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2017”N
Kajitani K, Kato K, Nagata K.
Histone H1 chaperone activity of TAF-I is regulated by its subtype-dependent intramolecular interaction.
Genes to Cells In press. 2017 Apr. doi:10.1111/gtc.12478.
2016”N
Sekiya T, Murano K, Kato K, Kawaguchi A, Nagata K.
Mitotic phsphorylation of CCCTC-binding factor (CTCF) reduces its DNA binding activity.
FEBS Open Bio. 2017 Mar. doi:10.1002/2211-5463.12189
Minakuchi M, Sugiyama K, Kato Y, Naito T, Okuwaki M, Kawaguchi A, Nagata K.
Pre-mRNA processing factor Prp18 is a stimulatory factor of influenza virus RNA synthesis and possesses the NP chaperone activity.
Journal of Virology 2016 Nov 16. doi:10.1128/JVI.01398-16.
Jianhuang Lin, Mitsuyasu Kato, Kyosuke Nagata, Mitsuru Okuwaki.
Efficient DNA binding of NF-kB requires the chaperone-like function of NPM1.
Nucleic Acids Research. 2016 Dec. doi: 10.1093/nar/gkw1285
Jianhuang Lin, Miharu Hisaoka, Kyosuke Nagata, Mitsuru Okuwaki.
Functional characterization and efficient detection of Nucleophosmin/NPM1 oligomers.
Biochemical and biophysical research communications, Nov 25; 480 (4): 702-708. doi: 10.1016/j.bbrc.2016.10.125
Kenji Sugiyama, Nagata K.
Purification and Identification of Novel Host-derived Factors for Influenza Virus Replication from Human Nuclear Extracts.
Bio-protocol, 2016; 6: e1934. (http://www.bio-protocol.org/e1934)
Cigdem S ,Saito S, Nagata K.
Aberrant nuclear-cytoplasmic transport by leukemia-associated Nup214-fusion proteins.
FEBS J. 2016 Sep 07; 283, Suppl. 1; ST-05.02.2.009. DOI:10.1111/febs.13807
Okuwaki M., Abe M., Hisaoka M., Nagata K.
Regulation of Cellular Dynamics and Chromosomal Binding Site Preference of linker Histones H1.0 and H1.X.
Mol. Cell. Biol. 2016 Oct 13; 36(21):2681-2696. doi: 10.1128/MCB.00200-16
Asaka MN, Kawaguchi A, Sakai Y, Mori K, Nagata K.
Polycomb repressive complex 2 facilitates the nuclear export of the influenza viral genome through the interaction with M1.
Scientific Reports 2016 Sep 20; 6:33608. doi: 10.1038/srep33608.
Saito S, Cigdem S, Okuwaki M, Nagata K. (equally contributed)
Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-ƒÈB Signaling Pathway.
Mol Cell Biol. 2016 Jun 15; 36(13):1820-35. doi: 10.1128/MCB.00158-16. Print 2016 Jul 1.
2015”N
Kawaguchi A, Hirohama M,Harada Y, Osari S, Nagata K.
Influenza Virus Induces Cholesterol-Enriched Endocytic Recycling Compartments for Budozone Formation via Cell Cycle-Independent Centrosome Maturation.
PLoS Pathog. November 17, 2015DOI: 10.1371/journal.ppat.1005284
Sugiyama K, Kawaguchi A, Okuwaki M, Nagata K.
pp32 and APRIL are host cell-derived regulators of influenza virus RNA synthesis from cRNA.
Elife. 2015 Oct 29;4. pii: e08939. doi: 10.7554/eLife.08939. [Epub ahead of print]
Nishie T, Nagata K.
Measles virus C protein facilitates transcription by the control of N protein-viral genomic RNA interaction in early phases of infection.
Biochem Biophys Res Commun. 2015 Aug 7;463(4):1262-6.
Mori K, Murano K, Ohniwa RL, Kawaguchi A, Nagata K.
Oseltamivir Expands Quasispecies of Influenza Virus through Cell-to-cell Transmission.
Sci Rep. 2015 Mar 16;5:9163.
Kawaguchi A, Asaka MN, Matsumoto K, Nagata K.
