara, K. and Narimatsu, H.: a1,3-fucosyltransferase IX (Fut9) determines Lewis X expression in brain. Glycobiology, 13: 445-455, 2003.

  37. Yada, T., Gotoh, M., Sato, T., Shionyu, M., Go, M., Kaseyama, H., Iwasaki, H., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Watanabe, H., Narimatsu, H. and Kimata, K.: Chondroitin Sulfate Synthase - 2 : Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities. J.Biol.Chem., 278: 30235-30247, 2003.

  38. Isshiki, S., Kudo, T., Nishihara, S., Ikehara, Y., Togayachi, A., Furuya, A., Shitara, K., Kubota, T., Watanabe, M., Kitajima, M. and Narimatsu, H.: Lewis type 1 antigen synthase (b3Gal-T5) is transcriptionally regulated by homeoproteins. J.Biol.Chem., 278: 36611-36620, 2003.

  39. Yada, T., Sato, T., Kaseyama, H., Gotoh, M., Iwasaki, H., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Watanabe, H., Narimatsu, H., Kimata, K.: Chondroitin sulfate synthase-3: Molecular cloning and characterization. J. Biol. Chem. 278: 39711-39725, 2003.

  40. Sato, T., Gotoh, M., Kiyohara, K., Kameyama, A., Kubota, T., Kikuchi, N., Ishizuka, Y., Iwasaki, H., Togayachi, A., Kudo, T., Ohkura, T., Nakanishi, H., Narimatsu, H.: Molecular cloning and characterization of a novel human b1,4-N-acetylgalactosaminyltransferase, b4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, GalNAc b1-4GlcNAc. J Biol Chem. 2003

  41. Yamada, Y., Itano, N., Narimatsu, H., Kudo, T., Hirohashi, S., Ochiai, A., Tohnai, I., Ueda, M., Kimata, K.: CD44 variant exon 6 expressions in colon cancer assessed by quantitative analysis using real time reverse transcriptase-polymerase chain reaction. Oncol Rep. 10:1919-1924, 2003.

  42. Yamada, Y., Itano, N., Narimatsu, H, Kudo, T., Morozumi, K., Hirohashi, S., Ochiai, A., Ueda, M., Kimata, K.:Elevated transcript level of hyaluronan synthase1 gene correlates with poor prognosis of human colon cancer. Clin Exp Metastasis. 2004;21(1):57-63.

  43. Kudo ,T, Kaneko ,M., Iwasaki, H., Togayachi, A., Nishihara, S., Abe, K., Narimatsu, H. :Normal Embryonic and Germ Cell Development in Mice Lacking alpha1,3-Fucosyltransferase IX (Fut9) Which Show Disappearance of Stage-Specific Embryonic Antigen 1. Mol Cell Biol. 2004 May 15;24(10):4221-4228.

  44. Cheng, L., Tachibana, K., Iwasaki, H., Kameyama, A., Zhang, Y., Kubota, T., Hiruma, T., Tachibana, K., Kudo, T., Guo, JM., Narimatsu, H. :Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T15.FEBS Lett. May 21;566(1-3):17-24,2004.

  45. Ishida H, Togayachi A, Sakai T, Iwai T, Hiruma T, Sato T, Okubo R, Inaba N, Kudo T, Gotoh M, Shoda J, Tanaka N, Narimatsu H.
    A novel beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer.FEBS Lett. 2005 Jan 3;579(1):71-78.

  46. Iwai T, Kudo T, Kawamoto R, Kubota T, Togayachi A, Hiruma T, Okada T, Kawamoto T, Morozumi K, Narimatsu H.
    Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells.
    Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4572-4577.

  47. Zhang C, Moriguchi T, Kajihara M, Esaki R, Harada A, Shimohata H, Oishi H, Hamada M, Morito N, Hasegawa K, Kudo T, Engel JD, Yamamoto M, Takahashi S. MafA is a key regulator of glucose-stimulated insulin secretion.
    Mol Cell Biol. 2005 Jun;25(12):4969-4976.

  48. Comelli EM, Head SR, Gilmartin T, Whisenant T, Haslam SM, North SJ, Wong NK, Kudo T, Narimatsu H, Esko JD, Drickamer K, Dell A, Paulson JC. A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology. 16,117-131,2006.

  49. Shimohata H, Yoh K, Morito N, Shimano H, Kudo T, Takahashi S.MafK overexpression in pancreatic beta-cells caused impairment of glucose-stimulated insulin secretion.Biochem Biophys Res Commun. 346,671-80. 2006.

