シラバス Syllabus	Doctoral Program in Biomedical Sciences
科目名・科目番号 Subjects・Course Number	02EW411 /   Lecture and Discussion in Human Medical Biology I	02EW413  / Seminar in Human Medical Biology	02EW415  / Practice  in Human Medical Biology I
	02EW412 / Lecture and Discussion in Human Medical Biology II	02EW414  / Seminar in Human Medical Biology II	02EW416　/ Practice  in Human Medical Biology Ⅱ
研究分野 Laboratories	Neurophysiology	Neurophysiology	Neurophysiology
使用言語 Language used （Japanese,  English,  Bilingual）	English	English	English
他研究室学生の受け入れの可否（〇×） Availability for students from other lab.	○ possible	○ possible	TBD upon request.
他研究室学生の問い合わせ先 Contact Information for Students from Other  Lab.	t-kogane	t-kogane	t-kogane
授業形態 Course Type	Lecture, presentation and discussion	Seminar	Practice
標準履修年次 Year	1 or 2	1 or 2	1 or 2
実施学期・曜時限等 Semester,Day and Period	ⅠSpring semester / ⅡAutumn semester	ⅠSpring semester / ⅡAutumn semester	ⅠSpring semester / ⅡAutumn semester
開講場所 Room Number	Institute of Medicine, Room 462 or other	Institute of Medicine, Room 462 or other	Institute of Medicine, Room 460 or other
単位数 Credit	Spring and Autumn semester, 2 x 2 credits	Spring and Autumn semester, 2 x 2 credits	Spring and Autumn semester, 2 x 2 credits
担当教員名・オフィスアワー等	（make an appointment by E-mail）	（make an appointment by E-mail）	（make an appointment by E-mail）
Faculty Members and E-mail	KOGANEZAWA Tadachika: t-kogane	KOGANEZAWA Tadachika: t-kogane	KOGANEZAWA Tadachika: t-kogane
授業概要 Course overview	This subject is to establish the ability to plan, practice and evaluate the experimental brain research through the presentations and discussion on the research results currently being obtained in our laboratory. Research results using techniques in electrophysiology and pharmacology will be included.	This subject offers the seminar reading recently published papers in neurophysiology. Discussion on the aims and objectives, materials and methods, results, significance, problems of the work will carry out and free talks on the remained research topics to be solved in the field will be done.	To understand the experimental principles and methods required for the research in neural regulation of cardiovascular and respiratory systems. Students will acquire the ability to carry out the experiments with reproducibility and to evaluate the reliability of experimental results.
授業の到達目標（学修成果） Course Objectives (Learning Outcomes) ←SBO(Specific Behavior Objectives	1．To be able to give a presentation about your own research objectives, methods, results, and future directions. 2．To be able to explain originality and creativity of your own research project. 3．To be able to accept criticisms from other participants to improve your own research project. 4．To be able to understand the presentations of other speakers, and provide constructive criticism. 5．To be able to design and perform the animal experiments according to the bioethical rule.	1． To develop an ability to select important articles from latest ones by using online search service. 2． To develop an ability to introduce research topics to a general audience in time given. 3． To be able to discuss the unclear points and significances of the articles which are explained by other paticipants. 4． To develop an ability to evaluatethe significance of the selected articles in the related field of research.	1. To be able to handle animals which used in experiments. 2. To be able to understand the basic principle of anesthesia and do anesthetic management. 3. To be able to understand the basic principle of measurement of blood pressure, perform experiments, and analyze the data. 4. To be able to understand the basic principle of measurement of ECG, perform experiments, and analyze heart rate variability. 5. To be able to understand the basic principle of nerve recording, perform experiments, and analyze the data. 6. To be able to understand the basic principle of single unit recording, perform experiments, and analyze the data 7. To be able to understand the basic principles of electrical stimulation of neurons and nerves, perform experiments, and analyze the data based on the stimulation. 8. To be able to perform understand the basic principle of microinjection of drugs into a brain, and perform experiment
キーワード Keyword	neuroscience, circulation, respiration	neuroscience, circulation, respiration	neuroscience, circulation, respiration
授業計画 Course Schedule 第1回（月日、時限）担当教員名　講義内容など	Mechanism of hemodynamics, cell physiology and neural network which is related with neural regulation of cardiovascular and respiratory systems will be studied. Research presentation and discussion will improve creativity and independency to make students possible to set up research aims and objectives, select research materials and methods, evaluate reliability and significance of the results, and how to select the next step experiment. Students are expected to remained basic general knowledge during the detailed discussion.	Topics to be discussed will be selected by students. Points to be learned include: How to select papers. Histrical background and creativity of good scientific papers. Structure of scientific papers. How to interpretate the results. Logical flow in scientific papers.	1. Handling of experimental animals 2. Anesthesia management 3. Blood pressure recording 4. ECG recording 5. Nerve recording 6. Single unit recording 7. Electrical stimulation 8. Microinjection
履修条件 Course prerequisite	None	None	None
成績評価方法 Grading Criteria	・General achievements in SBO 1-2 will be evaluated to pass (C or upper). ・General achievements in SBO 1-3 and active participation in SBO 4 will be evaluated as B or upper. ・Excellent achievements in SBO 1-4 and achievement in SBO 5 with supervisors’ instruction will be evaluated as A or upper. ・Very excellent achievements in SBO 1-4 and achievement in SBO 5 with supervisors’ instruction will be evaluated as A+.	・General achievements in SBO 1-2 with supervisors’ instructions will be evaluated to pass (C or upper). ・General achievements in SBO 1-2 with supervisors’ instructions, active participation in SBO 3 will be evaluated as B or upper. ・Excellent achievements in SBO 1-4 will be evaluated as A or upper. ・Very excellent achievements in SBO 1-4 will be evaluated as A+.	Skills to obtain reliable experimental results （50%） Understanding of results, and ability to design next experiments will be evaluated by experimental notebook and discussion （50%） A+: Superior (more than 90: top 10%) A: Excellent (80-89: upper 20%) B: Good (70-79) C: Average (60-69) D: Failure (less than 60)
学修時間の割り当て及び授業外における学修方法 Learning method	Lecture 100% The students should always aware of the issues on the contents of the lectures or their own research projects. They also should discuss on the issues each other to improve own creativity and autonomy.	Training (Seminar) 100% Read the paper about own research field and extract problem points.	Experiment, Practice 100% Learned experiments must be repeated by the students, and establish stable and reliable technique.
教材・参考文献 Textbook	TBA	PDF files of the original paper will be sent to the attendants.	The protocol of each experiments will be provided.
単位取得要件 Requirement to earn credit	Requirement to earn credit: Attendance 80％ or more. Attendance of 5 hours or more to other lab's classes.	Requirement to earn credit: Attendance 80％ or more. Attendance of 5 hours or more to other lab's classes.	Requirement to earn credit: Attendance 80％ or more.
その他（受講上の注意点等） Notes	Students take this course with the Seminar and Practice in Neurophysiology. Questions must be asked outright. Try to make rigorous, scientific and logical discussion.	Questions must be asked outright. Try to make rigorous, scientific and logical discussion	We accept registration by the students who select neurophysiology for their research field Registration must be done after approval of the responsible faculty. Questions must be asked outright.
他の授業科目との関連 Relation to Other Courses	Seminar in Human Medical Biology I, II Practice  in Human Medical Biology I, II	Lecture and Discussion in Human Medical Biology I, II Practice  in Human Medical Biology I, II	Lecture and Discussion in Human Medical Biology I, II Seminar in Human Medical Biology I, II

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