1.Doishita S, Inokuma S, Asashima H, Nakachi S, Matsuo Y, Rokutanda R, Kobayashi S, Hagiwara K, Satoh T, Akiyama O.:
Serum KL-6 level as an indicator of active or inactive interstitial pneumonitis associated with connective tissue diseases.
Intern Med. 50: 2889-92, 2011.

2.Sumida T, Iizuka M, Asashima H, Tsuboi H, Matsumoto I.：
Pathogenic role of anti-M3muscarinic acetylcholine receptor immune response in Sjogren's syndrome.
Presse Med.41(9 Pt 2):e461-6,2012

3.Asashima H, Inokuma S, Nakachi S, Matsuo Y, Rokutanda R, Hagiwara K, Kobayashi S.:
Extremely high salivary b2-microglobulin and Na+ levels in a Sjoren syndrome patient.
Int J Rheum Dis. 15: e31-3, 2012.

4.Asashima H, Inokuma S, Yamada H.:
Step by step improvement of peripheral polyneuropathy associated with Churg-Strauss syndrome by six courses of high-dose intravenous immunoglobulin therapy.
Allergol Int. 61: 503-5, 2012.

5.Iizuka M, Tsuboi H, Matsuo N, Kondo Y, Asashima H, Matsui M, Matsumoto I, Sumida T.:
The crucial roles of IFN-g in the development of M3 muscarinic acetylcholine receptor induced Sjogren's syndrome-like sialadenitis.
Mod. Rheumatol 23(3):614-6, 2013

6.Sumida T, Tsuboi H, Iizuka M, Asashima H, Matsumoto I.:
Anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjogren's syndrome.
Mod. Rheumatol 23(5): 841-5, 2013

7.Tsuboi H, Hagiwara S, Asashima H, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Matsumoto I, Sumida T.:
Validation of different sets of criteria for the diagnosis of Sjogren's syndrome in Japanese patients.
Mod. Rheumatol 23(2):219-25, 2013

8.Wakabayashi K, Inokuma S, Matsubara E, Onishi K, Asashima H, Nakachi S, Hagiwara K.:
Serum b2-microglobulin level is a useful indicator of disease activity and hemophagocytic syndrome complication in systemic lupus erythematosus and adult-onset Still?fs disease.
Clin Rheumatol. 32(7): 999-1005, 2013.

9.Asashima H, Inokuma S, Onoda M, Oritsu M.:
Cutoff levels of salivary b2-microglobulin and Na+ differentiating patients with Sjogren syndrome from those without it and healthy controls.
Clin Exp Rheumatol. 31(5): 699-703, 2013.

10.Hagiya C, Tsuboi H, Yokosawa M, Hagiwara S, Takai C, Hirota T, Asashima H, Miki H, Umeda N, Horikoshi M, Kondo Y, Sugihara M, Ogishima H, Suzuki T, Hiraoka T, Kaji Y, Matsumoto I, Ohshika T, Sumida T.:
Clinicopathological features of IgG4-related disease complicated with orbital involvement.
Mod Rheumatol 24(3):471-6,2014

11.Tsuboi H, Asashima H, Takai C, Hagiwara S, Hagiya C, Yokosawa M, Hirota T, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Yoshifuji H, Ohta A, Matsumoto I, Sumida T.:
Primary and secondary surveys on epidemiology of Sjogren's syndrome in Japan.
Mod Rheumatol 24(3):464-70,2014

12.Sumida T, Tsuboi H, Iizuka M, Hirota T, Asashima H, Matsumoto I. :
The role of M3 muscarinic acetylcholine receptor reactive T cells in Sjogren's syndrome: A Critical Review
J. Autoimmunity 51:44-50,2014

13.Iizuka M, Tsuboi H, Asashima H, Hirota T, Kondo Y, Matsui M, Matsumoto I, Sumida T.:
M3 muscarinic acetylcholine receptor reactive IL-17- producing T cells promotes development of Sjogren's syndrome like sialadenitis.
Mod Rheumatol 25(1):158-60, 2015

14.Sumida T, Tsuboi H, Asashima H, Iizuka M, Matsumoto I.:
Highlights from the 12th International Symposium on Sjogren's Syndrome in Kyoto, Japan.
Sjogren's Quarterly 9(1):8-14,2014

