研究業績: 高橋 広行 (2014-2021)



1.Nakamagoe K, Shioya A, Yamaguchi T, Takahashi H, Koide R, Monzen T, Satoh J, Tamaoka A:
A Japanese case with Nasu-Hakola disease of DAP12 gene mutation exhibiting precuneus hypoperfusion.
Intern Med 50:2839-2844,2011

2.Ozaki T, Yamashita H, Kaneko S, Yorifuji H, Takahashi H, Ueda Y, Takahashi Y, Kaneko H, Kano T, Mimori A:
Cytomegalovirus disease of the upper gastrointestinal tract in patients with rheumatic diseases: a case series and literature review.
Clin Rheumatol 32:1683-1690,2013

3.Yamashita H, Eri T, Ueda Y, Ozaki T, Takahashi H, Tsuno T, Takahashi Y, Kano T, Mimori A: Diagnosis and treatment of primary Sjogren syndrome-associated peripheral neuropathy: a six-case series.
Mod Rheumatol 23:925-933,2013

4.Takahashi H, Yamashita H, Morooka M, Kubota K, Takahashi Y, Kaneko H, Kano T, Mimori A.:
The utility of FDG-PET/CT and other imaging techniques in the evaluation of IgG4-related disease. Joint Bone Spine.
Joint Bone Spine 81(4):331-6,2014

5.Hagiwara S, Tsuboi H, Hagiya C, Yokosawa M, Hirota T, Ebe H, Takahashi H, Ogishima H, Asashima H, Kondo Y, Umeda N, Suzuki T, Hitomi S, Matsumoto I, Sumida T.:
Pulmonary nocardiosis in patients with connective tissue disease: A report of two cases.
Intractable Rare Dis Res 3(1):25-28,2014

6.Yamashita H, Takahashi H, Kubota K, Ueda Y, Ozaki T, Yorifuji H, Bannai E, Minamimoto R, Morooka M, Miyata Y, Okasaki M, Takahashi Y, Kaneko H, Kano T, Mimori A: Utility of fluorodeoxyglucose positron emission tomography/computed tomography for early diagnosis and evaluation of disease activity of relapsing polychondritis: a case series and literature review.
Rheumatology (Oxford) 53:1482-1490,2014

7.Ebe H, Tsuboi H, Hagiya C, Takahashi H, Yokosawa M, Hagiwara S, Hirota T, Kurashima Y, Takai C, Miki H, Asashima H, Umeda N, Kondo Y, Ogishima H, Suzuki T, Chino Y, Matsumoto I, Sumida T.:
Clinical features of patients with IgG4-related disease complicated with perivascular lesions.
Mod Rheumatol 25(1):105-9,2015

8.Tsuboi H, Matsumoto I, Hagiwara S, Hirota T, Takahashi H, Ebe H, Yokosawa M, Hagiya C, Asashima H, Takai C, Miki H, Umeda N, Kondo Y, Ogishima H, Suzuki T, Hirata S, Saito K, Tanaka Y, Horai Y, Nakamura H, Kawakami A, Sumida T.:
Efficacy and safety of abatacept for patients with Sjogren's syndrome associated with rheumatoid arthritis. ROSE (Rheumatoid Arthritis with Orencia Trial toward Sjogren's syndrome Endocrinopathy) trial. An open label, one-year, prospective study. Interim analysis of 32 patients for 24 weeks.
Mod Rheumatol 25(2):187-93,2015

9.Yokosawa M, Tsuboi H, Nasu K, Hagiya C, Hagiwara S, Hirota T, Ebe H, Takahashi H, Asashima H, Kondo Y, Ogishima H, Suzuki T, Minami M, Bukawa H, Matsumoto I, Sumida T.:
Usefulness of MR imaging of the parotid glands in patients with secondary Sjogren’s syndrome associated with rheumatoid arthritis.
Mod Rheumatol 25(3):415-20,2015

10.Takahashi H, Tsuboi H, Kurata I, Takahashi H, Inoue S, Ebe H, Yokosawa M, Hagiwara S, Hirota T, Asashima H, Kaneko S, Kawaguchi H, Kurashima Y, Miki H, Umeda N, Kondo Y, Ogishima H, Suzuki T, Matsumoto I, Sumida T.:
Predictors of the response to treatment in acute lupus 1 hemophagocytic syndrome.
Lupus 24(7):659-68,2015

