町野（講師）
論文発表
2021年度

1. Machino T, Aonuma K, Komatsu Y, Yamasaki H, Igarashi M, Nogami A, Ieda M. Dry textile electrode for ambulatory monitoring after catheter ablation of atrial fibrillation: A pilot study of simultaneous comparison to the Holter electrocardiogram. F1000Research. 2022;97.
2. Hattori M, Komatsu Y, Naeemah QJ, Hanaki Y, Ichihara N, Ota C, Machino T, Kuroki K, Yamasaki H, Igarashi M, Aonuma K, Nogami A, Ieda M. Rotational Activation Pattern During Functional Substrate Mapping: Novel Target for Catheter Ablation of Scar-Related Ventricular Tachycardia. Circulation Arrhythmia Electrophysiol. 2022;15:e010308.
3. Machino T, Sato A, Murakoshi N, Ieda M. Phase I investigator-initiated study of the safety of MTC001 in patients with chronic ischemic heart failure. Medicine. 2021;100:e28372.
4. Kato H, Watanabe H, Koike A, Wu L, Hayashi K, Konno H, Machino T, Nishi I, Sato A, Kawamoto H, Aonuma K, Sankai Y, Ieda M. Effects of Cardiac Rehabilitation With Lumbar-Type Hybrid Assistive Limb on Muscle Strength in Patients With Chronic Heart Failure　― A Randomized Controlled Trial ―. Circ J. 2021;86:60-67.
5. Ishihara S, Machino T, Deguchi K, Ohki S, Mogami Y, Tansho M, Shimizu T, Hill JP, Yamauchi Y, Iyi N. Disposable Nitric Oxide Generator Based on a Structurally Deformed Nitrite-Type Layered Double Hydroxide. Inorg Chem. 2021;60:16008-16015.

2020年度

1. Ishihara S, Machino T, Deguchi K, Ohki S, Mogami Y, Tansho M, Shimizu T, Hill JP, Yamauchi Y, Iyi N. Disposable Nitric Oxide Generator Based on a Structurally Deformed Nitrite-Type Layered Double Hydroxide. Inorg Chem. 2021
2. Yamasaki H, ..., Machino T, et al. Durability of the Isolated Area after the Antrum Pulmonary Vein Isolation Using the Radiofrequency Hot-Balloon Catheter. The 83rd Annual Scientific Meeting of the Japanese Circulation Society, 2021.
3. Igarashi M, ..., Machino T, et al. Acute and long-term results of bipolar radiofrequency catheter ablation of refractory ventricular arrhythmias of deep intramural origin. Heart Rhythm. 2020
4. Hanaki Y, ..., Machino T, et al. Preprocedural restoration of sinus rhythm and left atrial strain predict outcomes of catheter ablation for long-standing persistent atrial fibrillation. Journal of Cardiovascular Electrophysiology. 2020.
5. 渡邉 真哉, ..., 町野 毅, 他. 膠芽腫を対象とした第II相試験で設定される有効性エンドポイントの近年の傾向に関する調査研究. 医薬品レギュラトリーサイエンス2021