15.Hagiwara S, Tsuboi H, Hagiya C, Yokosawa M, Hirota T, Ebe H, Takahashi H, Ogishima H, Asashima H, Kondo Y, Umeda N, Suzuki T, Hitomi S, Matsumoto I, Sumida T.:
Pulmonary nocardiosis in patients with connective tissue disease: A report of two cases.
Intractable Rare Dis Res 3(1):25-28,2014

16.Ebe H, Tsuboi H, Hagiya C, Takahashi H, Yokosawa M, Hagiwara S, Hirota T, Kurashima Y, Takai C, Miki H, Asashima H, Umeda N, Kondo Y, Ogishima H, Suzuki T, Chino Y, Matsumoto I, Sumida T.:
Clinical features of patients with IgG4-related disease complicated with perivascular lesions.
Mod Rheumatol 25(1):105-9,2015

17.Tsuboi H, Ohira H, Asashima H, Tsuzuki S, Iizuka M, Matsuo N, Kondo Y, Matsumoto I, Sumida T.:
Anti-M3 muscarinic acetylcholine receptor antibodies in patients with primary biliary cirrhosis.
Hepatol Res 44(14):E471-9,2014

18.Iizuka M, Wakasa Y, Tsuboi H, Asashima H, Hirota T, Kondo Y, Matsumoto I, Sumida T, Takaiwa F.:
Prophylactic effect of the oral administration of transgenic rice seeds containing altered peptide ligands of type II collagen on rheumatoid arthritis.
Biosci Biotech Bioch 78(10):1662-8,2014

19.Tsuboi H, Nakai Y, Iizuka M, Asashima H, Hagiya C, Tsuzuki S, Hirota T, Miki H, Hagiwara S, Kondo Y, Tanaka A, Moriyama M, Matsumoto I, Nakamura S, Yoshihara T, Abe K, Sumida T.:
DNA microarray analysis of labial salivary glands in IgG4-related disease. Comparison with Sjogren's syndrome.
Arthritis Rheum 66(10):2892-9,2014

20.Iizuka M, Wakasa Y, Tsuboi H, Asashima H, Hirota T, Kondo Y, Matsumoto I, Takaiwa F, Sumida T.:
Suppression of collagen-induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of type II collagen.
Plant Biotechnol J 12:(8):1143-53,2014

21.Tsuboi H, Matsumoto I, Hagiwara S, Hirota T, Takahashi H, Ebe H, Yokosawa M, Hagiya C, Asashima H, Takai C, Miki H, Umeda N, Kondo Y, Ogishima H, Suzuki T, Hirata S, Saito K, Tanaka Y, Horai Y, Nakamura H, Kawakami A, Sumida T.:
Efficacy and safety of abatacept for patients with Sjogren's syndrome associated with rheumatoid arthritis. ROSE (Rheumatoid Arthritis with Orencia Trial toward Sjogren's syndrome Endocrinopathy) trial. An open label, one-year, prospective study. Interim analysis of 32 patients for 24 weeks.
Mod Rheumatol 25(2):187-93,2015

22.Yokosawa M, Tsuboi H, Nasu K, Hagiya C, Hagiwara S, Hirota T, Ebe H, Takahashi H, Asashima H, Kondo Y, Ogishima H, Suzuki T, Minami M, Bukawa H, Matsumoto I, Sumida T.:
Usefulness of MR imaging of the parotid glands in patients with secondary Sjogren’s syndrome associated with rheumatoid arthritis.
Mod Rheumatol 25(3):415-20,2015

23.Takahashi H, Tsuboi H, Kurata I, Takahashi H, Inoue S, Ebe H, Yokosawa M, Hagiwara S, Hirota T, Asashima H, Kaneko S, Kawaguchi H, Kurashima Y, Miki H, Umeda N, Kondo Y, Ogishima H, Suzuki T, Matsumoto I, Sumida T.:
Predictors of the response to treatment in acute lupus 1 hemophagocytic syndrome.
Lupus 24(7):659-68,2015

24.Iizuka M, Tsuboi H, Matsuo N, Asashima H, Hirota T, Kondo Y, Iwakura Y, Takahashi S, Matsumoto I, Sumida T.:
A crucial role of RORgt in the development of spontaneous sialadenitis-like Sjogren's syndrome.
J Immunol 194(1):56-67,2015