11.Takahashi H, Yamashita H, Kubota K, Miyata Y, Okasaki M, Morooka M, Takahashi Y, Kaneko H, Kano T, Mimori A:
Differences in fluorodeoxyglucose positron emission tomography/computed tomography findings between elderly onset rheumatoid arthritis and polymyalgia rheumatica.
Mod Rheumatol 25(4):546-51,2015

12.Takahashi H, Tsuboi H, Ogishima H, Yokosawa M, Takahashi H, Yagishita M, Abe S, Hagiwara S, Asashima H, Umeda N, Kondo Y, Suzuki T, Matsumoto I, Sumida T.:
[18F]fluorodeoxyglucose positron emission tomography/computed tomography can reveal subclinical prostatitis in a patient with IgG4-related disease.
Rheumatology (Oxford) 54(6):1113,2015

13.Asashima H, Tsuboi H, Takahashi H, Hirota T, Iizuka M, Kondo Y, Matsui M, Matsumoto I, Sumida T: The anergy induction of M3 muscarinic acetylcholine receptor-reactive CD4+ T cells suppresses experimental sialadenitis-like Sjogren's syndrome.
Arthritis Rheumatol 67:2213-2225,2015

14.Kurata I, Tsuboi H, Takahashi H, Yagishita M, Abe S, Ebe H, Takahashi H, Asashima H, Hirota T, Hagiwara S, Umeda N, Kondo Y, Ogishima H, Suzuki T, Matsumoto I, Sumida T.:
A case of relapsing neurosarcoidosis with brain nodules and hydrocephalus
successfully treated by corticosteroid and methotrexate.
Rheumatology (Oxford) 54(7):1160,2015

15.Hirota T, Suzuki T, Ogishima H, Hagiwara S, Ebe H, Takahashi H, Yokosawa M, Umeda N, Kondo Y, Tsuboi H, Matsumoto I, Sumida T.:
Evaluation of changes in magnetic resonance images following 24 and 52 weeks treatment of rheumatoid arthritis with infliximab, tocilizumab or abatacept.
Mod Rheumatol 26(1):29-35,2016

16.Takahashi H, Tsuboi H, Abe S, Yokosawa M, Hagiwara S, Asashima H, Hirota T, Umeda N, Kondo Y, Matsumoto I, Sumida T.:
Magnetic resonance imaging can reveal fascial vasculitis in a patient with microscopic polyangiitis.
Scand J Rheumatol 44(6):511-3,2015

17.Ueda Y, Tomoe H, Takahashi H, Takahashi Y, Yamashita H, Kaneko H, Kano T, Mimori A:
Interstitial cystitis associated with primary Sjogren's syndrome successfully treated with a combination of tacrolimus and corticosteroid: A case report and literature review.
Mod Rheumatol 26:445-449,2016.

18.Miki H, Tsuboi H, Kaneko S, Takahashi H, Yokosawa M, Asashima H, Hirota T, Hagiwara S, Umeda N, Kondo Y, Nishimura B, Sugano M, Matsumoto I, Sumida T.:
A case of refractory Kimura disease with a buccal bulky mass successfully treated with
low-dose cyclosporine A: report and review of the literature.
Allergol Int 65(2):212-4,2016

19.Tsuboi H, Matsumoto I, Hagiwara S, Hirota T, Takahashi H, Ebe H, Yokosawa M, Yagishita M, Takahashi H, Kurata I, Ohyama A, Honda F, Asashima H, Miki H, Umeda N, Kondo Y, Hirata S, Saito K, Tanaka Y, Horai Y, Nakamura H, Kawakami A, Sumida T.:
Effectiveness of abatacept for patients with Sjogren's syndrome associated with rheumatoid arthritis. An open label, multicenter, one-year, prospective study: ROSE (Rheumatoid Arthritis with Orencia Trial toward Sjogren's syndrome Endocrinopathy) trial.
Mod Rheumatol 26(6):891-899,2016