2019年度

1. Machino-Ohtsuka T, Seo Y, Ishizu T, Yamamoto M, Hamada-Harimura Y, Machino T, Yamasaki H, Sekiguchi Y, Nogami A, Aonuma K, Ieda M. Relationships between maintenance of sinus rhythm and clinical outcomes in patients with heart failure with preserved ejection fraction and atrial fibrillation. Journal of Cardiology. 2019;74(3):235-244.
2. Adachi T, Sato A, Kuroki K, Terai T, Hanaoka D, Hiraya D, Machino T, Nogami A, Ieda M, Aonuma K. Audiovisual telesupport system for cardiovascular catheter interventions: A preliminary report on the clinical implications. Catheter Cardiovasc Interv. 2019;1:219–
3. Yamasaki H, Aonuma K, Shinoda Y, Komatsu Y, Masuda K, Hashimoto N, Sai E, Yamagami F, Okabe Y, Tsumagari Y, Hanaki Y, Watanabe H, Machino T, Kuroki K, Sekiguchi Y, Nogami A, Ieda M. Initial Result of Antrum Pulmonary Vein Isolation Using the Radiofrequency Hot-Balloon Catheter With Single-Shot Technique. JACC Clin Electrophysiol. 2019;5(3):354-363.
4. Yui Y, Sekiguchi Y, Nogami A, Yamasaki H, Machino T, Kuroki K, Igarashi M, Aonuma K, Ieda M. Midterm outcomes of catheter ablation for atrial fibrillation in patients with cardiac tamponade. Journal of Arrhythmia. 2019;35(1):109-120.
5. Yamasaki H, Yamagami F, Machino T, Kuroki K, Sekiguchi Y, Aonuma K, Nogami A. Perforation of the Left Atrial Appendage Caused by Inadvertent Deployment of a Soft J-Tipped Guidewire During Radiofrequency Hot-Balloon Ablation. Circ J. 2018;82(5):1476-1477.
6. Kuroki K, Nogami A, Igarashi M, Masuda K, Kowase S, Kurosaki K, Komatsu Y, Naruse Y, Machino T, Yamasaki H, Xu D, Murakoshi N, Sekiguchi Y, Aonuma K. New Substrate-Guided Method of Predicting Slow Conducting Isthmuses of Ventricular Tachycardia: Preliminary Analysis to the Combined Use of Voltage Limit Adjustment and Fast-Fourier Transform Analysis. Circ Arrhythm Electrophysiol. 2018;11(4):e005705.
7. Igarashi M, Nogami A, Kurosaki K, Hanaki Y, Komatsu Y, Fukamizu S, Morishima I, Kaitani K, Nishiuchi S, Talib AK, Machino T, Kuroki K, Yamasaki H, Murakoshi N, Sekiguchi Y, Kuga K, Aonuma K. Radiofrequency Catheter Ablation of Ventricular Tachycardia in Patients With Hypertrophic Cardiomyopathy and Apical Aneurysm. JACC Clin Electrophysiol. 2018;4(3):339-350.
8. Komatsu Y, Nogami A, Shinoda Y, Masuda K, Machino T, Kuroki K, Yamasaki H, Sekiguchi Y, Aonuma K. Idiopathic Ventricular Arrhythmias Originating From the Vicinity of the Communicating Vein of Cardiac Venous Systems at the Left Ventricular Summit. Circ Arrhythm Electrophysiol. 2018;11(1):e005386.

学会発表
2021年度

1. Machino T, Sato A, Murakoshi N, Aonuma K, Ieda M. A Multipolar Mapping and Injection Catheter for Transendocardial Cell Therapy. 第86回日本循環器学会学術集会, 2022-03-13（オンライン）
2. 町野 毅. 医療イノベーション！アカデミアがリードするエコシステム、Tsukuba Connect #17, 2021-04-16（つくば）
3. 町野 毅. 医療イノベーションのネットワークを発展させるためには？、Research Studio Catapult, 2022-01-29（東京）
4. 町野 毅. First-in-Humanの再生医療医師主導治験．AMED革新的医療技術創出拠点令和3年度成果報告会、2022-02-22（東京）

2020年度

1. 町野 毅, 佐藤 明, 村越 伸行, 家田 真樹. ブタ心筋梗塞モデルにおけるVCAM-1陽性心臓線維芽細胞の経カテーテル心筋内投与による心機能改善効果. 第20回日本再生医療学会総会，
2. 町野 毅. 医療イノベーション！アカデミアがリードするエコシステム. Tsukuba Connect, つくば，2021（招待講演）
3. Machino T. Startup Pitch. Research Studio powered by SPARK 2020 International Symposium, Tokyo, 2020（国際シンポジウム座長）
4. 渡邉真哉, 小栁智義, 町野 毅, 他. PMDA審査員経験を生かした研究成果の事業化支援：筑波大学T-CReDOにおける橋渡し研究及び起業家育成教育. 第79回日本脳神経外科学会総会, 2020.
5. 渡邉真哉, 野中孝浩, 前田 誠, 野口裕史, 小栁智義, 町野 毅, 他. 近年の膠芽腫を対象とした第II相試験で設定される有効性指標に関する実態調査. 第10回レギュラトリーサイエンス学会, 2020.

