桝　正幸　（筑波大学・基礎医学系）

1.Tominaga M, Wada M, Masu M: Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia. Proc Natl Acad Sci USA 98: 6951-6956, 2001

2.Ohto T, Uchida H, Yamazaki H, Keino-Masu K, Matsui A, Masu M: Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage. Genes Cells 7: 173-186, 2002

3.Tsukada S, Keino-Masu K, Masu M, Fukuda J: Activation of protein kinase A by nitric oxide in cultured dorsal root ganglion neurites of the rat, examined by a fluorescence probe, ARII. Neurosci Lett 318: 17-20, 2002

岡野栄之　（慶應義塾大学・医学部）

1.Toda M, Iizuka Y, Yu W-J, Ikeda E, Yoshida K, Imai T, Kawase T, Kawakami Y, Okano H, Uyemura K: Expression of the neural RNA-binding protein Musashi1 in human gliomas. Glia 34: 1-7, 2001

2.Mori H, Sakakibara S, Imai T, Nakamura Y, Iijima T, Suzuki A, Yuasa Y, Takeda M, Okano H: Expression of mouse igf2 mRNA-binding protein 3 and its implication in the developing central nervous system. J Neurosci Res 64: 132-143, 2001

3.Murata T, Nagaso H, Watanabe S, Okano H, Yokoyama K: The hiiragi gene encodes a poly(A) polymerase, which controls the formation of the wing margin in Drosophila melanogaster. Dev Biol 233: 137-147, 2001

4.Okabe M, Imai T, Kurusu M, Hiromi Y, Okano H: Translational repression determines a neuronal potential in Drosophila asymmetric cell division. Nature 411: 94-98, 2001

5.Sawamoto K, Yamamoto A, Kawaguchi A, Yamaguchi M, Mori K, Goldman SA, Okano, H: Visualization and direct isolation of neuronal progenitor cells by dual-color flow cytometric detection of fluorescent proteins. J Neurosci Res 65: 220-227, 2001

6.Sawamoto K, Nakao N, Kakishita K, Ogawa Y, Toyama Y, Yamamoto A, Yamaguchi M, Mori K, Goldman SA, Itakura T, Okano H: Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci 21: 3895-3903, 2001

7.Imai T, Tokunaga A, Yoshida T, Hashimoto M, Weinmaster G, Mikoshiba K, Nakafuku M, Okano H: The neural RNA-binding protein Musashi1 translationally regulaties the m-numb gene expression by interacting with its mRNA. Mol Cell Biol 21: 3888-3900, 2001

8.Sawamoto K, Nakao N, Kobayashi K, Matsushita N, Takahashi H, Kakishita K, Yamamoto A, Yoshizaki T, Terashima T, Murakami F, Itakura T, Okano, H: Visualization and direct isolation of midbrain dopaminergic neurons expressing GFP. Proc Natl Acad Sci USA 98: 6423-6428, 2001

9.Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K: Genetic and functional analysis of PARP, a DNA strand break-binding enzyme. Mutat Res 47: 89-96, 2001

10.Ishida Y, Nakamoto H, Imai H, Suzuki S, Okano H, Suzuki H: Heme oxygenase-1 regulates vascular tone of the peritoneum undergoing peritoneal dialysis. Adv Perit Dial 17: 15-19, 2001

11.Li R-Y, Baba S, Kosugi I, Arai Y, Kawasaki H, Shinmura Y, Sakakibara S, Okano H, Tsusui Y: Activation of murine cytomegalovirus immediate-early promoter in cerebral ventricular zone and glial progenitor cells in transgenic mice. Glia 35: 41-52, 2001

12.Yagita Y, Kitagawa K, Otsuki T, Kuwabara K, Mabuchi T, Miyata T, Okano H, Hori M, Matsumoto, M: Proliferation of neuronal progenitor cells and increased neurogenesis in the ischemic adult rat hippocampus. Stroke 32: 1890-1896, 2001

13.Miyata T, Kawaguchi A, Okano H, Ogawa M: Asymmetric inheritance of radial glial fibers to neurons during corticogensis in mice. Neuron 31: 727-741, 2001

14.Kohyama J, Abe H, Shimazaki T, Koizumi A, Nakashima K, Taga T, Okano H, Hata J, Umezawa A: Brain from Bone: Efficient "meta-differentiation" of marrow stromal-derived mature osteoblasts to neurons with Noggin or a demethylating agant. Differentiation 68: 235-244, 2001

