研究業績
令和3年度（2021年度）
医学医療系業績
1. Kazuya Nagasaki ,Emiko Seo, Tetsuhiro Maeno,Hiroyuki Kobayashi. Diagnostic accuracy of the Single-item Measure of Burnout (Japanese version) for identifying medical resident burnout. Journal of General and Family Medicine. 2022;00:1–7.DOI: 10.1002/jgf2.535
2. Shintaro Akiyama, Taku Sakamoto, Joshua M. Steinberg, Yutaka Saito, Kiichiro Tsuchiya. Evolving roles of magnifying endoscopy and endoscopic resection for neoplasia in inflammatory bowel diseases.World Journal of Gastrointestinal Oncology. 2022; 14(3): 646-653. DOI: 10.4251/wjgo.v14.i3.646
3. Shintaro Akiyama, Jacob E. Ollech, Cindy Traboulsi, Victoria Rai, Laura R. Glick, Yangtian Yi, Joseph Runde, Andrea D. Olivas, Christopher R. Weber, Russell D. Cohen, Kinga B. Skowron Olortegui, Roger D. Hurst, Konstantin Umanskiy, Benjamin D. Shogan, Michele A. Rubin, Sushila R. Dalal, Atsushi Sakuraba, Joel Pekow, Eugene B. Chang, Neil H. Hyman and David T. Rubin. Histopathology of colectomy specimens predicts endoscopic pouch phenotype in patients with ulcerative colitis.Digestive Diseases and Sciences. 2022 in press DOI: 10.1007/s10620-022-07405-y
4. Shintaro Akiyama, Nathaniel A. Cohen, Joshua M. Steinberg, Scott Friedberg, Russell D. Cohen.Rare and Well Done: Endoscopic Control of Colonic Hemorrhage in Severe Ulcerative Colitis. Digestive Diseases and Sciences. 2022 Mar;67(3):805-809. DOI: 10.1007/s10620-022-07446-3
5. Shintaro Akiyama, Jacob E. Ollech, Victoria Rai, Laura R. Glick, Yangtian Yi, Cindy Traboulsi, Joseph Runde, Russell D. Cohen, Kinga B. Skowron, Roger D. Hurst, Konstantin Umanskiy, Benjamin D. Shogan, Neil H. Hyman, Michele A. Rubin, Sushila R. Dalal, Atsushi Sakuraba, Joel Pekow, Eugene B. Chang, and David T. Rubin. Endoscopic phenotype of the J pouch in patients with inflammatory bowel disease: A new classification for pouch outcomes. Clinical Gastroenterology and Hepatology. 2022 Feb;20(2):293-302.e9.
6. Nakamura Y, Okamoto W, Denda T, Nishina T, Komatsu Y, Yuki S, Yasui H, Esaki T, Sunakawa Y, Ueno M, Shinozaki E, Matsuhashi N, Ohta T, Kato K, Ohtsubo K, Bando H, Hara H, Satoh T, Yamazaki K, Yamamoto Y, Okano N, Terazawa T, Kato T, Oki E, Tsuji A, Horita Y, Hamamoto Y, Kawazoe A, Nakajima H, Nomura S, Mitani R, Yuasa M, Akagi K, Yoshino T. Clinical Validity of Plasma-Based Genotyping for Microsatellite Instability Assessment in Advanced GI Cancers: SCRUM-Japan GOZILA Substudy. JCO Precis Oncol. 2022 Feb;6:e2100383.
7. Atsushi Taninakaab, Shunta Ugajina, Hiromi Kurokawac, Yu Nagoshia, Mayuka Kamiyanagia, Osamu Takeuchia, Hirofumi Matsui and Hidemi Shigekawa. Direct analysis of the actin-filament formation effect in photodynamic therapy.Royal Society of Chemistry.2022 Feb 16;12(10):5878-5889.doi: 10.1039/d1ra09291j.
8. Hiromi Kurokawa, Atsushi Taninaka, Toru Yoshitomi, Hidemi Shigekawa and Hirofumi Matsui. Near-Infrared Light Irradiation of Porphyrin-Modified Gold Nanoparticles Promotes Cancer-Cell-Specific Cytotoxicity. Molecules.2022 Feb 12;27(4):1238.doi: 10.3390/molecules27041238.
