シラバス Syllabus Doctoral Program in Biomedical Sciences
科目名・科目番号
Subjects・Course Number
02EW401 /   Lecture and Discussion in Molecular Medical Sciences I  02EW403  / Seminar in Molecular Medical Sciences Ⅰ 02EW405  / Practice  in Molecular Medical Sciences I
02EW402 / Lecture and Discussion in Molecular Medical Sciences II 02EW404  / Seminar in Molecular Medical Sciences II 02EW406 / Practice  in Molecular Medical Sciences Ⅱ
研究分野
Laboratories
Molecular and Developmental Biology Molecular and Developmental Biology Molecular and Developmental Biology
使用言語
Language used (Japanese,  English,  Bilingual)
Japanese or English (Slide & print are in English) Japanese or English (Slide & print are in English) Japanese or English
他研究室学生の受け入れの可否(〇×)
Availability for students from other lab.
○ possible ○ possible TBD upon request.
他研究室学生の問い合わせ先
Contact Information for Students from Other  Lab.
KOBAYASHI Makoto: makobayash at画像 KOBAYASHI Makoto: makobayash at画像 KOBAYASHI Makoto: makobayash at画像
授業形態
Course Type
Lecture, presentation and discussion Seminar Practice 
標準履修年次
Year
1 or 2 1 or 2 1 or 2
実施学期・曜時限等
Semester, Day and Period
ⅠSpring semester / ⅡAutumn semester ⅠSpring semester / ⅡAutumn semester ⅠSpring semester / ⅡAutumn semester
開講場所
Room Number
     
単位数
Credit
Spring and Autumn semester, 2 x 2 credits Spring and Autumn semester, 2 x 2 credits Spring and Autumn semester, 2 x 2 credits
担当教員名・オフィスアワー等 (make an appointment by E-mail) (make an appointment by E-mail) (make an appointment by E-mail)
Faculty Members and E-mail KOBAYASHI Makoto: makobayash at画像 KOBAYASHI Makoto: makobayash at画像 KOBAYASHI Makoto: makobayash at画像
授業概要
Course overview
Students learn skills to design and perform experiments, and evaluate the experimental results through discussing your own results concerning the mechanisms underlying the formation of hematopoietic stem cells and digestive organs, antioxidant mechanism of functional food ingredients and human disease models. This is a literature-based, seminar-type course. Students will acquire skills to understand the purpose, methods, and results of latest articles related to Molecular and Developmental Biology and discuss the significances, problems, and future directions of the study. In this course, students will practically learn methods, experimental principles, and safe handling techniques required for the research in Molecular and Developmental Biology.
授業の到達目標(学修成果)
Course Objectives (Learning Outcomes)
←SBO(Specific Behavior Objectives
1. To be able to give a presentation about your own research objectives, methods, results, and future directions.
2. To be able to explain originality and creativity of your own research project.
3. To be able to accept criticisms from other participants to improve your own research project.
4. To be able to understand the presentations of other speakers, and provide constructive criticism.
5. To be able to design and perform experiments of recombinant DNA according to the Act concerning recombinant DNA experiment.
6. To be able to design and perform the animal experiments according to the bioethical rule.
7. To build abilities to present and publish your own experimental results.
1. To develop an ability to select important articles from latest ones by using online search service.
2. To develop an ability to introduce research topics to a general audience in time given.
3. To be able to discuss the unclear points and significances of the articles which are explained by other participants.
4. To develop an ability to evaluate the significance of the selected articles in the related field of research.
1. To be able to understand the basis of animal experiments and to perform the generation of gene recombinant zebrafish, genotyping, microscope observation, and so on.
2. To be able to understand the basis of molecular biology and to construct recombinant genes according to the Act concerning recombinant DNA experiment.
3. To be able to understand the basis of molecular and developmental biology and to perform gene expression analysis, gene function analysis,, chemical biology experiments, imaging analysis, and so on. 
キーワード
Keyword
Gene expression, epigenetics, zebrafish, hematopoiesis, organogenesis, antioxidants, food phytochemicals, human disease model Gene expression, epigenetics, zebrafish, hematopoiesis, organogenesis, antioxidants, food phytochemicals, human disease model Gene expression, epigenetics, zebrafish, hematopoiesis, organogenesis, antioxidants, food phytochemicals, human disease model
授業計画
Course Schedule