15.Keyoung HM, Roy NS, Benraiss A, Louissaint A Jr, Suzuki A, Hashimoto K, Rashbaum WK, Okano H, Goldman SA: Prospective identification, selection and extraction of two distinct pools of neural stem cells from fetal human brain. Nat Biotech 19: 843-850, 2001

16.Kanemura Y, Mori K, Sakakibara S, Ohnishi T, Fujikawa H, Hayashi H, Matsumoto T, Imai T, Ohnishi T, Fushiki S, Nakamura Y, Yamasaki M, Okano H, Arita N: Musashi1, an evolutionarily conserved neural RNA-binding protein is a versatile marker of human glioma cells in determining their cellluar origin, malignancy and proliferative activity. Differentiation 68: 141-152, 2001

17.Sakakibara S, Nakamura Y, Satoh H, Okano H: RNA-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulation of neurons in mammalian CNS. J Neurosci 21: 8097-8107, 2001

18.Yamamoto N, Matsunaga E, Yamamoto S, Kobayashi D, Torii M, Kawaichi M, Kishi N, Matsuno K, Okano H, Nakafuku M: Deltex as a nuclear signal transducer downstream of the Notch receptor. J Biol Chem 276: 45031-45940, 2001

19.Saunders PTK, Maguire SM, Macpherson S, Fenelon MC, Sakakibara S, Okano H: The RNA binding protein Musashi1 (Msi1) is expressed in the cytoplasm and nucleus of Sertoli cells in the rat testis from fetal life to adulthood. Biol Reprod 66: 500-507, 2002

20.Uchida M, Hanai S, Uematsu N, Sawamoto K, Okano H, Miwa M, Uchida K: Overexpression of poly(ADP-ribose) polymerase disrupts organization of cytoskeletal F-actin and tissue polarity in Drosophila. J Biol Chem 277: 6696-6702, 2002

21.Matsuno K, Ito M, Hori K, Miyashita F, Suzuki S, Kishi N, Artravanis-Tsakonas S, Okano H: Involvement of a proline-rich motif and a RING-H2 finger in a function of Deltex as a regulator of Notch signaling. Development 129: 1049-1059, 2002

22.Iwai Y, Hirota Y, Ozaki K, Okano H, Takeichi M, Uemura T: DN-cadherin-dependent synaptogenesis in the Drosophila visual system. Mol Cell Neurosci in press

23.Takasawa K-I, Kitagawa K, Yagita Y, Sasaki T, Tanaka S, Ohtsuki T, Miyata T, Okano H, Hori M, Matsumoto M: Increased proliferation of neural progenitor cells but reduced survival newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats. J Cereb Blood Flow Metab in press

24.Shibata M, Yamawaki T, Fukuuchi Y, Okano H, Miura M: Up-regulation of Akt phosphorylation contributes to improved cell viability in the ischemic penumbra at the early stage of middle cerebral artery occlusion in mice. Brain Res in press

中福雅人　（東京大学・大学院医学系研究科）

1.Mizuguchi R, Sugimori M, Takebayashi H, Kosako H, Nagao M, Yoshida S, Nabeshima Y, Shimamura K, Nakafuku M: Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons. Neuron 31: 757-771, 2001

2.Yamamoto S, Nagao M, Sugimori M, Kosako H, Nakatomi H, Yamamoto N, Takebayashi H, Nabeshima Y, Kitamura T, Weinmaster G, Nakamura K, Nakafuku M: Transcription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord. J Neurosci 21: 9814-9823, 2001

3.Yamamoto S, Yamamoto N, Kitamura T, Nakamura K, Nakafuku M: Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp Neurol 172: 115-127, 2001

4.Yamamoto N, Yamamoto S, Inagaki F, Kawaichi M, Fukamizu A, Kishi N, Matsuno K, Nakamura K, Weinmaster G, Okano H, Nakafuku M: Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J Biol Chem 276: 45031-45040, 2001

5.Kobayashi D, Kobayashi M, Ogura T, Nakafuku M, Shimamura K: Early subdivisions in the neural plate define distinct competence for inductive signals. Development 129: 83-93, 2002　

6.Kato M, Seki N, Sugano S, Hashimoto K, Masuho Y, Muramatsu M, Kaibuchi K, Nakafuku M: Identification of sonic hedgehog-responsive genes by using cDNA microarray. Biochem Biophy Res Commun 289: 472-478, 2001