2019年度

1. Murakoshi N, Isaka Y, Machino T, et al. Targeted genetic analysis for patients with left ventricular dysfunction complicated with arrhythmias using next-generation sequencing. 第82回日本循環器学会
2. Tsumagari Y, MachinoT, et al. Head-to-head Comparison of Warfarin versus DOAC for the Prevalence of Left Atrial Appendage Thrombi in Patients with Nonvalvular Atrial Fibrillation. 第82回日本循環器学会
3. Hanaki Y, Machino T, et al. Impact of sinus rhythm restoration prior to catheter ablation for long-standing persistent atrial fibrillation on procedural outcome: a comparison by propensity score analysis. 第82回日本循環器学会
4. Adachi T, Sato A, Kuroki K, Machino T, et al. Audiovisual telementoring system for cardiovascular catheter intervention. European Society of Cardiology Congress 2018
5. Machino T, Ishii K, et al. Near-infrared spectroscopy demonstrated a heart rate-dependent decrease in cerebral oxygenation during paroxysmal supraventricular tachycardia as well as ventricular tachycardia. European Society of Cardiology Congress 2018（Best Poster受賞）
6. 佐藤明、安達享、平谷太吾、町野毅、他．遠隔映像配信システムを用いた僻地における心臓カテーテル治療に対する遠隔治療補助システムの構築．第66回日本心臓病学会
7. 町野毅．橋渡し研究における医療アントレプレナー教育（Research Studio 2018 powered by SPARK）．第7回　筑波大学・東京理科大学 合同リトリート（招待講演）
8. Murakoshi N, Kida M, Watanabe Y, Machino T, et al. Direct Injection of Vascular Cell Adhesion Molecule-1-positive Cardiac Fibroblasts Improves Cardiac Dysfunction after Myocardial Infarction．第83回日本循環器学会
9. Machino T, et al. Detection of Atrial Fibrillation with Conductive Textile Electrodes: a pilot validation study for medical application. 第83回日本循環器学会
10. Machino T, et al. Conductive Textile Electrodes for continuous wearable monitoring: a pilot study for detection of atrial fibrillation after catheter ablation．第66回日本不整脈心電学会

研究費

1. 自家心臓線維芽細胞による心不全患者に対する再生医療のfirst-in-human臨床試験, AMED再生医療実用化研究事業（2021-2023年度）

特許

1. Koiso T, Hoshida A, Yoshinuma M, Mori K, Machino T, Sato A, Murakoshi N. Drug solution injection needle and drug solution injection needle system. WO/2021/192283. 2021-09-30.
2. Koiso T, Hoshida A, Machino T, Sato A, Murakoshi N. Drug solution injection needle system. WO/2021/192284. 2021-09-30.
3. Koiso T, Mori K, Machino T, Sato A, Murakoshi N. Liquid medicine injection needle and liquid medicine injection system. WO/2021/192285. 2021-09-30.

山田（講師）
論文発表
2021年度

1. Kaneko T, Doki K, Yamada T, Niisato Y, Homma M. Distribution of bevacizumab into ascites decreases the serum drug exposure: A case of metastatic colon cancer. Therapeutic Drug Monitoring. Vol 43,813-814,2021.
2. Hirose S, Enami C, Kawamatsu N, Ito Y, Onoda T, Sugiyama Y, Suzuki H, Nagafuchi M, Ikeda T, Nisato Y, Yamada T, Yamamoto Y, Moriwaki T, Suzuki H. Systemic chemotherapy combined with anti-epidermal growth factor receptor antibody therapy for RAS wild-type appendiceal signet-ring cell carcinoma: A series of three cases. Int Cancer Conference Journal accepted 2021.
3. Minashi K, Yamada T, Hosaka H, Amagai K, Shimizu Y, Kiyozaki H, Sato M, Soeda A, Endo S, Ishida H, Kamoshida T, Sakai Y, Shitara K. Cancer-related FGFR2 overexpression and gene amplification in Japanese patients with gastric cancer. JJCO Vol 51(10):1523-33, 2021
4. Ogawa K, Ishikawa H, Hisakura K, Hiroshima Y, Moriwaki T, Yamamoto Y, Yamada T, Akashi Y, Owada Y, Ohara Y, Enomoto T, Sakurai H, Oda T. Retrospective analysis of neoaduvant chemotherapy followed by surgery versus definitive chemoradhiotyerapy with proton beam for locally advanced esophageal squamous cell carcinoma. IJCO Vol 26(10),1856-63, 2021