9. Hayashi Y, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Miyake A, Fujishiro M, Masamune A, Takehara T. The degree of mucosal atrophy is associated with post-endoscopic submucosal dissection bleeding in early gastric cancer. J Gastroenterol Hepatol. 2022 Feb 7. doi: 10.1111/jgh.15793. Online ahead of print.
10. Hagiwara Y, Yamamoto Y, Inagaki Y, Tomisaki R, Tsuji M, Fukuda S, Fukuda S, Onoda T, Suzuki H, Niisato Y, Tange Y, Ikeda N, Yamada K, Kobayashi M, Akutsu D, Yamada T, Moriwaki T, Narasaka T, Suzuki H, Tsuchiya K. Severe Gastrointestinal Disorder due to Capecitabine Associated with Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Literature Review. Intern Med. 2022 Feb 1. doi: 10.2169/internalmedicine.8636-21. Epub ahead of print.
11. Zhenyao H, Kurokawa H, Matsui H, Chunlin H, Kaituo W, Yuezou W, Gjergj D, Otsuki A, Fujita T. Stability and Free Radical Production for CO2 and H2 in Air Nanobubbles in Ethanol Aqueous Solution. Nanomaterials 2022, 12(2),237
12. Nakajima T, Sakamoto T, Hori S, Yamada S, Ikematsu H, Harada K, Chiu HM, Kiriyama S, Michida T, Hotta K, Sakamoto N, Abe T, Chino A, Fukuzawa M, Kobayashi N, Fukase K, Matsuda T, Murakami Y, Ishikawa H, Saito Y. Optimal surveillance interval after piecemeal endoscopic mucosal resection for large colorectal neoplasia: a multicenter randomized controlled trial. Surg Endosc. 2022 Jan;36(1):515-525.
13. Kishino T, Nagata N, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kawagishi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Kaise M. Endoscopic direct clipping versus indirect clipping for colonic diverticular bleeding: A large multicenter cohort study. United European Gastroenterol J. 2022 Jan 12. doi: 10.1002/ueg2.12197.
14. Nakasya A, Hagiwara Y, Ikoma T, Kurioka Y, Matsumoto T, Yamamoto Y, Tsuduki T, Kajiwara T, Moriwaki T, Nishina T, Yamashita N, Hyodo I. Nanoparticle albumin-bound paclitaxel and ramucirumab versus paclitaxel and ramucirumab as second-line chemotherapy for unresectable advanced or recurrent gastric cancer: a multicenter, propensity score-matched analysis (CROSS SELL study). Int J Clin Oncol. 2022 Jan 28. doi: 10.1007/s10147-022-02114-y. Online ahead of print.
15. Ikezawa, K, Hirose, M, Maruyama, T, et al. Effect of early nutritional initiation on post-cerebral infarction discharge destination: A propensity-matched analysis using machine learning. Nutrition & Dietetics. 2022; 79( 2): 247- 254.
16. Kobayashi K, Nagata N, Furumoto Y et al. Effectiveness and adverse events of endoscopic clipping versus band ligation for colonic diverticular hemorrhage: a large-scale multicenter cohort study. Endoscopy 2021 (efirst).
17. Hashimoto M, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Doyama H, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Fujishiro M, Masamune A, Ohira H; Collaborators. Rebleeding in patients with delayed bleeding after endoscopic submucosal dissection for early gastric cancer. Dig Endosc. 2021 Nov;33(7):1120-1130.doi: 10.1111/den.13943.
18. Tange Y, Hasegawa N, Sugiyama Y, Endo M, Terasaki M, Yamamoto Y, Ishige K, Fukuda K, Suzuki H, Mizokami Y. Usefulness of argon plasma coagulation for bleeding around hepaticojejunal anastomosis. DEN open. 2021 Nov 2;2(1):e69.
19. Shintaro Akiyama, Austin Lin, Cindy Traboulsi, David T. Rubin. Treatment of Crohn’s disease and concomitant alopecia areata with tofacitinib. ACG Case Reports Journal 2021; in press.