Centrosome maturation requires YB-1 to regulate dynamic instability of microtubules for nucleus reassembly.
Sci Rep. 2015 Mar 5;5:8768.
Inoue-Toyoda M, Kato K, Nagata K, Yoshikawa H.
Glucocorticoids facilitate the transcription from the human cytomegalovirus major immediate early promoter in glucocorticoid receptor- and nuclear factor-I-like protein-dependent manner.
Biochem Biophys Res Commun. 2015 Feb 27;458(1):180-5.
2014”N
Kumakura M, Kawaguchi A, Nagata K.
Actin-myosin network is required for proper assembly of influenza virus particles.
Virology. 2014 Dec 24;476C:141-150.
Nemeth E, Kortvelyesi T, Kozisek M, Thulstrup PW, Christensen HE, Asaka MN, Nagata K, Gyurcsik B.
Substrate binding activates the designed triple mutant of the colicin E7 metallonuclease.
J Biol Inorg Chem. 2014 Dec;19(8):1295-303.
Czene A, Toth E, Nemeth E, Otten H, Poulsen JC, Christensen HE, Rulisek L, Nagata K, Larsen S, Gyurcsik B.
A new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational study.
Metallomics. 2014 Oct 22;6(11):2090-9.
Nemeth E, Kortvelyesi T, Thulstrup PW, Christensen HE, Kozisek M, Nagata K, Czene A, Gyurcsik B.
Fine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N-terminal mutations.
Protein Sci. 2014 Aug;23(8):1113-22.
Murano K, Okuwaki M, Momose F, Kumakura M, Ueshima S, Newbold RF, Nagata K.
Reconstitution of human rRNA gene transcription in mouse cells by a complete SL1 complex.
J Cell Sci. 2014 Aug 1;127(Pt 15):3309-19.
Kadota S, Nagata K.
Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I.
Nucleic Acids Res. 2014;42(12):7642-53.
Hisaoka M, Nagata K, Okuwaki M.
Intrinsically disordered regions of nucleophosmin/B23 regulate its RNA binding activity through their inter- and intra-molecular association.
Nucleic Acids Res. 2014 Jan;42(2):1180-95
Binh NT, Wakai C, Kawaguchi A, Nagata K.
Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition.
Biochem Biophys Res Commun. 2014 Jan 17;443(3):975-9.
Ueshima S, Nagata K, Okuwaki M.
Upstream binding factor-dependent and pre-rRNA transcription-independent association of pre-rRNA processing factors with rRNA gene.
Biochem Biophys Res Commun. 2014 Jan 3;443(1):22-7.
2013”N
Binh NT, Wakai C, Kawaguchi A, Nagata K.
The N-terminal region of influenza virus polymerase PB1 adjacent to the PA binding site is involved in replication but not transcription of the viral genome.
Front Microbiol. 2013 Dec 18;4:398.
Czene A, Toth E, Gyurcsik B, Otten H, Poulsen JC, Lo Leggio L, Larsen S, Christensen HE, Nagata K.
Crystallization and preliminary crystallographic analysis of an Escherichia coli-selected mutant of the nuclease domain of the metallonuclease colicin E7.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1;69(Pt 5):551-4.
Tetsuro Komatsu, Takeshi Sekiya, Nagata Kyosuke.
DNA replication-dependent binding of CTCF plays a critical role in adenovirus genome functions.
Sci Rep. 2013 July 15. Article number: 2187.
Czene A, Nemeth E, Zoka IG, Jakab-Simon NI, Kortvelyesi T, Nagata K, Christensen HE, Gyurcsik B.
The role of the N-terminal loop in the function of the colicin E7 nuclease domain.
J Biol Inorg Chem. 2013 Mar;18(3):309-21.
2012”N
Haruyama T, Nagata K.
Anti-influenza virus activity of Ginkgo biloba leaf extracts.
J Nat Med. 2012 Nov 22. [Epub ahead of print]
Kawaguchi A, Matsumoto K, Nagata K.
YB-1 functions as a porter to lead influenza virus ribonucleoprotein complexes to microtubules.
J Virol. 2012 Oct;86(20):11086-95. Epub 2012 Aug 1.
