シラバス Syllabus | Doctoral Program in Medical Sciences | ||
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科目名・科目番号 Subjects・Course Number |
Lecture and Discussion in Clinical Pathophysiology Ⅰ/ 0BTNE51 | Seminar in Clinical Pathophysiology I/ 0BTNE55 | Practice in Clinical Pathophysiology I/ 0BTNE59 |
Lecture and Discussion in Clinical Pathophysiology Ⅱ / 0BTNE53 | Seminar in Clinical Pathophysiology II/ 0BTNE57 |
Practice in Clinical PathophysiologyⅡ/ 0BTNE5B |
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研究分野 Laboratories |
Biostatistics | Biostatistics | Biostatistics |
使用言語 Language used (Japanese, English, Bilingual) |
Bilingual | Bilingual | Bilingual |
他研究室学生の受け入れの可否(〇×) Availability for students from other lab. |
× | × | × |
他研究室学生の問い合わせ先 Contact Information for Students from Other Lab. |
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授業形態 Course Type |
Lecture, presentation and discussion | Seminar | Practice |
標準履修年次 Year |
1 or 2 | 1 or 2 | 1 or 2 |
実施学期・曜時限等 Semester,Day and Period |
ⅠSpring semester / ⅡAutumn semester | ⅠSpring semester / ⅡAutumn semester | ⅠSpring semester / ⅡAutumn semester |
開講場所 Room Number |
Conference room, other | Conference room, other | Conference room, other |
単位数 Credit |
Spring and Autumn semester, 2 x 2 credits | Spring and Autumn semester, 2 x 2 credits | Spring and Autumn semester, 2 x 2 credits |
担当教員名・オフィスアワー等 | (make an appointment by E-mail) | (make an appointment by E-mail) | (make an appointment by E-mail) |
Faculty Members and E-mail | GOSHO Masahiko, mgosho | GOSHO Masahiko, mgosho | GOSHO Masahiko, mgosho |
MARUO Kazushi, maruo | MARUO Kazushi, maruo | MARUO Kazushi, maruo | |
授業概要 Course overview |
The course overviews classical and modern methods on biostatistics. Lectures cover current statistical methodologies and their performance. | The course overviews on classical and modern methods on biostatistics. Lectures cover the principle and properties of statistical methodologies. Students also discuss the significances and issues of the methods. | The course overviews Monte Carlo simulation studies in clinical trials. Lectures cover the simulation methods and showing the simulation results. |
学位プログラム・コンピテンスとの関係Competence (学位P共通) |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
授業の到達目標(学修成果) Course Objectives (Learning Outcomes) ←SBO(Specific Behavior Objectives |
1. To be able to preset the statistical methods for planning of medical researches. 2. To be able to preset the statistical methods for data analyses. 3. To be able to explain the indexes and criteria for evaluating the performance of the statistical methods. |
1. To be able to select appropriate articles. 2. To be able to understand the articles and explain the outline of the articles. 3. To be able to discuss the significances and issues of the articles. |
1. To be able to design simulation studies for evaluating the performance of statistical methods. 2. To be able to general the random numbers based on actual clinical trials. 3. To be able to provide efficient program codes. 4. To be able to explain and summarize simulation results. |
キーワード Keyword |
Unbiasedness, consistency, asymptotic normality, asymptotic efficiency of estimates, test size, power | Unbiasedness, consistency, asymptotic normality, asymptotic efficiency of estimates, test size, power | Test size, power, bias, coverage probability, standard error, empirical standard deviation, mean squared error |
授業計画 Course Schedule 第1回(月日、時限)担当教員名 講義内容など |
Statistical method for designing the intervention and observational studies Statistical method for data analysis |
Selection of articles Structure of the articles for biostatistics Principle and property of statistical methods Simulation studies for evaluating the performance of statistical methods Application and data analysis |
Designing simulation studies Investigating examples and simulation scenarios Random numbers and probability distributions Mean and error models |
履修条件 Course prerequisite |
If students want to attend the course, you should be contact the responsible teacher. | If students want to attend the course, you should be contact the responsible teacher. | If students want to attend the course, you should be contact the responsible teacher. |
成績評価方法 Grading Criteria |
Grading will be based on the levels of achievements of SBO evaluated by presentations and discussions in the class. General achievements in SBO 1-2 with supervisors' instructions will be evaluated to pass (C or upper). General achievements in SBO 1-3 with supervisors' instructions will be evaluated as B or upper. In addition to the above, active participation and sufficient understanding will be evaluated as A. |
Grading will be based on the levels of achievements of SBO evaluated by presentations and discussions in the class. General achievements in SBO 1-2 with supervisors' instructions will be evaluated to pass (C or upper). General achievements in SBO 1-3 with supervisors' instructions will be evaluated as B or upper. In addition to the above, active participation and sufficient understanding will be evaluated as A. |
Grading will be based on the levels of achievements of SBO evaluated by presentations and discussions in the class. General achievements in SBO 1-2 with supervisors' instructions will be evaluated to pass (C or upper). General achievements in SBO 1-3 with supervisors' instructions will be evaluated as B or upper. In addition to the above, active participation and sufficient understanding will be evaluated as A. |
学修時間の割り当て及び授業外における学修方法 Learning method |
Lecture, Discussion 100% Out-of-class study: None |
Training (Seminar) 100% Out-of-class study: None |
Experiment, Practice 100% Out-of-class study: None |
教材・参考文献 Textbook |
Text books will be specified every class. | Original articles of Biometrics,Statistics in Medicine,Biometrika,Statistics Methods in Medical Research, etc. | Rubinstein, R. Y. and Kroese, D. P. (2016). Simulation and the Monte Carlo method, 3rd edition. John Wiley & Sons. Chang, M. (2010). Monte Carlo simulation for the pharmaceutical industry: concepts, algorithms, and case studies. CRC Press. |
単位取得要件 Requirement to earn credit |
Requirement to earn credit: Attendance 80% or more and presentation. | Requirement to earn credit: Attendance 80% or more and presentation. | Requirement to earn credit: Attendance 80% or more and presentation. |
その他(受講上の注意点等) Notes |
Students majoring in biostatistics are eligible. | Students majoring in biostatistics are eligible. | Students majoring in biostatistics are eligible. |
他の授業科目との関連 | Seminar in Clinical Pathophysiology I, II Practice in Clinical Pathophysiology I, II |
Lecture and Discussion in Clinical Pathophysiology I, II Practice in Clinical Pathophysiology I, II |
Lecture and Discussion in Clinical Pathophysiology I, II Seminar in Clinical Pathophysiology I, II |
ティーチングフェロー(TF)・ティーチングアシスタント(TA) | To be announced, if any. | To be announced, if any. | To be announced, if any. |
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