20. Shintaro Akiyama, Akihiro Yamada, Atsushi Sakuraba. Chapter 41: How does perioperative immune suppression affect surgical outcomes in inflammatory bowel disease? Curbside Consultation in Inflammatory Bowel Disease: 49 Clinical Questions, Third Edition; 2021 in press
21. Joseph Runde, Amarachi Erondu, Shintaro Akiyama, Cindy Traboulsi, Victoria Rai, Laura R. Glick, Yangtian Yi, Jacob E. Ollech, Russell D. Cohen, Kinga B. Skowron, Roger D. Hurst, Konstatin Umanskiy, Benjamin D. Shogan, Neil H. Hyman, Michele A. Rubin, Sushila R. Dalal, Atsushi Sakuraba, Joel Pekow, Eugene B. Chang, and David T. Rubin. Outcomes of Ileoanal Pouch Anastomosis in Pediatric Ulcerative Colitis Are Worse in the Modern Era: A Time Trend Analysis. Inflammatory Bowel Diseases 2021; in press
22. Hoshiai S, Irie T, Mori K, Hasegawa N, Fukuda K, Ishige K, Mori K, Arai H, Takahashi N, Nakajima T. A Transarterial Chemoembolization of Balloon-23.Occluded Alternate Infusions of Cisplatin and Gelatin Particles for Hepatocellular Carcinoma: A Phase I/II Multicenter Prospective Study of Safety and Efficacy. Journal of Vascular and Interventional Radiology 2021 (in press)
23. Second-line chemotherapy after early disease progression during first-line chemotherapy containing bevacizumab for patients with metastatic colorectal cancer. Yamamoto S, Nagashima K, Kawakami T, Mitani S, Komoda M, Tsuji Y, Izawa N, Kawakami K, Yamamoto Y, Makiyama A, Yamazaki K, Masuishi T, Esaki T, Nakajima TE, Okuda H, Moriwaki T, Boku N. BMC Cancer. 2021 Oct 29;21(1):1159.
24. Hirose S, Hasegawa N, Mori K, Endo M, Terasaki M, Ishige K, Fukuda K, Mizokami Y, Tsuchiya K. Percutaneous transhepatic obliteration related procedures for isolated gastric varices: experience of three cases. Clinical Journal of Gastroenterology 2021 Oct 26;S1051-0443(21)01440-8.
25. Okada K, Watahiki T, Horie K, Takayama T, Aida Y, To K, Shida T, Ishige K, Nishiyama H, Shoda J, Suzuki H. The prevalence and clinical implications of pancreatic fat accumulation identified during a medical check-up. Medicine. 2021 Oct 15;100(41):e27487.
26. Mukherjee P, Miyazawa A, Fukuda S, Yamashita T, Lukmanto D, Okada K, El-Sadek IA, Zhu L, Makita S, Oshika T, Yasuno Y. Label-free multi-contrast imaging of ex vivo liver microvasculature in mice by Jones matrix optical coherence tomography. Sci Rep. 2021 Oct 8;11:20054.
27. Numajiri H, Mizumoto M, Okumura T, Fukumitsu N, Hasegawa N, Ishige K, Fukuda K, Ishizu T, Tokushige K, Sakurai H, Proton Beam Therapy for Hepatocellular Carcinoma after the Fontan Procedure. Journal of Cancer Therapy, 2021 Oct, 12, 554-562
28. Shintaro Akiyama, Akihiro Yamada, Jacob E. Ollech, Yuga Komaki, Fukiko Komaki, Joel Pekow, Sushila R. Dalal, Russell D. Cohen, David T. Rubin, Atsushi Sakuraba. Predictability of Simple Endoscopic Score for Crohn’s disease for postoperative outcomes in Crohn’s disease. Journal of Gastroenterology and Hepatology 2021 Oct; 36(10): 2785-2793.
29. Minashi K, Yamada T, Hosaka H, Amagai K, Shimizu Y, Kiyozaki H, Sato M, Soeda A, Endo S, Ishida H, Kamoshida T, Sakai Y, Shitara K. Cancer-related FGFR2 overexpression and gene amplification in Japanese patients with gastric cancer. JJCO 2021 Oct 5 ;51(10) :1523-33.
