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セミナーのお知らせ

開催予定のセミナー情報

特別講演会 Seminar
This seminar will be held in English.
演者/Speaker 中国科学院上海研究所 教授 Lijian Hui
演題/Title Cell identity conversion in regeneration and tumorigenesis
細胞識別の運命転換と腫瘍発生
日時/Date 8月21日(月)18:00~19:00
August 21, 2017 18:00-19:00
場所/Venue イノベーション棟8階講堂
8F Hall, Health & Med Sci. Innovation
講演内容/summary

肝障害・再生と癌化過程、細胞識別と転換及び転分化(ダイレクトリプログラミング)、肝細胞癌発生機構と制御、重度免疫不全FRGラットの開発

Ectopic forced activation of lineage specific transcription factors has been well demonstrated to trigger cell identity conversion in vitro.
Recent studies have shown that, under pathological injury conditions, cell identity conversion is important for tissue regeneration. Liver is an organ with remarkable regeneration capability after injury. Using hepatocyte lineage tracing, it was demonstrated that hepatocytes are identified by reprogramming into progenitor-like cells and contribute to liver regeneration. However, the underlying mechanisms are largely unclear. Here we analyzed how hepatic cell identity conversion was orchestrated in liver regeneration and tumorigenesis.

連絡先 消化器外科 鄭允文(内線3247)
116th WPI-IIIS seminar
This seminar will be held in English.
Date Wednesday, August 23, 2017
Time 12:00-13:00
Venue 1F Auditorium, IIIS Building, University of Tsukuba
Speaker Dr. Hiroaki Wake
Kobe University Graduate School of Medicine
Subject Activity dependent myelin regulation in information processing
Summary Myelination increases conduction velocity and promotes brain functions. Myelin dysregulation is frequently associated with learning and cognition deficits, ultimately causing psychiatric disorders.
Although we have been identified the underlying molecular mechanisms of activity-dependent myelination, the nature of the neural activity changes and the behavior output caused by myelin dysregulation remains unknown. In this research, we visualized neural activity in the motor cortex during motor learning using in vivo two photon microscope to understand the abnormality of neural activity associated with impaired behavior output with myelin dysregulation. We further demonstrate the optogenetic stimulation to compensate the abnormal activity of neural activity to rescue the learning disability.
Contact International Institute for Integrative Sleep Medicine
Phone 029-853-8080 (ext.8080)
第116回WPI-IIISセミナー
日 時 平成29年8月23日(水)12:00-13:00
場 所 筑波大学 医学系エリア 睡眠医科学研究棟 1F 講堂
演 者 Dr. Hiroaki Wake(和氣 弘明 先生)
Kobe University Graduate School of Medicine (神戸大学 大学院医学研究科)
演 題 Activity dependent myelin regulation in information processing
要 旨 Myelination increases conduction velocity and promotes brain functions. Myelin dysregulation is frequently associated with learning and cognition deficits, ultimately causing psychiatric disorders.
Although we have been identified the underlying molecular mechanisms of activity-dependent myelination, the nature of the neural activity changes and the behavior output caused by myelin dysregulation remains unknown. In this research, we visualized neural activity in the motor cortex during motor learning using in vivo two photon microscope to understand the abnormality of neural activity associated with impaired behavior output with myelin dysregulation. We further demonstrate the optogenetic stimulation to compensate the abnormal activity of neural activity to rescue the learning disability.
問い合わせ 国際統合睡眠医科学研究機構(内線8080)
平成29年度科研費セミナー
開催日 平成29年9月6日(水) 18:00~19:40
開催場所 医科学イノベーション棟 8階 講堂
講師及び講演時間

18:05-18:35
正田純一教授 科研費獲得に向けた私のアプローチ

18:35-19:05
船越祐司助教 科研費獲得に向けて~申請書作成で意識すること~

19:05-19:35
橋口晶子 医学 URA「科研費審査システム改革2018」に伴う変更点について

主催 医学医療系学術委員会