Subjects・Course Number
Laboratories
Language used （Japanese, English, Bilingual）
Availability for Students from Other Lab.
Contact Information for Students from Other Lab.
Course Type
Year
Semester,Day and Period
Room Number
Credit
mvb.biglobe.ne.jpmvb.biglobe.ne.jpmvb.biglobe.ne.jpCourse Overview
The instructor will give a lecture on general knowledge related to the presentation and the discussion.
Course Objectives (Learning Outcomes)
←SBO(Specific Behavior Objectives
GIO is for the student to develop abilities of independently planning and conducting research on hematology, and of evaluating the results. To accomplish these aims, the students learn techniques on molecular biology, cell biology, animal experiments, histopathology, genetic analysis, and clinical study. The research results obtained and presented by students shall be used for discussion on the pathogenesis of blood diseases and the development of new therapeutics.
Specific Behavior Objectives (SBO)
1. To be able to present the purpose, methods, results and significance of the students' own research, and to plan future research.
2. To be able to understand the questions and comments on the students' own presentation, to properly answer to them and make a discussion, and to reflect the content of discussions on improving the quality of research.
3. To be able to understand the content of other students' presentations and further their significance and shortcomings, and to ask questions and debates to help improve them.
4. To be able to understand the regulations and research methods related to recombinant DNA experiments, and to plan, complete a document on, and implement recombinant DNA experiments appropriately.
5. To be able to understand the regulations on animal experiments, and to plan, complete a document on, and implement animal experiments appropriately.
6. To be able to understand the regulations and bioethical issues on human genome research, and to plan, complete a document on, and implement human genome research.
7. To be able to understand pathogenesis of hematologic diseases at the cellular levels, to explain the remaining problems and experimental approaches to resolve them, and to describe future visions in the field.
GIO is for the students to understand the content of the original English papers. Thgough reading those, the students will understand standards of leading research on blood disorders, grasp the research trends in the world, and plan their own unique and valuable research projects .
Specific Behavior Objectives (SBO)
１. To be able to select one or a few to read from the latest original papers using the on-line search system.
２. To be able to read and understand the selected papers, explain the outline to other students within a specified time, and answer questions from other students.
３. To be able to read the paper(s) selected by other students in advance, understand the content, ask questions, and discuss the significance of the study after listening to the explanation by the presenter.
４. To be able to explain the historical significance of each original article.
GIO is for the students to lay the foundation to become those who intend to develop and improve medical research. To achieve this, the students need to actively plan and conduct research on their own, after learning methods on molecular and cell biological experiments, animal experiments, histopathological analysis, and clinical study that underly hematology research.
Specific Behavior Objectives (SBO)
１．To be able to learn the basics of research techniques such as molecular and cell biological experiments, animal experiments, histopathological analysis, and clinical research. Specific techniques include, cell culture, PCR, DNA sequencing (including high-speed sequencing) and analysis, Western blotting, ELISA, flow cytometry, immunohistological staining, disease model mouse analysis, statistical analysis, etc.
２．To be able to make a research plan for each theme and execute it.
３．To beable to assess the creativity and significance of your research plan and results in the relevant field, and reflect it in your next plan.
４．To be able to report the progresses on the findings and the significance within the study group once a week, and to make a debate on other students' reports.
５．To beb able to make presentations at academic societies in the field.
Keyword
Course Schedule
第1回（月日、時限）担当教員名 講義内容など
Students will present their research objectives, methods, results and their significance, and future research to be conducted, take questions and comments, and respond to them in the assigned class. Other students understand the content of the presentation, including its significance and shortcomings, and ask questions and debates to improve it.
Assign students in order for the selection of an original paper and the explanation of its content. The assigned students should report in advance the selected paper and read and understood before the class. In class, the outline will be explained to the instructor and other students within the specified time, and questions will be answered. Students who are not assigned will read the paper in advance and discuss any questions and the significance of the study. The debate includes the historical significance of the original article.
After setting the research theme, students will learn the basics of the research method, focusing on those related to their own research theme. Students will perform experiments based on their own experimental plans, and present and discuss the results. Based on these results and discussions, a subsequent experiment plan is drawn up, and the cycle of performing experiments, presenting the results, and making discussions is repeated.
Course prerequisite
Grading Criteria
Judgment criteria of B or higher: Judged as C or higher, and SBO 3 is actively performed.
Judgment criteria of A or higher: Judged as B or higher, and it is judged that SBO 4 to 7 can be roughly performed according to the guidance.
Judgment criteria of A+: Judged as A or higher, and SBO 1 to 7 are judged to be particularly excellent.
Judgment criteria of B or higher: Judged as C or higher, and SBO 3 is actively performed.
Judgment criteria of A or higher: Judged as B or higher, and it is judged that SBO 4 is achieved.
Judgment criteria of A+: Judged as A or higher, and .it is judged that he student is particularly excellent.
Judgment criteria of B or higher: Judged as C or higher, and
it is judged that the student is actively drafting and executing experiments on research themes.
Judgment criteria of A or higher: Judged as B or higher, and
the student is able to properly explain and discuss the significance of research theme.
Judgment criteria of A+: Judged as A or higher, and the student is evaluated as reachingi a sufficient level for writing a dissertation.
Learning method
Out-of-class learning: Conduct their own research based on the knowledge and skills obtained in this course. Also see separate sheets.
Out-of-class learning: Conduct their own research based on the knowledge and skills obtained in this course. Also see separate sheets..
Out-of-class learning: see separate sheets.
Textbook
Edited by Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J. International Agency for Research on Cancer (IARC), 2017
Edited by Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J. International Agency for Research on Cancer (IARC), 2017
Edited by Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J. International Agency for Research on Cancer (IARC), 2017
Requirement to earn credit
Attendance of 5 hours or more to other lab's classes.
Attendance of 5 hours or more to other lab's classes.
Notes
Presentations should be made using PowerPoint, etc.
What the students do not understand should be asked and resolved at the class..
Conduct scientific, logical, and rigorous discussions.
What the students do not understand should be asked and resolved at the class..
Conduct scientific, logical, and rigorous discussions.
What the students do not understand should be asked and resolved at the class..
Conduct scientific, logical, and rigorous discussions.
Relation to Other Courses
Practice in Internal Medicin I, II
Practice in Internal Medicin I, II
Seminar in Internal Medicin I, II