Contact

1-1-1 tennodai,tsukuba-shi,ibaraki-ken 305-8575, JAPAN
Laboratory of Gene Regulation
Graduate School of Comprehensive Human Sciences
University of Tsukuba

Publication

Recent Presentations in Conference

  • Honda S., Fukuda A., Mizuno S., Sugiyama F., Hayashi Y., Nishimura K., Hisatake K. "Production of a non-invasive monitoring system of Uncoupling protein 1-expressing adipocytes" Tsukuba Global Science Week 2017, Tsukuba, September, 2017
  • Bui PL., Nishimura K., Hisatake K. "Mechanistic analysis of the initiation of retroviral gene silencing by reprogramming factors" Tsukuba Global Science Week 2017, Tsukuba, September, 2017
  • Nishimura K., Hisatake K., Ishiwata H. "新規顕微鏡システムを用いた非染色・非侵襲な多能性定量系の開発" The 16th Congress of the Japanese Society for Regenerative Medicine, Sendai, March, 2017
  • Aizawa S, Bui PL, Nishimura K, Hisatake K "Establishment of a system to analyze X chromosome activation status for analysis of iPSC generation mechanism." The 16th Congress of the Japanese Society for Regenerative Medicine, Sendai, March, 2017
  • Nishimura K., Aizawa S., Nugroho FL、Sakuragi Y.,Ohtaka M.,Fukuda A., Nakanishi M., Hisatake K. "Tcl1-Aktを介したKlf4による代謝リプログラミングはiPS細胞の多能性を向上させる" The 39th annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, December, 2016
  • Aizawa S, Bui PL, Nishimura K, Hisatake K "Establishment of a system to analyze X chromosome reactivation during iPS cell production" The 39th annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, December, 2016
  • Aizawa S, Bui PL, Nishimura K, Hisatake K "A quantitative method for analysis of X chromosome reactivation in iPSC production" TGSW(Tsukuba Global Science Week)2016, Tsukuba, September, 2016
  • Hayashi Y, “Cell-Autonomous Correction of Ring Chromosomes in Human Induced Pluripotent Stem Cells” TERMIS-AP 2016, Taipei, September 3–6, 2016
  • Nishimura K, Liliani NF, Shiomitsu E, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K:Molecular mechanism of KLF4-dose dependent induction of pluripotency during iPSC production、CiRA/ISSCR International Symposium, Kyoto, March, 2016
  • Hisatake K, Lilliani NF, Shiomitsu E, Ohtaka M, Fukuda A, Nakanishi M, Nishimura K “Manipulation of KLF4 expression reveals a mechanistic insight into an intermediate state of reprogramming” The 38th annual meeting of MBSJ (the Molecular Biology Society of Japan), Kobe, December, 2015
  • Bui PL., Nishimura K., Fukuda A.,Hisatake K. " Mechanism of X chromosome reactivation during reprogramming" Tsukuba Global Science Week 2015, Tsukuba, September, 2015
  • Nishimura K, Shiomitsu E, Liliani N.F., Kato T, Chen C, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.“Manipulation of KLF4 expression generates iPSCs paused at successive stages of reprogramming”International Society of Stem Cell Research 13th Annual Meeting, Stockholm, Sweden, June 25, 2015
  • Nishimura K,Kato T, C. Chen, L. Oinam, Shiomitsu E, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.“Paused iPSCを用いたiPS細胞誘導過程の解析”The 14th Congress of the Japanese Society for Regenerative Medicine, Yokohama, March 2015
  • Kato T,Nishimura K,Nguyen Thuy Linh, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.“iPS細胞誘導初期に関与する転写因子の同定とその機能解析”The 14th Congress of the Japanese Society for Regenerative Medicine, Yokohama, March 2015
  • Shiomitsu E, Nishimura K, Lalhaba Oinam、Fransiska Liliani, Fukuda A, Hisatake K.“細胞の初期化におけるリプログラム因子の機能解析”The 14th Congress of the Japanese Society for Regenerative Medicine, Yokohama, March 2015
  • Nishimura K,Kato T, C. Chen, L. Oinam, Shiomitsu E, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.“Klf4遺伝子発現量調節による多能性が異なるiPS細胞の誘導” The 37th annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, November 25, 2014