2020年度

1. Nakamura Y, Ishitsuka Y, Sasaki K, Ishizuki S, Tanaka R, Okiyama N. Furuta J, Yamada T, Fujisawa Y. A prospective, phase II study on the safety and efficacy of negative pressure closure for the stabilization of split-thickness skin graft in large or muscle-exposing defects: the NPSG study. Journal of Dermatology 2021 doi: 10.1111/1346-8138.15970.
2. Nakamura K, Marushima A, Takahashi Y, Kimura A, Asami M, Egawa S, Kaneko J, Kondo Y, Yonekawa C, Hoshiyama E, Yamada T, Maruo K, Inoue Y, IENE ECT with LIFE study group.　Levetiracetam versus fosphenytoin as second line treatment after diazepam for status epilepticus: study protocol for a multicenter non-inferiority designed randomized control trial. Trials 2021 doi: 10.1186/s13063-021-05269-7.
3. Nakamagoe K, Yamada T, Okune S, Moriwaki T, Tamaoka A. Fisher syndrome as immune-related adverse events after using pembrolizumab but not nivolumab. Acta Neurologica Belgica 2021 doi: 10.1007/s13760-021-01623-3.
4. Moriwaki T, Gosho M, Sugaya A, Yamada T, Yamamoto Y, Hyodo I. Optimal Maintenance Strategy for First-Line Oxaliplatin-Containing Therapy with or without Bevacizumab in Patients with Metastatic Colorectal Cancer: A Meta-Analysis Cancer Res Treat. 2020 doi: 10.4143/crt.2020.805.
5. Suzuki H, Yamada T, Sugaya A, Ueyama , Yamamoto Y, Moriwaki T, Hyodo I. Retrospective analysis for the efficacy and safety of nivolumab in advanced gastric cancer patients according to ascites burden International Journal of Clinical Oncology Vol26, 370, 2020..
6. Shinozaki K, Yamada T, Nasu J, Matsumoto T, Yiasa Y, Shiraishi T, Nagano H, Moriyama I, Fujiwara T, Miguchi M, Yoshida R, Nozaka K, Tanioka H, Nagasaka T, Kurisu Y, Kobayashi M, Tsuchihashi K, Inukai M, Kikuchi Y, Nishina T. A phase II study of FOLFOXIRI plus Bevacizumab as initial chemotherapy for patients with untreated metastatic colorectal cancer: TRICC1414 (BeTRI).　 International Journal of Clinical Oncology Vol26, 399, 2020.
7. Takayama T, Suzuki H, Okada K, Yamada T, Maruo K, Saito Y, Mizokami Y. Prediction of true Helicobacter pylori-uninfected status using a combination of age, serum antibody and pepsinogen: Logistic regression analysis PLoS One Vol 15, e0240040, 2020
8. Yatsuda Y, Hirose S, Ito Y, Onoda T, Sugiyama T, Nagafuchi M, Suzuki H, Nisato Y, Tange Y, Ikeda T, Yamada T, Yamamoto Y, Osawa M, Sakamoto N, Moriwaki T, Mizokami Y. Successful long-term durable response after discontinuation of nivolumab in advanced gastric cancer patients: A case report　Internal Medicine　2020 Vol60, 1011-1017, 2021
9. 関根郁夫, 鈴木敏夫, 山田武史, 鈴木英雄　臨床研究の進め方　肺癌2020;60:292-297.
10. Araki R, Yamada T, Maruo K, Araki A, Miyakawa R, Suzuki H, Hashimoto K. Gamma-Polyglutamic Acid-Rich Natto Suppresses Postprandial Blood Glucose Response in the Early Phase after Meals: A Randomized Crossover Study Nutrients Vol 12, 2374, 2020
11. Kito Y, Satake H, Taniguchi H, Yamada T, Horie Y, Esaki T, Denda T, Yasui H, Izawa N, Masuishi T, Moriwaki T, Mori K, Yamazaki K. Phase Ib study of FOLFOXIRI plus ramucirumab as first-line treatment for patients with metastatic colorectal cancer Cancer Chemotherapy and Pharmacology. Vol 86, 277-284, 2020
12. Hirose S, Kaneko T, Yamaura M, Nagase M, Akutsu D, Yamada T, Narasaka T, Sakamoto N, Mizokami Y. A case report: inflammatory myofibroblastic tumor of ileum with intussusception in adult. Clinical Journal of Gastroenterology Vol.13,1116-1120, 2020
13. Hirose S, Moriwaki T, Yamaura M, Suganuma D, Tajima H, Sato M, Enami C, Yamada T, Yamamoto Y, Sakamoto N, Hyodo I. A case of advanced gastric cancer showing HER2 positivity after chemotherapy International Cancer Conference Journal Vol 9, 112-115, 2020

