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分子レベルでウイルス感染症を理解する
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筑波大学 医学医療系
Faculty of Medicine, University of Tsukuba

研究業績PUBLICATION


2012年
                                     

Kawaguchi A, Matsumoto K, Nagata K.
YB-1 functions as a porter to lead influenza virus ribonucleoprotein complexes to microtubules.
J. Virol., 86(20): 11086-110895.

Onomoto K, Jogi M, Yoo JS, Narita R, Morimoto S, Takemura A, Sambhara S, Kawaguchi A, Osari S, Nagata K, Matsumiya T, Namiki H, Yoneyama M, Fujita T.
Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity.
PLoS One, 7(8): e43031.

Tojino M, Mori M, Kasuya MC, Hatanaka K, Kawaguchi A, Nagata K, Shirai T, Mizuno M.
Immobilization of fluorous oligosaccharide recognized by influenza virus on polytetrafluoroethylene filter.
Bioorg. Med. Chem. Lett., 22(2): 1251-1254.

Fukuoka M, Minakuchi M, Kawaguchi A, Nagata K, Kamatari YO, Kuwata K.
Structure-based discovery of anti-influenza virus A compounds among medicines.
Biochim. Biophys. Acta., 1820(2): 90-95.

2011年                                   
Kawaguchi A, Momose F, Nagata K.
Replication-coupled and host factor-mediated encapsidation of the influenza virus genome by viral nucleoprotein.
J. Virol., 85(13): 6197-6204.

Momose F, Sekimoto T, Ohkura T, Jo S, Kawaguchi A, Nagata K, Morikawa Y.
Apical transport of influenza A virus ribonucleorptein requires Rab11-positive recycling endosome.
PLoS One, 6(6): e21123.

2010年                                  
Takagi M, Motohashi K, Nagai A, Izumikawa M, Tanaka M, Fuse S, Doi T, Iwase K, Kawaguchi A, Nagata K, Takahashi T, Shin-ya K.
Anti-influenza virus compound from Streptomyces sp. Rl18.
Org. Lett., 12(20): 4664-4666.

Jo S, Kawaguchi A, Takizawa N, Morikawa Y, Momose F, Nagata K.
Involvement of vesicular trafficking system in membrane targeting of the progeny influenza virus genome.
Microbes Infect., 12(12-13): 1079-1084.

Kato T, Kawaguchi A, Nagata K, Hatanaka K.
Development of tetraphenylethylene-based fluorescent oligosaccharide probes for detection of influenza virus.
Biochem. Biophys. Res. Commun., 394(1): 200-204.

Kawaguchi A, Wakai C, Nagata K.
Host factors involved in regulation of the influenza virus replication.
Tanpakushitsu Kaksan Koso, 54(8 Suppl): 926-933.  (Review)

Naito T, Kawaguchi A, Nagata K.
Function of influenza virus RNApolymerase based on structure.
Uirusu, 59(1):1-11.  (Review)

2009年                                  
Sugiyama K, Obayashi E, Kawaguchi A, Suzuki Y, Tame JR, Nagata K, Park SY.
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase.
EMBO J., 28(12): 1803-1811.

2008年                                   
Obayashi E, Yoshida H, Kawai F, Shibayama N, Kawaguchi A, Nagata K, Tame JR, Park SY.
The structural basis for an essential subunit interaction in influenza virus RNA polymerase.
Nature, 454(7208): 1127-1131.

Nagata K, Kawaguchi A, Naito T.
Host factors for replication and transcription of the influenaza virus genome.
Rev. Med. Virol., 18(4):247-260.  (Review)

2007年                                   
Kawaguchi A, Nagata K.
De novo replication of the influenza virus RNA genome is regulated by a DNA replicative helicase, MCM.
EMBO J., 26(21): 4566-4575.

Naito T, Momose F, Kawaguchi A, Nagata K.
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits.
J. Virol., 81(3): 1339-1349.

2006年                                  
Kawaguchi A, Nagata K.
Molecular mechanism of replication and transcritpion of the infleunza virus genome and host factors.
Uirusu, 56(1): 99-108.   (Review)

2005年                                  
Kawaguchi A, Naito T, Nagata K.
Involvement of influenza virus PA subunit in assembly of functional RNA polymerase complexes.
J. Virol., 79(2): 732-744.




連絡先

〒305-8575
茨城県つくば市天王台1−1−1
筑波大学 医学医療系感染生物学
(分子ウイルス学)

TEL 029-853-3942
FAX 029-853-3942