Our major goals are to understand the mechanism of the intractable disease and establish the therapy of the disease through the several Stem Cells biology.
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2023/2/22
"Chemically defined cytokine-free expansion of human haematopoietic stem cells" was published in "Nature".
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Sakurai M, Ishitsuka K, Ito R, Wilkinson AC, Kimura T, Mizutani E, Nishikii H, Sudo K, Becker HJ, Takemoto H, Sano T, Kataoka K, Takahashi S, Nakamura Y, Kent DG, Iwama A, Chiba S, Okamoto S, Nakauchi H, Yamazaki S.
Chemically defined cytokine-free expansion of human haematopoietic stem cells.
Nature 2023 Feb
Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M.
Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.
Nature 2022 Nov
Che JLC, Bode D, Kucinski I, Cull AH, Bain F, Becker HJ, Jassinskaja M, Barile M, Boyd G, Belmonte M, Zeng AGX, Igarashi KJ, Rubio-Lara J, Shepherd MS, Clay A, Dick JE, Wilkinson AC, Nakauchi H, Yamazaki S,
Göttgens B, Kent DG. Identification and characterization of in vitro expanded hematopoietic stem cells.
EMBO Rep 2022 Aug
Itokawa N, Oshima M, Koide S, Takayama N, Kuribayashi W, Nakajima-Takagi Y, Aoyama K, Yamazaki S, Yamaguchi K, Furukawa Y, Eto K, Iwama A.
Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells.
Nat Commun 2022 May
Osaki J, Yamazaki S, Hikita A, Hoshi K
Hematopoietic progenitor cells specifically induce a unique immune response in dental pulp under conditions of systemic inflammation.
Heliyon. 2022 Feb
