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  1. Hata Y, Ohshima M, Ichisaka S, Wakita M, Fukuda M, Tsumoto T: BDNF expands ocular dominance columns in visual cortex in monocularly deprived and non-deprived kittens, but does not in adult cats. J Neurosci 20: RC57, 2000


  2. Kumura E, Kimura F, Taniguchi N, Tsumoto T: Brain-derived neurotrophic factor blocks long-term depression in solitary neurones cultured from rat visual cortex. J Physiol 524: 195-204. 2000


  3. Taniguchi N, Takada N, Kimura F, Tsumoto T: Actions of BDNF on evoked and spontaneous EPSCs dissociate with maturation of neurones cultured from rat visual cortex. J Physiol 527: 579-592, 2000


  4. Kohara K, Kitamura A, Morishima M, Tsumoto T: Activity-dependent transfer of brain-derived neurotrophic factor to postsynaptic neurons. Science 291: 2419-2423, 2001


  5. Katoh-Semba R, Takeuchi IK, Inaguma Y, Ichisaka S, Hata Y, Tsumoto T, Iwai M, Mikoshiba K, Kato K: Induction of brain-derived neurotrophic factor by convulsant drugs in the rat bran: Involvement of voltage-dependent calcium channels. J Neurochem 77: 71-83, 2001


  6. Jiang B, Akaneya Y, Ohshima M, Ichisaka S, Hata Y, Tsumoto T: Brain-derived neurotrophic factor induces long-lasting potentiation of synaptic transmission in visual cortex in vivo in young rats, but does not in the adult. Eur J Neurosci 14: 1219-1228, 2001


  7. Ohshima M, Hata Y, Ichisaka S, Wakita M, Fukuda M, Kameyama K, Tsumoto T: Chronic, electrical stimulation of afferents from one eye changes ocular dominance of visual cortical neurones in kittens. J Neurophysiol 88: 2147-2151, 2002


  8. Ichisaka S, Katoh-Semba R, Hata Y, Ohshima M, Kameyama K, Tsumoto T: Activity-dependent changes in the protein level of brain-derived neurotrophic factor but no change in other neurotrophins in the visual cortex of young and adult ferrets. Neuroscience 117: 361-371, 2003


  9. Akaneya Y, Altibaev RSh, Bayazitov IT, Kinoshita S, Voronin LL, Tsumoto T: Low-frequency depression of synaptic responses recorded from rat visual cortex. Neuroscience 117: 305-320, 2003


  10. Yasuda H, Higashi H, Kudo Y, Inoue T, Hata Y, Mikoshiba K, Tsumoto T: Imaging of calcineuin activated by long-term depression-inducing synaptic inputs in living neurons of rat visual cortex. Eur J Neurosci 17: 287-297, 2003


  11. Jiang B, Akaneya Y, Hata Y, Tsumoto T: Long-term depression is not induced by low frequency stimulation in rat visual cortex in vivo: A possible preventing role of endogenous BDNF. J Neurosci 23: 3761-3770, 2003


  12. Salami M, Itami C, Tsumoto T, Kimura F: Change of conduction velocity by regional myelination yields constant latency irrespective of distance between thalamus and cortex. Proc Natl Acad Sci USA 100: 6174-6179, 2003


  13. Kohara K, Kitamura A, Adachi N, Nishida M, Itami C, Nakamura S, Tsumoto T: Inhibitory, but not excitatory cortical neurons require presynaptic BDNF for dendritic development, as revealed by chimera cell culture. J Neurosci 23: 6123-6131, 2003


  14. Katoh-Semba R, Ichisaka S, Hata Y, Tsumoto T, Eguchi K, Miyazaki N, Matsuda M, Takeuchi IK, Kato K: Induction of brain-derived neurotrophic factor by convulsant drugs in the rat bran: Involvement of voltage-dependent calcium channels. J Neurochem 86: 660-668, 2003


  15. Itami C, Kimura F, Kohno T, Matsuoka M, Ichikawa M, Tsumoto T, Nakamura S: BDNF-dependent unmasking of gsilenth synapses in developing mouse barrel cortex. Proc Natl Acad Sci USA 100: 13069-13074, 2003


  16. Palizvan MR, Sohya K, Kohara K, Maruyama A, Yasuda H, Kimura F, Tsumoto T: Brain-derived neurotrophic factor increases inhibitory synapses, revealed in solitary neurons cultured from rat visual cortex. Neuroscience 126: 955-966, 2004


  17. Jiang B, Kitamura A, Yasuda H, Sohya K, Maruyama A, Yanagawa Y, Obata K, Tsumoto T: Brain-derived neurotrophic factor acutely depresses excitatory synaptic transmission to GABAergic neurons in visual cortical slices. Eur J Neurosci 20: 709-718, 2004


  18. Yanagisawa T, Tsumoto T, Kimura F: Transiently higher release probability during the critical period at thalamocortical transmission in the barrel cortex. Eur J Neurosci 20: 3006-3018, 2004


  19. Akaneya Y, Jiang B, Tsumoto T: RNAi-induced gene silencing by local electroporation in targeting brain region. J Neurophysiol 93: 594-602, 2005


  20. Hori K, Yasuda H, Konno D, Maruoka H, Tsumoto T, Sobue K: NMDA receptor-dependent synaptic translocation of insulin receptor substrate p53 via protein kinase C signaling. J Neurosci 25: 2670-2681, 2005


  21. Adachi N, Kohara K, Tsumoto T: Difference in trafficking of brain-derived neurotrophic factor between axons and dendrites of cortical neurons, revealed by live-cell imaging. BMC Neurosci 6: 42, 2005


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  1. Miyagi Y, Yamashita T, Fukaya M, Sonoda T, Okuno T, Yamada K, Watanabe M, Nagashima Y, Aoki I, Okuda K, Mishina M, Kawamoto S: Delphilin: A novel PDZ- and Formin homology (FH)-domain containing protein, which interacts with glutamate receptor δ2 subunit. J Neurosci 22: 803-814, 2002


  2. Oshima S, Fukaya M, Nagashima M, Shirakawa T, Oguchi H, Watanabe M: Early onset of NMDA receptor GluRε1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus. Neurosci Res 43: 239-250, 2002


  3. Nakazawa K, Quirk MC, Chitwood RA, Watanabe M, Yeckel MF, Sun LD, Kato A, Carr CA, Johnston D, Wilson MA, Tonegawa S: Requirement for hippocampal CA3 NMDA receptors in associative memory recall. Science 297: 211-218, 2002


  4. Ichikawa R, Miyazaki T, Kano M, Hashikawa T, Tatsumi H, Sakimura K, Mishina M, Inoue Y, Watanabe M: Distal extension of climbing fiber territory and multiple innervation caused by aberrant wiring to adjacent spiny branchlets in cerebellar Purkinje cells lacking glutamate receptor GluRε2. J Neurosci 22: 8487-8503, 2002


  5. Miura M, Watanabe M, Offermanns S, Simon MI, Kano M: Group I mGluR signaling via Gαq/Gα11 secures the induction of long-term potentiation in the hippocampal area CA1. J Neurosci 22: 8379-8390, 2002


  6. Toyooka K, Iritani S, Makifuchi T, Shirakawa O, Kitamura K, Maeda K, Nakamura R, Niizato K, Watanabe M, Kakita A, Takahashi H, Someya T, Nawa N: Selective reduction of a PDZ protein, SAP-97, in the prefrontal cortex of patients with chronic schizophrenia. J Neurochem 83: 797-806, 2002


  7. Ohtsuki S, Tachikawa M, Takanaga H, Shimizu H, Watanabe M, Hosoya K, Terasaki T: The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain. J Cereb Blood Flow Metab 22: 1327-1335, 2002


  8. Nakamura K, Tanoue K, Satoh T, Takekawa M, Watanabe M, Shima H, Kikuchi K: A novel low-molecular-mass dual-specificity phosphatase, LDP-2, with a naturally occurring substitution that affects substrate specificity. J Biochem 132: 463-470, 2002


  9. Kinoshita M, Kojima S, Sato K, Watanabe M, Urano A, Ito E: Multiple-site optical recording for characterization of functional synaptic organization of the optic tectum of rainbow trout. Eur J Neurosci 16: 868-876, 2002


  10. Saito T, Fujimoto W, Yanase H, Watanabe M, Iwanaga T: Immunohistochemical localization of serotonin transporter in the adrenal chromaffin cells and mast cells of mice. Biomed Res 23: 277-286, 2002


  11. Yamada K, Watanabe M: Cytodifferentiation of Bergmann glia and its relationship with Purkinje cells. Anat Sci Int 77: 94-108, 2002


  12. Sakai K, Shimizu H, Koike T, Furuya S, Watanabe M: Neutral amino acid transporter ASCT1 is preferentially expressed in L-Ser-synthetic/storing glial cells in the mouse with transient expression in developing capillaries. J Neurosci 23: 550-560, 2003


  13. Kakizawa S, Yamada K, Watanabe M, Kano M: Effects of insulin-like growth factor I on climbing fiber synapse elimination during cerebellar development. Eur J Neurosci 17: 545-554, 2003


  14. Fukaya M, Kato A, Lovett C, Tonegawa S, Watanabe M: Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice. Proc Natl Acad Sci USA 100: 4855-4860, 2003