7.Imai1T, Tokunaga A, Yoshida T, Hashimoto M, Mikoshiba K, Weinmaster G, Nakafuku M, Okano H: The neural RNA-binding protein Musashi1 translationally regulates the m-numb gene expression by interacting with its mRNA. Mol Cell Biol 21: 3888-3900, 2001

8.Nakashima K, Takizawa T, Ochiai W, Yanagisawa M, Hisatsune T, Nakafuku M, Miyazono K, Kishimoto T, Kageyama R, Taga T: BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci USA 98: 5868-5873, 2001

9.Fu H, Qi Y, Tan M, Cai J, Takebayashi H, Nakafuku M, Richardson W, Qiu M: Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development 129: 681-693, 2002　

10.Kamimori K, Machide M, Tomita K, Nakafuku M, Kohsaka S: Cell-type specific expression of protein tyrosine kinase-related receptor RYK in the central nervous system of the rat. Mol Brain Res in press

11.Heins N, Malatesta P, Cecconi F, Nakafuku M, Tucker K L, Hack M A, Chapouton P, Barde Y-A, Götz M: Glial cells generate neurons: The role of the transcription factor Pax6. Nat Neurosci in press

五十嵐道弘　（新潟大学・大学院医歯学総合研究科）

1.Ohyama A, Hosaka K, Komiya Y, Akagawa K, Yamauchi E, Taniguchi H, Sasakawa N, Kumakura K, Mochida S, Yamauchi T, Igarashi M: Regulation of exocytosis through Ca²⁺/ATP-dependent binding of autophosphorylated CaMKII to syntaxin 1A. J Neurosci in press

2.Nagashima K, Torii S, Yi Z, Igarashi M, Okamoto K, Takeuchi T, Izumi T: Melanophilin/exophilin 3 directly links rab27a and myosin Va through its distinct coiled-coil regions. FEBS Lett in press

石川良樹　（群馬大学・医学部）

1.Samizo K, Ishikawa R, Nakamura A, Kohama K: A highly sensitive method for measurement of myosin ATPase activity by reversed-phase high performance liquid chromatography.　 Anal Biochem 293: 212-215, 2001

井上芳郎　 （北海道大学・大学院医学研究科）

1.Nakamura K, Manabe T, Watanabe M, Mamiya T, Sanbo M, Ichikawa R, Kiyama Y, Inoue Y, Nabeshima T, Yagi T, Mori H, Mishina M: Enhancement of hippocampal LTP reference memory and sensorymotor gating in mutant mice lacking a telencephalon-specific cell adhesion molecule. Eur J Neurosci 13: 179-189, 2001

2.Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K, Mishina M, Hashikawa T, Konnerth A, Watanabe M, Kano M: Roles of GluRδ2 and mGluR1 in climbing fiber synapse elimination during postnatal cerebellar development. J Neurosci 21: 9701-9712, 2001

小椋利彦　（奈良先端科学技術大学院大学・バイオサイエンス研究科）

1.Ogura K, Matsumoto K, Kuroiwa A, Isobe T, Otoguro T, Jurecic V, Baldini A, Matsuda Y, Ogura T: Cloning and chromosomal mapping of human and chicken iroquois (Irx) genes. Cytogenet Cell Genet 92: 320-325, 2001

2.Kobayashi D, Kobayashi M, Matsumoto K, Ogura T, Nakafuku M, Shimamura K: Early subdivisions in the neural plate define distinct competence for inductive signals. Development 129: 83-93, 2002

貝淵弘三　（名古屋大学・大学院医学研究科）

1.Nakagawa M, Fukata M, Yamaga M, Itoh N, Kaibuchi K: Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites. J Cell Sci 114: 1829-1838, 2001

2.Mukai Y, Shimokawa H, Matoba T, Kandabashi T, Satoh S, Hiroki J, Kaibuchi K, Takeshita A: Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension. FASEB J 15: 1062-1064, 2001

3.Morishige K, Shimokawa H, Eto Y, Kandabashi T, Miyata K, Matsumoto Y, Hoshijima M, Kaibuchi K, Takeshita A: Adenovirus-mediated transfer of dominant-negative rho-kinase induces a regression of coronary arteriosclerosis in pigs in vivo. Arterioscler Thromb Vasc Biol 21: 548-554, 2001