第1回(月日、時限)担当教員名 講義内容など
Weekly, Tuesday 17:00-
Through lecture and discussion series, students acquire knowledge and creativity to set proper research objective, select appropriate methodology,  understand the significance of results, and to further design following experiments independently, concerning Molecular and Developmental Biology. In additions, students also learn and confirm general knowledge underlying each specific subjects.
Weekly, Friday 17:00-
Class meets every week. Topics to be discussed will be selected by students. Points to be learned include:
How to select papers.
Historical background and creativity of good scientific papers.
Structure of scientific papers.
How to interpretate the results.
Logical flow in scientific papers.
Class meets every week.
1. Zebrafish genetics and animal experiments
2. Recombinant DNA experiments
3. Gene expression analysis
4. Gene function analyses
5. Chemical biology experiments
6. Imaging analysis
履修条件
Course prerequisite
None None None
成績評価方法
Grading Criteria
Students are evaluated by the achievement of the objectives listed in the SBO.
- Good achieved under supervision in the SBOs 1 and 2:  Pass (C).
- Good achieved under supervision in the SBOs 1 - 3, and actively conducted SBO 4:  Pass (B).
SBOs 1 - 3 will be evaluated based on a brief report in terms of presentation and discussion.
- Excellent achievement in SBOs 1-4, and good achievement in SBOs 5-7: (A)
- Outstanding achievement with enough evidence in all SBOs : Pass (A+)
Students are evaluated by the achievement of the objectives listed in the SBO.
- Good achieved  in the SBOs 1 and 2:  Pass (C).
- Good achieved in the SBOs 1 - 2, and actively conducted SBO 3:  Pass (B).
Based on written summary of papers (A4 1 page, twice a month).  good achievement including SBO 4 is confirmed,: Pass (A).
- Outstanding achievement with enough evidence in all SBOs : Pass (A+)
Skills to obtain reliable experimental results (50%)
Understanding of results, and ability to design next experiments will be evaluated by experimental notebook and discussion (50%)
A+: Superior (more than 90: top 10%)
A: Excellent (80-89: upper 20%)
B: Good (70-79)
C: Average (60-69)
D: Failure (less than 60)
学修時間の割り当て及び授業外における学修方法
Learning method
Lecture 100% Training (Seminar) 100% Experiment, Practice 100%
教材・参考文献
Textbook
Handouts prepared by presenters Handouts prepared by presenters Basic protocols for experiments will be provided.
単位取得要件
Requirement to earn credit
Requirement to earn credit: Attendance 80% or more.
Attendance of 5 hours or more to other lab's classes.
Requirement to earn credit: Attendance 80% or more.
Attendance of 5 hours or more to other lab's classes.
Requirement to earn credit: Attendance 80% or more.
その他(受講上の注意点等)
Notes
Students from Molecular and Developmental Biology lab have to attend the course of Practice in Molecular and Developmental Biology.
Students should resolve the questions immediately.
Students should thoroughly discuss scientifically, logically, and properly.
Students should resolve the questions immediately.
Students should thoroughly discuss scientifically, logically, and properly.
Students should contact a responsible faculty member, and get permission beforehand.
Students should resolve the questions immediately.
他の授業科目との関連
Relation to Other Courses
Seminar in Molecular Medical Sciences I, II
Practice  in Molecular Medical Sciences I, II
Lecture and Discussion in Molecular Medical Sciences I, II
Practice  in Molecular Medical Sciences I, II
Lecture and Discussion in Molecular Medical Sciences I, II
Seminar in Molecular Medical Sciences I, II

 

「@」は画像です。 "@" is an image file.