25.Takahashi H, Tsuboi H, Ogishima H, Yokosawa M, Takahashi H, Yagishita M, Abe S, Hagiwara S, Asashima H, Umeda N, Kondo Y, Suzuki T, Matsumoto I, Sumida T.:
[18F]fluorodeoxyglucose positron emission tomography/computed tomography can reveal subclinical prostatitis in a patient with IgG4-related disease.
Rheumatology (Oxford) 54(6):1113,2015

26.Kurata I, Tsuboi H, Takahashi H, Yagishita M, Abe S, Ebe H, Takahashi H, Asashima H, Hirota T, Hagiwara S, Umeda N, Kondo Y, Ogishima H, Suzuki T, Matsumoto I, Sumida T.:
A case of relapsing neurosarcoidosis with brain nodules and hydrocephalus successfully treated by corticosteroid and methotrexate.
Rheumatology (Oxford) 54(7):1160,2015

27.Asashima H, Tsuboi H, Iizuka M, Hirota T, Kondo Y, Matsumoto I, Sumida T.:
The Anergy Induction of M3 Muscarinic Acetylcholine Receptor-Reactive CD4+ T Cells Suppresses Experimental Sialadenitis-like Sjogren's Syndrome.
Arthritis Rheum 67(8):2213-25,2015

28.Takahashi H, Tsuboi H, Abe S, Yokosawa M, Hagiwara S, Asashima H, Hirota T, Umeda N, Kondo Y, Matsumoto I, Sumida T.:
Magnetic resonance imaging can reveal fascial vasculitis in a patient with microscopic polyangiitis.
Scand J Rheumatol 44(6):511-3,2015

29.Miki H, Tsuboi H, Kaneko S, Takahashi H, Yokosawa M, Asashima H, Hirota T, Hagiwara S, Umeda N, Kondo Y, Nishimura B, Sugano M, Matsumoto I, Sumida T.:
A case of refractory Kimura disease with a buccal bulky mass successfully treated with
low-dose cyclosporine A: report and review of the literature.
Allergol Int 65(2):212-4,2016

30.Hagiwara S, Tsuboi H, Honda F, Takahashi H, Kurata I, Ohyama A, Yagishita M, Abe S, Kurashima Y, Kaneko S, Kawaguchi H, Takahashi H, Ebe H, Yokosawa M, Asashima H, Hirota T, Umeda N, Kondo Y, Matsumoto I, Sumida T.:
Association of anti-Ro/SSA antibody with response to biologics in patients with
rheumatoid arthritis.
Mod Rheumatol 26(6):857-862,2016

31.Tsuboi H, Matsumoto I, Hagiwara S, Hirota T, Takahashi H, Ebe H, Yokosawa M, Yagishita M, Takahashi H, Kurata I, Ohyama A, Honda F, Asashima H, Miki H, Umeda N, Kondo Y, Hirata S, Saito K, Tanaka Y, Horai Y, Nakamura H, Kawakami A, Sumida T.:
Effectiveness of abatacept for patients with Sjoren's syndrome associated with rheumatoid arthritis. An open label, multicenter, one-year, prospective study: ROSE (Rheumatoid Arthritis with Orencia Trial toward Sjoren's syndrome Endocrinopathy) trial.
Mod Rheumatol 26(6):891-899,2016

32.Hirota T, Tsuboi H, Iizuka-Koga M, Takahashi H, Asashima H, Yokosawa M, Kondo Y, Ohta M, Wakasa Y, Matsumoto I, Takaiwa F, Sumida T.:
Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of
glucose-6-phosphate-isomerase.
Mod Rheumatol 27(3):457-465,2017

33.Tahara M, Tsuboi H, Segawa S, Asashima H, Iizuka M, Hirota T, Takahashi H, Kondo Y, Matsui M, Matsumoto I, Sumida T.:
RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sjogren's syndrome-like sialadenitis.
Clin Exp Immunol 187(2):213-224,2017

34.Abe S, Tsuboi H, Toko H, Honda F, Ohyama A, Takahashi H, Yokosawa M, Asashima H, Hagiwara S, Hirota T, Kondo Y, Matsumoto I, Sakai S, Aonuma K, Sumida T.:
The effectiveness of upfront pulmonary vasodilators combination therapy in addition to corticosteroids for pulmonary arterial hypertension associated with systemic lupus erythematosus: two successful cases utilizing both corticosteroids and an upfront combination of vasodilators.
Modern Rheumatol Case Reports 1(2):73-78,2017

