University of Tsukuba (Institute of Basic Medical Sciences, University of Tsukuba ) Molecular Virology, Field of Infection Biology Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences

Associate Professor

PhD (Kyoto University)

Virology

Study on replication and phathogenesity of measles and influenza virus
Development of virus vectors and oncolytic viruses

-The Japanese Society for Virology
-The Molecular biology Society of Japan
-The Japanese Society for Clinical Virology

Takeda M, Takeuchi K , Miyajima N, Kobune F, Ami Y, Nagata N, Suzaki Y, Nagai Y and Tashiro M, Recovery of pathogenic measles virus from cloned cDNA. J Virol 2000;74:6643-6647.

Takeuchi K , Takeda, M, Miyajima N, Kobune F, Tanabayashi K and Tashiro M, Recombinant wild-type and Edmonston strain measles viruses bearing heterologous H proteins: role of H protein in cell fusion and host cell specificity. J Virol 2002;76:4891-4900.

Takeuchi K , Miyajima N, Nagata N, Takeda M and Tashiro M. Wild-type measles virus induces large syncytium formation in primary human airway epithelial cells by a SLAM(CD150)-independent mechanism. Virus Res 2003;94:11-16.

Takeuchi K , Kadota S, Takeda M, Miyajima N and Nagata K. Measles virus V protein blocks interferon- a / b but not interferon- g signaling by inhibiting STAT1 and STAT2 phosphorylation. FEBS Lett 2003;545:177-182.

Miyajima N, Takeda M, Tashiro M, Hashimoto K, Yanagi Y, Nagata K, and Takeuchi K . Cell tropism of wild-type measles virus is affected by amino acid substitutions in the P, V and M proteins, or by a truncation in the C protein. J Gen Virol 2004 (in press).

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