  • T. Kato, L. Oinam, E. Shiomitsu, A. Fukuda, K. Nishimura, K. Hisatake. "Mechanistic analysis of the early phase of iPSC production" The 13th Joint Mini-Symposium 2014 of NTU, KU and UT、September 26, 2014 (Tsukuba)
  • Nishimura K,Kato T, Oinam L, Shiomitsu E, Narita T, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.“初期化が途中で停止した細胞を用いたiPS細胞誘導過程の解析”The 13th Congress of the Japanese Society for Regenerative Medicine, Kyoto, March 2014
  • Kato T, Oinam L, Shiomitsu E,Fukuda A, Nakanishi M, Nishimura K, Hisatake K.“iPS細胞誘導初期における体細胞特異的転写因子の発現減少と誘導効率への影響”The 13th Congress of the Japanese Society for Regenerative Medicine, Kyoto, March 2014
  • Shiomitsu E, Nishimura K, Kato T, Oinam L, Fukuda A, Hisatake K.“Analysis of the Partially Reprogrammed iPS Cells” The 12th NTU-Japan International Student Mini-Symposium on Life Science、December 21, 2013(Taiwan)
  • Kato T,Nishimura K, Shiomitsu E, Ayakawa D, Fukuda A, Hisatake K.“iPS細胞誘導初期におけるメカニズム解析” The 36th annual meeting of MBSJ (the Molecular Biology Society of Japan), Kobe, December 3, 2013
  • Nishimura K,Kato T, Oinam L, Shiomitsu E, Narita T, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.“Klf4遺伝子発現量による初期化が途中で停止した細胞の誘導”The 36th annual meeting of MBSJ (the Molecular Biology Society of Japan), Kobe, December 3, 2013
  • Nishimura K, Kato T, Oinam L, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.
    “Manipulation of Klf4 expression produces snap shots of iPSC induction” CSHAsia 2013 Conference on CSHA/ISSCR Joint Meeting on Stem Cells in Science and Medicine, Suzhou Dushu Lake Conference Center (China)、October 14, 2013
  • Hisatake K, Kato T, Oinam L, Narita T, Ohtaka M, Fukuda A, Nakanishi M, Nishimura K.
    “Regulated Induction of Partially Reprogrammed iPS Cells by SeVdp Vectors” Cold Spring Harbor Laboratory meeting on “Stem Cell Biology”, New York (USA), September 25, 2013
  • Nishimura K, Kato T, Oinam L, Narita T, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.
    “Taking snap shots during iPSC production by SeVdp vectors”
    International Society of Stem Cell Research 11th Annual Meeting, Boston, June 14, 2013
  • Nishimura K, Narita T, Ohtaka M, Takayasu S, Sano M, Fukuda A, Nakanishi M, Hisatake K
    “SeVdpベクターを用いたiPS細胞の品質調節メカニズムの解析”
    The 12th Congress of the Japanese Society for Regenerative Medicine, Yokohama, March 2013
  • Nishimura K.
    “Application of Cytoplasmic RNA vector Developed from Noncytopathic RNA Viruses to Stem Cell Engineering”
    The 2nd Meeting on RNA and Biofunctions-Asia Study, Fukuoka, January, 2013
  • Fukuda A, Nakadai T, Shimada M, Nishimura K, Hisatake K.
    “The RNA-binding protein complexes NF45/90 and NF45/110 activate c-fos transcription in a signal-dependent way”
    The 35th annual meeting of MBSJ (the Molecular Biology Society of Japan), Fukuoka, December 12, 2012
  • Nishimura K, Ohtaka M, Takayasu S, Sano M, Hisatake K, Nakanishi M.
    “QUALITY CONTROL OF IPS CELLS BY UNIQUE GENE TRANSFER SYSTEM”
    International Society of Stem Cell Research 10th Annual Meeting, Yokohama, June, 2012
  • 西村健、大高真奈美、高安聡子、佐野将之、久武幸司、中西真人
    “RNA工学とウイルス学の融合による簡便かつ高効率なiPS細胞樹立方法の確立”
    The 34th annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, December 13-16, 2011
  • 古田美玲、内田恵理子、中西真人、西村健、大高真奈美、山口照英
    “gp91phox搭載持続発現型センダイウイルスベクターによるX-CGDモデルマウス細胞の活性酸素産生機構の回復”
    The 34th annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, December 13-16, 2011
  • 城本悠助、宮川ー倉持さとみ、勝俣明子、西村健、中野徹
    “精子幹細胞を用いたpiRNA産生機構の解析”
    The 34th annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, December 13-16, 2011
  • Fukuda A, Shimada M, Nakadai T, Nishimura K, Hisatake K.