  50. Moriguchi T, Hamada M, Morito N, Terunuma T, Hasegawa K, Zhang C, Yokomizo T, Esaki R, Kuroda E, Yoh K, Kudo T, Nagata M, Engel JD, Yamamoto M, Takahashi S. MafB is essential for renal development and F4/80 expression in macrophage. Mol Cell Biol. 26, 5715-5727, 2006.

  51. Kudo T, Fujii T, Ikegami S, Inokuchi K, Takayama Y, Ikehara Y, Nishihara S, Togayachi A, Takahashi S, Tachibana K, Yuasa S, Narimatsu H. Mice lacking alpha1,3-fucosyltransferase IX demonstrate disappearance of Lewis x structure in brain and increased anxiety-like behaviors.Glycobiology. 17, 1-9, 2007.

  52. Matsumura H, Kudo K, Harada A, Esaki R, Suzuki H, Kato M, Takahashi S. Suppression of MafA dependent transcription by transforming growth factor-β signaling. Biochem Biophys Res Commun . 364, 151-156, 2007

  53. Tanimoto Y, Iijima S, Suzuki Y, Daitoku Y, Hasegawa Y, Mizuno S, Ishige T, Kudo T, Takahashi S, Kunita S, Sugiyama F, Yagami K-i. Embryonic stem cells derived from C57BL/6J and C57BL/6N. Comparative Medicine. 58, 347-352, 2008.

  54. Takeuchi T, Kudo T, Ogata K, Hamada M, Nakamura M, Kito K, Abe Y, Ueda N, Yamamoto M, Engel JD, Takahashi S. Neither MafA/L-Maf nor MafB is essential for lens development in mice. Genes Cells. 14: 941-947, 2009.  

  55. Nakamura M, Hamada M, Hasegawa K, Kusakabe M, Suzuki H, Greaves DR, Moriguchi T, Kudo T, Takahashi S. c-Maf is essential for the F4/80 expression in macrophages in vivo. Gene. 445: 66-72, 2009.

  56. Shimohata H, Yoh K, Fujita A, Morito N, Hirayama K, Kobayashi M, Kudo T, Yamagata K. Takahashi S. MafA-deficient and beta cell-specific MafK-overexpressing hybrid transgenic mice develop humen-like severe diabetic nephropathy. Biochem Biophys Res Commun. 389: 235-240, 2009.

  57. Togayachi A, Kozono Y, Ikehara Y, Ito H, Suzuki N, Tsunoda Y, Abe S,Sato T, Nakamura K, Suzuki M, Goda H, Ito M, Kudo T, Takahashi S, Narimatsu H. Lack of lacto/neolacto-glycolipids enhances the formation of glycolipid-enriched microdomains, facilitating B cell activation. Proc Natl Acad Sci USA. 107: 11900-11905, 2010.

  58. Noso S, Kataoka K, Kawabata Y, Babaya N, Hiromine Y, Yamaji K, Fujisawa T, Aramata S, Kudo T, Takahashi S, Ikegami H. Insulin transactivator MafA regulates intra-thymic expression of insulin and affects susceptibility to type 1 diabetes. Diabetes, 59: 2579-2587, 2010.

  59. Morito N, Yoh K, Maeda A, Nakano T, Fujita A , Kusakabe M, Hamada M, Kudo T, Yamagata K, Takahashi S. A novel transgenic mouse model of the human multiple myeloma chromosomal translocation t(14;16)(q32;q23). Cancer Res, 71: 339-348, 2011.

  60. Sato T, Kudo T, Ikehara Y, Ogawa H, Hirano T, Kiyohara K, Hagiwara K,  Togayachi A, Ema M, Takahashi S, Kimata K, Watanabe H, Narimatsu H. Chondroitin sulfate N-acetylgalactosaminyltransferase 1 deficient mice displays dwarfism with epiphyseal plate abnormalities. J Biol Chem, 286: 5803-5812, 2011.

  61. Kusakabe M, Hasegawa K, Hamada M, Nakamura M, Ohsumi T, Suzuki H, Tran TNM, Kudo T, Uchida K, Ninomiya H, Chiba S, Takahashi S. c-Maf plays a crucial role for the definitive erythropoiesis that accompanies erythroblastic island formation in the fetal liver. Blood, 118, 1374-1385, 2011.

  62. Sekiguchi Y, Owada J, Oishi H, Katsumata T, Ikeda K, Kudo T, Takahashi S. Non-invasive monitoring of beta-cell mass and fetal beta-cell genesis in mice using bioluminescence imaging. Exp.Anim., 61, 445-451, 2012.