4.Katoh K, Kano Y, Amano M, Kaibuchi K, Fujiwara K: Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts. Am J Physiol Cell Physiol 280: C1669-1679, 2001

5.Katoh K, Kano Y, Amano M, Onishi H, Kaibuchi K, Fujiwara K: Rho-kinase-mediated contraction of isolated stress fibers. J Cell Biol 153: 569-584, 2001

6.Shah V, Bharadwaj S, Kaibuchi K, Prasad GL: Cytoskeletal organization in tropomyosin-mediated reversion of ras-transformation: Evidence for Rho kinase pathway. Oncogene 20: 2112-2121, 2001

7.Shimokawa H, Morishige K, Miyata K, Kandabashi T, Eto Y, Ikegaki I, Asano T, Kaibuchi K, Takeshita A: Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo. Cardiovasc Res 51: 169-177, 2001

8.Funakoshi Y, Ichiki T, Shimokawa H, Egashira K, Takeda K, Kaibuchi K, Takeya M, Yoshimura T, Takeshita A: Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells. Hypertension 38: 100-104, 2001

9.Zong H, Kaibuchi K, Quilliam LA: The insert region of RhoA is essential for Rho kinase activation and cellular transformation. Mol Cell Biol 21: 5287-5298, 2001

10.Inagaki N, Chihara K, Arimura N, Menager C, Kawano Y, Matsuo N, Nishimura T, Amano M, Kaibuchi K: CRMP-2 induces axons in cultured hippocampal neurons. Nat Neurosci 4: 781-782, 2001

11.Szaszi K, Kurashima K, Kaibuchi K, Grinstein S, Orlowski J: Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na⁺/H⁺ exchanger NHE3. J Biol Chem 276: 40761-40768, 2001

12.Ohnaka K, Shimoda S, Nawata H, Shimokawa H, Kaibuchi K, Iwamoto Y, Takayanagi R: Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts. Biochem Biophys Res Commun 287: 337-342, 2001

13.Kato M, Seki N, Sugano S, Hashimoto K, Masuho Y, Muramatsu M, Kaibuchi K, Nakafuku M: Identification of sonic hedgehog-responsive genes using cDNA microarray. Biochem Biophys Res Commun 289: 472-478, 2001

14.Taya S, Inagaki N, Sengiku H, Makino H, Iwamatsu A, Urakawa I, Nagao K, Kataoka S, Kaibuchi K: Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF. J Cell Biol 155: 809-820, 2001

15.Delon J, Kaibuchi K, Germain RN: Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity 15: 691-701, 2001

16.Pantaleon M, Kanai-Azuma M, Mattick JS, Kaibuchi K, Kaye PL, Wood SA: FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development. Mech Dev 109: 151-160, 2001

17.Kandabashi T, Shimokawa H, Mukai Y, Matoba T, Kunihiro I, Morikawa K, Ito M, Takahashi S, Kaibuchi K, Takeshita A: Involvement of rho-kinase in agonists-induced contractions of arteriosclerotic human arteries. Arterioscler Thromb Vasc Biol 22: 243-248, 2002

18.Soto MC, Qadota H, Kasuya K, Inoue M, Tsuboi D, Mello CC, Kaibuchi K: The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans. Genes Dev in press

鹿川哲史　（岡崎国立共同研究機構・生理学研究所）

1.Ono K, Kagawa T, Tsumori T, Yokota S, Yasui Y: Morphological changes and cellular dynamics of oligodendrocyte lineage cells in the developing vertebrate central nervous system. Dev Neurosci 23: 346-355, 2001

2.Yamada M, Yung M, kagawa T, Ivanova A, Nave K, Ikenaka K: Mutant Plp/DM20 cannot be processed to secrete PLP-related oligodendrocyte differentiation/survival factor. Neurochem Res 26: 639-645, 2001

見学美根子　（京都大学・大学院理学研究科）

1.Yamasaki T, Kawaji K, Ono K, Bito H, Hirano T, Osumi N, Kengaku M: Pax6 regulates granule cell polarization during parallel fiber formation in the developing cerebellum.　 Development 128: 3133-3144, 2001

斎藤哲一郎　（京都大学・再生医科学研究所）

1.Tamura T, Kanno Y, Chuma S, Saito T, Nakatsuji N: Pod-1/Capusulin shows a sex- and stage-dependent expression pattern in the mouse gonad development and represses expression of Ad4BP/SF-1. Mech Dev 102: 135-144, 2001

