̘_Xg2020
  1. Fujino M, Tagami A, Ojima M, Mizuno S, Abdellatif AM, Kuno A, Takahashi S. c-Maf deletion in adult C57BL/6J mice induces cataract formation and abnormal differentiation of lens fiber cells. Exp Anim.2020 Apr 24;69(2):242-249. doi: 10.1538/expanim.19-0137. Epub 2020 Jan 21.

  2. Browning J, Rooney M, Hams E, Takahashi S, Mizuno S, Sugiyama F, Fallon PG, Kelly VP. Highly efficient CRISPR-targeting of the murine Hipp11 intergenic region supports inducible human transgene expression. Mol Biol Rep. 2020 Feb;47(2):1491-1498. doi: 10.1007/s11033-019-05204-9. Epub 2019 Dec 6.

  3. Kanai M, Jeon H, Ojima M, Nishino T, Usui T, Yadav MK, Kulathunga K, Morito N, Takahashi S, Hamada M. Phenotypic analysis of mice carrying human-type MAFB p.Leu239Pro mutation. Biochem Biophys Res Commun. 2020 Mar 5;523(2):452-457. doi: 10.1016/j.bbrc.2019.12.033. Epub 2019 Dec 25.

  4. Fuseya S, Suzuki R, Okada R, Hagiwara K, Sato T, Narimatsu H, Yokoi H, Kasahara M, Usui T, Morito N, Yamagata K, Kudo T, Takahashi S. Mice lacking core 1-derived O-glycan in podocytes develop transient proteinuria, resulting in focal segmental glomerulosclerosis. Biochem Biophys Res Commun. Biochem Biophys Res Commun. 2020 Mar 19;523(4):1007-1013. doi: 10.1016/j.bbrc.2020.01.033. Epub 2020 Jan 20. PMID: 31973821

  5. Ono Y, Tsuboi H, Moriyama M, Asashima H, Kudo H, Takahashi H, Honda F, Abe S, Kondo Y, Takahashi S, Matsumoto I, Nakamura S, Sumida T. RORγt antagonist improves Sjögren's syndrome-like sialadenitis through downregulation of CD25. Oral Dis. 2020 May;26(4):766-777. doi: 10.1111/odi.13255. Epub 2020 Mar 3. PMID: 31837283.

  6. Liu M, Tong Z, Ding C, Luo F, Wu S, Wu C, Albeituni S, He L, Hu X, Tieri D, Rouchka EC, Hamada M, Takahashi S, Gibb AA, Kloecker G, Zhang HG, Bousamra M, Hill BG, Zhang X, Yan J. Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer. J Clin Invest. 2020 Apr 1;130(4):2081-2096. doi: 10.1172/JCI131335.

  7. Le HT, Hasegawa Y, Daitoku Y, Kato K, Miznuo-Iijima S, Dinh TTH, Kuba Y, Osawa Y, Mikami N, Morimoto K, Ayabe S, Tanimoto Y, Murata K, Yagami KI, Takahashi S, Mizuno S, Sugiyama F. Generation of B6-Ddx4em1(CreERT2)Utr, a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9. Genesis.2020 Jul;58(7):e23367. doi: 10.1002/dvg.23367. Epub 2020 Apr 15.PMID: 32293787

  8. Dieterich LC, Tacconi C, Menzi F, Proulx ST, Kapaklikaya K, Hamada M, Takahashi S, Detmar M. Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis. Angiogenesis. Aug;23(3):411-423. doi: 10.1007/s10456-020-09721-1. Epub 2020 Apr 19. PMID: 32307629.

  9. Mizuno-Iijima S, Ayabe S, Kato K, Matoba S, Ikeda Y, Thi Huong Tra D, Thu Le H, Suzuki H, Nakashima K, Hasegawa Y, Hamada Y, Tanimoto Y, Daitoku Y, Iki N, Ishida M, Elsayed Ibrahim Elzeftawy A, Nakashiba T, Hamada M, Murata K, Miwa Y, Okada-Iwabu M, Iwabu M, Yagami KI, Ogura A, Obata Y, Takahashi S, Mizuno S, Yoshiki A, Sugiyama F. Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes. Methods. 2021 Jul;191:23-31. doi: 10.1016/j.ymeth.2020.04.007. Epub 2020 Apr 22.

  10. Yamazaki H, Kasai S, Mimura J, Ye P, Inose-Maruyama A, Tanji K, Wakabayashi K, Mizuno S, Sugiyama F, Takahashi S, Sato T, Ozaki T, Cavener DR, Yamamoto M, Itoh K. Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice. PLoS Genet. 2020 Apr 23;16(4):e1008693. doi: 10.1371/journal.pgen.1008693. eCollection 2020 Apr.

  11. Usui T, Morito N, Shawki HH, Sato Y, Tsukaguchi H, Hamada M, Jeon H, Yadav MK, Kuno A,Tsunakawa Y, Okada R, Ojima T, Kanai M, Asano K, Imamura Y, Koshida R,Yoh K, Usui J, Takahashi S. Transcription factor MafB in podocytes protects against the development of focal segmental glomerulosclerosis. Kidney Int. Aug;98(2):391-403. doi: 10.1016/j.kint.2020.02.038. Epub 2020 Apr 28. PMID: 32622525.

