研究成果

2013年度

班員名著者タイトル雑誌名PubMed発行年和文概要
A01-1
永田恭介
A02-06
加藤哲久
Imamura K, et al.Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.Mol Cell245077152014
A01-1
永田恭介
Binh NT, et al.Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition.Biochem Biophys Res Commun.243618822014
A01-1
永田恭介
Binh NT, et al.The N-terminal region of influenza virus polymerase PB1 adjacent to the PA binding site is involved in replication but not transcription of the viral genome.Front Microbiol.243916322013
A01-1
永田恭介
Ueshima S, et al.Upstream binding factor-dependent and pre-rRNA transcription-independent association of pre-rRNA processing factors with rRNA gene.Biochem Biophys Res Commun.242698112014
A01-1
永田恭介
Hisaoka M, et al.Intrinsically disordered regions of nucleophosmin/B23 regulate its RNA binding activity through their inter- and intra-molecular association.Nucleic Acids Res.241060842014
A01-1
永田恭介
Komatsu T, et al.DNA replication-dependent binding of CTCF plays a critical role in adenovirus genome functions.Sci Rep.238519262013
A01-1
永田恭介
Haruyama T, et al.Anti-influenza virus activity of Ginkgo biloba leaf extracts.J Nat Med.231793172013
A01-1
朴三用
Cho KJ, et al.Insight into structural diversity of influenza virus hemagglutinin.J Gen Virol.236368242013
A01-1
朴三用
Kikuchi J, et al.Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding.PLoS One235932712013
A01-1
朴三用
Rahman MM, et al.Roles of conserved Arg(72) and Tyr(71) in the ascorbate-specific transmembrane electron transfer catalyzed by Zea mays cytochrome b561. J Biosci Bioeng.232904472013
A01-2
脇田隆字
Sakata K, et al.HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor.Sci Rep.242638612013
A01-2
脇田隆字
Okamoto Y, et al.Hepatitis virus infection affects DNA methylation in mice with humanized livers.Gastroenterology241841332014
A01-2
脇田隆字
Nishimura Y, et al.Enterovirus 71 binding to PSGL-1 on leukocytes: VP1-145 acts as a molecular switch to control receptor interaction.PLoS Pathog.239354882013
A01-2
脇田隆字
Suzuki R, et al.Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.PLoS Pathog.240095102013
A01-2
脇田隆字
Watashi K, et al.Interleukin-1 and tumor necrosis factor-alpha trigger restriction of hepatitis B virus infection via a cytidine deaminase (AID).J Biol Chem.240253292013
A01-2
脇田隆字
Maehama T, et al.A class II phosphoinositide 3-kinase plays an indispensable role in hepatitis C virus replication.Biochem Biophys Res Commun.240550312013
A01-2
脇田隆字
Nakajima S, et al.Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives.Biochem Biophys Res Commun.240997742013
A01-2
脇田隆字
Shiota T, et al.The hepatitis E virus capsid C-terminal region is essential for the viral life cycle: implication for viral genome encapsidation and particle stabilization.J Virol.234684812013
A01-2
脇田隆字
Arita M, et al.Oxysterol-binding protein family I is the target of minor enviroxime-like compounds.J Virol.233654452013
A01-2
脇田隆字
Abe Y, et al.Thromboxane A2 synthase inhibitors prevent production of infectious hepatitis C virus in mice with humanized livers.Gastroenterology236847502013
A01-2
脇田隆字
Suzuki R, et al.Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon.J Gen Virol.240963192014
A01-2
脇田隆字
Matsumoto Y, et al.Antiviral activity of glycyrrhizin against hepatitis C virus in vitro.PLoS One238748432013
A01-2
脇田隆字
Akazawa D, et al.Neutralizing antibodies induced by cell culture-derived hepatitis C virus protect against infection in mice.Gastroenterology236733552013
A01-2
竹安邦夫
Kotani T, et al.Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes.Nucleic Acids Res.233964482013
A01-2
竹安邦夫
Suzuki Y, et al.Visualization of structural changes accompanying activation of N-methyl-D-aspartate (NMDA) receptors using fast-scan atomic force microscopy imaging.J Biol Chem..232233362013
