日本語(Jp)
/
英語(En) 

Integrated Study on Health Information

Ohniwa lab

Top Research Products Recruitment Members  Contact
  Research Products


   1.Bridge between scientific and east-Asian methodologies

   2.Utilization of big data

   3.Science communication

   4.Approach to business

   5.Evidence-based science to life and health

   6.Solution from academic diplomat



1.Bridge between scientific and east-Asian methodologies

Ohniwa RL Reconsidering Kata (型) (2021) total 246 pages, Kyoto Univeristy Press

・Ohniwa RL., "Approach to ", Environmental Forum, 150-157, 2019

Ohniwa RL., "Approach to life: "Kata (型, Form)" and design thinking", Environmental Forum, 150-157, 2019


2.Utilization of big data

  ・Ohniwa RL, Takeyasu K, and Hibino A. “Researcher dynamics in the generation of Emerging Topics in life sciences and medicine” Scientometrics, DOI :10.1007/s11192-021-04233-1 (2022).

  ・Ohniwa RL, Kijima J, Fukushige M, and Ohneda O. “COVID-19 As a Research Dynamics Transformer: Emerging Cross-Disciplinary and National Characteristics.” Front Big Data, 4, Article631073, DOI :10.3389/fdata.2021.631073. (2021)

  ・Ohniwa RL, and Hibino A. “Generating process of Emerging Topics in the life sciences.” Scientometrics, 121(3), 1549-1561, DOI :10.1007/s11192-019-03248-z. (2019)

・Ohniwa RL, Hibino A and Takeyasu K. “Trends in research foci in life science fields over the last 30 years monitored by emerging topics” Scientometrics, 85, 111-127 (2010)

・大庭良介(2009)データマイニングからの接近―「抽出する」―,山口富子・日比野愛子編『萌芽する科学技術』, 第4章, 105-161, 京都大学出版会(2009)

・Ohniwa RL, Hibino A and Takeyasu K. “Perspective Factor; Past, Present and Future of Life Sciences.” PROCEEDINGS OF International Society for Scientometrics and Infometrics 2007, II, 908-909 (2007)

・Ohniwa RL, Denawa M, Kudo M, Nakamura K and Takeyasu K. “Perspective Factor; A novel indicator for the assessment of journal quality.” Research Evaluation, 13 (3), 175-180 (2004)

・大庭良介(2003)研究評価のための新たな指標~パースペクティブファクター:季刊生命誌36号


3.Science communication

  ・Ho K, Mayers T, Morikawa K, Watanabe Y, Ohniwa R, Saito S, Muratani M, Hasegawa H, Thao DTP, Wanandi SI, and Ohneda O. “Advanced Topics in Biotechnology and Medicine: An intensive literature-based course to encourage critical thinking in science and build academic English skills”. J Med Eng Edu., 20(3), 39-46 (2021)

UT Athlete Restaurant (2020, online)

The development of magnet items to guide how to cook foodstuffs (for UT Athlete Restaurant 2020)




4.Approach to business

・Takero Kurosawa. "Sunburn Recovery Drink". Tsukuba Global Science Week 2018(2018年つくば市)





5.Evidence-based science to life and health

・Lin YY, Li MH, Chang YC, Fu PY, Ohniwa RL, Li HW, Lin JJ. “Dynamic DNA shortening by telomere-binding protein Cdc13”. J Am Chem Soc (2021) DOI: 10.1021/jacs.1c00820

・Mori K, Ohniwa RL, Takizawa N, Naito T, Saito M. “Development of a Genetically Stable Live Attenuated Influenza Vaccine Strain using an Engineered High-Fidelity Viral Polymerase”. J Virol. JVI.00493-21. doi: 10.1128/JVI.00493-21. (2021)

・Gor V, Hoshi M, Takemura AJ, Higashide M, Romero VM, Ohniwa RL, and Morikawa K “Virulence Reversion in Staphylococcus aureus”. Proceedings in MDPI in 1st International Electronic Conference on Microbiology, doi: 10.3390/ECM2020-07101 (2020)

・Gor V, Hoshi M, Takemura AJ, Higashide M, Romero VM, Ohniwa RL, and Morikawa K. “Prevalence of Agr phase variants in Staphylococcus aureus”. Access Microbiology, 2(7), doi.org/10.1099/acmi.ac2020.po0002. (2020)

・Morikawa K, Ushijima Y, Ohniwa RL, Miyakoshi M, Takeyasu K. “What Happens in the Staphylococcal Nucleoid under Oxidative Stress?” Microorganisms. Nov 29;7(12). pii: E631. doi: 10.3390/microorganisms7120631. Review. (2019)

