Selected Publications

【Original Articles】
Nguyen LTT, Takemura AJ, Ohniwa RL, Saito S, Morikawa K. Sodium Polyanethol Sulfonate Modulates Natural Transformation of SigH-Expressing Staphylococcus aureus. Curr Microbiol 2017. pubmed

Ushijima Y, Ohniwa RL, Morikawa K. Identification of Nucleoid Associated Proteins (NAPs) Under Oxidative Stress in Staphylococcus aureus. BMC Microbiol published October 2017. pubmed

Mizuno K, Mizuno M, Yamauchi M, Takemura AJ, Medrano Romero V, Morikawa K. Adjacent-Possible Ecological Niche: Growth of Lactobacillus Species Co-cultured with Escherichia coli in a Synthetic Minimal Medium. Sci Rep published October 2017. pubmed

Cafini F, Medrano Romero V, Morikawa K. Mechanisms of Horizontal Gene Transfer inStaphylococcus aureus. InTech, Eds: Shymaa Enany and Laura Elise Crotty Alexander. 2017. Book Chapter

Cafini F, Nguyen LTT, Román F, Prieto F, Dubrac S, Msadek T, and Morikawa K. Methodology for The Study of Horizontal Gene Trabsfer in Staphylococcus aureus. JoVE 121 doi:10.3791/55087. 2017.pubmed

Ushijima Y, Yoshida O, Villanueva MJ, Ohniwa RL, Morikawa K. Nucleoid cumping dispensable for the Dps-dependent hydrogen peroxide resistance in Staphylococcus aureus. Microbiol  doi: 10.1099/mic.0.000353. 2016. pubmed

Medrano Romero V, Morikawa K. Liseria monocytogenes σH contributes to expression of competence genes and intercellular growth. J Bacteriol 198:1207-1217.  doi: 10.1128/JB.00718-15. 2016. pubmed

Nguyen LTT, Medrano Romero V, Morikawa K. Cell wall-affecting antibiotics modulate natural transformation in SigH-expressing Staphylococcus aureus. J Antibiot doi: 10. 1038/ja. 132. 2015. pubmed

Cafinii F, Nguyen LTT, Higashide M, Román F, Prieto J, Morikawa K. Horizontal Gene Transmission of cfr gene to MRSA and Enterococcus: role of S. epidermidis as reservoir and alternative pathway for the spread of linezolid resistance. J Antimicrob Chemother. 71 (3):587-92. doi: 10.1093/jac/dkv391.2015. pubmed

Maudsdotter L, Imai S, Ohniwa RL, Saito S, Morikawa K. Staphylococcus aureus dry stress survivors have a heritable fitness advantage in subsequent dry exposure. Microb Infec 17(6):456-61. doi: 10.1016/j.micinf.2015.02.004. 2015. pubmed

Ushijima Y, Ohniwa RL, Morikawa K. In vitro DNA Protection Assay Using Oxidative Stress. Bio-protocol 5:1538. 2015. link

Ushijima Y, Ohniwa RL, Maruyama A, Saito S, Tanaka Y, Morikawa K. Nucleoid compaction by MrgAAsp56Ala/Glu60Ala does not contribute to staphylococcal cell survival against oxidative stress and phagocytic killing by macrophage. FEMS Microbiol Lett 360(2):144-51. doi: 10.1111/1574-6968.12598. 2014. pubmed

Vong LB, Yoshitomi T, Morikawa K, Saito S, Matsui H, Nagasaki Y. Oral nanotherapeutics: Effect of redox nanoparticle on microflora in mice with dextran sodium sulfate-induced colitis. J Gastroenterol 49(5):806-13. doi: 10.1007/s00535-013-0836-8.  2014. pubmed

Ohniwa RL, Muchaku H, Saito S, Wada C, Morikawa K. Atomic force microscopy analysis of the role of major DNA-binding proteins in organization of the nucleoid in Escherichia coli. PLoS One 8(8):e72954. doi: 10.1371/journal.pone.0072954. eCollection. 2013. pubmed

Masami Ueta, Wada C, Daifuku T, Sako Y, Bessho Y, Kitamura A, Ohniwa RL, Morikawa K, Yoshida H, Kato T, Miyata T, Namba K, Wada A. Conservation of two distinct types of 100S ribosomes in bacteria. Genes Cells 118(7):554-74. doi: 10.1111/gtc.12057. 2013. pubmed

Morikawa K, Takemura AJ, Inose Y, Tsai M, Nguyen Thi le T, Ohta T, Msadek T. Expression of a cryptic secondary sigma factor gene unveils natural competence for DNA transformation in Staphylococcus aureus. PLoS Pathog 8(11):e1003003. doi: 10.1371/journal.ppat.1003003. . 2012. pubmed

Ohniwa RL, Kitabayashi K, Morikawa K. Alternative cardiolipin synthase Cls1 compensates for stalled Cls2 function in Staphylococcus aureus under conditions of acute acid stress. FEMS Microbiol Lett 338(2):141-6. doi: 10.1111/1574-6968.12037.  2012. pubmed

Tsai M, Ohniwa RL, Kato Y, Takeshita SL, Ohta T, Saito S, Hayashi H, Morikawa K. Staphylococcus aureus requires cardiolipin for survival under high salinity conditions. BMC Microbiol 11:13. doi: 10.1186/1471-2180-11-13. 2011. pubmed

Ohniwa RL, Ushijima Y, Saito S,Morikawa K. Proteomic Analyses of Nucleoid-Associated Proteins in Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. PLoS ONE 6(4):e19172. doi: 10.1371/journal.pone.0019172. 2011. pubmed

Morikawa K, Ohniwa RL, Ohta T, Tanaka Y, Takeyasu K, Msadek T. Adaptation beyond the Stress Response: Cell Structure Dynamics and Population Heterogeneity in Staphylococcus aureus. Microbes Environ 25(2):75-82. Review. 2010. pubmed


【Proceedings】
Yuri Ushijima and Kazuya Morikawa. E. coli Dps without its DNA binding activity (DpsΔ18) can compensate for S. aureus MrgA in hydrogen peroxide resistance. Microbes in the spotlight: recent progress in the understanding of beneficial and harmful microorganisms. 2016.

Aya J Takemura, Yuri Ushijima, Le Thuy Nguyen Thi, and Kazuya Morikawa. Classical rsbU- strains of S. aureus exhibit better growth in synthetic nasal medium. Microbes in the spotlight: recent progress in the understanding of beneficial and harmful microorganisms. 2016.

Le Thuy T. Nguyen, Kazuya Morikawa. “Effects of Antibiotics on Natural Competence in Staphylococcus aureus”. 16th International Symposium on Staphylococci and Staphylococcal Infections. 2014.

Le Thuy Nguyen Thi, Aya J Takemura, Yumiko Inose, Melody Tsai, Toshiko Ohta, Tarek Msadek, and Kazuya Morikawa. First evidences of genetic transformation via natural competence in Staphylococcus aureus. J Bacteriol Parasitol. 114(4): ISSN: 2155-9597 doi: 10.4172/2155-9597.S1.003. 2013.