Soft Matrix Promotes Cardiac Reprogramming via Inhibition of YAP/TAZ and Suppression of Fibroblast Signatures
Highlights
• ECM comparable with native myocardium promotes cardiac reprogramming.
• Soft ECM promotes cardiac reprogramming via YAP/TAZ/fibroblast signaling inhibition.
• Soft ECM promotes Sendai virus vector-mediated cardiac reprogramming.
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