A01-2
竹安邦夫
Yoshimura SH, et al.Intermolecular disulfide bonds among nucleoporins regulate karyopherin-dependent nuclear transport.J Cell Sci.236410692013
A01-2
竹安邦夫
Hirai Y, et al.Nucleolar scaffold protein, WDR46, determines the granular compartmental localization of nucleolin and DDX21.Genes Cells238481942013
A01-2
竹安邦夫
Maruyama H, et al.An alternative beads-on-a-string chromatin architecture in Thermococcus kodakarensis.EMBO Rep.238355082013
A01-2
竹安邦夫
Yadav T, et al.Bacillus subtilis DprA recruits RecA onto ssDNA and mediates annealing of complementary ssDNA strands coated by SsbB and SsbA.J Biol Chem..237791062013
A01-2
竹安邦夫
Alonso JC, et al.Early steps of double-strand break repair in Bacillus subtilis.DNA Repair (Amst).233805202013
A01-2
竹安邦夫
Gilmore JL, et al.AFM investigation of the organization of actin bundles formed by actin-binding proteins.Journal of Surface Engineered Materials and Advanced Technology (JSEMAT)2013
A01-2
竹安邦夫
Suzuki Y, et al.High-speed atomic force microscopy combined with inverted optical microscopy for studying cellular events.Sci Rep.238234612013
A01-2
竹安邦夫
Kumeta M, et al.Antibody-based analysis reveals "filamentous vs. non-filamentous" and "cytoplasmic vs. nuclear" crosstalk of cytoskeletal proteins.Exp Cell Res.239119882013
A01-2
竹安邦夫
Louvet E, et al.Probing the stiffness of isolated nucleoli by atomic force microscopy.Histochem Cell Biol.242974482013
A01-3
藤田尚志
A02-03
米山光俊
Nitta S, et al.Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immunity.Hepatology229115722013
A01-3
藤田尚志
A02-03
米山光俊
Takamatsu S, et al.Functional characterization of domains of IPS-1 using an inducible oligomerization system.PLoS One233082562013
A01-3
藤田尚志
A02-03
米山光俊
Hayashi Y, et al.Virus-induced expression of retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 in the cochlear sensory epithelium.Microbes Infect.236442302013
A01-3
藤田尚志
A01-5
小池智
A02-03
米山光俊
Ng CS, et al.Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses.J Virol.237852032013
A01-3
藤田尚志
Fung G, et al.Production of a dominant-negative fragment due to G3BP1 cleavage contributes to the disruption of mitochondria-associated protective stress granules during CVB3 infection.PLoS One242602472013
A01-3
高折晃史
Chonabayashi K, et al.Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3.Leukemia231686132013
A01-3
高折晃史
Matsui Y, et al.Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis.Virology244185402013
A01-3
高折晃史
Sato T, et al.Human CD1c+ myeloid dendritic cells acquire a high level of retinoic acid-producing capacity in response to vitamin D.J Immunol.239666312013
A01-3
高折晃史
Yoshioka S, et al.CCAAT/enhancer-binding protein β expressed by bone marrow mesenchymal stromal cells regulates early B-cell lymphopoiesis.Stem Cells241152412014
A01-3
高折晃史
Arai Y, et al.Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation.Biochem Biophys Res Commun.243260712014
A01-3
高折晃史
Mori F, et al.Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model.Eur J Haematol.241884162014
A01-3
高折晃史
A02-07
片平正人
Furukawa A, et al.Quantitative analysis of the location- and sequence-dependent deamination by APOBEC3G using real-time NMR.Angew Chem Int Ed Engl.244781362014
A01-4
柳雄介
Ito M, et al.Measles virus non-structural C protein modulates viral RNA polymerase activity by interacting with a host protein SHCBP1.J Virol.238046342013
A01-4
柳雄介
Shirogane Y, et al.Cooperation: another mechanism of viral evolution.Trends Microbiol.237643882013
A01-4
柳雄介
Nakatsu Y, et al.Intracellular transport of the measles virus ribonucleoprotein complex is mediated by Rab11A-positive recycling endosomes and drives virus release from the apical membrane of polarized epithelial cells.J Virol.234086172013
