シラバス Syllabus | Doctoral Program in Medical Sciences | ||
---|---|---|---|
科目名・科目番号 Subjects・Course Number |
Lecture and Discussion in Internal Medicine I / 0BTNE71 | Seminar in Internal Medicine I / 0BTNE75 | Practice in Internal Medicine I /0BTNE79 |
Lecture and Discussion in Internal Medicine II/ 0BTNE73 | Seminar in Internal Medicine II/ 0BTNE77 | Practice in Internal Medicine II/ 0BTNE7B | |
研究分野 Laboratories |
Pediatrics and Child Health | Pediatrics and Child Health | Pediatrics and Child Health |
使用言語 Language used (Japanese, English, Bilingual) |
Bilingual | Bilingual | Bilingual |
他研究室学生の受け入れの可否(〇×) Availability for students from other lab. |
〇 | 〇 | 〇 |
他研究室学生の問い合わせ先 Contact Information for Students from Other Lab. |
Tel (5635) or e-mail to teachers | Tel (5635) or e-mail to teachers | Tel (5635) or e-mail to teachers |
授業形態 Course Type |
Lecture, presentation and discussion | Seminar | Practice |
標準履修年次 Year |
1 or 2 | 1 or 2 | 1 or 2 |
実施学期・曜時限等 Semester,Day and Period |
ⅠSpring semester / ⅡAutumn semester | ⅠSpring semester / ⅡAutumn semester | ⅠSpring semester / ⅡAutumn semester |
開講場所 Room Number |
Conference room, other | Conference room, other | Conference room, other |
単位数 Credit |
Spring and Autumn semester, 2 x 2 credits | Spring and Autumn semester, 2 x 2 credits | Spring and Autumn semester, 2 x 2 credits |
担当教員名・オフィスアワー等 | (Make an appointment by E-mail) | (Make an appointment by E-mail) | (Make an appointment by E-mail) |
Faculty Members and E-mail | TAKADA Hidetoshi, TakadaH | TAKADA Hidetoshi, TakadaH | TAKADA Hidetoshi, TakadaH |
KOBAYASHI Chie, ckobayashi | KOBAYASHI Chie, ckobayashi | KOBAYASHI Chie, ckobayashi | |
SAITO Makoto, msaito tokai.or.jp | SAITO Makoto, msaito tokai.or.jp | SAITO Makoto, msaito tokai.or.jp | |
MIYAZONO Yayoi, y-myz | MIYAZONO Yayoi, y-myz | MIYAZONO Yayoi, y-myz | |
OHTO Tatsuyuki, tohto | OHTO Tatsuyuki, tohto | OHTO Tatsuyuki, tohto | |
FUKUSHIMA Hiroko, fkhiroko | FUKUSHIMA Hiroko, fkhiroko | FUKUSHIMA Hiroko, fkhiroko | |
授業概要 Course overview |
The purpose of our research is to 1. Investigate the physiologic and pathologic processes of growth and development in terms of molecular mechanism in embryogenesis, differentiation, apoptosis and regeneration. 2. Create methods on the basis of the above results to improve human health and control diseases. 3. Cultivate researchers who can apply ideas of bioethics to improve quality of lives of infants and children. |
To be able to understand the most recent world’s leading research data regarding mechanism of normal development of humans, the pathophysiology of pediatric disorders including abnormal development, and to plan original and valuable project based on the study trend in the world as a researcher in this field. | To be able to explain the reliability of the experimental data by learning principle and methods in pediatric research on disorders of fetuses and children. To be able to do theoretical clinical approach in pediatric medicine. To be able to contribute to the development of new diagnostic or therapeutic methods for disorders of childhood. |
学位プログラム・コンピテンスとの関係Competence |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
【Generic Competence】Intellectual creativity, Communication skills 【Specific Competence】Research planning skills, Cutting-edge research execution skills, Working knowledge in the specialized field, Information and communication technology skills |
【Generic Competence】Intellectual creativity, 【Specific Competence】 Cutting-edge research execution skills, Working knowledge in the specialized field |
授業の到達目標(学修成果) Course Objectives (Learning Outcomes) ←SBO(Specific Behavior Objectives |
1. To be able to explain the notion of pediatric disorders. 2. To be able to explain the pathogenic mechanism of pediatric disorders. 3. To understand and to be able to explain the principle of laboratory examinations used in the field of pediatric medicine. 4. To understand and to be able to explain the principle of laboratory examinations used for the diagnosis of pediatric disorders. 5. To understand and to be able to explain the principle of methods to treat pediatric disorders. 6. To understand and to be able to explain the general condition of children and the relationships between the circumstances. 7. To be able to explain the reason of excellence, significance and originality of their study in the world. 8. To be able to apply the results of the discussion in their own study with correct understanding of its contents. 9. To be able to provide constructive opinion and promote discussion regarding the study results of other students based on the understanding of their meaning and problems. 10. To be able to plan and perform experiments appropriately with the knowledge of rules and ethical problems in the field of life science. |
1. To be able to select valuable publications among a lot of original articles in various journals and on line search system. 2. To be able to evaluate the significance of the selected original articles and to explain their essence to others during the allotted time period. 3. To be able to discuss the significance and questionable points in the publications. 4. To be able to explain the original articles in the view of the historical significance and current situation in the whole picture of the life sciences. |
1. To understand the methods to identify and validate novel genetic causes of pediatric disorders. 2. To understand and acquire the principle and techniques for the analysis of gene function through cell culture and by making genetically engineered mice. 3. To be able to make disease-specific iPS cells, and to understand the usefulness of iPS cells for the analysis of pathophysiology and for the establishment of new therapy. 4. To be able to analyze the pathophysiology of arrhythmia of fetuses and children by using magnetocardiography. |