35.Tsuboi H, Hagiwara S, Asashima H, Takahashi H, Hirota T, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Matsumoto I, Sumida T.:
Comparison of the performance of new ACR-EULAR classification criteria for primary Sjogren's syndrome with former sets of criteria in Japanese patients.
Ann Rheum Dis 76(12):1980-1985,2017

36.Iizuka-Koga M, Asashima H, Ando M, Lai C-Y, Mochizuki S, Nakanishi M, Nishimura T, Tsuboi H, Hirota T, Takahashi H, Masumoto I, Otsu M, Sumida T.:
Functional analysis of dendritic cells generated from T-iPS cells from CD4+ T cell clones of Sjogren's syndrome.
Stem Cell Reports 8(5):1155-1163,2017

37.Honda F, Tsuboi H, Toko H, Ohyama A, Takahashi H, Abe S, Yokosawa M, Asashima H, Hagiwara S, Hirota T, Kondo Y, Matsumoto I, Sumida T.:
Recurrent Kikuchi-Fujimoto disease successfully treated by concomitant use of hydroxychloroquine and corticosteroid.
Intern Med 56(24):3373-3377,2017

38.Takahashi H, Tsuboi H, Asashima H, Hirota T, Kondo Y, Moriyama M, Matsumoto I, Nakamura S, Sumida T.:
cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjogren's syndrome.
Clin Exp Immunol 190(1):96-109,2017

39.Takahashi H, Tsuboi H, Yokosawa M, Asashima H, Hirota T, Kondo Y, Matsumoto I, Sumida T.:
Diffusion-weighted magnetic resonance imaging of parotid glands before and after abatacept therapy in patients with Sjogren's syndrome associated with rheumatoid arthritis: Utility to evaluate and predict response to treatment.
Mod Rheumatol 28(2):300-307,2018

40.Kawaguchi H, Tsuboi H, Yagishita M, Terasaki T, Terasaki M, Shimizu M, Honda F, Ohyama A, Takahashi H, Miki H, Yokosawa M, Asashima H, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
A case of severe adult-onset Still disease with constrictive pericarditis and pleuritis successfully treated with tocilizumab in addition to corticosteroid and cyclosporin A.
Intern Med 57(7):1033-1038,2018

41.Fujita-Tanaka H, Ogawa Y, Muro Y, Ogawa-Momohara M, Asashima H, Tsuboi H, Sumida T, Akiyama M.
Pansclerotic morphea associated with hypohidrosis and anti-M3 muscarinic acetylcholine receptor antibodies.
Br J Dermatol 178(3):e210-e211,2018

42.Yagishita M, Kondo Y, Terasaki T, Terasaki M, Shimizu M, Honda F, Oyama A, Takahashi H, Yokosawa M, Asashima H, Hagiwara S, Tsuboi H, Matsumoto I, Sumida T.
A case of clinically amyopathic dermatomyositis with interstitial pneumonia successfully treated with plasma exchange.
Intern Med 57(13):1935-1938,2018

43.Honda F, Tsuboi H, Toko H, Terasaki T, Terasaki M, Shimizu M, Ohyama A, Yagishita M, H, Takahashi H, Yokosawa M, Asashima H, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.
Contrast enhanced computed tomography revealed gallbladder hemorrhage due to active vasculitis in a patient with microscopic polyangiitis.
J Clin Rheumatol (in press)

44.Takahashi H, Tsuboi H, Umeda N, Toko H, Honda F, Ohyama A, Abe S, Yokosawa M, Asashima H, Hagiwara S, Kondo Y, Matsumoto I, Hirose Y, Hara A, Sumida T.:
A case of otitis media with ANCA-associated vasculitis accompanied with pituitary mass successfully treated by corticosteroids.
Modern Rheumatol Case Reports 2(2)185-190,2018