Komatsu T, Nagata K.
Replication-uncoupled histone deposition during adenovirus DNA replication.
J Virol. 2012 Jun;86(12):6701-11. doi: 10.1128/JVI.00380-12. Epub 2012 Apr 11.
Okuwaki M, Sumi A, Hisaoka M, Saotome-Nakamura A, Akashi S, Nishimura Y, Nagata K.
Function of homo- and hetero-oligomers of human nucleoplasmin/nucleophosmin family proteins NPM1, NPM2 and NPM3 during sperm chromatin remodeling.
Nucleic Acids Res. 2012 Jun;40(11):4861-78. doi: 10.1093/nar/gks162. Epub 2012 Feb 22.
Samad MA, Komatsu T, Okuwaki M, Nagata K.
B23/nucleophosmin is involved in regulation of adenovirus chromatin structure at late infection stages, but not in virus replication and transcription.
J Gen Virol. 2012 Jun;93(Pt 6):1328-38. doi: 10.1099/vir.0.036665-0. Epub 2012 Feb 15.
2011”N
Mori K, Haruyama T, Nagata K.
Tamiflu-resistant but HA-mediated cell-to-cell transmission through apical membranes of cell-associated influenza viruses.
PLoS One. 2011;6(11):e28178. doi: 10.1371/journal.pone.0028178. Epub 2011 Nov 30.
Numajiri Haruki A, Naito T, Nishie T, Saito S, Nagata K.
Interferon-inducible antiviral protein MxA enhances cell death triggered by endoplasmic reticulum stress.
J Interferon Cytokine Res. 2011 Nov;31(11):847-56. doi: 10.1089/jir.2010.0132. Epub 2011 Oct 12.
Kato K, Okuwaki M, Nagata K.
Role of Template Activating Factor-I as a chaperone in linker histone dynamics.
J Cell Sci. 2011 Oct 1;124(Pt 19):3254-65. doi: 10.1242/jcs.083139.
Numata M, Nagata K.
Synergistic requirement of orphan nonamer-like elements and DNA bending enhanced by HMGB1 for RAG-mediated nicking at cryptic 12-RSS but not authentic 12-RSS.
Genes Cells. 2011 Aug;16(8):879-95. doi: 10.1111/j.1365-2443.2011.01534.x. Epub 2011 Jul 11.
Wakai C, Iwama M, Mizumoto K, Nagata K.
Recognition of cap structure by influenza B virus RNA polymerase is less dependent on the methyl residue than recognition by influenza A virus polymerase.
J Virol. 2011 Aug;85(15):7504-12. doi: 10.1128/JVI.02375-10. Epub 2011 May 18.
Kawaguchi A, Momose F, Nagata K.
Replication-coupled and host factor-mediated encapsidation of the influenza virus genome by viral nucleoprotein.
J Virol. 2011 Jul;85(13):6197-204. doi: 10.1128/JVI.00277-11. Epub 2011 Apr 20.
Kadota S, Nagata K.
pp32, an INHAT component, is a transcription machinery recruiter for maximal induction of IFN-stimulated genes.
J Cell Sci. 2011 Mar 15;124(Pt 6):892-9. doi: 10.1242/jcs.078253. Epub 2011 Feb 15.
2010”N
Numata M, Saito S, Nagata K.
RAG-dependent recombination at cryptic RSSs within TEL-AML1 t(12;21)(p13;q22) chromosomal translocation region.
Biochem Biophys Res Commun. 2010 Nov 26;402(4):718-24.
Komatsu T, Haruki H, Nagata K.
Cellular and viral chromatin proteins are positive factors in the regulation of adenovirus gene expression.
Nucleic Acids Res. 2011 Feb;39(3):889-901.
Hisaoka M, Ueshima S, Murano K, Nagata K, Okuwaki M.
Regulation of nucleolar chromatin by B23/nucleophosmin jointly depends upon its RNA binding activity and transcription factor UBF.
Mol Cell Biol. 2010 Oct;30(20):4952-64.
Jo S, Kawaguchi A, Takizawa N, Morikawa Y, Momose F, Nagata K.
Involvement of vesicular trafficking system in membrane targeting of the progeny influenza virus genome.