2.Saito T, Nakatsuji N: Efficient gene transfer into the embryonic mouse brain using in vivo electroporation. Dev Biol 240: 237-246, 2001

佐藤　真　（福井医科大学・医学部）

1.Tanaka M, Miyoshi J, Ishizaki H, Togawa A, Endo K, Matsubara K, Mizoguchi A, Nagano T, Sato M, Sasaki T, Takai Y: Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. Mol Biol Cell 12: 421-1430, 2001

2.Takamura Y, Yagi H, Hase K, Yoneda T, Maeda M, Akagi Y, Sato M: JDD1, a novel member of Dna J family, expressed in the germinal zone of the rat brain. Biochem Biophys Res Commun 285: 387-392, 2001

3.Suzuki F, Taniguchi T, Nakamura S, Akagi Y, Kubota C, Sato M, Muramatsu M: Distribution of alpha-1 adrenoceptor subtypes in RNA and protein in rabbit eyes. Br J Pharmacol 135: 600-608, 2002

4.Takamura Y, Kubo E, Tsuzuki S, Yagi H, Sato M, Akagi Y: Increased expression of p21WAF1/CIP1 in the lens epithelium of rat sugar cataract. Exp Eye Res in press

新谷隆史　（岡崎国立共同研究機構・基礎生物学研究所）

1.Shintani T, Maeda N, Noda M: Receptor-like protein tyrosine phosphatase (RPTPγ), but not PTPζ/RPTPβ, inhibits nerve-growth-factor-induced neurite outgrowth in PC12D cells. Dev Neurosci 23: 55-69, 2001

2.Sakuta H, Suzuki R, Takahashi H, Kato A, Shintani T, Iemura SH, Yamamoto TS, Ueno N, Noda M: Ventroptin: a BMP-4 antagonist expressed in a double-gradient pattern in the retina. Science 293: 111-115, 2001

須田容子　（理化学研究所・発生再生科学研究センター）

1.Suda S, Hossain ZM, Kobayashi C, Hatano O, Yoshida M, Matsuo I, Aizawa S: Emx2 directs the development of diencephalon in cooperation with Otx2. Development 128: 2433-2450, 2001

高橋政代　（京都大学・大学院医学研究科）

1.Kurimoto Y, Shibuki H, Kaneko Y, Ichikawa M, Kurokawa T, Takahashi M, Yoshimura N: Transplantation of adult rat hippocampus-derived neural stem cells into retina injured by transient ischemia. Neurosci Lett 306: 57-60, 2001

2.Inatani M, Haruta M, Honjo M, Oohira A, Kido N, Takahashi M, Honda Y, Tanihara H: Upregulated expression of N-syndecan, a transmembrane heparan sulfate proteoglycan, in differentiated neural stem cells. Brain Res 920: 217-221, 2001

3.Haruta M, Kosaka M, Kanegae Y, Saito I, Inoue T, Kageyama R, Nishida A, Honda Y, Takahashi M: Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue. Nat Neurosci 4: 1163-1164, 2001

4.Kawasaki H, Suemori H, Mizuseki K, Watanabe K, Urano F, Ichinose H, Haruta M, Takahashi M, Yoshikawa K, Nishikawa SI, Nakatsuji N, Sasai Y: Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc Natl Acad Sci USA 99: 1580-1585, 2002

田中光一　（東京医科歯科大学・難治疾患研究所）

1.Katagiri H, Tanaka K, Manabe T: Requirement of appropriate glutamate concentrations in the synaptic cleft for hippocampal LTP induction. Eur J Neurosci 14: 547-553, 2001

2.Sugiyama T, Sadzuka Y, Tanaka K, Sonobe T: Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin. Toxicol Lett 121: 89-96, 2001

3.Gray C, Marie H, Arora M, Tanaka K, Boyde A, Jones S, Attwell D: Glutamate does not play a major role in controlling bone growth. J Bone Miner Res 16: 742-749, 2001

4.Nishizaki T, Nagai K, Nomura T, Tada H, Kanno T, Tozaki T, Li X, Kondoh T, Kodama N, Takahashi E, Sakai N, Tanaka K, Saito N: A new neuromodulator pathway with a glial contribution mediated via A_2a adrenergic receptors. Glia in press