  15. Shibata T, Watanabe M, Ichikawa R, Ameda K, Koyanagi T: Transient neonatal expression of NR2B/2D subunit mRNAs of the N-methyl-D-aspartate receptor in the parasympathetic preganglionic neurons in the rat spinal cord. Dev Brain Res 140: 263-268, 2003


  16. Somogyi P, Dalezios Y, Luján R, Roberts DB, Watanabe M, Shigemoto R: High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurones in the rat hippocampus. Eur J Neurosci 17: 2503-2520, 2003


  17. Miyazaki T, Fukaya M, Shimizu H, Watanabe M: Developmental switching of vesicular glutamate transporters at parallel fiber-Purkinje cell synapses. Eur J Neurosci 17: 2563-2572, 2003


  18. Sassoé-Pngnetto M, Utvik JK, Camoletto P, Watanabe M, Stephenson FA, Bredt DS, Otternen OP: Organization of postsynaptic density proteins and glutamate receptors in axodendritic and dendrodendritic synapses of the rat olfactory bulb. J Comp Neurol 463: 237-248, 2003


  19. Miyata M, Kashiwadani H, Fukaya M, Hayashi T, Wu D, Suzuki T, Watanabe M, Kawakami Y: Role of thalamic phospholipase Cβ4 mediated by metabotropic glutamate receptor type 1 in inflammatory pain. J Neurosci 23: 8098-8108, 2003


  20. Jourdi H, Iwakura Y, Narisawa-Saito M, Ibaraki K, Xiong H, Watanabe M, Hayashi Y, Takei N, Nawa H: Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Dev Biol 263: 216-230, 2003


  21. Furuya S, Watanabe M: Novel neuroglial and glioglial relationships mediated by L-serine metabolism. Arch Histol Cytol 66: 109-121, 2003


  22. Yamashita N, Sakai K, Furuya S, Watanabe M: Selective expression of L-serine synthetic enzyme 3PGDH in Schwann cells, perineuronal glia, and endoneurial fibroblasts along sciatic nerves and its upregulation after crush injury. Arch Histol Cytol 66: 429-436, 2003


  23. Takahashi Y, Mori H, Mishina M, Watanabe M, Fujiwara T, Shimomura J, Aiba H, Miyajima T, Saito Y, Nezu A, Nishida H, Imai K, Saskaguchi N, Kondo N: Autoantibodies to NMDA receptor in patients with chronic forms of epilepsia partialis continua. Neurology 61: 891-896, 2003


  24. Miyazaki M, Hashimoto K, Shin H-S, Kano M, Watanabe M: P/Q-type Ca2+ channel a1A regulates synaptic competition on developing cerebellar Purkinje cells. J Neurosci 24: 1734-1743, 2004


  25. Kinoshita N, Kimura K, Matsumoto N, Watanabe M, Fukaya M, Ide C: Mammalian septin Sept2 modulates the activity of GLAST, a glutamate transporter in astrocytes. Genes Cells 9: 1-14, 2004


  26. Yoshida K, Furuya S, Osuka S, Mitoma J, Shinoda Y, Watanabe M, Azuma N, Tanaka H, Hashikawa T, Itohara S, Hirabayashi Y: Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality. J Biol Chem 279: 3573-3577, 2004


  27. Somogyi J, Baude A, Omori Y, Shimizu H, Mestikawy SE, Fukaya M, Ryuichi S, Watanabe M, Somogyi P: GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. Eur J Neurosci 19: 552-569, 2004


  28. Fukudome Y, Ohno-Shosaku T, Matsui M, Omori Y, Fukaya M, Taketo M, Watanabe M, Manabe M, Kano M: Two distinct classes of muscarinic action on hippoccampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signaling. Eur J Neurosci 19: 2682-2692, 2004


  29. Nakashima T, Tomi M, Katayama K, Tachikawa M, Watanabe M, Terasaki T, Hosoya K: Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-brain barrier. J Neurochem 89: 1454-1461, 2004


  30. Tachikawa M, Fukaya M, Terasaki T, Ohtsuki S, Watanabe M: Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-Mi and CK-B suggest novel neuron-glial relationship for brain energy homeostasis. Eur J Neurosci 20: 144-160, 2004


  31. Ferraguti F, Cobden P, Pollard M, Cope D, Shigemoto R, Watanabe M, Somogy P: Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1 region of the rat hippocampus. Hippocampus 14: 193-215, 2004


  32. Nagy GG, Al-Ayyan M, Andrew D, Fukaya M, Watanabe M, Todd AJ: Widespread expression of the AMPA receptor GluR2 subunit at glutamatergic synapses in the rat spinal cord and phosphorylation of GluR1 in response to noxious stimulation revealed with an antigen unmasking method. J Neurosci 24: 5766-5777, 2004


  33. Abe M, Fukaya M, Yagi T, Mishina M, Watanabe M, Sakimura K: NMDA Receptor GluRε/NR2 subunits are essential for postsynaptic localization and protein stability of GluRζ1/NR1 subunit. J Neurosci 24: 9292-9304, 2004


  34. Hama K, Aoki J, Fukaya M, Kishi Y, Sakai T, Suzuki R, Ohta H, Yamori T, Watanabe M, Chun J, Arai H: Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J Biol Chem 279: 17634-17639, 2004


  35. Oshima S, Yamada K, Shirakawa T, Watanabe M: Changes of high-affinity choline transporter expression during degeneration and regeneration of hypoglossal nerves in mice. Neurosci Lett 365: 97-101, 2004


  36. Kawano H, Nakatani T, Mori T, Ueno S, Fukaya M, Abe A, Kobayashi M, Toda F, Watanabe M, Matsuoka I: Identification and characterization of novel developmentally regulated neural-specific proteins, BRINP family. Mol Brain Res 125: 60-75, 2004


  37. Hori S, Ohtsuki S, Tachikawa M, Kimura N, Kondo T, Watanabe M, Nakashima E, Terasaki T: Functional expression of rat ABCG2 and its enhancement by astrocyte-derived soluble factor(s). J Neurochem 90: 526-536, 2004


  38. Kitamura HW, Hamanaka H, Watanabe M, Wada K, Yamazaki C, Fujita SC, Manabe T, Nukina N: Age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein E. Neurosci Lett 369: 173-178, 2004


  39. Nakatsu F, Okada M, Mori F, Kamazawa N, Iwasa H, Zhu G, Kasagi Y, Kamiya H, Harada A, Nishimura K, Takeuchi A, Miyazaki T, Watanabe M, Yuasa S, Manabe T, Wakabayashi K, Kaneko S, Saito T, Ohno H: Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor. J Cell Biol 167: 293-302, 2004


  40. Oguro K, Miyawaki T, Yokota H, Kato K, Kamiya T, Katayama Y, Fukaya M, Watanabe M, Shimazaki K: Upreguration of GluR2 decrease intracellular Ca2+ following ischemia in developing gerbils. Neurosci Lett 364: 101-105, 2004


  41. Nakamura M, Sato K, Fukaya M, Araishi K, Aiba A, Kano M, Watanabe M: Signaling complex formation of phospholipase Cβ4 with mGluR1α and IP3R1 at the perisynapse and endoplasmic reticulum in the mouse brain. Eur J Neurosci 20: 2929-2944, 2004


  42. Yamazaki M, Ohno-Shosaku T, Fukaya M, Kano M, Watanabe M, Sakimura K: A novel action of stargazin as an enhancer of AMPA receptor activity. Neurosci Res 50: 369-374, 2004


  43. Nagy GG, Watanabe M, Fukaya M, Todd R: Synaptic distribution of the NR1, NR2A, and NR2B subunits of the NMDA receptor in the rat lumbar spinal cord revealed with an antigen unmasking technique. Eur J Neurosci 20: 3301-3312, 2004


  44. Hirai H, Miyazaki T, Kakegawa W, Matsuda S, Mishina M, Watanabe M, Yuzaki M: Rescue of abnbormal phenotypes of the δ2 glutamate receptor-null mice by mutant δ2 transgenes. EMBO Rep 6: 90-95, 2005


  45. Kinoshita M, Fuyaka M, Tojima T, Kojima S, Ando H, Watanabe M, Urano A, Ito E: Retinotectal transmission in the optic tectum of rainbow trout. J Comp Neurol 484: 249-259, 2005


  46. Fukaya M, Hayashi Y, Watanabe M: NR2-to-NR3B subunit conversion of NMDA receptor in early postnatal motoneurons. Eur J Neurosci 21: 1432-1436, 2005


  47. Takeuchi T, Miyazaki T, Watanabe M, Mori H, Sakimura K, Mishina M: Control of synaptic connection by glutamate receptor δ2 in the mature cerebellum. J Neurosci 484: 249-259, 2005


  48. Nakashima T, Tomi M, Tachikawa M, Watanabe M, Terasaki T, Hosoya K: Evidence for creatine biosynthesis in Müller glial cells Glia 52: 47-52, 2005


  49. Taniguchi M, Masuda T, Fukaya M, Kataoka H, Mishina M, Yaginuma H, Watanabe M, Shimizu T: Identification and characterization of a novel member of murine semaphorin family. Genes Cells 10: 785-792, 2005


  50. Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, Nishimura Y.V, Fukuda A, Matsuo N, Sone M, Watanabe M, Terashima T, Wright CVE, Kawaguchi Y, Nakao K, Nabeshima Y: Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron 47: 201-213, 2005


