Subjects・Course Number
Laboratories
Language used （Japanese, English, Bilingual）
Availability for students from other lab.
Contact Information for Students from Other Lab.
Course Type
Year
Semester,Day and Period
Room Number
Credit
chubyoin.pref.ibaraki.jpchubyoin.pref.ibaraki.jpchubyoin.pref.ibaraki.jpCourse overview
Course Objectives (Learning Outcomes)
←SBO(Specific Behavior Objectives
GIO is for the student to develop abilities of independently planning and conducting research on medical oncology, and of evaluating the results. To accomplish these aims, the students learn techniques on molecular biology, cell biology, animal experiments, histopathology, genetic analysis, and clinical study. The research results obtained and presented by students shall be used for discussion on the pathogenesis of malignant diseases and the development of new therapeutics.
Specific Behavior Objectives (SBO)
1. To be able to present the purpose, methods, results and significance of the students' own research, and to plan future research.
2. To be able to understand the questions and comments on the students' own presentation, to properly answer to them and make a discussion, and to reflect the content of discussions on improving the quality of research.
3. To be able to understand the content of other students' presentations and further their significance and shortcomings, and to ask questions and debates to help improve them.
4. To be able to understand research methods related to molecular biology experiments, and to plan, complete a document on, and implement the experiments appropriately.
5. To be able to understand the regulations on animal experiments, and to plan, complete a document on, and implement animal experiments appropriately.
6. To be able to understand the regulations and bioethical issues on human genome research, and to plan, complete a document on, and implement human genome research.
GIO is for the students to understand the content of the original English papers. Thgough reading those, the students will understand standards of leading research on medical oncology, grasp the research trends in the world, and plan their own unique and valuable research projects .
Specific Behavior Objectives (SBO)
１. To be able to select one or a few papers for reading from the latest original papers using the on-line search system.
２. To be able to read and understand the selected papers, explain the outline to other students within a specified time, and answer questions from other students.
３. To be able to read the paper(s) selected by other students in advance, understand the content, ask questions, and discuss the significance of the study after listening to the explanation by the presenter.
４. To be able to explain the historical significance of each original article.
GIO is for the students to lay the foundation to become those who intend to develop and improve medical oncology research. To achieve this, the students need to actively plan and conduct research on their own, after learning methods on molecular and cell biological experiments, animal experiments, histopathological analysis, and clinical study that underly medical oncology research.
Specific Behavior Objectives (SBO)
１．To be able to learn the basics of research techniques such as molecular and cell biological experiments, animal experiments, histopathological analysis, and clinical research. Specific techniques include, cell culture, PCR, DNA and RNA sequencing (including next generation sequencing) and analysis, Western blotting, flow cytometry, immunohistological staining, disease model mouse analysis, statistical analysis, etc.
２．To be able to make a research plan for each theme and execute it.
３．To beable to assess the creativity and significance of your research plan and results in the relevant field, and reflect it in your next plan.
４．To be able to report the progresses on the findings and the significance within the study group once a week, and to make a debate on other students' reports.
５．To beb able to make presentations at academic societies in the field.
Keyword
Course Schedule
第1回（月日、時限）担当教員名 講義内容など
Students will present their research objectives, methods, results and their significance, and future research to be conducted, take questions and comments, and respond to them in the assigned class. Other students understand the content of the presentation, including its significance and shortcomings, and ask questions and debates to improve it.
Assign students in order for the selection of an original paper and the explanation of its content. The assigned students should report in advance the selected paper and read and understood before the class. In class, the outline will be explained to the instructor and other students within the specified time, and questions will be answered. Students who are not assigned will read the paper in advance and discuss any questions and the significance of the study. The debate includes the historical significance of the original article.
After setting the research theme, students will learn the basics of the research method, focusing on those related to their own research theme. Students will perform experiments based on their own experimental plans, and present and discuss the results. Based on these results and discussions, a subsequent experiment plan is drawn up, and the cycle of performing experiments, presenting the results, and making discussions is repeated.
Course prerequisite
Grading Criteria
- Good achieved under supervision in the SBOs 1 and 2: Pass (C).
- Good achieved under supervision in the SBOs 1 - 3, and actively conducted SBO 4: Pass (B).
SBOs 1 - 3 will be evaluated based on a brief report in terms of presentation and dicsussion.
- Excellent achievement in SBOs 1-4, and good achievement in SBOs 5-7: (A)
- Outstanding achievement with enough evidence in all SBOs : Pass (A+)
- Good achieved in the SBOs 1 and 2: Pass (C).
- Good achieved in the SBOs 1 - 2, and actively conducted SBO 3: Pass (B).
Based on written summary of papers (A4 1 page, twice a month). good achievement including SBO 4 is confirmed,: Pass (A).
- Outstanding achievement with enough evidence in all SBOs : Pass (A+)
Understanding of results, and ability to design next experiments will be evaluated by experimental notebook and discussion （50%）
A+: Superior (more than 90: top 10%)
A: Excellent (80-89: upper 20%)
B: Good (70-79)
C: Average (60-69)
D: Failure (less than 60)
Learning method
Out-of-class study: Read textbooks. Discuss with responsible faculty members and students, and improve own ability for creativity and a sense of independence.
Out-of-class study: Write summary on papers (2 per month) together with own opinion.
Out-of-class study: Learn and acquire stable and reliable experimental techniques.
Textbook
Requirement to earn credit
SOB.
Notes
Related Subjects
Practice in Internal Medicice I, II
Practice in Internal Medicice I, II
Seminar in Internal Medicice I, II