3 Feb 2021

DHODH inhibition synergizes with DNA-demethylating agents in the treatment of myelodysplastic syndromes

Key Points

• DHODH inhibition synergizes with DNA-demethylating agents in the treatment of MDS.
• DHODH inhibition enhances the incorporation of decitabine into DNA in MDS cells.


Blood Advances - Issue: Blood Adv(2021) 5 (2): 438–450
    https://doi.org/10.1182/bloodadvances.2020001461