2019年度

1. Sato Y, Yamada T, Hiroyama T, Sudo K, Hasegawa N, Hyodo I, Nakamura Y. A robust culture method for maintaining tumorigenic cancer stem cells in the hepatocellular carcinoma cell line Li-7. Cancer Science Vol110, 1644-1652, 2018
2. Imanishi M, Yamamoto Y, Hamano Y, Yamada T, Moriwaki T, Gosho M, Okumura T, Boku N, Kondo H, Hyodo I. Efficacy of adjuvant chemotherapy after resection of pulmonary metastasis from colorectal cancer: a propensity scoreematched analysis. Eur J Cancer Vol.106, 69-77, 2019
3. Hamano Y, Moriwaki T, To K, Watahiki T, Yamada T, Shingo Sakashita, Ichinosuke Hyodo. A neuroendocrine tumor of unknown primary origin that responded to treatment based on tumor grade progression: a case report. Internal Medicine Vol 58, 1087-1091, 2018.
4. Yamaura M, Yamada T, Watanabe R, Kawai H, Hirose S, Tajima H, Sato M, Uchida Y, Suganuma D, Yamamoto Y, Moriwaki T, Hyodo I. Anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease, successfully treated with modified FOLFOX6: a case report. BMC Cancer Vol.18, 1142, 2018. (Corresponding author)

学会発表
2021年度

1. Ueyama Shunsuke, Yamada Takeshi, et al. Real World Data on Immune Checkpoint Inhibitors as Later Line Treatment for Esophageal Cance JSMO2021
2. Sawafuji Taku, Yamada Takeshi, et al. Efficacy and safety of cabozantinib in patients with advanced hepatocellular carcinoma: a retrospective analysis JSMO2021
3. 山田 武史、他　筑波大学附属病院における診療科ヒアリングによる臨床研究推進の試み　ARO協議会　第8回学術集会
4. 石川直樹; 山田武史、他　ペムブロリズマブによる免疫関連有害事象(irAE)大腸炎に対してサラゾスルファピリジンが著効した1例　第365回日本消化器病学会関東支部例会/2021-07-10

2020年度

1. Suguru　H, Yamada　T, et al. A retrospective study to evaluate safety and efficacy of concurrent chemoradiotherapy with FOLFOX for esophageal cancer. JSMO 2020

2019年度

1. 山田武史、他　筑波大学における特定臨床研究の促進策の現状と課題　2019年9月28日　第7回ARO協議会
2. Suzuki　H, Yamada　T, et al. Retrospective analysis for efficacy and safety of Nivolumab in advanced gastric cancer patients with malignant ascites. JSMO 2019
3. Yamada T. Oncolytic virotherapy of HCC: Pros and cons. The 3rd MYONGJI INTERNATIONAL LIVER SYMPOSIUM, Korea. 2018 Sep 7th Session 5.

