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1-1-1 tennodai,tsukuba-shi,ibaraki-ken 305-8575, JAPAN
Laboratory of Gene Regulation
Graduate School of Comprehensive Human Sciences
University of Tsukuba

Research Overview

Transcription plays a central role in gene expression, which affects various aspects of biological phenomena in normal or diseased states.

Our group is interested in the mechanisms of transcriptional regulation—how transcription factors, coactivators, general transcription factors and chromatin regulate transcription at the molecular level. We are particularly interested in chromatin remodeling and modifications as well as their functional consequences on transcription, a process that is intimately linked to epigenetics.

The transcription and chromatin field is an exciting and rapidly progressing area. We provide a competitive, yet enjoyable environment for graduate students who are passionate and committed to research in biomedical sciences.

NEWS&TOPICS
2017.4.3
Arun B Kumar, Rie Hirai and Miho Takami joined our research group.
2017.4.3
An open campus for master's program will be held on April 22 (Sat).
2017.3.24
Shiho Aizawa received the Master’s Degree in Medical Sciences.
2017.3.2
The paper demonstrating that KLF4 promotes TCL1-dependent metabolic change during iPSC induction was published in Stem Cell Reports.
2016.10.28
The paper demonstrating that the BMP-SMAD-ID signaling promotes reprogramming by suppressing p16/INK4A-mediated cell senescence was published in Pro Natl Aca Sci USA.
2016.10.7
Li Jingyue joined our research group.
2016.10.1
Le Phuong Hoang Anh and Borisova Dmitrievna Evgeniia joined our research group.
2016.9.23
Nguyen Thuy Linh and Nugroho Fransiska Liliani received the Master’s Degree in Medical Sciences.
2016.4.7
An open campus for master's program will be held on June 18 (Sat).
2016.4.7
An open campus for master's program will be held on April 23 (Sat).
2016.4.1
Dr. Yohei Hayashi joined our research group as a new assistant professor.
2016.3.25
Ryota Kobayashi received the Master’s Degree in Medical Sciences, and Shiho Honda received the Bachelor's degree in Medical Sciences from the University of Tsukuba.
2015.12.1
Dr. Hisatake presented our research results at the 38th annual meeting of MBSJ (Kobe).
2015.10.1
Tran Vo Kieu Nhi joined our research group.
2015.9.25
Bui Phuong Linh received the Master’s Degree in Medical Sciences from the University of Tsukuba.
2015.9.17
The paper demonstrating the role for the NF complexes as coactivators was published in the Journal of Biological Chemistry.
2015.9.8
Dr. Nishimura gave an invited talk at the meeting on Gene-editing, transgenics & stem cells: Frontiers in medical and molecular therapeutics (Ireland).
2015.7.31
A paper co-authored with our research collaborators was published in Stem Cell Reports.
2015.6.25
Dr. Nishimura presented our research findings at the International Society of Stem Cell Research 13th Annual Meeting (Sweden).
2015.6.1
An open campus for the master’s program will be held in June 20th (Sat), in which our lab activities will be introduced.
2015.4.16
An open campus for master's program will be held on April 25 (Sat).
2015.4.1
Shiho Aizawa and Shiho Honda joined our research group.
2015.3.25
Mr. Kato and Ms. Shiomitsu received the master's degree in medical sciences from University of Tsukuba.
2015.3.21
Mr. Kato, Ms. Shiomitsu and Dr. Nishimura presented their research results at the 14th Congress of the Japanese Society for Regenerative Medicine (Yokohama).
2014.11.25
Dr. Nishimura presented his research results at the 37th annual meeting of MBSJ (Yokohama).
2014.11.25
Dr. Roeder (The Rockefeller University) was invited to give a research seminar.
2014.10.6
Kaisar Dauyey joined our research group.
2014.10.2
The paper by Nishimura et al has been published in Stem Cell Reports.
2014.9.26
Tran Thi Hai Yen, Nguyen Thuy Linh and Nugroho Fransiska Liliani joined our research group.
2014.7.25
Mr. Lalhaba Oinam received the bachelor's degree in medical sciences from University of Tsukuba.
2014.7.14
The article about the functional analysis of a transcription coactivator hnRNP R was published in IGAKU no AYUMI (Japanese).
2014.4.1
Chen Chen joined our research group.
2014.3.25
Mr. Ayakawa and Mr. Kobayashi received the bachelor's degree in medical sciences from University of Tsukuba.
2014.3.6
Dr. Nishimura and Mr. Kato presented their research results at the 13th Congress of the Japanese Society for Regenerative Medicine (Kyoto).
2013.12.21
Ms. Shiomitsu presented her research data at the 12th NTU-KYOTO U-U of TSUKUBA Joint Mini-Symposium 2013 (Taiwan) and received the outstanding award in poster presentation.
2013.12.5
Dr. Chiang (University of Texas Southwestern Medical Center, USA) was invited to give a research seminar.
2013.12.3
Dr. Nishimura and Mr. Kato presented their research results at the 36th annual meeting of MBSJ (Kobe).
2013.11.18
Dr. Ohkuma (University of Toyama) was invited to give a research seminar.
2013.10.14
Dr. Nishimura presented our research results at the CSHAsia 2013 Conference on CSHA/ISSCR Joint Meeting on Stem Cells in Science and Medicine (Suzhou Dushu Lake Conference Center, China).
2013.9.25
Dr. Hisatake presented our research results at the Cold Spring Harbor meeting on Stem Cell Biology (New York, USA).
2013.9.24
Bui Phuong Linh joined our research group.
2013.8.13
The paper by Fukuda et al has been published in PLOS ONE.
2013.6.14
Dr. Nishimura presented his research results at the International Society of Stem Cell Research 11th Annual Meeting (Boston).
2013.4.27
An open campus for master's program will be held on June 22 (Sat).
2013.4.1
Emi Shiomitsu, Daisuke Ayakawa and Ryota Kobayashi joined our research group.
2012.12.12
Dr. Fukuda presented her research results at the 35th annual meeting of MBSJ. (Fukuoka).
2012.12.1
Lalhaba Oinam and Tomoko Nishimura joined our research group.
2012.4.1
Tetsuo Kato joined our research group.
2011.12.16
Dr. Takahashi (Hokkaido University) was invited to give a research seminar.
2011.12.15
Dr. Fukuda and Dr. Nishimura presented thier research results at the 34th annual meeting of MBSJ (Yokohama).
2011.11.12
Dr. Nishimura presented his research results at the NTU-JST Joint Meeting on RNA and Biofunctions (Taiwan).
2011.11.1
Dr. Nishimura presented his research results at the 2nd Leading Graduate Schools International Conference (Tsukuba).
2011.11.1
Yu Minagawa joined our research group.
2011.8.31
Dr. Fukuda presented her research results at the Cold Spring Harbor meeting (New York, USA).
2010.7.xx
Our website is renewed.
2010.7.3
The fair for Frontier Medical Sciences (Master’s course) is held.
2010.6.4
An opening is available for assistant professorship; application deadline is 7/30.
For details, see
2010.4.1
The lab is renovated as a part of anti-seismic reinforcement.
2010.3.26
Our paper by Shimada et al is published in J. Biol. Chem.