  12. Matsuzaka T, Kuba M, Koyasu S, Yamamoto Y, Motomura K, Arulmozhiraja S, Ohno H, Sharma R, Shimura T, Okajima Y, Han SI, Aita Y, Mizunoe Y, Osaki Y, Iwasaki H, Yatoh S, Suzuki H, Sone H, Takeuchi Y, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Ema M, Takahashi S, Tokiwa H, Shimano H. Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice. Hepatology. 2020 May;71(5):1609-1625. doi: 10.1002/hep.30953. Epub 2020 Feb 7.

  13. Sato T, Kataoka K, Ito Y, Yokoyama S, Inui M, Mori M, Takahashi S, Akita K, Takada S, Ueno-Kudoh H, Asahara H. Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates. eLife. 2020 May 29;9:e53608. doi: 10.7554/eLife.53608.

  14. Watahiki T, Okada K, Warabi E, Nagaoka T, Suzuki H, Ishige K, Yanagawa T, Takahashi S, Mizokami Y, Tokushige K, Ariizumi SI, Yamamoto M, Shoda J. Gender difference in development of steatohepatitis in p62/Sqstm1 and Nrf2 double-knockout mice. Exp Anim. 2020 Nov 12;69(4):395-406. doi: 10.1538/expanim.20-0028. Epub 2020 Jun 3.

  15. Morimoto K, Numata K, Daitoku Y, Hamada Y, Kobayashi K, Kato K, Suzuki H, Ayabe S, Yoshiki A, Takahashi S, Murata K, Mizuno S, Sugiyama F. Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis. Sci Rep. 2020 Jun 3;10(1):9060. doi: 10.1038/s41598-020-65986-y.

  16. Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H. Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need. Sci Rep. 2020 May 26;10(1):8676. doi: 10.1038/s41598-020-65647-0.

  17. Honda T, Takata Y, Cherasse Y, Mizuno S, Sugiyama F, Takahashi S, Funato H, Yanagisawa M, Lazarus M, Oishi Y. Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine D2R-mediated Sleep Reduction. iScience. 2020 Jun 26;23(6):101240. doi: 10.1016/j.isci.2020.101240. Epub 2020 Jun 4. PMID: 32563157.

  18. Deng Z, Matsumoto Y, Kuno A, Ojima M, Xiafukaiti G, Takahashi S.An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition. Int. J. Mol. Sci. 2020, 21(16), 5606; https://doi.org/10.3390/ijms21165606.

  19. Nakai A, Fujiyama T, Nagata N, Kashiwagi M, Ikkyu A, Takagi M, Tatsuzawa C, Tanaka K, Kakizaki M, Kanuka M, Kawano T, Mizuno S, Sugiyama F, Takahashi S, Funato H, Sakurai T, Yanagisawa M, Hayashi Y. Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β. Genetics.2020 Nov;216(3):753-764. doi: 10.1534/genetics.120.303435. Epub 2020 Sep 2.

  20. Suzuki T, Uruno A, Yumoto A, Taguchi K, Suzuki M, Harada N, Ryoke R, Naganuma E, Osanai N, Goto A, Suda H, Browne R, Otsuki A, Katsuoka F, Zorzi M, Yamazaki T, Saigusa D, Koshiba S, Nakamura T, Fukumoto S, Ikehata H, Nishikawa K, Suzuki N, Hirano I, Shimizu R, Oishi T, Motohashi H, Tsubouchi H, Okada R, Kudo T, Shimomura M, Kensler TW, Mizuno H, Shirakawa M, Takahashi S, Shiba D, Yamamoto M. Nrf2 contributes to the weight gain of mice during space travel. Commun Biol. 2020 Sep 8;3(1):496. doi: 10.1038/s42003-020-01227-2.

  21. Fujimoto D, Kuwabara T, Hata Y, Umemoto S, Kanki T, Nishiguchi Y, Mizumoto T, Hayata M, Kakizoe Y, Izumi Y, Takahashi S, Mukoyama M. Suppressed ER-associated degradation by intraglomerular cross talk between mesangial cells and podocytes causes podocyte injury in diabetic kidney disease. FASEB J.2020 Nov;34(11):15577-15590. doi: 10.1096/fj.202000078RR. Epub 2020 Sep 30.

  22. Tanaka R, Ichimura Y, Kubota N, Saito A, Nakamura Y, Ishitsuka Y, Watanabe R, Fujisawa Y, Kanzaki M, Mizuno S, Takahashi S, Fujimoto M, Okiyama N. Activation of CD8 T cells accelerates anti-PD-1 1 antibody-induced psoriasis-like dermatitis through IL-6. Commun Biol. 2020 Oct 15;3(1):571. doi: 10.1038/s42003-020-01308-2.

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