Mice share 95% of human genes and develop many of the same human diseases
caused by the same genetic factors. Therefore, the laboratory mouse is
a very useful experimental animal that provides us with an essential experimental
platform for the advancement of medical research. In particular, genetically
engineered mice are very commonly used to investigate the function of genes
and proteins involved in development, homeostasis, and disease.
Our Lab aim to develop a new concept of genetically engineered animals that will serve as the basis for future medical and life science research by combining advanced manipulation techniques of mouse early embryos and mouse ES cells with the latest genome editing technology.
We also aim to elucidate unknown biological phenomena in the heart and germ cells by using these mouse models.
For more information, please see the video of Mizuno's public mini-lecture on the production of genetically modified mice using genome editing technology.
Last update Jan. 9th, 2024