A01-4
柳雄介
Nakashima M, et al.Mutations in the putative dimer-dimer interfaces of the measles virus hemagglutinin head domain affect membrane fusion triggering.J Biol Chem.233622712013
A01-4
柳雄介
A02-13
小柴琢己
Ichinohe T, et al.Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection.Proc Natl Acad Sci USA241275972013
A01-4
荒瀬尚
Tanaka Y, et al.Herpesvirus 6 glycoproteins B (gB), gH, gL, and gQ are necessary and sufficient for cell-to-cell fusion.J Virol.238850762013
A01-4
荒瀬尚
Minami T, et al.Overcoming chemoresistance of small-cell lung cancer through stepwise HER2-targeted antibody-dependent cell-mediated cytotoxicity and VEGF-targeted antiangiogenesis.Sci Rep.240368982013
A01-4
荒瀬尚
A02-06
加藤哲久
Imai T, et al.Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells.PLoS One239512822013概要
A01-4
荒瀬尚
Arase N, et al.CD1a-positive familial cutaneous mastocytosis without germ-line or somatic mutations in c-kit.Br J Dermatol.238341232013
A01-4
荒瀬尚
Jin H, et al.Autoantibodies to IgG/HLA-DR complexes are associated with rheumatoid arthritis susceptibility.Proc Natl Acad Sci USA245673782014
A01-4
荒瀬尚
Haldar M, et al.Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.Cell246307242014
A01-5
小池智
Fujii K, et al.Transgenic mouse model for the study of enterovirus 71 neuropathogenesis.Proc Natl Acad Sci USA239599042013
A01-5
小池智
Yamayoshi D, et al.Functional comparison of SCARB2 and PSGL1 as receptors for enterovirus 71.J Virol.233028722013
A01-6
佐々木顕
Yamamichi M, et al.Timing and propagule size of invasion determine its success by a time-varying threshold of demographic regime shift.Ecology(in press)2014
A01-6
佐々木顕
Mpolya MA, et al.Epidemic dynamics of a vector-borne disease on a village-and-city star network with commuters.J Theor Biol.243212272014
A01-6
佐々木顕
Leimar O, et al.Limiting similarity, species packing, and the shape of competition kernels.J Theor Biol.239545482013
A01-6
佐々木顕
Omori R, et al.Timing of the emergence of new successful viral strains in seasonal influenza.J Theor Biol.235676502013
A01-7
小柳義夫
Ebina H, et al.Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus.Sci Rep.239746312013
A01-7
小柳義夫
Hollenbaugh JA, et al.Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells.PLoS Pathog.238259582013
A01-7
小柳義夫
Matsuzawa T, et al.Oral administration of the CCR5 inhibitor, maraviroc, blocks HIV ex vivo infection of Langerhans cells within epithelium.J Invest Dermatol.236485472013
A01-7
小柳義夫
Yoshida T, et al.Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 vpu is mediated by cytoplasmic domain interactions.J Virol.241092382013
A01-7
小柳義夫
Sato K, et al.HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo.PLoS Pathog.243397812013
A01-7
小柳義夫
Sakamoto T, et al.CKIP-1 is an intrinsic negative regulator of T-cell activation through an interaction with CARMA1.PLoS One244656892014
A02-01
高田礼人
Manzoor R, et al.Heat shock protein 70 modulates influenza A virus polymerase activity.J Biol Chem.244746932014
A02-01
高田礼人
Maruyama J, et al.Characterization of the envelope glycoprotein of a novel filovirus, lloviu virus.J Virol.241317112014
A02-01
高田礼人
Muramatsu M, et al.Comparison of antiviral activity between IgA and IgG specific to influenza virus hemagglutinin: increased potential of IgA for heterosubtypic immunity.PLoS One244656062014
A02-01
高田礼人
Yamaguchi H, et al.Role of the C-Terminal Region of Vervet Monkey Polyomavirus 1 VP1 in Virion Formation.J Vet Med Sci.244199752014
A02-01
高田礼人
Muleya W, et al.Molecular Epidemiology of Paramyxoviruses in Frugivorous Eidolon helvum Bats in Zambia.J Vet Med Sci.243897432014
A02-01
高田礼人