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  1. Funatsu N, Inoue T, Nakamura S: Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarrayFidentification of several region- and layer-specific genes. Cereb Cortex 14: 1031-1044, 2004


  2. Ohira K, Kumanogoh H, Sahara Y, Homma KJ, Hirai H, Nakamura S, Hayashi H: A truncated tropomyosine-related kinase B receptor, T1, regulates glial cell morphology via Rho GDP dissociation Inhibitor 1. J Neurosci 25: 1343-1353, 2005


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  1. Grifone R, Laclef C, Spitz F, Llpez S, Demingon J, Guidotti J-E, Kawakami K, Xu P, Kelly R, Petrof BJ, Daegelen D, Concordet J-P, Maire P: Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype. Mol Cell Biol 24: 6253-6267, 2004


  2. Coletta RD, Christensen K, Reichenberger KJ, Lamb J, Micomonaco D, Huang L, Wolf DM, Müller-Tidow C, Golub TR, Kawakami K, Ford HL: The Six1 homeoprotein stimulates tumorigenesis via reactivation of the germ line and embryonic specific cyclin A1. Proc Natl Acad Sci USA 101: 6478-6483, 2004


  3. Ikeda K, Onimaru H, Yamada J, Inoue K, Ueno S, Onaka T, Toyoda H, Arata A, Ishikawa T, Taketo MM, Fukuda A, Kawakami K: Malfunction of respiratory related neuronal activity in Na+, K+-ATPase α2 subunit-deficient mice is due to abnormal Cl- homeostasis in brainstem neurons. J Neurosci 24: 10693-10701, 2004


  4. Ando Z, Sato S, Ikeda K, Kawakami K: Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4. FEBS J 272: 3026-3041, 2005


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  1. Tojima T, Ito E: A cyclic AMP-regulated negative feedforward system for neuritogenesis revealed in a neuroblastoma x glioma hybrid cell. Neuroscience 104: 583-591, 2001


  2. Kubo M, Odai K, Sugimoto T, Ito E: Quantum chemical study of agonist-receptor vibrational interactions for activation of the glutamate receptor. J Biochem 129: 869-874, 2001


  3. Odai K, Sugimoto T, Hatakeyama D, Kubo M, Ito E: A theoretical study of electronic and structural states of neurotransmitters: γ-aminobutyric acid and glutamic acid. J Biochem 129: 909-915, 2001


  4. Shiga H, Tojima T, Ito E: Ca2+ signaling regulated by an ATP dependent autocrine mechanism in astrocytes. NeuroReport 12: 2619-2622, 2001


  5. Yamane Y, Shiga H, Asou H, Ito E: Gap junctional channel inhibition alters actin organization and calcium propagation in rat cultured astrocytes. Neuroscience 112: 593-603, 2002


  6. Kawahara K, Saito M, Nakajima T, Sato H, Tanaka M, Tojima T, Ito E: Increased resistance to nitric oxide cytotoxicity associated with differentiation of neuroblastoma-glioma hybrid (NG108-15) cells. Free Radic Res 36: 545-554, 2002


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  1. Kobayashi M, Imamura K, Sugai T, Onoda N, Yamamoto M, Komai S, Watanabe Y: Selective suppression of horizontal propagation in rat visual cortex by norepinephrine. Eur J Neurosci 12: 264-272, 2000


  2. Yoshimura Y, Sato H, Imamura K, Watanabe Y: Properties of horizontal and vertical inputs to pyramidal cells in the superficial layers of the cat visual cortex. J Neurosci 20: 1931-1940, 2000


  3. Komai S, Matsuyama T, Matsumoto K, Kato K, Kobayashi M, Imamura K, Yoshida S, Shiosaka S: Neuropsin regulates an early phase of schaffer-collateral long-term potentiation in the murine hippocampus. Eur J Neurosci 12: 1479-1486, 2000


  4. Kataoka Y, Morii H, Imamura K, Ciu Y, Kobayashi M, Watanabe Y: Control of neurotransmission, behavior, and development by photo-dynamic manipulation of tissue redox state of brain targets. Eur J Neurosci 12: 4417-4423, 2000


  5. Nakadate K, Imamura K, Watanabe Y: Effects of monocular deprivation on the expression pattern of alpha-1 and beta-1 adrenergic receptors in the kitten visual cortex. Neurosci Res 40: 155-162, 2001


  6. Hashimoto R, Nakamura Y, ImamuraK, NakadateK, Kashiwagi Y, MatsumotoN, Takeda M: Visual stimulation-induced phosphorylation of neurofilament-L in the visual cortex of dark-reared rats. Eur J Neurosci 14: 1237-1245, 2001


  7. Yamamoto M, Imamura K, Kobayashi M, Nakadate K, Yokoyama C, Watanabe Y, Yamamoto M, Negi A: N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine reduces intracellular calcium response to noradrenaline in rat visual cortex. Neuroscience 107: 209-218, 2001


  8. Richter H, Magnusson S, Imamura K, Fredrikson M, Okura M, Watanabe Y, Langstrom B: Long-term adaptation to prism-induced inversion of the retinal images. Exp Brain Res 144: 445-457, 2002


  9. Kobayashi M, Sasabe T, Takeda M, Kondo Y, Yoshikubo S, Imamura K, Onoe H, Sawada T, Watanabe Y: Functional anatomy of chemical senses in the alert monkey revealed by positron emission tomography. Eur J Neurosci 16: 975-980, 2002


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  1. Ino M, Yoshinaga T, Wakamori M, Miyamoto N, Takahashi E, Sonoda J, Kagaya T, Oki T, Nagasu T, Nishizawa Y, Tanaka I, Imoto K, Aizawa S, Koch S, Schwartz A, Niidome T, Sawada K, Mori Y: Functional disorder of sympathetic nervous system in mice lacking α1B subunit (Cav 2.2) of N-type calcium channel. Proc Natl Acad Sci USA 98: 5323-5328, 2001


  2. Sugawara T, Tsurubuchi Y, Agarwala KL, Ito M, Fukuma G, Mazaki-Miyazaki E, Nagafuji H, Noda M, Imoto K, Wada K, Mitsudome A, Kaneko S, Montal M, Nagata K, Hirose S, Yamakawa K: A missense mutation of the Na+ channel alphaII subunit gene Nav1.2 in a patient with febrile and afebrile seizures causes channel dysfunction. Proc Natl Acad Sci USA 98: 6384-6389, 2001


  3. Hatakeyama S, Wakamori M, Ino M, Miyamoto N, Takahashi E, Yoshinaga T, Sawada K, Imoto K, Tanaka I, Yoshizawa T, Nishizawa Y, Mori Y, Niidome T, Shoji S: Differential nociceptive responses in mice lacking the α1B subunit of N-type Ca2+ channels. NeuroReport 12: 2423-2427, 2001


  4. Hara Y, Wakamori M, Ishii M, Maeno E, Nishida M, Yoshida T, Yamada H, Shimizu S, Mori E, Kudoh J, Shimizu N, Kurose H, Okada Y, Imoto K, Mori Y: LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell 9: 163-173, 2002


  5. Morii T, Sato S, Hagihara M, Mori Y, Imoto K, Makino K: Structure-based design of a leucine zipper protein with new DNA contacting region. Biochemistry 41: 2177-2183, 2002


  6. Morii T, Sugimoto K, Makino K, Otsuka M, Imoto K, Mori Y: A new fluorescent biosensor for inositol trisphosphate. J Am Chem Soc 12: 1138-1139, 2002


  7. Matsushita K, Wakamori M, Rhyu I-J, Arii T, Oda S, Mori Y, Imoto K: Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice. J Neurosci 22: 4388-4398, 2002


  8. Kato K, Wakamori M, Mori Y, Imoto K, Kitamura K: Inhibitory effects of cilnidipine on peripheral and brain N-type Ca2+ channels expressed in BHK cells. Neuropharmacology 42: 1099-1108, 2002


  9. Ichida S, Abe J, Sugimoto W, Uematsu M, Komoike K, Imoto K, Mori M, Wada T, Minami T, Kakutani K: Antigen selectivity characteristic of polyclonal antibodies against omega-conotoxin GVIA and N-type voltage-dependent calcium channels. Neurochem Res 28: 789-796, 2003


  10. Akiba I, Seki T, Mori M, Iizuka M, Nishimura S, Sasaki S, Imoto K, Barsoumian EL: Stable expression and characterization of human PN1 and PN3 sodium channels. Receptors Channels 9: 291-299, 2003


  11. Mori M, Konno T, Morii T, Nagayama K, Imoto K: Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe. Biochem Biophys Res Commun 307: 290-296, 2003


  12. Matsuyama Z, Yanagisawa NK, Aoki Y, Black JL 3rd, Lennon VA, Mori Y, Imoto K, Inuzuka T: Polyglutamine repeats of spinocerebellar ataxia 6 impair the cell-death-preventing effect of CaV2.1 Ca2+ channel --- loss-of-function cellular model of SCA6. Neurobiol Dis 17: 198-204, 2004


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  1. Ebihara T, Komiya Y, Izumi-Nakaseko H, Adachi-Akahane S, Okabe S, Okamura Y: Coexpression of a Cav1.2 protein lacking an N-terminus and the first domain specifically suppresses L-type calcium channel activity. FEBS Lett 529: 203-207, 2002