  63. Katsumata T, Oishi H, Sekiguchi Y, Nagasaki H, Daasi D, Ema M, Kudo T, Takahashi S. Bioluminescence imaging of beta-cells and intrahepatic insulin gene activity under normal and pathological conditions. PLOS ONE, 8, e60411, 2013.

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(和文)       

  1. 木村博久、西原祥子、工藤崇、玉谷卓也、成松久:α1,3フコース転移酵素(α1,3FT)遺伝子導入による培養細胞の糖脂質組成変化とセレクチン結合能の獲得、脂質生化学研究, 38: 195-198,1996

  2. 西原祥子、新屋直子、平賀恒男、池原譲、岩崎裕子、工藤崇、諸角強英、成松久:ゴルジ膜貫通部位に変異(Leu20 to Arg)をもつα1,3/4フコース転移酵素(Fuc-TIII)の解析と大腸組織におけるルイス抗原の発現、腫瘍マーカー研究会雑誌, 12: 169-171, 1997

  3. 工藤崇、池原譲、西原祥子、諸角強英、渡邊昌彦、成松久:大腸組織におけるルイス式血液型抗原とα1,2フコース転移酵素発現の検討、腫瘍マーカー研究会雑誌, 12: 163-166, 1997

  4. 池原譲、工藤崇、西原祥子、一色聡一郎、久保田哲朗、服部隆則、成松久:分泌型酵素(α1,2フコース転移酵素)による単純ムチンT抗原のフコシル化と、胃癌細胞におけるT抗原の発現の検討、腫瘍マーカー研究会雑誌, 12: 159-162, 1997

  5. 池原譲、西原祥子、工藤崇、平賀恒男、諸角強英、柴多三省、池田佳文、一色聡一郎、久保田哲朗、成松久、腸上皮化生に出現するLea抗原はルイス酵素(Fuc-TIII)の発現の上昇による、腫瘍マーカー研究会雑誌, 13: 69-73,1998

  6. 岩崎裕子、工藤崇、西原祥子、池原譲、菅野康吉、安藤秋子、大倉久直、成松久、CA19-9、DU-PAN-2値に対するSe、Le 遺伝子のgene dosage effect 、腫瘍マーカー研究会雑誌, 13: 61-64, 1998

  7. 西原祥子、池原譲、平賀恒男、栂谷内晶、工藤崇、中森正二、諸角強英、成松久、ヒト膵臓癌組織におけるシアリルルイス抗原の発現と合成に関わる各種糖転移酵素の解析、腫瘍マーカー研究会雑誌, 13: 57-59,1998

  8. 池原譲、小島直也、工藤崇、西原祥子、諸角強英、辻崇一、成松久、癌関連糖鎖抗原STn抗原を合成するシアル酸転移酵素(human ST6GalNAc I)遺伝子のクローニング、腫瘍マーカー研究会誌、14: 21-22,1999

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(著書) 

  1. 栂谷内晶、菊池紀広、工藤崇、成松久:「糖鎖修飾を決定する糖転移酵素の網羅的解析」(分担)蛋白質核酸酵素・増刊号「化学と生物学の接点がつくるNewバイオテクノロジー」、共立出版、2003年8月

  2. 工藤崇、成松久:「フコース転移酵素の機能」(分担)蛋白質核酸酵素・増刊号「糖鎖機能:第3の生命鎖」、共立出版、2003年6月

  3. 工藤崇、栂谷内晶、後藤雅式、成松久:「糖鎖遺伝子研究の現状と国際競争」(分担)バイオインダストリー「糖鎖工学の最前線」、シーエムシー出版、2002年12月

  4. 工藤崇、西原祥子、成松久:「b-1,4-Gal転移酵素」(分担)細胞工学・別冊「グライコバイオロジー実験プロトコール」、秀潤社、1996年9月

  5. 西原祥子、工藤崇、成松久:「a-1,3-Fuc転移酵素」(分担)細胞工学・別冊「グライコバイオロジー実験プロトコール」、秀潤社、1996年9月

  6. 西原祥子、工藤崇、成松久:「ヒトにおけるフコース転移酵素変異体の解析」(分担)細胞工学・6月号「糖鎖は生物の機能をどう決めているか」、秀潤社、1996年6月

  7. 工藤崇、栂谷内晶、成松久:「フコース転移酵素}(分担)「未来に拓く糖鎖科学」金芳堂、2005年12月

  8. T. Kudo, H. Narimatsu : "Fucosyltransferase" , Taniguchi et al. Eds. "Experimental Glycoscience, Glycobiology", Springer, 2008

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