シラバス Syllabus | Doctoral Program in Medical Sciences | ||
---|---|---|---|
科目番号 Course Number |
0BTNE41 / 0BTNE43 | 0BTNE45 / 0BTNE47 | 0BTNE49 / 0BTNE4B |
科目名 Subjects |
Lecture and Discussion in Medical Science of Sleep I Lecture and Discussion in Medical Science of Sleep II |
Seminar in Medical Science of Sleep I Seminar in Medical Science of Sleep II |
Practice in Medical Science of Sleep I Practice in Medical Science of Sleep Ⅱ |
研究分野 Laboratories |
Electrophysiology and molecular biology of sleep | Electrophysiology and molecular biology of sleep | Electrophysiology and molecular biology of sleep |
使用言語 Language used (Japanese, English, Bilingual) |
Japanese or English | Japanese or English | Japanese or English |
他研究室学生の受け入れの可否(〇×) Availability for students from other lab. |
○ possible | ○ possible | TBD upon request. |
他研究室学生の問い合わせ先 Contact Information for Students from Other Lab. |
honjoh.sakiko.gf | honjoh.sakiko.gf | honjoh.sakiko.gf |
授業形態 Course Type |
Lecture, presentation and discussion | Seminar | Practice |
標準履修年次 Year |
1 or 2 | 1 or 2 | 1 or 2 |
実施学期・曜時限等 Semester,Day and Period |
ⅠSpring semester / ⅡAutumn semester | ⅠSpring semester / ⅡAutumn semester | ⅠSpring semester / ⅡAutumn semester |
開講場所 Room Number |
IIIS building conference room, other | IIIS building conference room, other | IIIS building conference room, other |
単位数 Credit |
Spring and Autumn semester, 2 x 2 credits | Spring and Autumn semester, 2 x 2 credits | Spring and Autumn semester, 2 x 2 credits |
担当教員名・オフィスアワー等 | (make an appointment by E-mail) | (make an appointment by E-mail) | (make an appointment by E-mail) |
Faculty Members and E-mail | HONJOH Sakiko: honjoh.sakiko.gf | HONJOH Sakiko: honjoh.sakiko.gf | HONJOH Sakiko: honjoh.sakiko.gf |
授業概要 Course overview |
Students learn skills to design and perform experiments, and evaluate the experimental resultsthrough discussingyour own results concerning the molecular and neural mechanisms of sleep. | This is a literature-based, seminar-type course. Students will acquire skills to understand the purpose, methods, and results of latest articles related to Infection Biology and discuss the significances, problems, and future directions of the study. | In this course, students will practically learn methods, experimental principles, and safe handling techniques required for the research in Infection Biology. |
学位プログラム・コンピテンスとの関係Competence |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
授業の到達目標(学修成果) Course Objectives (Learning Outcomes) ←SBO(Specific Behavior Objectives |
1. To be able to give a presentation about your own research objectives, methods, results, and future directions. 2. To be able to explain originality and creativity of your own research project. 3. To be able to accept criticisms from other participants to improve your own research project. 4. To be able to understand the presentations ofother speakers, and provideconstructive criticism. 5. To be able to design and perform experiments of recombinant DNA according to the Act concerning recombinant DNA experiment. 6. To be able to design and perform the animal experiments according to the bioethical rule. 7. To build abilities to presentand publish your own experimental results. |
1. To develop an ability to select important articles from latest ones by using online search service. 2. To develop an ability to introduce research topics to a general audience in time given. 3. To be able to discuss the unclear points and significances of the articles which are explained by other paticipants. 4. To develop an ability to evaluatethe significance of the selected articles in the related field of research. |
1. To be able to perform basic mouse handling. 2. To be able to understand basis of EEG/EMG recording and prepare electrodes for it. 3. To be able to perform streotaxic EEG/EMG electrode implantation surgery. 4. To be able to perform chronic recording of EEG and EMG in free-behaving mice. 5. To be able to analyze data and perform sleep/wake scoring. 6. To be able to prepare mouse brain slices and detect genes of interest by immunohistochemistry etc. |
キーワード Keyword |
Sleep, brain wave, gene expression | Sleep, brain wave, gene expression | Sleep, brain wave, gene expression |