谷口雅彦　（東京大学・大学院医学系研究科）

1.Kawasaki T, Bekku Y, Suto F, Kitsukawa T, Taniguchi M, Nagatsu I, Nagatsu T, Itoh K, Yagi T, Fujisawa H: Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system. Development 129: 671-680, 2002  

2.Sugimoto Y, Taniguchi M, Yagi T, Akagi Y, Nojyo Y, Tamamaki N: Guidance of glial precursor cell migration by secreted cues in the developing optic nerve. Development 128: 3321-3330, 2001

坪井昭夫　（東京大学・大学院理学系研究科）

1.Ishii T, Serizawa S, Kohda A, Nakatani H, Shiroishi T, Okumura K, Iwakura Y, Nagawa F, Tsuboi A, Sakano H: Monoallelic expression of the odorant receptor gene and axonal projection of olfactory sensory neurones. Genes Cells 6: 71-78, 2001

2.Sengoku S, Ishii T, Serizawa S, Nakatani H, Nagawa F, Tsuboi A, Sakano H: Axonal projection of olfactory sensory neurons during the developmental and regeneration processes. NeuroReport 12: 1061-1066, 2001

仲嶋一範　（東京慈恵会医科大学・DNA医学研究所）

1.Tabata H, Nakajima K: Efficient in utero gene transfer system to the developing mouse brains using electroporation: Visualization of neuronal migration in the developing cortex. Neuroscience 103: 865-872, 2001

中島欽一　（熊本大学・発生医学研究センター）

1.Takizawa T, Nakashima K, Namihira M, Ochiai W, Uemura A, Yanagisawa M, Fujita N, Nakao M, Taga T: DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev Cell 1: 749-758, 2001

2.Koyama J, Abe H, Shimazaki T, Koizumi A, Nakashima K, Gojo S, Taga T, Okano H, Hata J, Umezawa A: Brain from bone: Efficient"meta-differentiation"of marrow stroma-derived mature osteoblast to neurons with noggin or a demethylating agent. Differentiation 68: 235-244, 2001

3.Setoguchi T, Yone K, Matsuoka E, Takenouchi N, Nakashima K, Sakou T, Komiya S, Izumo S: Traumatic injury-induced BMP7 expression in the adult rat spinal cord. Brain Res 921: 219-225, 2001

4.Yanagisawa M, Nakashima K, Takeda K, Ochiai W, Takizawa T, Ueno M, Takizawa M, Shibuya H, Taga T: Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7. Genes Cells 6: 1091-1099, 2001

5.Yanagisawa M, Takizawa T, Ochiai W, Uemura A, Nakashima K, Taga T: Fate alteration of neuroepithelial cells from neurogenesis to astrocytogenesis by bone morphogenetic proteins. Neurosci Res 41: 391-396, 2001

6.Choi M, Yamamoto K, Masuno H, Nakashima K, Taga T, Yamada S: Ligand recognition by the vitamin D receptor. Bioorg Med Chem 9: 1721-1730, 2001

7.Matsuo R, Ochiai W, Nakashima K, Taga T: A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody. J Immunol Meth 247: 141-151, 2001

8.Nakashima K, Takizawa T, Ochiai W, Yanagisawa M, Hisatsune T, Nakafuku M, Miyazono K, Kishimoto T, Kageyama R, Taga T: BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci USA 98: 5868-5873, 2001

9.Takizawa T, Yanagisawa M, Ochiai W, Yasukawa K, Ishiguro T, Nakashima K, Taga T: Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of stat3. Cytokine 13: 272-279, 2001

10.Ochiai W, Yanagisawa M, Takizawa T, Nakashima K, Taga T: Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of stat3. Cytokine 14: 264-271, 2001

11.Yanagisawa M, Nakashima K, Takizawa T, Ochiai W, Arakawa H, Taga T: Signaling crosstalk underlying synergistic induction of astrocyte differentiation by BMPs and IL-6 family of cytokines. FEBS Lett 489: 139-143, 2001

12.Nakashima K, Taga T: Mechanism underlying cytokine-mediated cell fate regulation in the nervous system. Mol Neurobiol in press

13.Uemura A, Takizawa T, Ochiai W, Yanagisawa Y, Nakashima K, Taga T: Cardiotrophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of STAT3. Cytokine in press