松阪（教授）
論文発表
2022年度

1. Kozuka M, Battaglin F, Jayachandran P, Wang J, Arai H, Soni S, Zhang W, Hirai M, Matsusaka S, Lenz HJ. Clinical significance of circulating tumor cell induced epithelial-mesencymal transition in patients with metastatic colorectal cancer by single-cell RNA-sequencing. Cancers (Basel). 13(19):4862. doi: 10.3390/cancers13194862. 2021.
2. El-Sedek IA, Miyazawa A, Shen LT, Makita S, Mukherjee P, Lichtenegger A, Matsusaka S, Yasuno Y. Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation. Biomed Opt Express. 12(11): 6844-6863, 2021.
3. Seesan T, Abd El-Sadek I, Mukherjee P, Zhu L, Oikawa K, Miyazawa A, Shen LT, Matsusaka S, Buranasiri P, Makita S, Yasuno Y. Deep convolutional neural network-based scatterer density and resolution estimators in optical coherence tomography. Biomed Opt Express. 13(11): 168-183, 2021.
4. Suenaga M, Cao S, Zhang W, Matsusaka S, Okazaki S, Berger MD, Miyamoto Y, Schirripa M, Barzi A, Yamamoto N, Yamaguchi T, Lenz HJ. Role of enterocyte-specific gene polymorphisms in response to adjuvant treatment for stage III colorectal cancer. Pharmacogenet Genomics. 31(1): 10-16, 2021.

2020年度

1. Matsusaka S, Hanna DL, Ning Y, Yang D, Cao S, Berger MD, Miyamoto Y, Suenaga M, Dan S, Mashima T, Seimiya H, Zhang W, Lenz HJ. Epidermal growth factor receptor mRNA expression: A potential molecular escape mechanism from regorafenib. Cancer Sci. 111(2): 441-450, 2020.
2. Mikami H, Kawaguchi M, Huang CJ, Matsumura H, Sugimura T, Huang K, Lei C, Ueno S, Miura T, Ito T, Nagasawa K, Maeno T, Watarai H, Yamagishi M, Uemura S, Ohnuki S, Ohya Y, Kurokawa H, Matsusaka S, Sun CW, Ozeki Y, Goda K. Virtual-freezing fluorescence imaging flow cytometry. Nat Commun. 11(1): 1162, 2020.
3. Nitta N, Iino T, Isozaki A, Yamagishi M, Kitahama Y, Sakuma S, Suzuki Y, Tezuka H, Oikawa M, Arai F, Asai T, Deng D, Fukuzawa H, Hase M, Hasunuma T, Hayakawa T, Hiraki K, Hiramatsu K, Hoshino Y, Inaba M, Inoue Y, Ito T, Kajikawa M, Karakawa H, Kasai Y, Kato Y, Kobayashi H, Lei C,Matsusaka S, Mikami H, Nakagawa A, Numata K, Ota T, Sekiya T, Shiba K, Shirasaki Y, Suzuki N, Tanaka S, Ueno S, Watarai H, Yamano T, Yazawa M, Yonamine Y, Di Carlo D, Hosokawa Y, Uemura S, Sugimura T, Ozeki Y, Goda K. Raman image-activated cell sorting. Nat Commun. 11(1): 3452, 2020.
4. Isozaki A, Nakagawa Y, Loo MH, Shibata Y, Tanaka N, Setyaningrum DL, Park JW, Shirasaki Y, Mikami H, Huang D, Tsoi H, Riche CT, Ota T, Miwa H, Kanda Y, Ito T, Yamada K, Iwata O, Suzuki K, Ohnuki S, Ohya Y, Kato Y, Hasunuma T,Matsusaka S, Yamagishi M, Yazawa M, Uemura S, Nagasawa K, Watarai H, Di Carlo D, Goda K. Sequentially addressable dielectrophoretic array for high-throughput sorting of large-volume bioliogical compartments. Sci Adv. 6(22): eaba6712, 2020.
5. Suenaga M, Cao S, Zhang W, Matsusaka S, Okazaki S, Berger MD, Miyamoto Y, Schirripa M, Barzi A, Yamamoto N, Yamaguchi T, Lenz HJ*. Role of enterocyte-specific gene polymorphisms in response to adjuvant treatment for stage III colorectal cancer. Pharmacogenet Genomics. Doi: 10.1097/FPC, 2020.
6. Sonoda T, Yanagitani N, Suga K, Yoshizawa T, Nishikawa S, Kitazono S, Horiike A, Shiba K, Ishizuka T, Nishio M, Matsusaka S*. A novel system to detect circulating tumor cells using two different size-selective microfilters. Anticancer Res.40 (10): 5577-5582, 2020. (IF:1.994) (CI:0)
7. Miyamoto Y, Schirripa M, Suenaga M, Cao S, Zhang W, Okazaki S, Berger MD, Matsusaka S, Yang D, Ning Y, Baba H, Loupakis F, Lonardi S, Pietrantonio F, Borelli B, Cremolini C, Yamaguchi T, Lenz HJ*. A polymorphism in the cachexia-associated gene INHBA predicts efficacy of regorafenib in patients with refractory metastatic colorectal cancer. PloS One. 15(9): e0239439, 2020.
8. Abd El-Sadek I, Miyazawa A, Tzu-Wei Shen L, Makita S, Fukuda S, Yamashita T, Oka Y, Mukherjee P, Matsusaka S, Oshika T, Kano H, Yasuno Y. Optical coherence tomography-based tissue dynamics imaging for longitudinal and drug response evaluation of spheroids. Biomed Opt Express. 11(11): 6231-6248, 2020.