授業計画 Course Schedule 第1回(月日、時限)担当教員名 講義内容など |
Weekly, Tuesday 18:00- Through lecture and discussion series, students acquire knowledge and creativity to set proper research objective, select appropriate methodology, understand the significance of results, and to further design following experiments independently, concerning 1) The dynamics of thalamocortical system across sleep/wake cycles2) Neural circuits underlying NREM sleep specific EEG patterns3) Vigilance state-depedent transcriptional changes4) Functions of vigilance-state dependent gene expression in neural activity. In additions, students also learn and confirm general knowledge underlying each specific subjects. |
Weekly, Tuesday 19:30- Class meets every week. Topics to be discussed will be selected by students. Points to be learned include: How to select papers. Histrical background and creativity of good scientific papers. Structure of scientific papers. How to interpretate the results. Logical flow in scientific papers. |
Class meets every week. 1. Basic mouse handling 2. Preparation of electrodes for EEG/EMG recording. 3. Stereotaxic electrode implantation surgery 4. Chronic recodring of EEG and EMG in free-behaving mice. 5. Data analysis and sleep/wake scoring. 6. Preparation of mouse brain slices and immunohitochemistry |
履修条件 Course prerequisite |
None | None | None |
成績評価方法 Grading Criteria |
Students are evaluated by the achievement of the objectives listed in the SBO. - Good achieved under supervision in the SBOs 1 and 2: Pass (C). - Good achieved under supervision in the SBOs 1 - 3, and actively conducted SBO 4: Pass (B). SBOs 1 - 3 will be evaluated based on a brief report in terms of presentation and dicsussion. - Excellent achievement in SBOs 1-4, and good achievement in SBOs 5-7: (A) - Outstanding achievement with enough evidence in all SBOs : Pass (A+) |
Students are evaluated by the achievement of the objectives listed in the SBO. - Good achieved in the SBOs 1 and 2: Pass (C). - Good achieved in the SBOs 1 - 2, and actively conducted SBO 3: Pass (B). Based on written summary of papers (A4 1 page). good achievement including SBO 4 is confirmed,: Pass (A). - Outstanding achievement with enough evidence in all SBOs : Pass (A+) |
Skills to obtain reliable experimental results (50%) Understanding of results, and ability to design next experiments will be evaluated by experimental notebook and discussion (50%) A+: Superior (more than 90: top 10%) A: Excellent (80-89: upper 20%) B: Good (70-79) C: Average (60-69) D: Failure (less than 60) |
学修時間の割り当て及び授業外における学修方法 Learning method |
Lecture 100% Out-of-class study: Read textbooks. Discuss with responsible faculty members and students, and improve own ability for creativity and a sense of independence. |
Training (Seminar) 100% Out-of-class study: Write summary on papers (2 per month) together with own opinion. |
Experiment, Practice 100% |
教材・参考文献 Textbook |
To be announced, if any. | Research articles to be discussed for each class will be provided as PDF files. | Basic protocols for experiments will be provided. |
単位取得要件 Requirement to earn credit |
Requirement to earn credit: Attendance 80% or more. Attendance of 5 hours or more to other lab's classes. |
Requirement to earn credit: Attendance 80% or more. Attendance of 5 hours or more to other lab's classes. |
Requirement to earn credit: Attendance 80% or more. |
その他(受講上の注意点等) Notes |
Students have to attend the course of Practice in Medical Science of Sleep too. Students should resolve the questions immediately. Students should thoroughly discuss scientifically, logically, and properly. |
Students should resolve the questions immediately. Students should thoroughly discuss scientifically, logically, and properly. |
Students should contact a responsible faculty member, and get permission beforehand. Students should resolve the questions immediately. |
他の授業科目との関連 Relation to Other Courses |
Seminar in Medical Science of Sleep I, II Practice in Medical Science of Sleep I, II |
Lecture and Discussion in Medical Science of Sleep I, II Practice in Medical Science of Sleep I, II |
Lecture and Discussion in Medical Science of Sleep I, II Seminar in Medical Science of Sleep I, II |
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