Chemically defined cytokine-free expansion of human haematopoietic stem cells
Researchers from the University of Tsukuba develop a system for effectively growing large numbers of blood stem cells outside of the human body
Tsukuba, Japan—Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type. HSC transplants can be used to treat conditions where bone marrow is damaged and no longer able to produce healthy blood cells, but the widespread and safe use of HSCs is limited by barriers to cell growth and expansion in the lab (i.e. ex vivo). Now, a team led by researchers at the University of Tsukuba has established a novel culture system that supports long term ex vivo expansion of HSCs…
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Nature 【DOI】 10.1038/s41586-023-05739-9
Chemically defined cytokine-free expansion of human haematopoietic stem cells.
→ Research Outline (PDF In Japanese language)