45.Sumida T, Azuma N, Moriyama M, Takahashi H, Asashima H, Honda F, Abe S, Ono Y, Hirota T, Hirata S, Tanaka Y, Shimizu T, Nakamura H, Kawakami A, Sano H, Ogawa Y, Tsubota K, Ryo K, Saito I,Tanaka A, Nakamura S, Takamura E, Tanaka M, Suzuki K, Takeuchi T, Yamakawa N, Mimori T, Ohta A, Nshiyama,S Yoshihara T, Suzuki Y, Kawano M, Tomiita M, Tsuboi H.:
Clinical practice guideline for Sjogren's syndrome 2017.
Mod Rheumatol 28(3):383-408,2018

46.Toko H, Tsuboi H, Umeda N, Honda F, Ohyama A, Takahashi H, Abe S, Yokosawa M, Asashima H, Hagiwara S, Hirota T, Kondo Y, Matsumoto I, Sumida T.:
A case of intractable hemophagocytic syndrome associated with systemic lupus erythematosus resistant to corticosteroids and intravenous cyclophosphamide that was successfully treated by cyclosporine A.
Intern Med 57(18):2747-2752,2018

47.Ohyama A, Tsuboi H, Noma H, Terasaki M, Shimizu M, Toko H, Honda F, Yagishita M, Takahashi H, Asasahima H, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
Associations between maternal clinical features and fetal outcomes in pregnancies of mothers with connective tissue diseases.
Mod Rheumatol (in press)

48.Shimizu M, Asashima H, Terasaki M, Toko H, Honda F, Ohyama A, Yagishita M, Takahashi H, Hagiwara S, Kondo Y, Tsuboi H, Matsumoto I, Sumida T.:
Renal sarcoidosis with multiple organ involvements.
J Clin Rheumatol (in press)

49.Kurata I, Tsubio H, Terasaki M, Shimizu M, Toko H, Honda F, Ohyama A, Yagishita M, Osada A, Kaneko S, Ebe H, Kawaguchi H, Takahashi H, Hagiwara S, Asashima H, Kondo Y, Matsumoto I, Sumida T.:
Effect of biological disease modifying anti-rheumatic drugs on airway and interstitial lung disease in patients with rheumatoid arthritis.
Intern Med 58(12):1703-1712,2019

50.Tsuboi H, Iizuka-Koga M, Asashima H, Takahashi H, Kudo H, Ono Y, Honda F, Iizuka A, Segawa S, Abe S, Yagishita M, Yokosawa M, Kondo Y, Moriyama M, Matsumoto I, Nakaramura S, Sumida T.
Up-regulation and pathogenic roles of CCL18-CCR8 axis in IgG4-related disease.
Mod Rheumatol (in press)

51.Hagiwara S, Tsuboi H, Terasaki T, Terasaki M, Toko H, Shimizu M, Honda F, Yagishita M, Ohyama A, Takahashi H, Yokosawa M, Asashima H, Kondo Y, Matsumoto I, Sumida T.:
Association of anti-cyclic citrullinated peptide antibody with clinical features in patients with psoriatic arthritis.
Mod Rheumatol (in press)

52.Kudo H, Tsuboi H, Asashima H, Takahashi H, Ono Y, Abe S, Honda F, Kondo Y, Wakasa Y, Takaiwa F, Takano M, Matsui M, Matsumoto I, Sumida T.:
Transgenic rice seeds expressing altered peptide ligands against the M3 muscarinic acetylcholine receptor suppress experimental sialadenitis-like Sjogren's syndrome.
Mod Rheumatol (in press)

53.Ono Y, Tsuboi H, Moriyama M, Asashima H, Kudo H, Takahashi H, Honda F, Abe S, Kondo Y, Takahashi S, Nakamura S, Matsumoto I, Sumida T.:
RORγt antagonist improves Sjogren's syndrome-like sialadenitis through downregulation of CD25.
Oral Dis. (in press)

54.Abe S, Tsuboi H, Kudo H, Asashima H, Ono Y, Honda F, Takahashi H, Yagishita M, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
Identification of M3 muscarinic acetylcholine receptor reactive Th17 cells in patients with primary Sjogren's syndrome.
JCI insight.(in press)

55.Shimizu M, Kondo Y, Tanimura R, Furuyama K, Yokosawa M, Asashima H, Tsuboi H, Matsumoto I, Sumida T.:
T-bet represses collagen-induced arthritis by suppressing Th17 lineage commitment through inhibition of RORgt expression and function.
Sci Rep (in press)