14.Kimura K, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Nobuhisa I, Taga T: Identification of a novel transcription factor, ELYS, expressed predominantly in mouse fetal hematopoietic tissues. Genes Cells in press

中山耕造　（信州大学・医学部）

1.Kawa S, Nikaido T, Unno H, Usuda N, Nakayama K, Kiyosawa K: Growth inhibition and differentiation of pancreatic cancer cell lines by PPARγ ligand troglitazone through the up-expression of WAF1/CIP1/p21. Pancreas 24: 1-7, 2002

2.Sugane K, Takamoto M, Nakayama K, Tada T, Yuasa T, Kurokawa K: Diagnosis of Toxoplasma meningoencephalitis in a non-AIDS patient using PCR. J Infect 42: 159-160, 2001

3.Li W, Okano A, Tiana Q, Nakayama K, Furihata T, Nawa H, Suzuki T: Characterization of a novel synGAP isoform, synGAP-beta. J Biol Chem 276: 21417-21424, 2001

4.Hamano H, Kawa S, Horiuchi A, Unno H, Furuya N, Akamatsu T, Fukushima M, Nikaidou T, Nakayama K, Kiyosawa K: High serum IgG4 concentrations in patients with sclerosing pancreatitis. New Eng J Med 344: 732-738, 2001

5.Masumoto J, Taniguchi S, Nakayama K, Ayukawa K, Sagara J: Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos. Exp Cell Res 262: 128-133, 2001

6.Ebara S, Nakayama K: The regulatory mechanism of BMP expression and its signal transduction. Spine in press

7.Ohta K, Nakayama K, Kurokawa T, Kikuchi T, Yoshimura N: Inhibitory effects of pyrrolidine dithiocarbamate on endotoxin-induced uveitis in Lewis rats. Invest Ophthalmol Vis Sci in press

8.Kawa S, Ota M, Yoshizawa K, Horiuchi A, Hamano H, Ochi Y, Nakayama K, Tokutake Y, Katsuyama Y, Saito S, Hasebe O, Kiyosawa K: HLA DRB1*0405-DQB1*0401 haplotype is major susceptible gene for sclerosing pancreatitis in the Japanese population. Gastroenterology in press

根岸　学　（京都大学・大学院生命科学研究科）

1.Yasui H, Katoh H, Yamaguchi Y, Aoki J, Fujita H, Mori K, Negishi M: Differential responses to nerve growth factor and epidermal growth factor in neurite outgrowth of PC12 cells are determined by Rac1 activation systems. J Biol Chem 276: 15298-15305, 2001

2.Yamaguchi Y, Katoh H, Yasui H, Mori K, Negishi M: RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway. J Biol Chem 276: 18977-18983, 2001

3.Nakamura K, Li Y-Q, Kaneko T, Katoh H, Negishi M: Prostaglandin EP3 receptor protein in serotonin and catecholamine cell groups. Neuroscience 103: 763-775, 2001

4.Choi S-Y, Choi B-H, Suh B-C, Chae H-D, Kim J-S, Shin M-J, Kang S-S, Negishi M, Kim K-T: Potentiation of PGE₂-mediated camp production during neuronal differentiation of human neuroblastoma SK-N-BE(2)C cells. J Neurochem 79: 303-310, 2001

5.Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, Mori K: ER stress-induced formation of transcription factor complex ERSF including NF-Y and activating transcription factors 6α and 6βthat activates the mammalian unfolded protein response. Mol Cell Biol 21: 1239-1248, 2001

6.Haze K, Okada T, Yoshida H, Yanagi H, Yura T, Negishi M, Mori K: Identification of the G13 gene product related to activating transcription factor 6 as a transcription activator of the mammalian unfolded protein response. Biochem J 355: 19-28, 2001

7.Katoh H, Harada A, Mori K, Negishi M: Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers. Mol Cell Biol in press

古市貞一　（理化学研究所・脳科学総合研究センター）

1.Kagami Y, Furuichi T: Investigation of differentially expressed genes during the development of mouse cerebellum. Gene Exp Patterns 1: 39-59, 2001

2.Iwasaki H, Chiba K, Uchiyama T, Yoshikawa F, Suzuki F, Ikeda M, Furuichi T, Mikoshiba K: Molecular characterization of the starfish inositol 1,4,5-trisphosphate receptor and its role during oocyte maturation and fertilization. J Biol Chem 277: 2763-2772, 2002

