The International Symposium ‘Molecular basis of host cell competency in virus infection’ 2014
granted by Grant-in-Aid for Scientific Research on Innovative Areas.

Dynamic interplay between viruses and their hosts

November 8 (Sat)

• 11:00-12:00 Generalization Group Meeting
• 13:20: Opening remark
• 13:30-15:50 Session 1 : Innate immunity to viral infections (Chairs: Takashi Fujita & Satoshi Koike)
  • Adolfo Garcia-Sastre (Icahn School of Medicine at Mount Sinai, New York, USA)
    Induction and regulation of antiviral innate signaling.
  • Mitsutoshi Yoneyama (Medical mycology Research Center, Chiba University)
    Regulation of antiviral innate immunity by the host RNA binding proteins.
  • Peter Staeheli (Institute for Virology University Medical Center Freiburg, Freiburg, Germany)
    Uncovering the role of interferon-λ in antiviral defense.
  • Umeharu Ohto （Graduate School of Pharmaceutical Sciences, The University of Tokyo.）
    Structural study of Toll-like receptor 8 recognizing viral single stranded RNA.
• 16:10-17:55 Session 2: New approaches for virus research (Chairs: Tohru Natsume & Hisashi Arase)
  • Takeshi Noda (Institute of Medical Science, University of Tokyo & JST, PRESTO)
    Packaging of the influenza A virus ribonucleoproein complexes.
  • Louis J. Picker (Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA)
    Cytomegalovirus Vectors: A New Immunology from a Very Old Virus.
  • Kyosuke Nagata (Nagata Special Laboratory, Faculty of Medicine, University of Tsukuba)
    From the molecular mechanism of influenza virus genome replication and transcription to the influenza virus control.
• 18:30: Party

November 9 (Sun)

• 9:10-11:30 Session 3: Viral pathogenesis and treatment (Chairs: Akinori Takaori & Yusuke Yanagi)
  • Takaji Wakita (Department of Virology II, National Institute of Infectious Diseases)
    Regulation of viral lifecycle in hepatitis C virus infection.
  • Richard K. Plemper (Institute for Biomedical Sciences, Georgia State University)
    Insights from the Measles Virus System Illuminate Paramyxovirus Entry and Highlight Druggable Targets for Anti-Paramyxovirus Therapy.
  • Akihisa Kato (Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo)
    Central nervous system specific virulence of herpes simplex virus 1 involves phosphorylation of a viral dUTPase by a viral protein kinase.
  • Warner Greene (Gladstone Institute of Virology and Immunology, Medicine and of Microbiology and Immunology, University of California, San Francisco, USA)
    HIV/AIDS and the Death of CD4 T cells: A Little Murder and a Lot of Suicider.
• 13:00-14:45 Session 4 : Viral evolution and mathematical models (Chairs: Yoshio Koyanagi & Hideo Iba)
  • Akira Sasaki (Department of Evolutionary Studies of Biosystems, The Graduate University for Advanced Studies)
    Coevolutionary dynamics of human antiviral protein APOBEC3G and its viral antagonist Vif.
  • Raul Andino (Microbiology and Immunology, University of California, San Francisco, USA)
    RNA virus population dynamics and the mechanisms of replication and adaptation.
  • Shuhei Miyashita & Masayuki Ishikawa (Plant-Microbe Interactions Research Unit, National Institute of Agrobiological Sciences)
    Mathematical modeling of positive-strand RNA virus infection in single cells reveals a sophisticated adaptation system of the viruses.