30. K.Ando, M.Fujiya, K.Watanabe, S.Hiraoka, Y.Kakuta, S.Tanaka, H.Iijima, T.Mizushima, T.Kobayashi, M.Nagahori, H.Ikeuchi, S.Kato, T.Torisu, K.Kobayashi, R.Hokari, T.Fukui, T.Kagaya, M.Esaki, S.Yanai, D.Abukawa, M.Naganuma, S.Motoya, M.Saruta, S.Bamba, Y.Ohkita, M.Sasaki, K.Uchiyama, K.Fukuda, H.Suzuki, H.Nakase, T.Shimizu, M.Iizuka, M.Watanabe, Y.Suzuki, T.Hisamatsu. A nationwide survey concerning the mortality and risk of progressing severity due to arterial and venous thromboembolism in inflammatory bowel disease in Japan J Gastroenterol. 2021 Oct 5. Online ahead of print.
31. Ogawa K, Ishikawa H, Hisakura K, Hiroshima Y, Moriwaki T, Yamada T, Yamamoto Y, Akashi Y, Owada Y, Ohara Y, Enomoto T, Furuya K, Doi M, Shimomura O, Takahashi K, Hashimoto S, Sakurai H, Oda T. Retrospective analysis of neoadjuvant chemotherapy followed by surgery versus definitive chemoradiotherapy with proton beam for locally advanced esophageal squamous cell carcinoma. Int J Clin Oncol. 2021 Oct;26(10):1856-1863.
32. Kasuga K, Yamada M, Shida D, Tagawa T, Takamaru H, Sekiguchi M, Sakamoto T, Uraoka T, Sekine S, Kanemitsu Y, Saito Y. Treatment outcomes of endoscopic submucosal dissection and surgery for colorectal neoplasms in patients with ulcerative colitis. United European Gastroenterol J. 2021 Oct;9(8):964-972.
33. Shiroma S, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Fujishiro M, Masamune A, Fujisaki J. Timing of bleeding and thromboembolism associated with endoscopic submucosal dissection for gastric cancer in Japan. J Gastroenterol Hepatol. 2021 Oct;36(10):2769-2777. Epub 2021 May 26.
34. Nakamura Y, Ishitsuka Y, Sasaki K, Ishizuki S, Tanaka R, Okiyama N. Furuta J, Yamada T, Fujisawa Y. A prospective, phase II study on the safety and efficacy of negative pressure closure for the stabilization of split-thickness skin graft in large or muscle-exposing defects: the NPSG study. Journal of Dermatology 2021 Sep ;48(90) :1350-1356.
35. Muro K, Kojima T, Moriwaki T, Kato K, Nagashima F, Kawakami H, Ishihara R, Ogata T, Satoh T, Iwakami K, Han S, Yatsuzuka N, Takami T, Bhagia P, Doi T. Second-line pembrolizumab versus chemotherapy in Japanese patients with advanced esophageal cancer: subgroup analysis from KEYNOTE-181. Esophagus. 2021 Sep 30. Online ahead of print.
36. Hiromi Kurokawa and Hirofumi Matsui. The Cytotoxicity of Doxorubicin Can Be Accelerated by a Combination of Hyperthermia and 5-Aminolevulinic Acid. Antioxidants 2021 Sep 27, 10(10), 1531
37. Watanabe S, Nishimura R, Shirasaki T, Katsukura N, Hibiya S, Kirimura S, Negi M, Okamoto R, Matsumoto Y, Nakamura T, Watanabe M, Tsuchiya K*. Schlafen 11 is a novel target for mucosal regeneration in Ulcerative Colitis. J Crohns Colitis. 15(9):1558-1572, 2021 Sep 25 (* correspondence)
38. H Kurokawa, A Taninaka, H Shigekawa, H Matsui. Dabigatran Etexilate Induces Cytotoxicity in Rat Gastric Epithelial Cell Line via Mitochondrial Reactive Oxygen Species Production. Cells 2021, Sep 22 10(10), 2508 - Cells, 2021 - mdpi.com
39. M.Fujita, H.Suzuki, F.Fukai. Involvement of integrin-activating peptides derived from tenascin-C in colon cancer progression. World J Gastrointest Oncol. 2021 Sep 15;13(9):980-994.