Noyori O, et al.Suppression of Fas-mediated apoptosis via steric shielding by filovirus glycoproteins.Biochem Biophys Res Commun.242395462013
A02-01
高田礼人
Noyori O, et al.Differential potential for envelope glycoprotein-mediated steric shielding of host cell surface proteins among filoviruses.Virology240745772013
A02-01
高田礼人
Muramatsu M, et al.Heterosubtypic antiviral activity of hemagglutinin-specific antibodies induced by intranasal immunization with inactivated influenza viruses in mice.PLoS One239770652013
A02-01
高田礼人
Okamatsu M, et al.The genetic and antigenic diversity of avian influenza viruses isolated from domestic ducks, muscovy ducks, and chickens in northern and southern Vietnam, 2010-2012.Virus Genes238610182013
A02-01
高田礼人
Hoenen T, et al.A novel Ebola virus expressing luciferase allows for rapid and quantitative testing of antivirals.Antiviral Res.237513672013
A02-01
高田礼人
Changula K, et al.Mapping of conserved and species-specific antibody epitopes on the Ebola virus nucleoprotein.Virus Res.237021992013
A02-01
高田礼人
Takada ADo therapeutic antibodies hold the key to an effective treatment for Ebola hemorrhagic fever?Immunotherapy236387382013
A02-04
大戸梅治
Deguchi A, et al.Serum amyloid A3 binds MD-2 to activate p38 and NF-κB pathways in a MyD88-dependent manner.J Immunol.238580302013
A02-04
大戸梅治
Kono N, et al.Impaired α-TTP-PIPs interaction underlies familial vitamin E deficiency.Science235992662013
A02-05
野田岳志
Sugita Y, et al.Configuration of viral ribonucleoprotein complexes within the influenza A virion.J Virol.240679522013
A02-05
野田岳志
Bornholdt ZA, et al.Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle.Cell239531102013
A02-05
野田岳志
Goto H, et al.The genome-packaging signal of the influenza A virus genome comprises a genome incorporation signal and a genome-bundling signal.J Virol.239263452013
A02-05
野田岳志
Watanabe T, et al.Characterization of H7N9 influenza A viruses isolated from humans.Nature238424942013
A02-05
野田岳志
Takahashi K, et al.DNA topoisomerase 1 facilitates the transcription and replication of the Ebola virus genome.J Virol.236584562013
A02-06
加藤哲久
Kato A, et al.Phosphorylation of a herpes simplex virus 1 dUTPase by a viral protein kinase, Us3, dictates viral pathogenicity in the central nervous system but not at the periphery.J Virol.243524672014概要
A02-06
加藤哲久
Fujii H, et al.Role of the nuclease activities encoded by herpes simplex virus 1 UL12 in viral replication and neurovirulence.J Virol.243353052014概要
A02-06
加藤哲久
Koyanagi N, et al.Role of herpes simplex virus 1 Us3 in viral neuroinvasiveness.Microbiol Immunol.242004202013
A02-06
加藤哲久
Kato A, et al.Herpes simplex virus 1 protein kinase Us3 phosphorylates viral dUTPase and regulates its catalytic activity in infected cells.J Virol.241732312014概要
A02-06
加藤哲久
Maruzuru Y, et al.Roles of p53 in herpes simplex virus 1 replication.J Virol.237852012013概要
A02-07
片平正人
Mashima T, et al.Anti-prion activity of an RNA aptamer and its structural basis.Nucleic Acids Res.231807802013
A02-07
片平正人
Kondo K, et al.Structure of perosamine-containing polysaccharide, a component of the sheath of Thiothrix fructosivorans.Int J Biol Macromol.235879982013
A02-08
本田知之
Honda T, et al.Nucleocytoplasmic shuttling of viral proteins in Borna disease virus infection.Viruses239655282013
A02-08
本田知之
Honda T, et al. (Ed. Henderson, B)Host Molecular Chaperones: Cell Surface Receptors for Viruses.Heat Shock Proteins (Moonlighting Cell Stress Proteins in Microbial Infections)2013
A02-09
奥野哲朗
Hyodo K, et al.ADP ribosylation factor 1 plays an essential role in the replication of a plant RNA virus.J Virol.23097452 2013
A02-09
奥野哲朗
Okuno T, et al.Molecular biology and epidemiology of dianthoviruses.Adv Virus Res.238099202013
