Publication 2025

1. Nguyen CLK, Kuba Y, Le HT, Shawki HH, Mikami N, Aoki M, Yasuhara N, Suzuki H, Mizuno-Iijima S, Ayabe S, Osawa Y, Fujiyama T, Dinh TTH, Ishida M, Daitoku Y, Tanimoto Y, Murata K, Kang W, Ema M, Hirao Y, Ogura A, Takahashi S, Sugiyama F, Mizuno S. Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice. Cell Death Discov. 2025 Jan 20;11(1):17. doi: 10.1038/s41420-025-02291-5.


2. Kayama E, Baoshuo N, Tatsuno R, Nishi K, Mohammed ESI, Abiko Y, Yanagawa T, Takahashi S, Warabi E. 4-Hydroxy-2-nonenal causes nuclear accumulation of p62 by inhibiting Xpo1 and promoting the proteolytic pathway in the nucleus. PLoS One. 2025 Feb 3;20(2):e0316558. doi: 10.1371/journal.pone.0316558. eCollection 2025. PMID: 39899539.


3. Yamada Y, Sadahiro T, Nakano K, Honda S, Abe Y, Akiyama T, Fujita R, Nakamura M, Maeda T, Kuze Y, Onishi M, Seki M, Suzuki Y, Takeuchi C, Iwasaki YW, Murano K, Sakata-Yanagimoto M, Chiba S, Kato H, Sakamoto H, Hiramatsu Y, Ieda M. Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction. Circulation. 2025 Feb 11;151(6):379-395. doi: 10.1161/CIRCULATIONAHA.123.067504.


4. Casco-Robles MM, Echigoya T, Shimazaki T, Murakami Y, Hirano M, Maruo F, Mizuno S, Takahashi S, Chiba C. One-step Cre-loxP organism creation by TAx9. Commun Biol. 2025 Mar 6;8(1):340. doi: 10.1038/s42003-025-07759-9.


5. Park S, Yoon K, Hong E, Kim MW, Kang MG, Mizuno S, Kim HJ, Lee MJ, Choi HJ, Heo JS, Bae JB, An H, Park N, Park H, Kim P, Son M, Pang K, Park JY, Takahashi S, Kwon YJ, Kang DW, Kim SJ. Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation. Bone Res. 2025 Mar 24;13(1):40. doi: 10.1038/s41413-025-00419-y.


6. Tsuji R, Hayashi T, Takahashi S, Asakura A, Fujita R. The Multifaceted Role of MyoD in Adult Skeletal Muscle: Homeostasis, Regeneration, and Diseases. Am.J.Physiol-Cell Physiol. 2025 Jun 05.https://doi.org/10.1152/ajpcell.00334.2025


7. Sato T, To K, Sakurai F, Chihara K, Warabi E, Isobe T, Suzuki H, Shoda J, Okada K. Intestinal epithelial cell-specific restoration of Nrf2 gene in whole-body-knockout mice ameliorates acute colitis. Exp Anim. 2025 Jul 11;74(3):335-347. doi: 10.1538/expanim.24-0152.


8. Sadaki S, Tsuji R, Hayashi T, Watanabe M, Iwai R, Wenchao G, Semenova AE, Sultanov RI,Zhelankin VA, Generozov EV, Ahmetov II, Sakakibara I, Ojima K, Sakurai H, Muratani M, Kudo T, Takahashi S & Fujita R. Large MAF transcription factors reawaken evolutionarily dormant fast-glycolytic type IIb myofibers in human skeletal muscle. Skeletal Muscle, 2025 July 26; 15(19),doi:10.1186/s13395-025-00391-5.


9. Chen W, Wang J, Warabi E, Imasaka M, Takeda Y, Nishiura H, Takahashi S, Ohmuraya M. P62/Sequestosome1 deficiency disrupts antioxidant and stress homeostasis during acute pancreatitis without exacerbating inflammation. Pancreatology. 2025 Aug 11:S1424-3903(25)00573-3. doi: 10.1016/j.pan.2025.07.416.


10. Watabe Y, Kobayashi S, Takahashi S, Yoshihara M. Computer identification of Notch3 in the neurogenic progenitor cells of mammalian early optic vesicles.BMC Res Notes. 2025 Aug 21;18(1):367. doi: 10.1186/s13104-025-07440-8. PMID: 40836356.


11. Saiga H, Ueno M, Tamura T, Tsujimura Y, Asaka MN, Tsukamoto Y, Mukai T, Hamada M, Takahashi S, Tanaka T, Kaisho T, Takahashi Y, Hoshino K, Ato M. Mycobacterium tuberculosis impairs protective cytokine production via transcription factor MafB manipulation. PLoS Pathog. 2025 Sep 4;21(9):e1013476. doi: 10.1371/journal.ppat.1013476.


12. Horiuchi T, Kaneko K, Hosaka S, Uno K, Tomiyama S, Takahashi K, Yamato M, Endo A, Sugawara H, Kawana Y, Asai Y, Kodama S, Imai J, Mizuno S, Takahashi S, Takasaki A, Ono H, Yokote K, Maeda R, Sugiura Y, Katagiri H. Redox-dependent liver gluconeogenesis impacts different intensity exercise in mice. Nat Metab. 2025 Sep 18. doi: 10.1038/s42255-025-01373-z.


13. Okamura E, Matsumoto S, Suzuki H, Tanimoto Y, Dinh TTH, Mikami N, Muto M, Matsumoto T, Sugiyama F, Takahashi S, Woltjen K, Mizuno S, Ema M. Efficient generation of single copy transgenic mice using piggyBat transposase from the little brown bat Myotis lucifugus. Biol Reprod. 2025 Oct 13:ioaf235. doi: 10.1093/biolre/ioaf235.


14. Hachiya K, Mizunoe Y, Yang JJ, Uchida Y, Fukai H, Esashi T, Nozaki Y, Mizuno S, Takahashi S, Kobayashi M, Higami Y. PARIS/ZNF746 DNA-binding domain deficiency promotes adipose tissue hyperplasia and hepatic lipid accumulation. Sci Rep. 2025 Oct 15;15(1):36095. doi: 10.1038/s41598-025-19977-6.


15. Asano S, Liao CW, Matsunaga Y, Jeon H, Sawaguchi K,Asano K, Kusakabe M, Shahri ZJ, Gogoleva N, Yokomizo T, Takahashi S,Hamada M. MAFB regulates hematopoietic stem cell proliferation and maintenance. Sci Rep. 2025 Nov 15: 40592, doi: 10.1038/s41598-025-24389-7.


16. Hashiguchi A, Watanabe KN, Takahashi S. Assessing the impact of Japanese team grants in plant science. Plant Cell Physiol. 2025 Nov 21:pcaf153. doi: 10.1093/pcp/pcaf153.