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  1. Tanaka T, Yazawa I, Sato K, Momose-Sato Y, Kamino K: Physiological consistency in trial-to-trial variation in intrinsic-optical responses to single-whisker movement in the rat D1-barrel cortex. Neurosci Res 36: 193-207, 2000


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  6. Mochida H, Sato K, Arai Y, Sasaki S, Yazawa I, Kamino K, Momose-Sato Y: Multiple-site optical recording reveals embryonic organization of synaptic networks in the chick spinal cord. Eur J Neurosci 13: 1547-1558, 2001


  7. Yazawa I, Sasaki S, Mochida H, Kamino K, Momose-Sato Y, Sato K: Developmental changes in trial-to-trial variations in whisker barrel responses studied using intrinsic optical imaging: Comparison between normal and de-whiskered rats. J Neurophysiol 86: 392-401, 2001


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  9. Sato K, Nariai T, Sasaki S, Yazawa I, Mochida H, Miyakawa N, Momose-Sato Y, Kamino K, Ohta Y, Hirakawa K, Ohno K: Intraoperative intrinsic optical imaging of neuronal activity from subdivisions of the human primary somatosensory cortex. Cereb Cortex 12: 269-280, 2002


  10. Sato K, Mochida H, Yazawa I, Sasaki S, Momose-Sato Y: Optical approaches to functional organization of glossopharyngeal and vagal motor nuclei in the embryonic chick hindbrain. J Neurophysiol 88: 383-393, 2002


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  16. Miyakawa N, Yazawa I, Sasaki S, Momose-Sato Y, Sato K: Optical analysis of acute spontaneous epileptiform discharges in the in vivo rat cerebral cortex. NeuroImage 18: 622-632, 2003


  17. Sato K, Momose-Sato Y: Optical detection of developmental origin of synaptic function in the embryonic chick vestibulocochlear nuclei. J Neurophysiol 89: 2315-3224, 2003


  18. Sasaki S, Sato K, Shinomiya K, Momose-Sato Y: Postnatal changes in intrinsic optical responses to peripheral nerve stimulation in the in vivo rat spinal cord. NeuroImage 20: 2126-2134, 2003


  19. Momose-Sato Y, Honda Y, Sasaki H, Sato K: Optical mapping of the functional organization of the rat trigeminal nucleus: Spatial and temporal dynamics of sensory information transfer during embryogenesis. J Neurosci 24: 1366-1376, 2004


  20. Sato K, Miyakawa N, Momose-Sato Y: Optical survey of neural circuit formation in the embryonic chick vagal pathway. Eur J Neurosci 19: 1217-1225, 2004


  21. Sato K, Momose-Sato Y: Optical mapping reveals developmental dynamics of Mg2+-/APV-sensitive components of glossopharyngeal glutamatergic EPSPs in the embryonic chick NTS. J Neurophysiol 92: 2538-2547, 2004


  22. Miyakawa N, Sato K, Momose-Sato Y: Optical detection of neural function in the chick visual pathway in the early stages of embryogenesis. Eur J Neurosci 20: 1133-1144, 2004


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  7. Saitoh N, Hori T, Takahashi T: Activation of the epsilon isoform of protein kinase C in the mammalian nerve terminal. Proc Natl Acad Sci USA 98: 14017-14021, 2001


  8. Sahara Y, Takahashi T: Quantal components of the excitatory postsynaptic currents at a rat central auditory synapse. J Physiol 536: 189-197, 2001


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  10. Kajikawa Y, Saitoh N, Takahashi T: GTP-binding protein bgsubunits mediate presynaptic calcium current inhibition by GABAB receptor. Proc Natl Acad Sci USA 98: 8054-8058, 2001


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  2. Inoue K, Terashima T, Nishikawa T, Takumi T: Fez1 is layer-specifically expressed in the adult mouse neocortex. Eur J Neurosci 20: 2909-2916, 2004


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  4. Kani S, Oishi I, Yamamoto H, Yoda A, Suzuki H, Nomachi A, Iozumi K, Nishita M, Kikuchi A, Takumi T, Minami Y: The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase I epsilon. J Biol Chem 279: 50102-50109, 2004


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  2. Higgins GA, Kew JNC, Richards JG, Takeshima H, Jenck F, Adam G, Wichman J, Kemp JA, Grottick AJ: A combined pharmacological and genetic approach to investigate the role of orphanin FQ in learning and memory. Eur J Neurosci 15: 911-922, 2002


  3. Nishi M, Hashimoto K, Kuriyama K, Komazaki S, Kano M, Shibata S, Takeshima H: Motor discoordination in mutant mice lacking junctophilin type 3. Biochem Biophys Res Commun 292: 318-324, 2002


  4. Uehara A, Yasukouchi M, Imanaga I, Nishi M, Takeshima H: Store-operated Ca2+ entry irrelevant to Ca2+ release channel and junctional membrane complex in heart muscle cells. Cell Calcium31: 89-96, 2002


  5. Pan Z, Yang D, Nagaraj RJ, Nosek TA, Nishi M, Takeshima H, Cheng H, Ma J: Dysfunction of store-operated Ca2+ channel in muscle cells lacking mg29 gene. Nat Cell Biol 4: 379-383, 2002


  6. Komazaki S, Ito K, Takeshima H, Nakamura H: Deficiency of triad formation in developing skeletal muscle cells lacking junctophilin type 1. FEBS Lett 524: 225-229, 2002


  7. Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M: Delta/Notch-like EGF-related receptor (DNER), a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons. J Biol Chem 277: 25400-25407, 2002


  8. Houtani T, Ikeda M, Kase M, Sato K, Sakuma S, Kakimoto S, Ueyama T, Munemoto Y, Takeshima H, Sugimoto T: A subset of nociceptin/orphanin FQ receptor-expressing neurons in the anterior hypothalamic area, as revealed in mice with lacZ reporter gene. Neurosci Lett 335: 217-219, 2003


  9. Inoue M, Kawashima T, Takeshima H, Calo G, Inoue A, Nakata Y, Ueda H: In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord. J Pharmacol Exp Ther 305: 495-501, 2003


  10. Komazaki S, Nishi M, Takeshima H: Abnormal junctional membrane structures in cardiac myocytes expressing ectopic junctophilin type 1. FEBS Lett 542: 69-73, 2003


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  12. Kurebayashi N, Takeshima H, Nishi M, Murayama T, Suzuki E, Ogawa Y: Changes in Ca2+ handling in MG29-deficient skeletal muscle. Biochem Biophys Res Commun 310: 1266-1272, 2003


  13. Nishi M, Sakagami H, Komazaki S, Kondo H, Takeshima H: Coexpression of junctophilin type 3 and type 4 in brain. Mol Brain Res 110: 102-110, 2003


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  15. Koizumi M, Midorikawa N, Takeshima H, Murphy NP: Exogenous, but not endogenous nociceptin modulates mesolimbic dopamine release in mice. J Neurochem 89: 257-263, 2004


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  18. Sakakibara T, Nemoto Y, Nukiwa T, Takeshima H: Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis. FEBS Lett 566: 294-300, 2004


  19. Andoh T, Yageta Y, Takeshima H, Kuraishi Y: Intradermal nociceptin elicits itch-associated responses through leukotriene B4 in mice. J Invest Dermatol 123: 196-201, 2004


  20. Minamisawa S, Oshikawa J, Takeshima H, Hoshijima M, Wang Y, Chien KR, Ishikawa Y, Matsuoka R: Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun 325: 852-856, 2004


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“c’†@‰ëŽ÷@i‹ž“s•{—§ˆã‰È‘åŠwEˆãŠw•”j
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  5. Hirofuji C, Nakatani T, Ishihara A, Tanaka M, Itoh K, Itoh K, Katsuta S, Ibata Y: Cell size and succinate dehydrogenase activity of different types of fibers in different regions of tibialis anterior muscle in mice and rats. Acta Histochem Cytochem 33: 295-303, 2000


  6. Sugano T, Yagita K, Ibata Y, Nagatsu I, Tanaka M, Yamaguchi S, Okamura H: Morphological survey of reserpine|induced tyrosine hydroxylase in brainstem dopaminergic, noradrenergic, and adrenergic neurons with special reference to their projection fibers. Biomed Res 21: 269-282, 2000


  7. Bamba H, Uno T, Tamada Y, Tanaka M, Ibata Y, Hisa Y: Relationship between nitric oxide synthase and heme oxygenase-2 in the canine esophagus. Acta Histochem Cytochem 34: 9-13, 2001


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  9. Matsuda T, Tamada Y, Hayashi S, Iijima N, Tanaka M, Yamada H, Utsunomiya K, Kudo M, Kurokawa K, Kataoka K, Yanaihara N, Nagasawa S, Ibata Y: Secretion of bax-like protein into systemic circulation from the posterior pituitary in the rat hypothalamo-posterior pituitary system. Acta Histochem Cytochem 34: 119-128, 2001


  10. Nishiyama K, Yagita K, Yamaguchi S, Kitamura S, Matsuo T, Uno T, Tanaka M, Hisa Y, Ibata Y, Okamura H: Tyrosine hydroxylase and NADPH-diaphorase in the rat nodose ganglion: colocalization and central projection. Acta Histochem Cytochem 34: 135-141, 2001


  11. Amaya F, Tanaka M, Hayashi S, Tanaka Y, Ibata Y: Hypothalamo-pituitary-adrenal axis sensitization after chronic salt loading. Neuroendocrinology 73: 185-193, 2001


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  13. Iijima N, Matsumoto Y, Yano T, Tanaka M, Yamamoto T, Kakihara K, Kataoka Y, Tamada Y, Matsumoto H, Suzuki N, Hinuma S, Ibata Y: A novel function of prolactin-releasing peptide in thecontrol of growth hormone via secretion of somatostatin from the hypothalamus. Endocrinology 142: 3239-3243, 2001


  14. Fukusumi S, Habata Y, Yoshida H, Iijima N, Kawamata Y, Hosoya M, Fujii R, Hinuma S, Kitada C, Shintani Y, Suenaga M, Onda H, Nishimura O, Tanaka M, Ibata Y, Fujino M: Characteristics and distribution of endogenous RFamide-related peptide-1. Biochim Biophys Acta 1540: 221-232, 2001


  15. Hayashi S, Ueda M, Amaya F, Matsuda T, Tamada Y, Ibata Y, Tanaka M: Serotonin modulates expressions of VIP and GRP mRNA via the 5-HT1B receptor in the suprachiasmatic nucleus of the rat. Exp Neurol 171: 285-292, 2001


  16. Ishihara A, Ohira Y, Tanaka M, Nishikawa W, Ishioka N, Higashibata A, Izumi R, Shimazu T, IbataY: Cell body size and succinate dehydrogenase activity of spinal motoneurons innervating the soleus muscle in mice, rats, and cats. Neurochem Res 26: 1301-1304, 2001


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“›ˆä@˜a‹`@iL“‡‘åŠwE‘‡‰ÈŠw•”j
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  2. Sakamoto H, Ukena K, Tsutsui K: Activity and localization of 3β-hydroxysteroid dehydrogenase/ƒ¢5-ƒ¢4-isomerase in the zebrafish central nervous system. J Comp Neurol 439: 291-305, 2001


  3. Ubuka T, Sakamoto H, Li D, Ukena K, Tsutsui K: Developmental changes in galanin in lumbosacral sympathetic ganglionic neurons innervating the avian uterine oviduct and galanin induction by sex steroids.J Endocrinol 170: 357-368, 2001


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  5. Matsunaga M, Ukena K, Tsutsui K: Expression and localization of cytochrome P45017 α-hydroxylase/c17,20 lyase in the avian brain. Brain Res 899: 112-122, 2001


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  13. Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami K, Sugiyama F, Goto K, Yanagisawa M, Sakurai T: Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron 38: 701-713, 2003


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’†•½@Œ’—S@ié‹Êˆã‰È‘åŠwEˆãŠw•”j
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“ç‘q@~ˆê@iŽ©‘R‰ÈŠwŒ¤‹†‹@\E¶—ŠwŒ¤‹†Šj
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  3. Rhee JS. Wang JM, Nabekura J, Inoue K, Akaike N: ATP facilitates spontaneous glycinergic IPSCs frequency at dissociated dorsal horn interneurone synapses. J Physiol 524: 471-483, 2000


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  5. Kakazu H, Uchida S, Nakagawa H, Akaike N, Nabekura J: Reversibility and ion selectivity of K+-Cl- cotransport in the CNS neurons. J Neurophysiol 84: 281-288, 2000


  6. Morishita H, Makishima T, Kaneko C, Lee YS, Segil N, Takahashi K, Kuraoka A, Nakagawa T, Nabekura J, Nakayama K, Nakayama KI: Deafness due to degeneration of cochlear neurons in caspase-3-deficient mice. Biochem Biophys Res Commun 284: 142-149, 2001


  7. Ueno T, Ueno S, Akaike N, Nabekura J: Bidirectional modulation of P2X receptor-mediated response by divalent cations in rat dorsal motor nucleus of the vagus. J Neurochem 78: 1009-1018, 2001


  8. Koyama S, Matsumoto N, Murakami N, Kubo C, Nabekura J, Akaike N: Role of presynaptic 5-HT1A and 5-HT3 receptors in modulation of synaptic GABA transmission in dissociated rat basolateral amygdala neurons. Life Sci 72: 375-387, 2002


  9. Uchida S, Noda E, Akaike N, Mizoguchi Y, Nabekura J: Allopregnanolone enhancement of GABAergic transmission in rat medial preoptic area neurons. Am J Physiol Endocrinol Metab 283: E1257-E1265, 2002


  10. Ueno T, Okabe A, Akaike A, Fukuda A, Nabekura J: Diversity of neuron-specific K+-Cl- cotransporter expression and inhibitory postsynaptic potential depression in rat motoneurons. J Biol Chem 277: 4945-4950, 2002


  11. Mizoguchi Y, Monji A, Nabekura J: Brain-derived neurotrophic factor induces long lasting Ca2+ activated K+ currents in rat visual cortex neurons. Eur J Neurosci 16: 1417-24, 2002


  12. Nabekura J, Ueno T, Okabe A, Furuta A, Iwaki T, Fukuda A, Shimizu-Okabe C, Akaike N: Gamma-amino butyric amino acid-induced excitation associated with reduction of KCC2 expression following in vivo axonal injury. J Neurosci 22: 4412-4417, 2002


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  18. Mizoguchi Y, Nabekura J: Sustained intracellular Ca2+ elevation induced by a brief BDNF application in rat visual cortex neurons. NeuroReport 14: 1481-1483, 2003


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  20. Moriguchi S, Mizoguchi Y, Tomimatsu Y, Hayashi Y, Kadowaki T, Kagamiishi Y, Katsube N, Yamamoto K, Inoue K, Watanabe S, Nabekura J, Nakanishi H: Potentiation of NMDA receptor-mediated synaptic responses by microglia. Mol Brain Res 119: 160-169, 2003


  21. Nabekura J, Katsurabayashi S, Kakazu Y, Shibata S, Matsubara A, Jinno S, Mizoguchi Y, Sasaki A, Ishibashi H: Developmental switch from GABA to glycine release in single central synaptic terminals. Nat Neurosci 7: 17-23, 2004


  22. Shibata S, Kakazu Y, Okabe A, Fukuda A, Nabekura J: Experience-dependent changes in intracellular Cl- regulation in developing auditory neurons. Neurosci Res 48: 211-220, 2004


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  6. Miyata M, Kim HT, Hashimoto K, Lee TK, Cho SY, Jiang H, Wu Y, Jun K, Wu D, Kano M, Shin HS: Deficient long-term synaptic depression in the rostral cerebellum correlated with impaired motor learning in phospholipase C beta4 mutant mice. Eur J Neurosci 13: 1945-1954, 2001


  7. Watase K, Weeber EJ, Xu B, Antalffy B, Yuva-Paylor L, Hashimoto K, Kano M, Atkinson R, Sun Y, Armstrong DL, Sweatt JD, Orr HT, Paylor R, Zoghbi HY: A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration. Neuron 34: 905-919, 2002


  8. Nishi M, Hashimoto K, Kuriyama K, Komazaki S, Kano M, Shibata S, Takeshima H: Motor discoordination in mutant mice lacking junctophilin type 3. Biochem Biophys Res Commun 292: 318-324, 2002


  9. Yoshida T, Hashimoto K, Zimmer A, Maejima T, Araishi K, Kano M: Endogenous cannabinoids mediate retrograde signal for depolarization-induced suppression of inhibition in cerebellar Purkinje cells. J Neurosci 22: 1690-1697, 2002


  10. Hashimoto K, Kano M: Functional differenciation of multiple climbing fiber inputs during synapse elimination in the developing cerebellum. Neuron 38: 785-796, 2003


  11. Takeda Y, Akasaka K, Lee S, Kobayashi S, Kawano H, Murayama S, Takahashi N, Hashimoto K, Kano M, Asano M, Sudo K, Iwakura Y, Watanabe K: Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup. J Neurobiol 56: 252-265, 2003


  12. Tabata T, Araishi K, Hashimoto K, Hashimotodani Y, van der Putten H, Bettler B, Kano M: Ca2+ activity at GABAB receptor constitutively promotes metabotropic glutamate signaling in the absence of GABA. Proc Natl Acad Sci USA 101: 16952-16957, 2004


  13. Miyazaki T, Hashimoto K, Shin HS, Kano M, Watanabe M: P/Q-type Ca2+ channel alpha1A regulates synaptic competition on developing cerebellar Purkinje cells. J Neurosci 24: 1734-1743, 2004


  14. Sato M, Tabata T, Hashimoto K, Nakamura K, Nakao K, Katsuki M, Kitano J, Moriyoshi K, Kano M, Nakanishi S: Altered agonist sensitivity and desensitization of neuronal mGluR1 responses in knock-in mice by a single amino acid substitution at the PKC phosphorylation site. Eur J Neurosci 20: 947-955, 2004


  15. Kitao Y, Hashimoto K, Matsuyama T, Iso H, Tamatani T, Hori O, Stern DM, Kano M, Ozawa K, Ogawa S: ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development. J Neurosci 24: 1486-1496, 2004


”©’†@Š°@i‘åã‘åŠwE’`”’Ž¿Œ¤‹†Šj
  1. Yamagishi S, Yamada M, Ishikawa Y, Matsumoto T, Ikeuchi T, Hatanaka H: p38 Mitogen-activated protein kinase regulates low potassium-induced apoptosis in cultured cerebellar granule neurons. J Biol Chem 276: 5129-5133, 2000


  2. Araki T, Yamada M, Ohnishi H, Sano S, Uetsuki T, Hatanaka H: Role of phosphatase activity of Shp-2 in BDNF signaling in cultured cerebral cortical neurons. J Neurochem 74: 659-668, 2000


  3. Nakayama H, Ueno S, Ikeuchi T, Hatanaka H: Regulation of α3 nicotinic acetylcholine receptor subunit mRNA levels by NGF and camp in PC12 cells. J Neurochem 74: 1346-1354, 2000


  4. Yoshikawa M, Nakayama H, Ueno S, Hirano M, Hatanaka H, Furuya H: Chronic fentanyl treatments induce the up-regulation of μ opioid receptor mRNA in rat pheochromocytoma cells. Brain Res 859: 217-223, 2000


  5. Numakawa T, Takei N, Hatanaka H: BDNF rapidly induces aspartate release from cultured CNS neurons. Neurosci Res 37: 59-65, 2000


  6. Inamura N, Araki T, Enokido Y, Nishio C, Aizawa S, Hatanaka H: The role of p53 in DNA stand break-induced apoptosis in organotypic slice cultures from the mouse cerebellum. J Neurosci Res 60: 450-457, 2000


  7. Takei N, Torres E, Yuhara A, Jongsma H, Otto C, Korhonen L, Abiru Y, Skoglosa Y, Schutz G, Hatanaka H, Sofroniew MV, Lindholm D: Pituitary adenylate cyclase-activating polypeptide promptes the survival of basal forebrain cholinergic neurons in vivo and in vitroFcomparison with effects of nerve growth factor. Eur J Neurosci 1: 2273-2280, 2000


  8. Ishikawa Y, Ikeuchi T, Hatanaka H: Brain-derived neurotrophic factor accelerates nitric oxide donor-induced apoptosis of cultured cortical neurons. J Neurochem 75: 494-502, 2000


  9. Satoh T, Furuta K, Tomokiyo K, Nakatsuka D, Tanikawa M, Nakanishi M, Miura M, Tanaka S, Koike T, Hatanaka H, Ikuta K, Suzuki M, Watanabe Y: Facilitatory rolews of mevel compounds designed from cyclopentenone prostaglanding on neurie outgrowth-promoting activities of nerve growth factor. J Neurochem 75: 1092-1102, 2000


  10. Araki T, Yamada M, Ohnishi H, Sano S, Hatanaka H: BIT/SHPS-1 enhances BDNF-promoted neuronal survival in cultured cerebral cortical neurons. J Neurochem 75: 1502-1510, 2000


  11. Nishio C, Yoshida K, Nishiyama K, Hatanaka H, Yamada M: Involvement of cystatin C in oxidative stress-induced apoptosis of cultured rat CNS neurons. Brain Res 873F252-262, 2000


  12. Yoshida K, Yamada M, Nishio C, Konishi A, Hatanaka H: SNRK, a member of th SNF1 family, is related to low K + -induced apoptosis of cultured rat cerebellar granule neurons. Brain Res 873: 274-282, 2000


  13. Satoh T, Furuta K, Tomokiyo K, Namura S, Nakatsuka D, Sugie Y, Ishikawa Y, Hatanaka H, Suzuki H, Watanabe Y: Neurotrophic actions of novel compounds designed from cyclopentenone prostaglandins. J Neurochem 77: 50-62, 2001


  14. Yuhara A, Nishio C, Abiru Y, Hatanaka H, Takei N: PACAP has a neurotrophic effect on cultured basal forebrain cholinergic neurons from adult rats. Dev Brain Res 131: 41-45, 2001


  15. Murai M, Enokido Y, Inamura N, Yoshino M, Nakatsu Y, van der Horst GT, Hoeijmakers JH, Tanaka K, Hatanaka H:  Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum group A and Cockayne syndrome group B DNA repair genes. Proc Natl Acad Sci USA 98: 13379-13384, 2001


  16. Kojima M, Takei N, Numakawa T, Ishikawa Y, Suzki S, Matsumoto T, Katoh-Semba R, Nawa H, Hatanaka H: Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neuritis of cultured hippocampal neurons. J Neurosci Res 64: 1-10, 2001


  17. Numakawa T, Matsumoto T, Adachi N, Yokomaku D, Kojima M, Takei N, Hatanaka H: Brain-derived neurotrophic factor triggers a rapid glutamate release through increase of intracellular Ca2+ and Na+ in cultured cerebellar neurons. J Neurosci Res 66: 96-108, 2001


  18. Yamada M, Suzuki K, Mizutani M, Asada A, Matozaki T, Ikeuchi T, Koizumi S, Hatanaka H: Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system. J Biochem 130: 157-165, 2001


  19. Inamura N, Enokido Y, Hatanaka H: Involvement of c-Jun N-terminal kinase and caspase 3-like protease in DNA damage-induced, p53-mediated apoptosis of cultured mouse cerebellar granule neurons. Brain Res 904: 270-278, 2001


  20. Satoh T, Furuta K, Tomokiyo K, Namura S, Nakatsuka D, Sugie Y, Ishikawa Y, Hatanaka H, Suzuki M, Watanabe Y: Neurotrophic actions of novel compounds designed from cyclopentenone prostaglandins. J Neurochem 77: 50-62, 2001


  21. Yamagishi S, Yamada M, Ishikawa Y, Matsumoto T, Ikeuchi T, Hatanaka H: p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons. J Biol Chem 276: 5129-5133, 2001


  22. Yamada M, Tanabe K, Wada K, Shimoke K, Ishikawa Y, Ikeuchi T, Koizumi S, Hatanaka H: Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons. J Neurochem 78: 940-951, 2001


  23. Matsumoto T, Numakawa T, Adachi N, Yokomaku D, Yamagishi S, Takei N, Hatanaka H: Brain-derived neurotrophic factor enhances depolarization-evoked glutamate release in cultured cortical neurons. J Neurochem 79: 522-530, 2001


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  1. Yamano M, Ogura H, Okuyama S, Ohki-Hamazaki H: Modulation of 5-HT system in mice with a targeted disruption of neuromedin B receptor. J Neurosci Res 68: 59-64, 2002


  2. Iwabuchi M, Ui-Tei K, Yamada K, Matsuda Y, Sakai Y, Tanaka K, Ohki-Hamazaki H: Molecular cloning and characterization of avian bombesin-like peptide receptorsFnew tools for investigating molecular basis for ligand selectivity. Br J Pharmacol 139: 555-566, 2003


  3. Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K: Short-interfering-RNA-mediated gene silencing in mammalian cells requires dicer and elF2C translation initiation factors. Curr Biol 13: 41-46, 2003


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  1. Hayashi M, Mitsunaga F, Itoh M, Shimizu K, Yamashita A: Development of full-length Trk B-immunoreactive structures in the prefrontal and visual cortices of the macaque monkey. Anat Embryol 201: 139-147, 2000


  2. Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M: Expression of GAP-43 and SCG10 mRNAs in lateral geniculate nucleus of normal and monocularly deprived macaque monkeys. J Neurosci 20: 6030-6038, 2000


  3. Kimura K, Shimizu K, Hayashi M, Ishikawa T, Ago Y: Pituitary-adrenocortical responses to the first dyadic encounters in male rhesus monkeys: Effect of dominance relationship. Am J Primatol 50: 247-256, 2000


  4. Hayashi M, Mitsunaga F, Ohira K, Shimizu K: Changes in BDNF-immunoreactive structures in the hippocampal formation of the aged macaque monkey. Brain Res 918: 191-196, 2001


  5. Hayashi M, Ito M, Shimizu K: The spindle neurons are present in the cingulate cortex of chimpanzee fetus. Neurosci Lett 309: 97-100, 2001


  6. Ohira K, Shimizu K, Hayashi M: TrkB dimerization during development of the prefrontal cortex of the macaque. J Neurosci Res 65: 463-469, 2001


  7. Watakabe A, Fujita H, Hayashi M, Yamamori T: Growth/differentiation factor 7 is preferentially expressed in the primary motor area of the monkey neocortex. J Neurochem 76: 1455-1464, 2001


  8. Tohno S, Tohno Y, Hayashi M, Moriwake Y, Minami T, Nishiwaki F, Araki T: Accumulation of calcium in the arteries of Japanese monkey. Biol Trace Elem Res 82: 77-86, 2001


  9. Tohno S, Tohno Y, Hayashi M, Moriwake Y, Minami T: Accumulation of magnesium as well as calcium and phosphorus in Japanese monkey arteries with aging. Biol Trace Elem Res 84: 81-92, 2001


  10. Oishi T, Higo N, Matsuda K, Hayashi M: Expression of superior cervical ganglion-10(SCG) mRNA in the monkey cerebral cortex during postnatal development. Neurosci Lett 323: 199-202, 2002


  11. Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M: Expression of MARCKS mRNA in lateral geniculate nucleus and visual cortex of normal and monocularly deprived macaque monkeys. Vis Neurosci 19: 633-643, 2002


  12. Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M: Northern blot and in situ hybridization analysis of MARCKS mRNA expression in the cerebral cortex of the macaque monkey. Cereb Cortex 12: 552-564, 2002


  13. Mori T, Yamashita D, Homma K, Shimizu K, Hayashi M: Changes in NT-3 and TrkC in the primary visual cortex of developing macaques. NeuroReport 13: 1689-1694, 2002


  14. Mori T, Shimizu K, Hayashi M: Levels of serum brain-derived neurotrophic factor in primates. Primates 44: 167-169, 2003


  15. Ohira K, Hayashi M: Expression of TrkB subtypes in the adult monkey cerebellar cortex. J Chem Neuroanat 25: 175-183, 2003


  16. Shimizu K, Douke C, Fujita S, Matsuzawa T, Tomonaga M, Tanaka M, Matsubayashi K, Hayashi M: Urinary steroids, FSH and CG measurements for monitoring the ovarian cycle and pregnancy in the chimpanzee. J Med Primatol 32: 15-22, 2003


  17. Itoh M, Kondo M, Kojima C, Jin W, Watanabe G, Taya K, Hayashi M, Shimizu K: Inhibin B is the major form of inhibibin secreted from testes in male Japanese macaques (Macaca fuscata). Primates 44: 253-257, 2003


  18. Shimizu K, Udono T, Tanaka C, Narushima E, Yoshihara M, Takeda M, Tanahashi A, van Elsacker L, Hayashi M, Takenaka O: Comparative study of urinary reproductive hormones in great apes. Primates 44: 183-190, 2003


  19. Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M: Cell type- and region-specific expression of protein kinase C-substrate mRNAs in the cerebellum of the macaque monkey. J Comp Neurol 467: 135-149, 2003


  20. Tohno S, Tohno Y, Hayashi M, Minami T, Moriwake Y, Azuma C, Ohnishi Y: Comparison of mineral contents between the arteries in upper and lower limbs of Japanese monkeys. Biol Trace Elem Res 95: 173-184, 2003


  21. Higo N, Oishi T, Yamashita K, Matsuda K, Hayashi M: Cell type- and region-specific expression of neurogranin mRNA in the cerebral cortex of the macaque monkey. Cereb Cortex14: 1154-1143, 2004


  22. Ohira K, Funatsu N, Nakamura S, Hayashi M: Expression of BDNF and TrkB receptor subtypes in the postnatal developing Purkinje cells of monkey cerebellum. Gene Expr Patterns 4: 257-261, 2004


  23. Mori T, Shimizu K, Hayashi M: Differential expression patterns of TrkB ligands in the macaque monkey brain. NeuroReport 15: 2507-2511, 2004


  24. Higo N, Oishi T, Yamashita A, Murata Y, Matsuda K, Hayashi M: Northern blot and in situ hybridization analyses for the development of myristoylated alanine-rich c-kinase substrate mRNA in the monkey cerebral cortex. Neuroscience 129: 167-177, 2004


  25. Ohira K, Kumanogoh H, Sahara Y, Homma KJ, Hirai H, Nakamura S, Hayashi M: A truncated tropomyosin-related kinase B, T1, regulates glial cell morphology via Rho GDP dissociation inhibitor I. J Neurosci 25: 1343-1353, 2005


žwŽR@•Žj@iŽ©‘R‰ÈŠwŒ¤‹†‹@\AŠî‘b¶•¨ŠwŒ¤‹†Šj
  1. Hiyama TY, Watanabe E, Okado H, Noda M: The subfornical organ is the primary locus of sodium-level sensing by Nax sodium channels for the control of salt-intake behavior. J Neurosci 24: 9276-9278, 2004


  2. Kiyosue K, Hiyama TY, Nakayama K, Kasai M, Taguchi T: Re-expression of NR2B-containing NMDA receptors in vitro by suppression of neuronal activity. Int J Dev Neurosci 22: 59-65, 2004


  3. Noda M, Hiyama TY: Sodium-level-sensitive sodium channel and salt-intake-behavior. Chem Senses 30 Suppl 1: i44-i45, 2005


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  1. Yamada Y, Fukuda A, Tanaka M, Shimano Y, Nishino H, Muramatsu K, Togari H, Wada Y: Immature stage of intracellular Cl- homeostasis regulated by cation-Cl- cotransporters in rat neocortical neurons. Nagoya Med J 43: 179-190, 2000


  2. Samejima M, Shavali S, Tamotsu S, Uchida K, Morita Y, Fukuda A: Light- and temperature-dependence of the melatonin secretion rhythm in the pineal organ of the lamprey, Lampetra japonica. Jpn J Phyisiol 50: 437-442, 2000


  3. Kanaka C, Ohno K, Okabe A, Kuriyama K, Itoh T, Fukuda A, Sato K: The differential expression patterns of messenger RNAs encoding K-Cl cotransporters (KCC1,2) and Na-K-2Cl cotransporter (NKCC1) in the rat nervous system. Neuroscience 104: 933-946, 2001


  4. Yamada Y, Fukuda A, Tanaka M, Shimano Y, Nishino H, Muramatsu K, Togari H, Wada Y: Optical imaging reveals cation-Cl- cotransporter-mediated transient rapid decrease in intracellular Cl- concentration induced by oxygen-glucose deprivation in immature rat neocortical slices. Neurosci Res 39: 269-280, 2001


  5. Farkas I, Baranyi L, Ishikawa Y, Okada N, Bohata C, Budai D, Fukuda. A, Imai M, Okada H: CD59 blocks not only the insertion of C9 into MAC but inhibits ion channel formation of homologous C5b-8 as well as C5b-9. J Physiol 539: 537-545, 2002


  6. Ueno T, Okabe A, Akaike N, Fukuda A, Nabekura J: Diversity of neuron-specific K+-Cl- cotransporter expression and inhibitory postsynaptic potential depression in rat motoneurons. J Biol Chem 277: 4945-4950, 2002


  7. Nabekura J, Ueno T, Okabe A, Furuta A, Iwaki T, Shimizu-Okabe C, Fukuda A, Akaike N: Reduction of KCC2 expression and GABAA receptor-mediated excitation after in vivo axonal injury. J Neurosci 22: 4412-4417, 2002


  8. Kilb W, Ikeda M, Uchida K, Okabe A, Fukuda A, Luhmann HJ: Depolarizing glycine responses in Cajal-Retzius cells of neonatal rat cerebral cortex. Neuroscience 112: 299-307, 2002


  9. Mikawa S, Wang C, Shu F, Wang T, Fukuda A, Sato K: Developmental changes in KCC1, KCC2, and NKCC1 mRNAs in the rat cerebellum. Dev Brain Res 136: 93-100, 2002


  10. Okabe A, Ohno, K, Toyoda H, Yokokura M, Sato K, Fukuda A: Amygdala kindling induces upregulation of mRNA for NKCC1, a Na+,K+,-2Cl- cotransporter, in the rat piriform cortex. Neurosci Res 44: 225-229, 2002


  11. Wang C, Shimizu-Okabe C, Watanabe K, Okabe A, Matsuzaki H, Ogawa T, Mori N, Fukuda A, Sato K: Developmental Changes in KCC1, KCC2, and NKCC1 mRNA expressions in the rat brain. Dev Brain Res 139: 59-66, 2002


  12. Shimizu-Okabe C, Yokokura M, Okabe A, Ikeda M, Sato K, Kilb W, Luhmann HJ, Fukuda A: Layer-specific expression of Cl- transporters and differential [Cl-]i in newborn rat cortex. NeuroReport 13: 2433-2437, 2002


  13. Toyoda H, Ohno K, Okabe A, Ikeda M, Yamada J, Sato K, Hashimoto K, Fukuda A: Induction of NMDA and GABAA receptors-mediated Ca2+ oscillations with KCC2 mRNA downregulation in injured facial motoneurons. J Neurophysiol 89: 1353-1362, 2003


  14. Farkas I, Takahashi M, Fukuda A, Yamamoto N, Akatsu H, Baranyi L, Tateyama H, Yamamoto T, Okada N, Okada H: Complement C5a receptor-mediated signalling may be involved in neurodegeneration in Alzheimerfs disease. J Immunol 170: 5764-5771, 2003


  15. Isomura Y, Sugimoto M, Fujiwara-Tsukamoto Y, Yamamoto-Muraki S, Yamada J, Fukuda A: Synaptically activated Cl- accumulation responsible for depolarizing GABAergic responses in mature hippocampal neurons. J Neurophysiol 90: 2752-2756, 2003


  16. Ikeda M, Toyoda H, Yamada J, Okabe A, Sato K, Hotta Y, Fukuda A: Differential development of cation-chloride cotransporters and Cl- homeostasis contributes to differential GABAergic actions between developing rat visual cortex and dorsal lateral geniculate nucleus. Brain Res. 984: 149-159, 2003


  17. Okabe A, Yokokura M, Toyoda H, Shimizu-Okabe C, Ohno K, Sato K, Fukuda A: Changes in chloride homeostasis-regulating gene expressions in the rat hippocampus following amygdala kindling. Brain Res 990: 221-226, 2003


  18. Takeuchi K, Fukuda A, Kanayama N: Effect of urinary trypsin inhibitor on potassium currents: fetus modulates membrane excitability by production of UTI. ActaObstet Gynecol Scand 83: 6-11, 2004