キーワード Keyword |
Fetal development,, Development of children, Growth of children, Genetic diseases, Chromosomal diseases, Environment and genes | Pathophysiology of pediatric diseases, genetic tests, immunological analysis, in silico analysis, functional analysis, statistical analysis | Next generation sequencer, genetically engineered mice, iPS cells, magnetocardiogram |
授業計画 Course Schedule 第1回(月日、時限)担当教員名 講義内容など |
Students are also encouraged to attend the meeting held from 11:00 on Wednesday, from 13:00 on Thursday, and from 8:00 on Friday. Contents: Pathophysiology of pediatric diseases, genetic analysis, cause and pathophysiology of immunodeficiency, and gene therapy etc. |
Students will learn the followings. To select valuable original articles, and to be able to find historical significance and originality in them. To grasp the composition of the original articles. To gain proficiency in reading the original articles. To interpret the theoretical development and cohesiveness of the original articles. Self Study Students are recommended to read specified original articles beforehand, and to prepare to point out questions to solve in the discussion with tutors regarding them. Students are also encouraged to attend the meeting held from 11:00 on Wednesday, from 13:00 on Thursday, and from 8:00 on Friday. Contents: Pathophysiology of pediatric diseases, genetic analysis, cause and pathophysiology of immunodeficiency, and gene therapy etc. |
Students will learn the followings. 1. Learn the methods of Bioinformatics applying next-generation-sequencer and genome-wide association study. 2. Make gene-engineered mice. 3. Make iPS cells and to induce them to differentiated cells of aim based on the knowledge of the methods to recapitulate the disorders and of the methods to search new drugs by drug screening using iPS cells. 4. Be able to perform magnetocardiographic analaysis. 5. Learn how to plan studies of pediatric medicine, important points in the ethical review application and methods of statistical analysis. Self Study Students can repeat the technical procedures of experiments to obtain stable and reliable results. Students are also encouraged to attend the meeting held from 11:00 on Wednesday, from 13:00 on Thursday, and from 8:00 on Friday. Contents: Pathophysiology of pediatric diseases, genetic analysis, cause and pathophysiology of immunodeficiency, and gene therapy etc. |
履修条件 Course prerequisite |
Students are required to solve the preblems and points of uncertainty by asking teachers about them or by scientific discussion. | Students are required to solve the preblems and points of uncertainty by asking teachers about them or by scientific discussion. | Students are required to solve the preblems and points of uncertainty by asking teachers about them or by scientific discussion. |
成績評価方法 Grading Criteria |
Students are evaluated by the achievement of the objectives listed in the SBO. - Good achieved under supervision in the SBOs 1 and 2: Pass (C). - Good achieved under supervision in the SBOs 1 - 3, and actively conducted SBO 4: Pass (B). SBOs 1 - 3 will be evaluated based on a brief report in terms of presentation and dicsussion. - Excellent achievement in SBOs 1-4, and good achievement in SBOs 5-7: (A) - Outstanding achievement with enough evidence in all SBOs : Pass (A+) |
Students are evaluated by the achievement of the objectives listed in the SBO. - Good achieved in the SBOs 1 and 2: Pass (C). - Good achieved in the SBOs 1 - 2, and actively conducted SBO 3: Pass (B). Based on written summary of papers (A4 1 page, twice a month). good achievement including SBO 4 is confirmed,: Pass (A). - Outstanding achievement with enough evidence in all SBOs : Pass (A+) |
Skills to obtain reliable experimental results (50%) Understanding of results, and ability to design next experiments will be evaluated by experimental notebook and discussion (50%) A+: Superior (more than 90: top 10%) A: Excellent (80-89: upper 20%) B: Good (70-79) C: Average (60-69) D: Failure (less than 60) |
学修時間の割り当て及び授業外における学修方法 Learning method |
Lecture 100% Out-of-class study: Read textbooks. Discuss with responsible faculty members and students, and improve own ability for creativity and a sense of independence. |
Training (Seminar) 100% Out-of-class study: Write summary on papers (2 per month) together with own opinion. |
Experiment, Practice 100% Out-of-class study: Learn and acquire stable and reliable experimental techniques. |
教材・参考文献 Textbook |
『Nelson Textbook of Pediatrics』 Saunders, 2016 | 『Nelson Textbook of Pediatrics』 Saunders, 2016 | 『Nelson Textbook of Pediatrics』 Saunders, 2016 |
単位取得要件 Requirement to earn credit |
Requirement to earn credit: Attendance 80% or more. Attendance to othe lab is recommended. |
Requirement to earn credit: Attendance 80% or more. Attendance of 5 hours or more to other lab's classes. |
Requirement to earn credit: Attendance 80% or more. SOB. |
その他(受講上の注意点等) Notes |
None | None | None |
他の授業科目との関連 Related Subjects |
Seminar in Internal Medicice I, II Practice in Internal Medicice I, II |
Lecture and Discussion in Internal Medicice I, II Practice in Internal Medicice I, II |
Lecture and Discussion inInternal Medicice I, II Seminar in Internal Medicice I, II |
ティーチングフェロー(TF)・ティーチングアシスタント(TA) | To be announced, if any. | To be announced, if any. | To be announced, if any. |
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