  ・Naito T, Shirai K, Mori K, Muratsu H, Ushirogawa H, Ohniwa RL, Hanada K, Saito M. “Tyr82 Amino Acid Mutation in PB1 Polymerase Induces an Influenza Virus Mutator Phenotype.” J Virol. 2019 Aug 28. pii: JVI.00834-19. doi: 10.1128/JVI.00834-19. [Epub ahead of print](2019)

   ・Gor V, Takemura AJ, Nishitani M, Higashide M, Medrano VR, Ohniwa RL, Morikawa K. “Finding of Agr Phase Variants in Staphylococcus aureus.” mBio. 10(4):e00796-19 (2019)

  ・Chuang MC, Lin SS, Ohniwa RL, Lee GH, Su YA, Chang YC, Tang MJ, Liu YW. “Tks5 and Dynamin-2 enhance actin bundle rigidity in invadosomes to promote myoblast fusion.” J Cell Biol. pii: jcb.201809161. doi: 10.1083/jcb.201809161. [Epub ahead of print] (2019)

・Hsu CC, Hsu RB, Ohniwa RL, Chen JW, Yuan CT, Chia JS, and Jung CJ. “Neutrophil Extracellular Traps Enhance Staphylococcus Aureus Vegetation Formation through Interaction with Platelets in Infective Endocarditis.” Thromb Haemost. doi: 10.1055/s-0039-1678665. [Epub ahead of print] (2019)

・Nguyen LTT, Takemura AJ, Ohniwa RL, Saito S, Morikawa K. “Sodium Polyanethol Sulfonate Modulates Natural Transformation of SigH-Expressing Staphylococcus aureus.” Curr Microbiol. doi: 75(4):499-504. (2018)

  ・Ohniwa RL, Maruyama H, Morikawa K, and Takeyasu K. “Atomic Force Microscopy Imaging and Analysis of Prokaryotic Genome Organization”, Methods Mol Biol. 1837:147-160. doi: 10.1007/978-1-4939-8675-0_9. (2018)

・Ushijima Y, Ohniwa RL*, and Morikawa K. “Identification of nucleoid associated proteins (NAPs) under oxidative stress in Staphylococcus aureus.”(*corresponding author) BMC Microbiol. 17(1):207. doi: 10.1186/s12866-017-1114-3. (2017)

・Naito T, Mori K, Ushirogawa H, Takizawa N, Nobusawa E, Odagiri T, Tashiro M, Ohniwa RL, Nagata K, Saito M. “Generation of a genetically stable high-fidelity influenza vaccine strain.” J Virol. 2017 Jan 4. pii: JVI.01073-16. doi: 10.1128/JVI.01073-16. (2017)

・Ushijima Y, Yoshida O, Villanueva MJ, Ohniwa RL and Morikawa K. “Nucleoid clumping is dispensable for the Dps-dependent hydrogen peroxide resistance in Staphylococcus aureus.” Microbiology. 2016 Aug 17. 162(10):1822-1828. doi: 10.1099/mic.0.000353. (2016)

・Ushijima Y, Ohniwa RL, and Morikawa K. “In vitro DNA Protection Assay Using Oxidative Stress,” Bio-protocol, 5(14), e1538. (2015)

・Mori K, Murano K, Ohniwa RL, Kawaguchi A and Nagata K. “Tamiflu Expands Quasispecies of Influenza Virus through Cell-to-cell Transmission.” Scientific Report, 16(5), 9163 (2015)

・Maudsdotter L, Imai S, Ohniwa RL, Saito S and Morikawa K. “Staphylococcus aureus dry stress survivors have a heritable fitness advantage in subsequent dry exposure.” Microbes and Infection, pii: S1286-4579(15)00038-6 (2015)

・Suwastika NI, Denawa M, Yomogihara S, Im CH, Bang WY, Ohniwa RL, Bahk JD, Takeyasu K and Shiina T. “Evidence for Lateral gene Transfer (LGT) in the evolution of eubacteria-derived small GTPases in plant organelles.” Frontiers in Plant Science, 5678, doi: 10.3389/fpls.2014.00678 (2014)

・Ushijima Y, Ohniwa RL, Maruyama A, Saito S, Tanaka Y and Morikawa K. “Nucleoid compaction by MrgAAsp56Ala/Glu60Ala does not contribute to staphylococcal cell survival against oxidative stress and phagocytic killing by macrophage.” FEMS Microbiol Lett, 360(2), 144-51 (2014)

・Ohniwa RL, Muchaku H, Saito S, Wada C and Morikawa K. “Atomic force microscopy analysis of the role of major DNA-binding proteins in organization of the nucleoid in Escherichia coli.” PLoS ONE, 8(8), e72954 (2013)

   ・大庭良介 表層常在細菌叢と病原体「環境と微生物の事典」朝倉書店, p252-253 (2014)