3.Uchiyama T, Yoshikawa F, Hishida A, Furuichi T, Mikoshiba K: A novel recombinant hyper-affinity Inositol 1,4,5-trisphosphate (IP3) absorbent traps IP3, resulting in specific inhibition of IP3-mediated calcium signaling. J Biol Chem in press

別所康全　（京都大学・ウイルス研究所）

1.Inoue T, Hojo M, Bessho Y, Tano Y, Lee JE, Kageyama R: Math3 and NeuroD regulate amacrine cell fate specification in the retina. Development 129: 831-842, 2002

2.Bessho Y, Sakata R, Komatsu S, Shiota K, Yamada S, Kageyama R: Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev 15: 2642-2647, 2001

3.Inoue C, Bae S-K, Takatsuka K, Inoue T, Bessho Y, Kageyama R: Math6, a bHLH gene expressed in the developing nervous system, promotes neuronal differentiation. Genes Cells 6: 977-986, 2001

4.Hirata H, Tomita K, Bessho Y, Kageyama R: Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain. EMBO J 20: 4454-4466, 2001

村上富士夫　（大阪大学・大学院基礎工学研究科）

1.Tashiro Y, Miyahara M, Shirasaki R, Okabe M, Heizmann CW, Murakami F: Local nonpermissive and oriented permissive cues guide vestibular axons to the cerebellum. Development 128: 973-981, 2001

2.Sawamoto K, Nakao N, Kobayashi K, Matsushita N, Takahashi H, Kakishita K, Yamamoto A, Yoshizaki T, Terashima T, Murakami F, Itakura T, Okano H: Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons labeled with a TH-GFP transgene. Proc Natl Acad Sci USA 98: 6423-6428, 2001

3.Shirasaki S, Murakami F: Crossing the floor plate triggers sharp turning of commissural axons. Dev Biol 236: 99-108, 2001

4.Otsuka T, Murakami F, Song WJ: Excitatory postsynaptic potentials trigger a plateau potential in rat subthalamic neurons at hyperpolarized states. J Neurophysiol 86: 1816-1825, 2001

5.Saito Y, Katsumaru H, Wilson CJ, Murakami F: Light and electron microscopic study of corticorubral synapses in adult cat: evidence for extensive synaptic remodeling during postnatal development. J Comp Neurol 440: 236-244, 2001

横田義史　（福井医科大学・医学部）

1.Wang S, Sdrulla A, Johnson JE, Yokota Y, Barres BA: A role for the helix-loop-helix protein Id2 in the control of oligodendrocyte development. Neuron 29: 603-614, 2001

2.Fujii Y, Kimoto H, Ishikawa K, Watanabe K, Yokota Y, Nakai N, Taketo A: Taxon-specific ζ-crystallin in Japanese tree frog (Hyla japonica) lens. J Biol Chem 276: 28134-28139, 2001

3.Tachibana A, Narumi O, Muguruma K, Yamamoto I, Shinkai Y, Yokota Y: Genomic organization and chromosomal mapping of the basic helix-loop-helix factor OUT (Tcf23/TCF23). Cytogenet Cell Genet 94: 23-25, 2001

4.Lasorella A, Boldrini R, Dominici C, Donfrancesco A, Yokota Y, Inserra A, Iavarone A: Id2 is critical for cellular proliferation and is the oncogenic effector of N-myc in human neuroblastoma. Cancer Res 62: 301-306, 2002

5.Greichmann M, Buchheim G, El-Bizri H, Yokota Y, Klockgether T, Kügler S, Bähr M, Weller M, Schulz JB: Identification of inhibitor-of-differentiation 2 as a modulator of neuronal apoptosis. J Neurochem in press

吉原良浩　（理化学研究所・脳科学総合研究センター）

1.Mizuno T, Kawasaki M, Nakahira M, Kagamiyama H, Kikuchi Y, Okamoto H, Mori K, Yoshihara Y: Molecular diversity in zebrafish NCAM family: three members with different VASE usage and distinct localization. Mol Cell Neurosi 18: 119-130, 2001

2.Kinoshita N, Mizuno T, Yoshihara Y: Adenovirus-mediated WGA gene delivery for transsynaptic labeling of mouse olfactory pathways. Chem Senses in press

若松義雄　（東北大学・大学院医学系研究科）

1.Endo Y, Osumi N, Wakamatsu Y: Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development. Development 129: 863-873, 2002