A02-13
小柴琢己
Sasaki O, et al.A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer.Biochim Biophys Acta.233377712013
A02-14
森川裕子
Sudo S, et al.Efavirenz enhances HIV-1 Gag processing at the plasma membrane through Gag-Pol dimerization.J Virol.233028742013
A02-14
森川裕子
Tomo N, et al.Trans-packaging of human immunodeficiency virus type 1 genome into Gag virus-like particles in Saccharomyces cerevisiae.Microb Cell Fact.235309152013
A02-14
森川裕子
Urano E, et al.Novel role of HSP40/DNAJ in the regulation of HIV-1 replication.J Acquir Immune Defic Syndr.240479682013
A02-14
森川裕子
Ikeno S, et al.Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR.Front Microbiol.241305562013
A02-16
佐藤裕徳
A02-17
俣野哲朗
Burwitz BJ, et al.Tertiary mutations stabilize CD8+ T lymphocyte escape-associated compensatory mutations following transmission of simian immunodeficiency virus.J Virol.243710682014
A02-16
佐藤裕徳
Kudoh A, et al.The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions.Retrovirology244473382014
A02-16
佐藤裕徳
Motozono C, et al.Cross-reactivity analysis of T cell receptors specific for overlapping HIV-1 Nef epitopes of different lengths.Microbes Infect.243807902013
A02-16
佐藤裕徳
Koyama T, et al.APOBEC3G oligomerization is associated with the inhibition of both Alu and LINE-1 retrotransposition.PLoS One243676442013
A02-16
佐藤裕徳
Nomaguchi M, et al.Generation of rhesus macaque-tropic HIV-1 clones that are resistant to major anti-HIV-1 restriction factors.J Virol.239663852013
A02-16
佐藤裕徳
Sato H, et al.Genomics and computational science for virus research.Front Microbiol.234720602013
A02-16
佐藤裕徳
Tsuchiya K, et al.Arginine insertion and loss of N-linked glycosylation site in HIV-1 envelope V3 region confer CXCR4-tropism.Sci Rep.239251522013
A02-16
佐藤裕徳
Yuan Y, et al.Structure and dynamics of the gp120 V3 loop that confers noncompetitive resistance in R5 HIV-1JR-FL to maraviroc.PLoS One238403152013
A02-16
佐藤裕徳
Fujisaki S, et al.Mutations at the monomer-monomer interface away from the active site of influenza B virus neuraminidase reduces susceptibility to neuraminidase inhibitor drugs.J Infect Chemother.235295012013
A02-16
佐藤裕徳
Saito A, et al.TRIM5 genotypes in cynomolgus monkeys primarily influence inter-individual diversity in susceptibility to monkey-tropic human immunodeficiency virus type 1.J Gen Virol.234866712013
A02-16
佐藤裕徳
Kuwata T, et al.Conformational epitope consisting of the V3 and V4 loops as a target for potent and broad neutralization of simian immunodeficiency viruses.J Virol.234684832013
A02-16
佐藤裕徳
Nomaguchi M, et al.Systemic biological analysis of the mutations in two distinct HIV-1mt genomes occurred during replication in macaque cells.Microbes Infect.233847222013
A02-16
佐藤裕徳
Nomaguchi M, et al.Gag-CA Q110D mutation elicits TRIM5-independent enhancement of?HIV-1mt replication in macaque cells.Microbes Infect.231235442013
A02-16
佐藤裕徳
Kamiyama H, et al.CXCR4-tropic, but not CCR5-tropic, human immunodeficiency virus infection is inhibited by the lipid raft-associated factors, acyclic retinoid analogs, and cholera toxin B subunit.AIDS Res Hum Retroviruses228456642013
A02-17
俣野哲朗
Naruse TK, et al.Divergence and diversity of ULBP2 genes in rhesus and cynomolgus macaques.Immunogenetics244690652014
A02-17
俣野哲朗
Iwamoto N, et al.Control of SIV replication by vaccine-induced Gag- and Vif-specific CD8+ T cells.J Virol.241553982014
A02-17
俣野哲朗
Nakane T, et al.Limited impact of passive non-neutralizing antibody immunization in acute SIV infection on viremia control in rhesus macaques.PLoS One240399472013
A02-17
俣野哲朗
Shi S, et al.IL-21-producer CD4+ T cell kinetics during primary simian immunodeficiency virus infection.Microbes Infect.237919542013