Higashibata T, Hamano J, Kessoku T, Kajiura S, Hirakawa M, Horie Y, Shimizu M, Oyamada S, Ariyoshi K, Kihara K, Yamanaka Y, Konishi K, Doki K, Takashima Y, Horiuchi M, Homma M, Yamada T, Yamamoto Y, Moriwaki T, Morita T, Nakajima A, Nagaoka H. Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol.
Contemp Clin Trials Commun. 2022 Aug 5;29:100967.
DOI: 10.1016/j.conctc.2022.100967.

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