Transcription plays a central role in gene expression, which affects various aspects of biological phenomena in normal or diseased states.
Our group is interested in the mechanisms of transcriptional regulation—how transcription factors, coactivators, general transcription factors and chromatin regulate transcription at the molecular level. We are particularly interested in chromatin remodeling and modifications as well as their functional consequences on transcription, a process that is intimately linked to epigenetics.
The transcription and chromatin field is an exciting and rapidly progressing area. We provide a competitive, yet enjoyable environment for graduate students who are passionate and committed to research in biomedical sciences.
- 2024.1.25
- Rin Zamami joined our research group.
- 2024.1.16
- Our paper about the Sendai virus vectors that can be controled by ligand-responsive endoribonuclease Csy4 has been published in Journal of Biological Engineering.
- 2023.12.1
- Taiyi Tang joined our research group.
- 2023.8.31
- Our paper about discovery of SOX9 variants which promotes chondrocyte differentiation has been published in Stem Cells.
- 2023.4.1
- Yu Okubo joined our research group.
- 2023.3.25
- Arun Kumar Burramsetty received the Ph.D., and Takumi Kishimoto received the Master’s Degree in Medical Sciences.
- 2022.11.30
- Our paper about regulators relevant to pluripotency of mouse ES cells and reprogramming of somatic cells has been published in International journal of molecular sciences.
- 2022.10.1
- Osei Mensah Emmanuel and Jianheng Duan joined our research group.
- 2022.9.25
- Phuong Hoang Anh Le received the Ph.D.
- 2022.6.1
- Zezhen Meng and Zhengda Han joined our research group.
- 2022.4.29
- Our paper about a novel regulator of reprogramming has been published in Stem Cells.
- 2022.4.1
- Yudai Ibaraki and Yujiro Kato joined our research group.
- 2022.3.25
- Shiho Aizawa received the Ph.D., and Jingwen Zhou and Seminario Mondejar Gonzalo Alfredo received the Master’s Degree in Medical Sciences.
- 2022.1.11
- Our paper about X chromosome reactivation during reprogramming has been published in Stem Cell Reports.
- 2021.9.25
- Muhammad Hamzah received the Master’s Degree in Medical Sciences.
- 2021.9.23
- Our collaboration paper about development of a time-lapse ultra-multiplex CARS microspectroscopy to visualize intracellular lipid metabolism in brown adipocytes by has been published in Journal of Chemical Physics.
- 2021.4.1
- Satoshi Kuwahara and Yuko Nishizawa joined our research group.
- 2021.3.25
- Anju Doi, TaKahiro Yamanaka and Syuto Okachi received the Master’s Degree in Medical Sciences. Also, Takumi Kishimoto received the Bachelor's degree in Medical Sciences from the University of Tsukuba.
- 2021.2.4
- Ziwei Jiang joined our research group.