40. Pia Loreto Werlinger Bravo, Hui Jin, Hyunwoo Park, Min Sang Kim, Hirofumi Matsui, Hanki Lee and Joo-Won Suh. Antithrombotic Effect of the Ethanol Extract of Angelica gigas Nakai (AGE 232). Life Volume11,2021 Sep 9 Isseu9- mdpi.com
41. Yabuuchi Y, Hatta W, Tsuji Y, Yoshio T, Kakushima N, Hoteya S, Doyama H, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Fujishiro M, Masamune A, Ono H. Influence of hospital volume on bleeding after endoscopic submucosal dissection for early gastric cancer in Japan: a multicenter propensity score-matched analysis. Surg Endosc. 2021 Sep 7. Epub ahead of print.
42. Shintaro Akiyama, Tina G Rodriguez, David T Rubin. Stratifying Risks of Ileal Pouch Outcomes. Clin Gastroenterol Hepatol 2021 Sep 3;S1542-3565(21)00931-9.
43. Suguru Hirose, Chiaki Enami, Natsumi Kawamatsu, Yoshimi Ito, Tsubasa Onoda, Yutaro Sugiyama, Hirosumi Suzuki, Miho Nagafuchi, Takafumi Ikeda, Yusuke Niisato, Takeshi Yamada, Yoshiyuki Yamamoto, Toshikazu Moriwaki, Hideo Suzuki. Systemic chemotherapy combined with anti-epidermal growth factor receptor antibody therapy for RAS wild-type appendiceal signet-ring cell carcinoma: a series of three cases. Int Canc Conf J. 2021 Aug 29.
44. Yabe Y, Kim T, Oh S, Shida T, Oshida N, Hasegawa N, Okada K, Someya N, Mizokami Y, Shoda J. Relationships of dietary habits and physical activity status with non-alcoholic fatty liver disease featuring advanced fibrosis. Int J Environ Res Public Health. 2021 Aug 25;18:8918.
45. Sakamoto T, Nakashima H, Nakamura K, Nagahama R, Saito Y. Performance of Computer-Aided Detection and Diagnosis of Colorectal Polyps Compares to That of Experienced Endoscopists. Dig Dis Sci. 2021 Aug 17. Epub ahead of print.
46. Nagata N, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Kishino T, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kawagishi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Fukuzawa M, Itoi T, Uemura N, Kawai T, Kaise M. Identifying Bleeding Etiologies by Endoscopy Affected Outcomes in 10,342 Cases With Hematochezia: CODE BLUE-J Study. Am J Gastroenterol. 2021 Aug 13. Epub ahead of print.
47. Kamba S, Tamai N, Saitoh I, Matsui H, Horiuchi H, Kobayashi M, Sakamoto T, Ego M, Fukuda A, Tonouchi A, Shimahara Y, Nishikawa M, Nishino H, Saito Y, Sumiyama K. Reducing adenoma miss rate of colonoscopy assisted by artificial intelligence: a multicenter randomized controlled trial. J Gastroenterol. 2021 Aug;56(8):746-757.
48. Yokota T, Saito Y, Takamaru H, Sekine S, Nakajima T, Yamada M, Sakamoto T, Taniguchi H, Kushima R, Tsukamoto S, Shida D, Kanemitsu Y, Matsuda T. Spontaneous Regression of Mismatch Repair-Deficient Colon Cancer: A Case Series. Clin Gastroenterol Hepatol. 2021 Aug;19(8):1720-1722.e3.
49. Asakawa T, Onizawa M, Saito C, Hikichi R, Yamada D, Minamidate A, Mochimaru T, Asahara SI, Kido Y, Oshima S, Nagaishi T, Tsuchiya K, Ohira H, Okamoto R, Watanabe M. Oral administration of D-serine prevents the onset and progression of colitis in mice. J Gastroenterol. 56(8):732-745, 2021 Aug
50. Moriwaki T, Gosho M, Sugaya A, Yamada T, Yamamoto Y, Hyodo I. Optimal Maintenance Strategy for First-Line Oxaliplatin-Containing Therapy with or without Bevacizumab in Patients with Metastatic Colorectal Cancer: A Meta-Analysis. Cancer Res Treat. 2021 Jul;53(3):703-713.
51. Wang X, Yamamoto Y, Imanishi M, Zhang X, Sato M, Sugaya A, Hirose M, Endo S, Natori Y, Moriwaki T, Yamato K, Hyodo I. Enhanced G1 arrest and apoptosis via MDM4/MDM2 double knockdown and MEK inhibition in wild-type TP53 colon and gastric cancer cells with aberrant KRAS signaling. Oncol Lett. 2021 Jul;22(1):558.