20.Hagiwara S, Tsuboi H, Honda F, Takahashi H, Kurata, I, Ohyama A, Yagishita M, Abe S, Kurashima Y, Kaneko S, Kawaguchi H, Takahashi H, Ebe H, Yokosawa M, Asashima H, Hirota T, Umeda N, Kondo Y, Matsumoto I, Sumida T.:
Association of anti-Ro/SSA antibody with response to biologics in patients with
rheumatoid arthritis.
Mod Rheumatol 26(6):857-862,2016

21.Hirota T, Tsuboi H, Iizuka-Koga M, Takahashi H, Asashima H, Yokosawa M, Kondo Y, Ohta M, Wakasa Y, Matsumoto I, Takaiwa F, Sumida T.:
Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of
glucose-6-phosphate-isomerase.
Mod Rheumatol 27(3):457-465,2017

22.Tahara M, Tsuboi H, Segawa S, Asashima H, Iizuka M, Hirota T, Takahashi H, Kondo Y, Matsui M, Matsumoto I, Sumida T.:
RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sjogren's syndrome-like sialadenitis.
Clin Exp Immunol 187(2):213-224,2017

23.Tsuboi H, Hagiwara S, Asashima H, Takahashi H, Hirota T, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Matsumoto I, Sumida T.:
Comparison of the performance of new ACR-EULAR classification criteria for primary Sjogren's syndrome with former sets of criteria in Japanese patients.
Ann Rheum Dis 76(12):1980-1985,2017

24.Iizuka-Koga M, Asashima H, Ando M, Lai C-Y, Mochizuki S, Nakanishi M, Nishimura T, Tsuboi H, Hirota T, Takahashi H, Masumoto I, Otsu M, Sumida T.:
Functional analysis of dendritic cells generated from T-iPS cells from CD4+ T cell clones of Sjogren's syndrome.
Stem Cell Reports 8(5):1155-1163,2017

25.Takahashi H, Tsuboi H, Asashima H, Hirota T, Kondo Y, Moriyama M, Matsumoto I, Nakamura S, Sumida T.:
cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjogren's syndrome.
Clin Exp Immunol190(1):96-109,2017

26.Takahashi H, Tsuboi H, Yokosawa M, Asashima H, Hirota T, Kondo Y, Matsumoto I, Sumida T.:
Diffusion-weighted magnetic resonance imaging of parotid glands before and after abatacept therapy in patients with Sjogren's syndrome associated with rheumatoid arthritis: Utility to evaluate and predict response to treatment.
Mod Rheumatol 28(2):300-307,2018

27.Kawaguchi H, Tsuboi H, Yagishita M, Terasaki T, Terasaki M, Shimizu M, Honda F, Ohyama A, Takahashi H, Miki H, Yokosawa M, Asashima H, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
A case of severe adult-onset Still disease with constrictive pericarditis and pleuritis successfully treated with tocilizumab in addition to corticosteroid and cyclosporin A.
Intern Med 57(7):1033-1038,2018

28.Yagishita M, Kondo Y, Terasaki T, Terasaki M, Shimizu M, Honda F, Oyama A, Takahashi H, Yokosawa M, Asashima H, Hagiwara S, Tsuboi H, Matsumoto I, Sumida T.
A case of clinically amyopathic dermatomyositis with interstitial pneumonia successfully treated with plasma exchange.
Intern Med 57(13):1935-1938,2018

29.Honda F, Tsuboi H, Toko H, Terasaki T, Terasaki M, Shimizu M, Ohyama A, Yagishita M, Takahashi H, Yokosawa M, Asashima H, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.
Contrast enhanced computed tomography revealed gallbladder hemorrhage due to active vasculitis in a patient with microscopic polyangiitis.
J Clin Rheumatol (in press)

30.Sumida T, Azuma N, Moriyama M, Takahashi H, Asashima H, Honda F, Abe S, Ono Y, Hirota T, Hirata S, Tanaka Y, Shimizu T, Nakamura H, Kawakami A, Sano H, Ogawa Y, Tsubota K, Ryo K, Saito I,Tanaka A, Nakamura S, Takamura E, Tanaka M, Suzuki K, Takeuchi T, Yamakawa N, Mimori T, Ohta A, Nshiyama,S Yoshihara T, Suzuki Y, Kawano M, Tomiita M, Tsuboi H.:
Clinical practice guideline for Sjogren's syndrome 2017.
Mod Rheumatol 28(3):383-408,2018

