Publication 2012
  1. Fujita A, Yoh K, Shimohata H, Morito N, Ojima M, Okamura M, Takahashi S, Yamagata K. A novel diabetes mellitus mouse model, MafA-deficient and beta cell-specific MafK-overexpressing hybrid transgenic mice, developed severe diabetic nephropathy and improved with TCV-116 (candesartan cilexetil) treatment. Exp Animal. 61, 49-57, 2012.

  2. Kondo Y, Iizuka M, Wakamatsu E, Yao Z, Tahara M, Tsuboi H, Sugihara M, Hayashi T, Yoh K, Takahashi S, Matsumoto I, Sumida T. Overexpression of T-bet gene regulates murine autoimmune arthritis. Arthritis Rheum. 64, 62-72, 2012.

  3. Nagamine S, Tamba M, Ishimine H, Araki K, Shiomi K, Okada T, Ohto T, Kunita S, Takahashi S, Wismans RG, van Kuppevelt TH, Masu M, Keino-Masu K. Organ-Specific Sulfation Patterns of Heparan Sulfate Generated by Extracellular Sulfatases Sulf1 and Sulf2 in Mice. J Biol Chem. 287, 9579-9590, 2012.

  4. Sekiguchi Y, Owada J, Oishi H, Katsumata T, Ikeda R, Kudo T, Takahashi S. Non-invasive monitoring of b-cell mass and fetal b-cell genesis in mouse using bioluminescence imaging. Exp Animal. 61, 445-451, 2012.

  5. Tojo M, Takebe A, Takahashi S, Tanaka K, Imamura T, Miyazono K, Chiba T. Smad7-deficient mice show growth retardation with reduced viability. J Biochem. 151, 621-631, 2012.

  6. Matsumoto K, Azami T, Otsu A, Takase H, Ishitobi H, Tanaka J, Miwa Y, Takahashi S, Ema M. Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice. Genesis. 50, 561-571, 2012.

  7. Takase H, Matsumoto H, Yamadera R, Kubota Y, Otsu A, Suzuki R, Ishitobi H, Mochizuki H, Kojima T, Takano S, Uchida K, Takahashi S, Ema M. Genome-wide identification of endothelial cell-enriched genes in the mouse embryo. Blood 120, 914-923, 2012

  8. Yoh K, Morito N, Ojima M, Shibuya K, Yamashita Y, Morishima Y, Ishii Y, Kusakabe M, Nishikii H, Fujita A, Matsunaga E, Okamura M, Hamada M, Suto A, Nakajima H, Shibuya A, Yamagata K, Takahashi S. Overexpression of RORyt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice. Eur J Immunol. 42, 1999-2009, 2012.

  9. Harada N, Ito K, Hosoya T, Mimura J, Maruyama A, Noguchi N, Yagami KI, Morito N, Maher JM, Yamamoto M, Itoh K. Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation. Free Radic Biol Med. 53, 2256-2262, 2012.

  10. Inoue A, Matsumoto I, Tanaka Y, Umeda N, Tanaka Y, Mihara M, Takahashi S, Sumida T. Murine tumor necrosis factor ƒ¿-induced adipose-related protein (tumor necrosis factor ƒ¿-induced protein 9) deficiency leads to arthritis via interleukin-6 overproduction with enhanced NF-kB, STAT-3 signaling, and dysregulated apoptosis of macrophages. Arthritis Rheum. 64,3877-3885, 2012

  11. Oishi H, Itoh S, Matsumoto K, Ishitobi H, Suzuki R, Ema M, Kojima T, Uchida K, Kato M, Miyata T, Takahashi S. Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice. J Biochem. 152,549-555, 2012

  12. Avci HX, Lebrun C, Wehrle R, Doulazmi M, Chatonnet F, Morel MP, Ema M, Vodjdani G, Sotelo C, Flamant F, Dusart I. Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor ƒ¿1 and kr?ppel-like factor 9 in Purkinje cells. Proc Natl Acad Sci U S A. 109, 14206-14211, 2012.

  13. Sano K, Katsuta O, Shirae S, Kubota Y, Ema M, Suda T, Nakamura M, Hirashima M. Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice. Biochem Biophys Res Commun. 420, 422-427, 2012.

  14. Lebrun C, Avci HX, Wehrle R, Doulazmi M, Jaudon F, Morel MP, Rivals I, Ema M, Schmidt S, Sotelo C, Vodjdani G, Dusart I. Klf9 is necessary and sufficient for Purkinje cell survival in organotypic culture. Mol Cell Neurosci. 54C, 9-21, 2012.