52. Sakamoto T, Cho H, Saito Y. Clinical Applications of Linked Color Imaging and Blue Laser/Light Imaging in the Screening, Diagnosis, and Treatment of Superficial Colorectal Tumors. Clin Endosc. 2021 Jul;54(4):488-493.
53. Maehara K, Hijioka S, Sakamoto T, Maruki Y, Tamada K, Okusaka T, Saito Y. Novel biliary drainage of a choledochojejunal anastomotic stenosis using a double-balloon endoscope and forward-viewing endoscopic ultrasound. Endoscopy. 2021 Jul;53(7):E242-E244.
54. Nagata N, Niikura R, Ishii N, Kaise M, Omata F, Tominaga N, Kitagawa T, Ikeya T, Kobayashi K, Furumoto Y, Narasaka T, Iwata E, Sugimoto M, Itoi T, Uemura N, Kawai T. Cumulative evidence for reducing recurrence of colonic diverticular bleeding using endoscopic clipping versus band ligation: Systematic review and meta-analysis. J Gastroenterol Hepatol. 2021 Jul;36(7):1738-1743.
55. Akashi Y, Ogawa K, Narasaka T, Enomoto T, Hisakura K, Ohara Y, Owada Y, Furuya K, Shimomura O, Takahashi K, Hashimoto S, Oda T. A scoring system to predict surgical difficulty in minimally invasive surgery for gastric submucosal tumors. Am J Surg. 2021 Jul 21:S0002-9610(21)00408-6.
56. Minamidate A, Onizawa M, Saito C, Hikichi R, Mochimaru T, Murakami M, Sakuma C, Asakawa T, Hiraoka Y, Oshima S, Nagaishi T, Tsuchiya K, Ohira H, Okamoto R, Watanabe M. A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production. Biochem Biophys Rep. 27:101065 eCollection 2021 Jul 8
57. H Kurokawa, H Ito, H Matsui. Porphylipoprotein Accumulation and Porphylipoprotein Photodynamic Therapy Effects Involving Cancer Cell-Specific Cytotoxicity. International Journal of Molecular Sciences Volume22,2021 Jul 7 Issue14- mdpi.com
58. Watanabe S, Hibiya S, Katsukura N, Kitagawa S, Sato A, Okamoto R, Watanabe M, Tsuchiya K*. Importance of telomere shortening in the pathogenesis of ulcerative colitis: A new treatment from the aspect of telomeres in intestinal epithelial cells. J Crohns Colitis. 2021 Jun 28 Online ahead of print. (* correspondence)
59. M Oshimo, F Nakashima, K Kai, H Matsui, T Shibata, & M Akagawa. Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress. Free radical Research Volume 55, 2021 Jun 21-Isseu6-Taylor & Francis
60. Kasuga K, Saito Y, Takamaru H, Yamada M, Sakamoto T, Sekine S, Uraoka T. Optical real-time biopsy by endocytoscopy: a case of sessile serrated lesion with dysplasia. Endoscopy. 2021 Jun 18. Epub ahead of print.
61. Sekiguchi M, Igarashi A, Mizuguchi Y, Takamaru H, Yamada M, Sakamoto T, Maltzman H, Falkén Y, Esaki M, Matsuda T, Saito Y. Cost-effectiveness analysis of endoscopic resection for colorectal laterally spreading tumors: Endoscopic submucosal dissection versus piecemeal endoscopic mucosal resection. Dig Endosc. 2021 Jun 8. ahead of print.
62. Nakajima H, Fukuoka S, Masuishi T, Takashima A, Kumekawa Y, Kajiwara T, Yamazaki K, Negoro Y, Komoda M, Makiyama A, Denda T, Hatachi Y, Suto T, Sugimoto N, Enomoto M, Ishikawa T, Kashiwada T, Ando K, Yuki S, Okuyama H, Kusaba H, Sakai D, Okamoto K, Tamura T, Yamashita K, Gosho M, Moriwaki T. Clinical Impact of Primary Tumor Location in Metastatic Colorectal Cancer Patients Under Later-Line Regorafenib or Trifluridine/Tipiracil Treatment. Front Oncol. 2021 Jun 15;11:688709. eCollection 2021.