Microbes Infect. 2010 Nov;12(12-13):1079-84.
Okuwaki M, Kato K, Nagata K.
Functional characterization of human nucleosome assembly protein 1-like proteins as histone chaperones.
Genes Cells. 2010 Jan;15(1):13-27.
2009”N
Ninomiya K, Kanayama T, Fujieda N, Nakayama T, Komase K, Nagata K, Takeuchi K.
Amino acid substitution at position 464 in the haemagglutinin-neuraminidase protein of a mumps virus Urabe strain enhanced the virus growth in neuroblastoma SH-SY5Y cells.
Vaccine. 2009 Oct 19;27(44):6160-5.
Okada H, Itoh M, Nagata K, Takeuchi K.
Previously unrecognized amino acid substitutions in the hemagglutinin and fusion proteins of measles virus modulate cell-cell fusion, hemadsorption, virus growth, and penetration rate.
J Virol. 2009 Sep;83(17):8713-21.
Sugiyama K, Obayashi E, Kawaguchi A, Suzuki Y, Tame JR, Nagata K, Park SY.
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase.
EMBO J. 2009 Jun 17;28(12):1803-11.
2008”N
Asaka MN, Murano K, Nagata K.
Sp1-mediated transcription regulation of TAF-Ialpha gene encoding a histone chaperone.
Biochem Biophys Res Commun. 2008 Nov 28;376(4):665-70.
Komaki-Yasuda K, Okuwaki M, Kano S, Nagata K, Kawazu S.
5' sequence- and chromatin modification-dependent gene expression in Plasmodium falciparum erythrocytic stage.
Mol Biochem Parasitol. 2008 Nov;162(1):40-51.
Obayashi E, Yoshida H, Kawai F, Shibayama N, Kawaguchi A, Nagata K, Tame JR, Park SY.
The structural basis for an essential subunit interaction in influenza virus RNA polymerase.
Nature. 2008 Aug 28;454(7208):1127-31.
Murayama A, Ohmori K, Fujimura A, Minami H, Yasuzawa-Tanaka K, Kuroda T, Oie S, Daitoku H, Okuwaki M, Nagata K, Fukamizu A, Kimura K, Shimizu T, Yanagisawa J.
Epigenetic control of rDNA loci in response to intracellular energy status.
Cell. 2008 May 16;133(4):627-39.
Murano K, Okuwaki M, Hisaoka M, Nagata K.
Transcription regulation of the rRNA gene by a multifunctional nucleolar protein, B23/nucleophosmin, through its histone chaperone activity.
Mol Cell Biol. 2008 May;28(10):3114-26.
Saito S, Nouno K, Shimizu R, Yamamoto M, Nagata K.
Impairment of erythroid and megakaryocytic differentiation by a leukemia-associated and t(9;9)-derived fusion gene product, SET/TAF-Ibeta-CAN/Nup214.
J Cell Physiol. 2008 Feb;214(2):322-33.
2007”N
Naito T, Kiyasu Y, Sugiyama K, Kimura A, Nakano R, Matsukage A, Nagata K.
An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for viral RNA synthesis.
Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18235-40.
Kawaguchi A, Nagata K.
De novo replication of the influenza virus RNA genome is regulated by DNA replicative helicase, MCM.
EMBO J. 2007 Oct 31;26(21):4566-75.
Samad MA, Okuwaki M, Haruki H, Nagata K.
Physical and functional interaction between a nucleolar protein nucleophosmin/B23 and adenovirus basic core proteins.
FEBS Lett. 2007 Jul 10;581(17):3283-8.
Nishie T, Nagata K, Takeuchi K..
The C protein of wild-type measles virus has the ability to shuttle between the nucleus and the cytoplasm.
Microbes Infect. 2007 Mar;9(3):344-54.
Kato K, Miyaji-Yamaguchi M, Okuwaki M, Nagata K.
Histone acetylation-independent transcription stimulation by a histone chaperone.
Nucleic Acids Res. 2007;35(3):705-15.
Naito T, Momose F, Kawaguchi A, Nagata K.
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits.
J Virol. 2007 Feb;81(3):1339-49.

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