ŽO•i@¹”ü@i“Œ‹ž‘åŠwE‘åŠw‰@ˆãŠwŒnŒ¤‹†‰Èj
- Inoue M, Mishina M, Ueda H: Enhanced nociception by exogenous and
endogenous substance P given into the spinal cord in mice lacking
NR2A/ε1, an NMDA receptor subunit. Br J Pharmacol 129:
239-241, 2000
- Ito I, Kawakami R, Sakimura K, Mishina M, Sugiyama H: Input-specific
targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal
neuron synapses. Neuropharmacology 39: 943-951, 2000
- Minami T, Okuda-Ashitaka E, Mori H, Sakimura K, Watanabe M, Mishina
M, Ito S: Characterization of nociceptin/orphanin FG-induced pain
responses in conscious mice: Neonatal capsaicin treatment and N-methyl-D-aspartate
receptor GluRε subunit knockout mice. Neuroscience 97:
133-142, 2000
- Hironaka K, Umemori H, Tezuka T, Mishina M, Yamamoto T: The protein-tyrosine
phosphatase PTPMEG interacts with glutamate receptor δ2 and εsubunits.
J Biol Chem 275: 16167-16173, 2000
- Matsuda I, Mishina M: Identification of a juxtamembrane segment
of the glutamate receptor δ2 subunit required for the plasma
membrane localization. Biochem Biophys Res Commun 275: 565-571,
2000
- Nakamura K, Manabe, T, Watanabe M, Mamiya T, Ichikawa R, Kiyama
Y, Sanbo M, Yagi T, Inoue Y, Nabeshima T, Mori H, Mishina M: Enhancement
of hippocampal LTP, reference memory and sensorimotor gating in mutant
mice lacking a telencephalon-specific cell adhesion molecule. Eur
J Neurosci 13: 179-189, 2001
- Nakazawa T, Komai S, Tezuka T, Hisatsune C, Umemori H, Semba K,
Mishina M, Manabe T, Yamamoto T: Characterization of Fyn-mediated
tyrosine phosphorylation sites on GluRε2 (NR2B) subunit of the
N-methyl-D-aspartate receptor. J Biol Chem 276: 693-699,
2001
- Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T: Hyperfunction
of dopaminergic and serotonergic neural systems in mice lacking NMDA
receptor ε1 subunit. J Neurosci 21: 750-757, 2001
- Uchino S, Nakamura T, Nakamura K, Nakajima-Iijima S, Mishina M,
Kohsaka S, Kudo Y: Real-time two-dimensional visualization of ischemia-induced
glutamate release from hippocampal slices. Eur J Neurosci 13:
670-678, 2001
- Kishimoto Y, Kawahara S,Mori H,Mishina M, Kirino Y: Long-trace interval
eyeblink conditioning is impaired in mutant mice lacking the NMDA
receptor subunit ε1. Eur J Neurosci 13: 1221-1227, 2001
- Kishimoto Y, Kawahara S, Suzuki M, Mori H, Mishina M, Kirino Y:
Classical eyeblink conditioning in glutamate receptor subunit ε2
mutant mice is impaired in the delay paradigm but not in the trace
paradigm. Eur J Neurosci 13: 1249-1253, 2001
- Kitayama K, Abe M, Kakizaki T, Honma D, Natsume R, Fukaya M, Watanabe
M, Miyazaki J, Mishina M, Sakimura K: Purkinje cell-specific and inducible
gene recombination system generated from C57BL/6 mouse ES cells. Biochem
Biophys Res Commun 281: 1134-1140, 2001
- Minami T, Matsumura S, Okuda-Ashitaka E, Shimamoto K, Sakimura K,
Mishina M, Mori H, Ito S: Characterization of the glutamatergic system
for induction and maintenance of allodynia. Brain Res 895:
178-185, 2001
- Takeuchi T, Kiyama Y, Nakamura K, Tsujita M, Matsuda I, Mori H,
Munemoto Y, Kuriyama H, Natsume R, Sakimura K, Mishina M: Roles of
the glutamate receptor ε2 and δ2 subunits in the potentiation
and prepulse inhibition of the acoustic startle reflex. Eur J Neurosci
14: 153-160, 2001
- Wainai T, Takeuchi T, Seo N, Mishina M: Regulation of acute nociceptive
responses by the NMDA receptor GluRε2 subunit. NeuroReport
12: 3165-3172, 2001
- Uchino S, Watanabe W, Nakamura T, Shuto S, Kazuta Y, Matsuda A,
Nakajima-Iijima S, Kohsaka S, Kudo Y, Mishina M: Establishment of
CHO cell lines expressing four N-methyl-D-aspartate receptor
subtypes and characterization of subtype selectivity of a novel antagonist
PPDC. FEBS Lett 506: 117-122, 2001
- Kishimoto Y, Kawahara S, Fujimichi R, Mori H, Mishina M, Kirino
Y: Impairment of eyeblink conditioning in GluRε2 mutant mice
depends on the temporal overlap between conditioned and unconditioned
stimuli. Eur J Neurosci 14: 1515-1521, 2001
- Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K,
Mishina M, Hashikawa T, Konnerth A, Watanabe M, Kano M: Roles of GluRε2
and mGluR1 in climbing fiber synapse elimination during postnatal
cerebellar development. J Neurosci 21: 9701-9712, 2001
- Takatsuki K, Kawahara S, Mori H, Mishina M, Kirino Y: Scopolamine
impairs eyeblink conditioning in the cerebellar LTD-deficient mice.
NeuroReport 13: 159-162, 2002
- Miyagi Y, