Published in Cell Reports March 22 2023

Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination

Researchers from University of Tsukuba identify a family of proteins involved in the regulation of fast twitch muscle fibers for fast, powerful movements and reveal its impacts on the performance of physical activities


Tsukuba, Japan—Different types of exercise encourage the formation of different types of muscle fibers, or the cells that make up your muscles. Slow twitch muscle fibers support endurance activities like long-distance running, while fast twitch fibers are needed for short, powerful movements such as those involved in heavy weight lifting. Now, researchers in Japan have shed new light on a family of proteins involved in the development of these ... Read more (University of Tsukuba Press Release)...

Cell Reports       DOI 10.1016/j.celrep.2023.112289
"Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination."

Research Outline (PDF In Japanese language)