2019年度

1. Suzuki Y, Kobayashi K, ..., Matsusaka S, et al. Label-free chemical imaging flow cytometry by high-speed multicolor stimulated Raman scattering. Proc Natl Acad Sci U S A. 2019: 116:15842-15848.
2. Isozaki A, Mikami H, ..., Matsusaka S, et al. A practical guide to intelligent image-activated cell sorting. Nat Protoc. 2019:14(8):2370-2415.
3. Kondo K, Matsusaka S, et al. Long-term results of a multicenter phase II study of preoperative chemoradiotherapy with S-1 plus oxaliplatin for locally advanced rectal cancer (JACCRO CC-04: SHOGUN Trial). Radiother Oncol. 2019: 134:199-203.
4. Nitta N, Sugimura T, ..., Matsusaka S, et al. Intelligent Image-Activated Cell Sorting. Cell. 2018: 175(1):266-276.
5. Hanna DL, Loupakis F, ..., Matsusaka S, et al. Prognostic Value of ACVRL 1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study. Clin Colorectal Cancer. 2018: 17(3):e471-e488.
6. Suenaga M, Akiyoshi T, ..., Matsusaka S, et al. A Feasibility Study of Capecitabine and Oxaliplatin for Patients with Stage II/III Colon Cancer – ACTOR Study. Anticancer Res. 2018: 38(3): 1741-1747.
7. Berger MD, Stintzing S, ..., Matsusaka S, et al. A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab. Clin Cancer Res. 2018: 24(4) 784-793.
8. Kimura Y, Fujii M, ..., Matsusaka S, et al. Multicenter phase II study of trastuzumab plus S-2 alone in elderly patients with HER2-positive advanced gastric cancer (JACCRO GC-06). Gastroc Cancer. 2018: 21(3): 421-427.
9. Matsusaka S, et al. Prognostic impact of FOXF1 polymorphisms in gastric cancer patients. Pharmacogenomics J. 2018: 18(2): 262-269.