  19. Okabe A, Kilb W, Shimizu-Okabe C, Hanganu IL, Fukuda A, Luhmann HJ: Homogenous glycine receptor expression in cortical plate neurons and Cajal-Retzius cells of neonatal rat cerebral cortex. Neuroscience123: 715-724, 2004


  20. Nakanishi K, Watanabe K, Kawabata M, Fukuda A, Oohira A: Altered synaptic activities in cultures of neocortical neurons from prenatally X-irradiated rats. Neurosci Lett 355: 61-64, 2004


  21. Ikeda K, Onimaru H, Yamada J, Inoue K, Ueno S, Onaka T, Toyoda H, Arata A, Ishikawa TO, Taketo MM, Fukuda A, Kawakami K: Malfunction of respiratory-related neuronal activity in Na+, K+-ATPase alpha2 subunit-deficient mice is attributable to abnormal Cl- homeostasis in brainstem neurons. J Neurosci 24: 10693-10701, 2004


  22. Shibata S, Kakazu Y, Okabe A, Fukuda A, Nabekura J: Experience-dependent changes in intracellular Cl- regulation in developing auditory neurons. Neurosci Res 48: 211-220, 2004


  23. Inoue K, Ueno S, Fukuda A: Interaction of neuron-specific K+-Cl- cotransporter, KCC2, with brain-type creatine kinase. FEBS Lett 564: 131-135, 2004


  24. Uchida K, Samejima M, Okabe A, Fukuda A: Neuroprotective effects of melatonin against anoxia/aglycemia stress, as assessed by synaptic potentials and superoxideproduction in rat hippocampal slices. J Pineal Res 37: 215-222, 2004


  25. Yamada J, Okabe A, Toyoda H, Kilb W, Luhmann H. J, Fukuda A: Cl- uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1. J Physiol 557: 829-841, 2004


  26. Toyoda H, Yamada J, Ueno S, Okabe A, Kato H, Sato K, Hashimoto K, Fukuda A: Differential functional expression of cation-Cl- cotransporter mRNAs (KCC1, KCC2, and NKCC1) in rat trigeminal nervous system. Mol Brain Res. 133: 12-18, 2005


  27. Ueta Y, Fujihara H, Serino R, Dayanithi G, Ozawa H, Matsuda K, Kawata M, Yamada J, Ueno S, Fukuda A, Murphy D: Transgenic expression of enhanced green fluorescent protein enables direct visualization for physiological studies of vasopressin neurons and isolated nerve terminals of the rat. Endocrinology 146: 406-413, 2005


  28. Inoue K, Ueno S, Yamada J, Fukuda A: Characterization of newly cloned variant of rat glycine receptor α1 subunit. Biochem Biophys Res Commun 327: 300-305, 2005


  29. Wang C, Ohno K, Furukawa T, Ueki T, Ikeda M, Fukuda A Sato K: Differential expression of KCC2 accounts for the differential GABA responses between relay and intrinsic neurons in the early postnatal rat olfactory bulb. Eur J Neurosci 21: 1449-1455, 2005


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  1. Oka M, Wada M, Yamamoto A, Itoh Y, Fujita T: Functional expression of constitutive nitric oxide synthases regulated by voltage gated Na+- and Ca2+ channels in cultured human astrocytes. Glia 46: 53-62, 2004


  2. Tanaka K, Yamamoto A, Fujita T: Functional expression and adaptive regulation of Na+-dependent neutral amino acid transporter SNAT2/ATA2 in normal human astrocytes under amino acid starved conditions. Neurosci Lett 378: 70-75, 2005


  3. Uchiyama T, Matsuda Y, Wada M, Takahashi S, Fujita T: Functional regulation of Na+-dependent neutral amino acid transporter ASCT2 by S-nitrosothiols and nitric oxide in Caco-2 cells. FEBS Lett 579: 2499-2506, 2005


  4. Fujita T, Katsukawa H, Yodoya E, Wada M, Shimada A, Okada N, Yamamoto A, Fujita T: Transport characteristics of N-acetyl-l-aspartate in rat astrocytes: involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system. J Neurochem93: 706-714, 2005


  5. Wada M, Miyakawa S, Shimada A, Okada N, Yamamoto A, Fujita T: Functional linkage of H+/peptide transporter PEPT2 and Na+/H+ exchanger in primary cultures of astrocytes from mouse cerebral cortex. Brain Res 1044: 33-41, 2005


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  1. Momiyama T: Parallel decrease in ω-conotoxin-sensitive transmission and dopamine-induced inhibition at the striatal synapse of developing rats. J Physiol 546: 483-490, 2003


  2. Kaifu T, Nakahara J, Inui M, Mishima K, Momiyama T, Kaji M, Sugahara A, Koito H, Asai-Ujike A, Nakamura A, Kanazawa K, Tan-Takeuchi K, Iwasaki K, Yokoyama WM, Kudo A, Fujiwara M, Asou H, Takai T: Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice. J Clin Invest 111: 323-332, 2003


  3. Uchida K, Momiyama T, Okano H, Yuzaki M, Koizumi A, Mine Y, Kawase T: Potential functional neural repair with grafted neural stem cells of early embryonic neuroepithelial origin. Neurosci Res 52: 276-286, 2005


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  1. Morimoto R, Hayashi M, Yatsushiro S, Otsuka M, Yamamoto A, Moriyama Y: Co-expression of vesicular glutamate transporters (VGLUT1 and VGLUT2) and their association with synaptic-like microvesicles in rat pinealocytes. J Neurochem 84: 382-391, 2003


  2. Hayashi M, Yamada H, Uehara S, Morimoto R, Muroyama A, Takeda J, Yamamoto A, Moriyama Y: Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers a glutamatergic signal transmisson in islets of Langerhans. J Biol Chem 278: 1966-1974, 2003


  3. Kinuta M, Kinuta K, Yamada H, Abe T, Yoshida Y, Araki K, Li SA, Otsuka A, Nakanishi A, Moriyama Y, Takei K: Formation of S-(2-carboxy-1-(1H-imidazol-4-yl) ethyl)glutathione, a new metabolite of L-histidine, from cis-urocanic acid and glutathione by the action of glutathione S-transferase. Electrophoresis 24: 3212-3218, 2003


  4. Hayashi M, Otsuka M, Morimoto R, Muroyama A, Uehara S, Yamamoto A, Moriyama Y: Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in αTC6 cells, mouse clonal α cells, and α cells of islets of Langerhans. Diabetes 52: 2066-2074, 2003


  5. Taraschi TF, OfDonnell M, Martinez S, Schneider T, Trelka D, Tilley L, Moriyama Y: Generation of an erythrocyte protein secretory system by Plasmodium falciparum Malaria parasites. Blood 102: 3420-3426, 2003


  6. Hayashi M, Morimoto R, Yamamoto A, Moriyama Y: Expression and localization of vesicular glutamate transporters in pancreatic islets, upper gastrointestinal tract, and testis. J Histochem Cytochem 51: 1375-1390, 2003


  7. Wang H, Ichihara G, Ito H, Kato K, Kitoh J, Yamada T, Yu X, Tsuboi S, Moriyama Y, Takeuchi Y: Dose-dependent biochemical changes in rat central nervous system after 12-week exposure to 1-bromopropane. Neurotoxicology 24: 199-206, 2003


  8. Anno T, Uehara S, Katagiri H, Ohta Y, Ueda K, Mizuguchi H, Moriyama Y, Oka Y, Tanizawa Y: Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation. Am J Physiol Endocrinol Metab 286: E280-E285, 2004


  9. Uehara S, Muroyama A, Echigo N, Morimoto R, Otsuka M, Yatsushiro S, Moriyama Y: Metabotropic glutamate receptor type 4 is involved in auto-inhibitory cascade for glucagon secretion by a cells of islet of Langerhans. Diabetes 53: 998-1006, 2004


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ŽR“c@‰ëŽi@i‘åã‘åŠwE’`”’Ž¿Œ¤‹†Šj
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—Mè@’ʉî@iŒcœä‹`m‘åŠwEˆãŠw•”j
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“n粁@‹±—ǁ@i‘åãŽs—§‘åŠwE‘åŠw‰@ˆãŠwŒ¤‹†‰Èj
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  2. Cao C, Matsumura K, Shirakawa N, Maeda M, Jikihara I, Kobayashi S, Watanabe Y: Pyrogenic cytokines injected into the rat cerebral ventricle induce cyclooxygenase-2 in brain endothelial cells and also upregulate their receptors. Eur J Neurosci 13: 1781-1790, 2001


  3. Nakadate K, Imamura K, Watanabe Y: Effects of monocular deprivation on the expression pattern of alpha-1 and beta-1 adrenergic receptors in the kitten visual cortex. Neurosci Res 40: 155-162, 2001


  4. Sihver S, Marklund N, Hillered L, Långström B, Watanabe Y, Bergström M: Changes in mACh, NMDA, and GABAA receptor binding after lateral fluid-percussion injury: in vitro autoradiography of rat brain frozen sections. J Neurochem 78: 417-423, 2001


  5. Frykholm P, Hillered L, Långström B, Persson L, Valtysson J, Watanabe Y, Enblad P: Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model. J Neurol Neurosurg Psychiat 71: 455-461, 2001


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