63. Shintaro Akiyama, Atsushi Sakuraba. Distinct roles of interleukin-17 and T helper 17 cells among autoimmune diseases. Journal of Translational Autoimmunity 2021 May; 4: 100104.
64. Shintaro Akiyama, Thomas G. Cotter, Atsushi Sakuraba. Risk of hepatitis B virus reactivation in patients with autoimmune diseases undergoing non-tumor necrosis factor-targeted biologics. World Journal of Gastroenterology 2021 May; 27(19): 2312-2324.
65. Inoki K, Abe S, Tanaka Y, Yamamoto K, Hihara D, Ichijima R, Nakatani Y, Chen HY, Takamaru H, Sekiguchi M, Yamada M, Sakamoto T, Nonaka S, Suzuki H, Yoshinaga S, Oda I, Matsuda T, Saito Y. Reduced Intravenous Fluorescein Dose for Upper and Lower Gastrointestinal Tract Probe-Based Confocal Laser Endomicroscopy. Clin Endosc. 2021 May;54(3):363-370.
66. Okagawa Y, Abe S, Takamaru H, Sekiguchi M, Yamada M, Sakamoto T, Saito Y. A novel technique for adjusting traction direction during colorectal endoscopic submucosal dissection using S-O clip. Endoscopy. 2021 May;53(5):E177-E178.
67. Watanabe S, Hibiya S, Katsukura N, Kitagawa S, Sato A, Okamoto R, Watanabe M, Tsuchiya K*. Influence of chronic inflammation on the malignant phenotypes and the plasticity of colorectal cancer cells. Biochem Biophys Rep. 26:101031. eCollection 2021 May. (* correspondence)
68. Miura I, Komine S, Okada K (co-first author), Wada S, Warabi E, Uchida F, Oh S, Suzuki H, Mizokami Y, Shoda J. Prevention on non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice. Physiol Rep. 2021 May;9:e14859.
69. Nakamura K, Marushima A, Takahashi Y, Kimura A, Asami M, Egawa S, Kaneko J, Kondo Y, Yonekawa C, Hoshiyama E, Yamada T, Maruo K, Inoue Y, IENE ECT with LIFE study group. Levetiracetam versus fosphenytoin as second line treatment after diazepam for status epilepticus: study protocol for a multicenter non-inferiority designed randomized control trial. Trials. 2021 May 2 ;22(1) :317.
70. Kiyotoki S, Nishikawa J, Nagata N, Niikura R, Doyama H, Imagawa A, Hasatani K, Hatta W, Sumiyoshi T, Nebiki H, Nagami Y, Nishida T, Kakushima N, Iguchi M, Tomida H, Inoue T, Kuribayashi S, Narasaka T, Hikichi T, Yada T, Ochiai Y, Furuhashi H, Yoshio T, Mori H, Yamauchi K, Kitamura K, Fujita T, Mabe K, Mikami T, Goto A, Akashi M, Hamamoto Y, Fujishiro M, Sakaida I. Exploration of the characteristics of chronotypes in upper gastrointestinal tract diseases: a multicenter study in Japan. Chronobiol Int. 2021 Apr;38(4):534-542.
71. Niisato Y, Moriwaki T, Fukuoka S, Masuishi T, Takashima A, Kumekawa Y, Kajiwara T, Yamazaki K, Esaki T, Makiyama A, Denda T, Hatachi Y, Suto T, Sugimoto N, Shimada Y. Clinical Outcomes Following Trifluridine/Tipiracil Treatment for Patients With Metastatic Colorectal Cancer Ineligible for Regorafenib Treatment. Anticancer Res. 2021 Apr;41(4):2203-2207.
72. Hiromi Kurokawa, Atsushi Taninaka, Hidemi Shigekawa, Hirofumi Matsui The cytotoxicity of cyclophosphamide is enhanced in combination with monascus pigment. Journal of Clinical Biochemistry and Nutrition 2021 Apr 7 - jstage.jst.go.jp
73. Takamaru H, Saito Y, Sekiguchi M, Yamada M, Sakamoto T, Matsuda T, Sekine S, Ochiai H, Tsukamoto S, Shida D, Kanemitsu Y. Endoscopic Resection Before Surgery Does Not Affect the Recurrence Rate in Patients With High-Risk T1 Colorectal Cancer. Clin Transl Gastroenterol. 2021 Apr 12;12(4):e00336.