    “Heterogeneous nuclear ribonucleoprotein R (hnRNP R) cooperates with Mediator to enhance transcription reinitiation”
    The 34th annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, December 13-16, 2011
  • Nishimura K, Ohtaka M, Sano M, Hisatake K, Nakanishi M.
    “Novel Cytoplasmic persistent expression RNA vector developed by combination of RNA biotechnology and virology” <br />
    NTU-JST Joint Meeting on RNA and Biofunctions - Asia Studies, Taiwan, November 10-12, 2011
  • Nishimura K.
    “Development of Novel Cytoplasmic RNA Vectors Capable of Stable Gene Expression without Chromosomal Integration” <br />
    The 2nd Leading Graduate Schools International Conference, Tsukuba, November 1, 2011
  • Fukuda A, Takeuchi M, Nakadai T, Shimada M, Nishimura K, Hisatake K.
    “Activation of multiple-round transcriptions by a novel coactivator hnRNP R and Mediator”
    Cold Spring Harbor Laboratory meeting on “Mechanisms of Eukaryotic Transcription”New York, August 30-September 3, 2011
  • Fukuda A, Takeuchi M, Nakadai T, Shimada M, Hisatake K.
    “Mechanistic analysis of c-fos transcriptional regulation by a novel coactivator hnRNP R”
    The 33rd annual meeting of MBSJ (the Molecular Biology Society of Japan) & The 83rd annual meeting of JBS (the Japanese Biochemical Society), Kobe, December 7-10, 2010
  • Nakadai T, Fukuda A, Takeuchi M, Shimada M, Hisatake K.
    “Mechanistic analyses of transcriptional regulation of the c-fos gene via the NF complexes”
    The 33rd annual meeting of MBSJ (the Molecular Biology Society of Japan) & The 83rd annual meeting of JBS (the Japanese Biochemical Society), Kobe, December 7-10, 2010
  • Hisatake K, Takeuchi M, Nakadai T, Shimada M, Fukuda A.
    “Mechanism of c-fos transcriptional regulation by an RNA-binding protein hnRNP R”
    ASBMB Special Symposia“Transcriptional Regulation by Chromatin and RNA polymerase II”, Granlibakken, Tahoe, USA, September 30 - October 4, 2010
  • Fukuda A, Takeuchi M, Nakadai T, Shimada M, Hisatake K.
    “Mechanistic analysis of c-fos transcriptional regulation by a novel coactivator hnRNP R”
    9th EMBL Conference“Transcription and Chromatin”, Heidelberg, Germany, August 28-31, 2010
  • Fukuda A, Nakadai T, Shimada M, Hisatake K.
    “Transcriptional regulation of c-fos gene via RNA binding proteins”
    The 32nd annual meeting of MBSJ (the Molecular Biology Society of Japan), Yokohama, December 9-12, 2009
  • Fukuda A, Nakadai T, Shimada M, Hisatake K.
    “RNA binding proteins regulate the c-fos transcription”
    Cold Spring Harbor Laboratory meeting on “Mechanisms of Eukaryotic Transcription”, New York, August 25-29, 2009
  • Fukuda A, Nakadai T, Shimada M, Hisatake K.
    “Transcriptional Regulation by RNA Binding Proteins”
    The regular meeting of the Biochemistry Society of Kantoh, Tsukuba, June 20, 2009
  • Fukuda A, Nakadai T, Shimada M, Hisatake K.
    “Identification and functional analysis of novel coactivators for c-fos gene transcription”
    The 31st annual meeting of MBSJ (the Molecular Biology Society of Japan) & The 81st annual meeting of JBS (the Japanese Biochemical Society), Kobe, December 9-12, 2008
  • Hisatake K, Shimada M, Nakadai T, Fukuda A.
    “Regulatory mechanisms of histone H3 phosphorylation by MSK1”
    The 31st annual meeting of MBSJ & The 81st annual meeting of JBS, Kobe, December 9-12, 2008
  • Fukuda A, Nakadai T, Shimada M, Hisatake K.
    “Identification of Novel Coactivator Activities for c-fos Gene Transcription”
    ASBMB Special Symposia, Granlibakken, Lake Tahoe, October 16-20, 2008