Contact

1-1-1 tennodai,tsukuba-shi,ibaraki-ken 305-8575, JAPAN
Laboratory of Gene Regulation
Graduate School of Comprehensive Human Sciences
University of Tsukuba

Research Overview

Transcription plays a central role in gene expression, which affects various aspects of biological phenomena in normal or diseased states.

Our group is interested in the mechanisms of transcriptional regulation—how transcription factors, coactivators, general transcription factors and chromatin regulate transcription at the molecular level. We are particularly interested in chromatin remodeling and modifications as well as their functional consequences on transcription, a process that is intimately linked to epigenetics.

The transcription and chromatin field is an exciting and rapidly progressing area. We provide a competitive, yet enjoyable environment for graduate students who are passionate and committed to research in biomedical sciences.

NEWS&TOPICS
2021.4.1
Satoshi Kuwahara and Yuko Nishizawa joined our research group.
2021.3.25
Anju Doi, TaKahiro Yamanaka and Syuto Okachi received the Master’s Degree in Medical Sciences. Also, Takumi Kishimoto received the Bachelor's degree in Medical Sciences from the University of Tsukuba.
2021.2.4
Ziwei Jiang joined our research group.
2020.4.1
Yukino Sasahara joined our research group.
2020.3.25
Bui Phuong Linh received the Ph.D., and Yuya Sekiguchi, Miho Takami and Li Jingyue received the Master’s Degree in Medical Sciences. Also, Seminario Mondejar Gonzalo Alfredo received the Bachelor's degree in Life Sciences from the University of Tsukuba.
2019.11.15
Our paper about the non-invasive in vivo imaging mice for UCP1 expression has been published in PLOS ONE.
2019.11.12
Our paper about the novel factor for retroviral silencing during Reprogramming has been published in Cell Reports.
2019.10.1
Muhammad Hamzah, Jingwen Zhou and Siru Su joined our research group.
2019.9.25
Chiu Chen-Hsiang received the Master’s Degree in Medical Sciences.
2019.5.7
Our paper (review) about the metabolic shift during somatic cell reprogramming has been published in International Journal of Molecular Sciences.
2019.4.17
April 20 (Sat) is the campus open day for Master's program.
2019.4.1
Syuto Okachi and Takumi Kishimoto joined our research group.
2019.3.25
Tran Thi Hai Yen received the Ph.D., and Rie Hirai received the Master’s Degree in Medical Sciences. Also, Anju Doi and Takahiro Yamanaka received the Bachelor's degree in Medical Sciences from the University of Tsukuba.
2019.2.11
Our paper about the development of an imaging system to evaluate the quarity of pluripotent stem cells has been published in Scientific Reports.
2018.9.21
Yuya Sekiguchi presented his research about functional analysis of SOX9 variants in chondrocyte differentiation at the Tsukuba Global Science Week 2018 and received the Outstanding Poster Award.
2018.7.24
Our paper showing live cell imaging of X chromosome reactivation during reprogramming has been published in Biochemistry and Biophysics Reports.
2018.5.8
An open campus for master's program will be held on June 23 (Sat).
2018.4.1
Anju Doi and Takahiro Yamanaka joined our research group.
2018.4.1
An open campus for master's program will be held on April 21 (Sat).
2018.3.25
Shiho Honda received the Master’s Degree in Medical Sciences, and Yuya Sekiguchi, Miho Takami and Li Jingyue received the Bachelor's degree in Medical Sciences from the University of Tsukuba.
2017.11.1
An open campus for master's program will be held on December 2 (Sat).
2017.10.1
Chiu Chen-Hsiang joined our research group.
2017.9.22
Tran Vo Kieu Nhi received the Master’s Degree in Medical Sciences.
2017.4.3
Arun B Kumar, Rie Hirai and Miho Takami joined our research group.
2017.4.3
An open campus for master's program will be held on April 22 (Sat).