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研究紹介
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| 「cDNAの核内直接注入によるBDNF動態の可視化」
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(Kohara, K., Kitamura, A., Morishima, M. and
Tsumoto, T.Activity-dependent transfer of brain-derived neurotrophic
factor to postsynaptic neurons. Science, 291, 2419-2423, 2001) |
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| 「アルツハイマー病アミロイドβペプチド（Aβ）を分解するシステムの同定」 |
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(Iwata, N., Tsubuki, S., Takaki, Y., Shirotani,
K., Lu, B., Gerard,N.P., Gerard, C., Hama, E., Lee, H.-J., Saido,
T.C.Metabolic regulation of brain Aβ by neprilysin. Science, 292,1550-1552,
2001) |
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| 「CRMP-2は海馬神経細胞の軸索形成を誘導する」 |
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(Inagaki N., Chihara, K., Arimura,
N., Menager, C., Kawano, Y., Matsuo,N., Nishimura, T., Amano, M.
and Kaibuchi,K. CRMP-2 induces axons incultured hippocampal neurons.
Nature Neurosci. 4, 781-782, 2001) |
| |
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| 「常染色体劣性遺伝性パーキンソン病の病因遺伝子、パーキンの基質の同定 |
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(Imai, Y., Soda, M., Inoue, H.,
Hattori, N., Mizuno, Y. and Takahashi,R. An unfolded putative transmembrane
polypepyide, which can lead to endoplasmic reticulum stress, is
a substrate of Parkin. Cell, 105,891-902, 2001) |
| |
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| 「眼球運動失行と低アルブミン血症を伴う早発型失調性（EAOH）の疾患遺伝子の同定」 |
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(Date, H., Onodera, O., Tanaka,
H., Iwabuchi, K., Uekawa, K., Igarashi, S., Koike, R., Hiroi, T.,
Yuasa, T., Awaya, Y., Sakai, T., Takahashi, T., Nagatomo, H., Sekijima,
Y., Kawachi, I., Takiyama, Y., Nishizawa, M., Fukuhara, N., Saito,
K., Sugano, S., and Tsuji, S. Early-onset ataxia with ocular motor
apraxia and hypoalbuminemia is caused by mutations in a novel HIT
superfamily protein, aprataxin. Nat. Genet. 29, 184-188 2001) |
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| 「運動前野の細胞活動は動作企画に必要な情報の統合を行う」 |
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(Hoshi, E. and Tanji, J. Integration
of target and body-part information in the premotor cortex when
planning action. Nature, 466-470, 2000) |
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| 「感覚系視床における報酬予測に対する後ろ向きおよび前向き符号化」 |
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(Komura, Y., Tamura, R., Uwano,
T., Nishijo, H., Kaga, K., and Ono, T. Retrospective and prospective
coding for predicted reward in the sensory thalamus. Nature 412,
546-549, 2001) |
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