学会発表
2021年度

1. 森倫子、古川安津子、Turan Bilal、益田泰輔、新井史人、松阪諭
   肺がん患者血中CTCにおけるEGFR変異解析を目指した１細胞解析方法の確立
   第７回リキット・バイオプシー研究会　2022年1月28日−29日（WEB）
2. Mori T, El-Sadek Abd, makita S, Mukherjee P, Zhu L. Furukawa A, Yasuno Y, Matsusaka S. Optical-coherence-tomography based tissue dynamics imaging method for tumor spheroid drug response. Pacifichem 2021, Dec 16-21,2021, Virtual

2020年度

1. ゲノム解析を目指したCTC診断装置の開発
   松阪 諭
   第4回Liquid Biopsy研究会 シンポジウム「ゲノム医療の時代におけるリキッドバイオプシーの役割」 2020年

2019年度

1. 招待講演 化学とマイクロ・ナノシステム学会第37回研究会「がん診断・治療におけるCTCの有用性と今後の展望」
2. Anti-Cancer Treatment: Symposium 6 Biomarker 「CTC, and circulating DNA」のChair & Speaker
3. 第22回日本がん分子標的治療学会学術集会: がん分子標的治療の基本講座 セッション１９「CTC」
4. 第22回日本がん分子標的治療学会学術集会: ワークショップ１１　バイオマーカーII リキッドバイオプシーのモデレーター

研究費
科学研究費助成事業
2021年度〜2023年度　基盤研究(B)「サイズ分画化された血液で最大化するがん診断情報」

• 研究代表者：松阪　諭

2021年度〜2023年度　基盤研究(B)「インテリジェント画像活性細胞選択法によるCTC検査法の創出」

• 研究代表者：磯崎　瑛宏
• 研究分担者：松阪　諭

2021年度〜2023年度　基盤研究(B)「ダイナミクスOCT顕微鏡の開発」

• 研究代表者：安野　嘉晃
• 研究分担者：松阪　諭

2019年度〜2022年度　基盤研究(B) 「微小血管循環培養システムの開発とインビトロ癌シミュレーターとしての応用」

• 研究代表者：杉浦　慎治
• 研究分担者：松阪　諭

2019年度　基盤研究(C)　「クラスターCTCに注目した泌尿器癌の分子基盤に基づいたバイオマーカーの開発」

• 研究代表者：松岡　妙子
• 研究分担者：松阪　諭

日本医療研究開発機構　先進的医療機器・システム等技術開発事業
2020年度〜2022年度　基盤技術開発プロジェクト　「全血対応が可能な細胞分取装置による癌モニタリング」

• 研究代表者：益田　泰輔
• 研究分担者：松阪　諭

国立研究開発法人　科学技術振興機構
2021年度〜2026年度 CREST（革新光部門）「計算光学顕微鏡による生きた組織の機能イメージング」

• 研究代表者：安野　嘉晃
• 研究分担者：松阪　諭

2016年度〜2018年度 内閣府革新的研究開発プログラム 「血中CTCの取りこぼしを許さない高精度血液検査技術の開発」

• 研究代表者：松阪　諭

特許

1. (PCT出願。日本出願はPCTにともない擬制取下) 特願PCT/JP2020/004819 (特開WO2020-162595)
   発明者： 加納英明、松阪諭、岩村拓海、沈之為、松本潤一
   発明の名称： 被験物質への感受性の判定方法、被験物質への感受性の判定装置、抗癌剤のスクリーニング方法、抗癌剤の候補物質の製造方法、学習済モデルの製造方法、学習済モデルの製造装置、および選抜方法
   出願人： 国立大学法人筑波大学
   出願日：2020/2/7
   
   
2. 出願番号：2022-3302
   発明者： 松阪諭、久野村駿、平山佑介、宮本貴幸、小山伸也
   発明の名称： 細胞外小胞低減システム
   出願人： 国立大学法人筑波大学、株式会社カネカ、東洋紡株式会社
   出願日：2022/1/12
   
   
3. 出願番号：2022-017529
   発明者： 松阪諭、古川亜津子、森　倫子、絹田精鎮、市野沢義行、小林将士
   発明の名称： 細胞培養容器
   出願人： 国立大学法人筑波大学、株式会社オプトニクス精密
   出願日：2022/2/7