   ・大庭良介 酸化ストレス耐性 「環境と微生物の事典」朝倉書店, p260 (2014)

   ・Maruyama H, Ohniwa R, Prieto E, Takeyasu K. Chapter 14. Genome folding mechanisms in the three domains of life revealed by AFM in "AFM in Nanobiology" (Edited by Takeyasu K), Pan Stanford Publishing , ISBN 9789814411585 (2014)

・Ueta M, Wada C, Daifuku T, Sako Y, Bessho Y, Kitamura A, Ohniwa RL, Morikawa K, Yoshida H, Kato T, Miyata T, Namba K and Wada A. “Conservation of two distinct types of 100S ribosome in bacteria.” Genes Cells, 18, 554-574 (2013), doi: 10.1111/gtc.12057.

・Ohniwa RL, Kitabayashi K and Morikawa K. Alternative cardiolipin synthase Cls1 compensates for stalled Cls2 function in Staphylococcus aureus under conditions of acute acid stress. FEMS Microbiol Lett, 338, 141-6, 2013, doi: 10.1111/1574-6968.12037. Epub 2012 Nov 22.

・Ohniwa RL, Ushijima Y, Saito S and Morikawa K, “Proteomic Analyses of Nucleoid-Associated Proteins in Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus.” PLoS ONE, 6(4), e19172 (2011)

・Tsai M*, Ohniwa RL*, Kato Y, Takeshita SL, Ohta T, Saito S, Hayashi H and Morikawa K. “Staphylococcus aureus requires cardiolipin for survival under high salinity conditions.”(*equal contribution) BMC Microbiology, 11:13 (2011)

・Maruyama H, Shin M, Oda T, Matsumi R, Ohniwa RL, Itoh T, Shirahige K, Imanaka T, Atomi H, Yoshimura SH and TakeyasuK. “Histone and TK0471/TrmBL2 form a novel heterogeneous genome architecture in the hyperthermophilic archaeon Thermococcus kodakarensis.” Mol Biol Cell, 22, 386-98 (2011)

・Oda T, Ohniwa RL, Suzuki Y, Denawa M, Kumeta M, Okamura H and TakeyasuK., “Evolutionary dynamics of spliceosomal intron revealed by in silico analyses of the P-Type ATPase superfamily genes.” Mol Biol Rep, 38(4), 2285-2293 (2011)

・ Morikawa K, Ohniwa RL, Ohta T, Tanaka Y, Takeyasu K and Msadek T. “Adaptation beyond the Stress Response: Cell Structure Dynamics and Population Heterogeneity in Staphylococcus aureus.” Microbes Environ, 25(2),75-82 (2010)

  ・Ohniwa RL, Morikawa K, Wada C, Ohta T and Takeyasu T. “Nucleoid Architecture and Dynamics in bacteria.” Bacterial DNA, DNA Polymerase and DNA Helicases, Nova Science Publishers, Inc. Chapter 3, 91-117 (2010)

・Niwa R, Hada K, Moliyama K, Ohniwa RL, Tan Y, Cather KO, Chi W, Reinke W and Slack FJ, ”C. elegans sym-1 is a downstream target of the Hunchback-like-1 developmental timing transcription factor.” Cell Cycle, 15;8(24), 4147-54 (2009)

・Morikawa K, Ohniwa RL, Kumano M, Okamura H, Saito S and Ohta T, “The sigH gene sequence can subspeciate staphylococci.” Diagnostic Microbiology and Infectious Disease, 61, 373-380 (2008)

・Ueta M, Ohniwa RL, Yoshida H, Maki Y, Wada C and Wada A. “Role of HPF (Hibernation promoting factor) on translational activity in Escherichia coli.” J Biochem, 143, 425-433 (2008)

・Shindo E, Kubo K, Ohniwa RL, Takeyasu K and Yoshikawa K. “In situ analysis of the higher-order genome structure in a single Escherichia coli cell.” J Biotech, 133, 172-176 (2008)

・Ohniwa RL, Morikawa K, Takeshita SL, Kim J, Ohta T, Wada C and Takeyasu K “Transcription-coupled Nucleoid Architecture in Bacteria.” Genes Cells, 12, 1141-52 (2007)

・Kobori T, Hizume K, Ohniwa RL, Yoshimura SH and Takeyasu K. “Biochemical and Biophysical Basis of Genome Folding Mechanisms.” Progress in Biopolymer Research, 107-135 (2007)

・Ohniwa RL, Morikawa K, Kim J, Kobori T, Hizume K, Matsumi R, Atomi H, Imanaka T, Ohta T, Yoshimura SH, Wada C, and Takeyasu K. “Atomic Force Microscopy Dissects the Hierarchy of Genome Architectures in Eukaryote, Prokaryote and Chloroplast.” Microscopy & Microanalysis, 13, 3-12 (2007)