74. Mizuguchi Y, Tanaka Y, Cho H, Sekiguchi M, Takamaru H, Yamada M, Sakamoto T, Matsuda T, Hashimoto T, Sekine S, Saito Y. Endoscopic features of isolated and traditional serrated adenoma-associated superficially serrated adenomas of the colorectum. Dig Endosc. 2021 Apr 19. Epub ahead of print.
75. Yatsuda Y, Hirose S, Ito Y, Onoda T, Sugiyama Y, Nagafuchi M, Suzuki H, Niisato Y, Tange Y, Ikeda T, Yamada T, Yamamoto Y, Ohyama Osawa M, Sakamoto N, Moriwaki T, Mizokami Y. A Durable Response after the Discontinuation of Nivolumab in an Advanced Gastric Cancer Patient. Intern Med. 2021 Apr 1;60(7):1011-1017.
76. 坂本琢, 金光幸秀, 斎藤豊. 早期大腸癌に対する内視鏡切除の適応と限界. カレントテラピー. 2021; 39(10): 916-920.
77. 坂本琢, 中村佳子, 斎藤豊. 大腸内視鏡診断支援機能 "CAD EYE" - そのスペックと使いこなすコツ - 消化器内視鏡 2021 8月; 33(8): 1ak347-1352.
78. 斎藤豊, 高丸博之, 柳澤文人, 水口康彦, 谷本泉, 牧口茉衣, 関口正宇, 山田真善, 坂本琢, 松田尚久, 関根茂樹. 大腸拡大内視鏡専用機 - オリンパス社内視鏡 - の使用経験. 消化器内視鏡 2021 8月; 33(8): 1310-1316.
79. 阿部清一郎, 高丸博之, 山田真善, 野中哲, 坂本琢, 鈴木晴久, 吉永繁高, 小田一郎, 松田尚久, 斎藤豊. TXI (Texture and Color Enhancement Imaging) - その原理と臨床応用 - 消化器内視鏡 2021 8月; 33(8): 1227-1231.
80. 小林 真理子, 池澤 和人, 岩井 健太郎, 越智 大介, 大塚 公一朗, 添田 敦子, 杉山 弘明. 皮膚所見をともなわず診断に苦慮した多発無菌性皮下膿瘍合併潰瘍性大腸炎の1例. 日本消化器病学会雑誌. 2021 Jul;118(7):671-678.
81. 黒川宏美、松井裕史：ミトコンドリア由来活性酸素と光線力学療法、光アライアンス、1-4, No6, Vol32, Jun,2021
82. 室伏 景子, 村上 祐司, 牧島 弘和, 森脇 俊和, 佐々木 剛志, 中村 匡希, 福光 延吉, 全田 貞幹, 唐澤 久美子．プレフレイル高齢大腸がん患者のための臨床的提言」放射線治療に関する提言 Part I：Clinical Question 1～5．日本大腸肛門病学会雑誌．2021 年 6月74 巻 7 号 p. 413-421．
83. 室伏 景子, 村上 祐司, 牧島 弘和, 森脇 俊和, 佐々木 剛志, 中村 匡希, 福光 延吉, 全田 貞幹, 唐澤 久美子．プレフレイル高齢大腸がん患者のための臨床的提言」放射線治療に関する提言 Part II：Clinical Question 6～10．日本大腸肛門病学会雑誌．2021 年6月 74 巻 7 号 p. 422-429
84. 坂本琢, 松田尚久, 斎藤豊. 拡大NBI/BLI & pit pattern - どう診断? - 消化器内視鏡 2021 2月; 33(2): 409-411
85. 松田尚久, 関口正宇, 坂本琢. 5mm以下の大腸ポリープ, 見落としちゃダメなの? 消化器内視鏡 2021 1月; 33(1): 406-408.
86. 山崎嵩之, 関口正宇, 高丸博之, 山田真善, 坂本琢, 松田尚久, 関根茂樹, 齋藤豊. 直腸NETの内視鏡切除法, 根治度判定とサーベイランス法. 消化器内視鏡 2021 1月; 33(1): 117-125.