31.Ohyama A, Tsuboi H, Noma H, Terasaki M, Shimizu M, Toko H, Honda F, Yagishita M, Takahashi H, Asasahima H, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
Associations between maternal clinical features and fetal outcomes in pregnancies of mothers with connective tissue diseases.
Mod Rheumatol (in press)

32.Shimizu M, Asashima H, Terasaki M, Toko H, Honda F, Ohyama A, Yagishita M, Takahashi H, Hagiwara S, Kondo Y, Tsuboi H, Matsumoto I, Sumida T.:
Renal sarcoidosis with multiple organ involvements.
J Clin Rheumatol (in press)

33.Mimura T, Kondo Y, Ohta A, Iwamoto M, Ota A, Okamoto N, Kawaguchi Y, Kono H, Takasaki Y, Takei S, Nishimoto N, Fujimoto M, Funakubo-Asanuma Y, Mimori A, Okiyama N, Kaneko S, Takahashi H, Yokosawa M, Sumida T.:
Evidence-based clinical practice guideline for adult Still's disease.
Mod Rheumatol 28(5):736-757,2018

34.Kurata I, Tsubio H, Terasaki M, Shimizu M, Toko H, Honda F, Ohyama A, Yagishita M, Osada A, Kaneko S, Ebe H, Kawaguchi H, Takahashi H, Hagiwara S, Asashima H, Kondo Y, Matsumoto I, Sumida T.:
Effect of biological disease modifying anti-rheumatic drugs on airway and interstitial lung disease in patients with rheumatoid arthritis.
Intern Med 58(12):1703-1712,2019

35.Tsuboi H, Iizuka-Koga M, Asashima H, Takahashi H, Kudo H, Ono Y, Honda F, Iizuka A, Segawa S, Abe S, Yagishita M, Yokosawa M, Kondo Y, Moriyama M, Matsumoto I, Nakaramura S, Sumida T.:
Up-regulation and pathogenic roles of CCL18-CCR8 axis in IgG4-related disease.
Mod Rheumatol (in press)

36.Hagiwara S, Tsuboi H, Terasaki T, Terasaki M, Toko H, Shimizu M, Honda F, Yagishita M, Ohyama A, Takahashi H, Yokosawa M, Asashima H, Kondo Y, Matsumoto I, Sumida T.:
Association of anti-cyclic citrullinated peptide antibody with clinical features in patients with psoriatic arthritis.
Mod Rheumatol (in press)

37.Tsuboi H, Honda F, Takahashi H, Ono Y, Abe S, Kondo Y, Matsumoto I, Sumida T.:
Pathogenesis of IgG4-related disease. Comparison with Sjogren's syndrome.
Mod Rheumatol (in press)

38.Kudo H, Tsuboi H, Asashima H, Takahashi H, Ono Y, Abe S, Honda F, Kondo Y, Wakasa Y, Takaiwa F, Takano M, Matsui M, Matsumoto I, Sumida T.:
Transgenic rice seeds expressing altered peptide ligands against the M3 muscarinic acetylcholine receptor suppress experimental sialadenitis-like Sjogren's syndrome.
Mod Rheumatol (in press)

39.Sato R, Takahashi H, Terasaki M, Okamoto S, Terasaki T, Toko H, Yagishita M, Hagiwara S, Kondo Y, Tsuboi H, Matsumoto I, Sumida T.:
Advantage of magnetic resonance imaging in detecting tracheal involvement and evaluation of the therapeutic effect in relapsing polychondritis with asthma-like symptoms.
J Clin Rheumatol (in press)

40.Terasaki M, Takahashi H, Sato R, Okamoto S, Terasaki T, Toko H, Yagishita M, Hagiwara S, Kondo Y, Tsuboi H, Matsumoto I, Sumida T.:
Successful treatment with multitarget therapy of mycophenolate mofetil and tacrolimus for cyclophosphamide-resistant ANCA-associated pauci-immune glomerulonephritis developed independently of systemic lupus erythematosus.
J Clin Rheumatol (in press)

