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Environmental Biology Laboratory Faculty of Medicine University of Tsukuba
環境生物学研究室

The 23rd Symposium of the  Japanese Arsenic Society

Environmental Biology Laboratory 
Faculty of Medicine University of Tsukuba
1-1-1 Tennodai, Tsukuba Ibaraki,
305-8575, Japan

Japanese

Achievement

2021

  1. Nakahara K, Hamada K, Tsuchida T, Takasugi N, Abiko Y, Shien K, Toyooka S, Kumagai Y, Uehara T. Covalent N-arylation by the pollutant 1,2-naphthoquinone activates the EGF receptor. Journal of Biological Chemistry 2021 Mar;296:100524. doi: 10.1016/j.jbc.2021.100524
  2. Abiko Y, Kurosawa K, Yamakawa H, Kumagai Y. Activation of PTP1B/EGFR signaling and cytotoxicity during combined exposure to ambient electrophiles in A431 cells. Journal of Toxicological Sciences 2021;46(4):177-185. doi: 10.2131/jts.46.177.
  3. Abiko Y, Katayama Y, Akiyama M, Kumagai Y. Lipophilic compounds in garlic decrease the toxicity of methylmercury by forming sulfur adducts. Food and Chemical Toxicology 2021 Apr;150:112061. doi: 10.1016/j.fct.2021.112061
  4. Seki N, Akiyama M, Yamakawa H, Hase K, Kumagai Y, Yun-Gi Kim. Adverse effects of MeHg on gut bacteria and accelerated accumulation of mercury in the organs due to the disruption of gut microbiota. Journal of Toxicological Sciences 2021;46(2):91-97. doi: 10.2131/jts.46.91
  5. Hiraoka H, Nomura R, Takasugi N, Akai R, Iwawaki T, Kumagai Y, Fujimura M, Uehara T. Spatiotemporal analysis of the unfolded protein response transition induced by methylmercury in the mouse brain. Archives of Toxicology 2021 Apr;95(4):1241-1250. doi: 10.1007/s00204-021-02982-9
  6. Abiko Y, Aoki H, Kumagai Y. Effect of combined exposure to environmental aliphatic electrophiles from plants on Keap1/Nrf2 activation and cytotoxicity in HepG2 cells: a model of an electrophile exposome. Toxicology and Applied Pharmacology 2021 Feb 15;413:115392. doi: 10.1016/j.taap.2020.115392.

2016-2020

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