・Morikawa K, Ohniwa RL, Kim J, Takeshita SL, Maruyama A, Inose Y, Takeyasu K and Ohta T. “Biochemical, Molecular Genetic, and Structural Analyses of the Staphylococcal Nucleoid.” Microscopy & Microanalysis, 13, 30-35 (2007)

・Ohniwa RL, Morikawa K, Kim J, Ohta T, Ishihama A, Wada C and Takeyasu K. “Dynamic state of DNA topology is essential for genome condensation in bacteria.” EMBO J, 25, 5591-5602 (2006)

・Hirano Y, Ohniwa RL, Wada C, Yoshimura SH and Takeyasu K. “Human small G proteins, ObgH1 and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures.” Genes Cells, 11, 409-423 (2006)

・Morikawa K, Ohniwa RL, Kim J, Maruyama A, Ohta T and Takeyasu K. “Bacterial nucleoid dynamics: oxidative stress response in Staphylococcus aureus.” Genes Cells, 11, 409-423 (2006)

  ・Takeyasu K, Hizume K, Kobori T, Kodama M, Ohniwa RL and Yoshimura SH. “AFM elucidates genome architectures where reconstitution of chromatin fibers and dissection of nuclear chromatin meet.” Proceedings of the VII. Linz Winter Workshop, 111-116 (2006)

  ・大庭良介 竹安邦夫 (2006)膜融合の立役者:SNAREタンパク質 生体の科学 57巻 2号 83-90.

  ・岡村英幸 大庭良介 竹安邦夫 (2006)P型ATPaseの分子進化 生体の科学 57 巻 5号 413-415

  ・大庭良介 竹安邦夫 (2006)SNAREの分子進化 生体の科学 57 巻 5号 456-457

  ・Sato MH, Ohniwa RL and Uemura T.(2005)“SNAREs in plant endocytosis and the post-Golgi traffic.” The Plant endocytosis (chapter 13)

・Takeyasu K, Kim J, Ohniwa RL, Kobori T, Inose Y, Morikawa K, Ohta T, Ishihama A and Yoshimura SH. “Genome architecture studied by nanoscale imaging: analyses among bacterial phyla and their implication to eukaryotic genome folding.” Cytogenet Genome Res, 107, 38-48 (2004)

・Kim J, Yoshimura SH, Hizume K, Ohniwa RL, Ishihama A and Takeyasu K. “Fundamental structural units of the Escherichia coli nucleoid revealed by atomic force microscopy.” Nucleic Acids Res, 32, 1982-1992 (2004)

・Uemura T, Ueda T, Ohniwa RL, Nakano A, Takeyasu K and Sato MH. “Systematic analysis of SNARE molecules in Arabidopsis: dissection of the post-Golgi network in plant cells.” Cell Struct Funct, 29, 49-65 (2004)

・Okamura H, Denawa M, Ohniwa RL, Takeyasu K. “P-type ATPase superfamily: evidence for critical roles for kingdom evolution.” Ann N Y Acad Sci, 986, 219-23 (2003)

・Yoshimura SH, Ohniwa RL, Sato MH, Matsunaga F, Kobayashi G, Uga H, Wada C and Takeyasu K. “DNA phase transition promoted by replication initiator.” Biochemistry, 39, 9139-9145 (2000)

  ・Yoshimura SH, Ohniwa LS, Ogita Y and Takeyasu K. “The sodium pump goes to the nucleus: when, how and why?” Na/K-ATPase and Related ATPase, 625-632



 6.Solution from academic diplomat

・大庭良介 International Medical Science Course (台湾での伝統中国医学コースへの17日間の派遣) Tsukuba Journal of Medical Science. 14(2) (2018)

・大庭良介 須田恭介 入江賢児 International Medical Science Course (2015年度国立台湾大学への10日間の派遣) Tsukuba Journal of Medical Science. 12(2): 3-22. (2016)

・大庭良介 International Medical Science Course (国立台湾大学への8日間の派遣) Tsukuba Journal of Medical Science. 11(1): 26-37. (2015)

   ・Ohniwa RL,“ University of Tsukuba Oversea Offices”, Cross-Strait Conference for Senior Administrators 2015 (2015年6月台北)

   ・Ohniwa RL, “The activities of UT in Taiwan; Past, Present and Future”, NTU International Affair Workshop(2017年7月台北)

   ・Ohniwa RL, “Short Programs in UT”, International Administrator's Workshop 2017 (2017年12月台北)








Copyright (C) Ryosuke Ohniwa, University of Tsukuba, All Rights Reserved.