41.Nishiyama T, Kondo Y, Okamoto S, Terasaki M, Toko H, Yagishita M, Takahashi H, Yokosawa M, Tsuboi H, Matsumoto I, Sumida T.:
Aortic arch aneurysm in Behcet disease successfully treated with infliximab.
Intern Med (in press)

42.Ono Y, Tsuboi H, Moriyama M, Asashima H, Kudo H, Takahashi H, Honda F, Abe S, Kondo Y, Takahashi S, Nakamura S, Matsumoto I, Sumida T.:
RORγt antagonist improves Sjogren's syndrome-like sialadenitis through downregulation of CD25.
Oral Dis (in press)

43.Okamoto S, Tsuboi H, Sato R, Terasaki T, Toko H, Shimizu M, Honda F, Yagishita M, Ohyama A, Kurata I, Abe S, Takahashi H, Osada A, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
IgG4-related pleural disease with aortitis and submandibular glands involvement successfully treated with corticosteroid: case-based review.
Rheumatol Int (in press)

44.Abe S, Tsuboi H, Kudo H, Asashima H, Ono Y, Honda F, Takahashi H, Yagishita M, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
Identification of M3 muscarinic acetylcholine receptor reactive Th17 cells in patients with primary Sjogren's syndrome.
JCI insight (in press)

45.Terasaki T, Kondo Y, Takahashi M, Tawara T, Fujita A, Yagi H, Kawai H, Noguchi M, Sato R, Terasaki M, Okamoto S, Toko H, Yagishita M,
Takahashi H, Hagiwara S, Tsuboi H, Matsumoto I, Sumida T.:
Therapeutic plasma exchange improved pregnancy-associated thrombotic microangiopathy but not pregnancy outcome in patient with systemic lupus erythematosus.
Intern Med (in press)

46.Yagishita M, Tsuboi H, Tabuchi D, Sugita T, Nishiyama T, Okamoto S, Terasaki T, Shimizu M, Honda F, Ohyama A, Kurata I, Abe S, Takahashi H, Osada A, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
Clinical features and prognosis of nocardiosis in patients with connective tissue diseases.
Mod Rheumatol (in press)

47.Morinaka S, Tsuboi H, Hagiwara S, Sugita T, Tabuchi D, Sato R, Nishiyama T, Okamoto S, Terasaki T, Yagishita M, Takahashi H, Kondo Y, Matsumoto I, Sumida T.:
Clinical features of large vessel vasculitis (LVV): Elderly-onset versus young-onset.
Mod Rheumatol (in press)

48.Nishiyama T, Kondo Y, Tsuboi H, Noma H, Tabuchi D, Sugita T, Okamoto S, Terasaki T, Shimizu M, Honda F, Ohyama A, Kurata I, Yagishita M, Abe S, Takahashi H, Osada A, Hagiwara S, Matsumoto I, Sumida T.:
QTc interval prolongation in patients with systemic lupus erythematosus treated with hydroxychloroquine.
Mod Rheumatol (in press)

49.Takahashi H, Tsuboi H, Abe S, Honda F, Kondo Y, Matsumoto I, Sumida T.:
Humanized NOD/SCID/IL2rγnull mice exhibit functionally augmented human regulatory T cells associated with enzymatic upregulation of H3K27me3 in comparison with humans.
Clin Exp Immunol (in press)

50.Okamoto S, Tsuboi H, Noma H, Tabuchi D, Sugita T, Nishiyama T, Terasaki T, Shimizu M, Honda F, Yagishita M, Ohyama A, Kurata I, Abe S, Takahashi H, Osada A, Hagiwara S, Kondo Y, Matsumoto I, Sumida T.:
Predictive factors for pneumomediastinum during management of connective tissue diseaserelated interstitial lung disease: A retrospective study.
Intern Med (in press)

51.Honda F, Tsuboi H, Ono Y, Abe S, Takahashi H, Ito K, Yamada K, Kawano M, Kondo Y, Asano K, Tanaka M, Mallsen M, Mallsen B, Matsumoto I, Sumida T.:
Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis.
Arthritis Res Ther (in press)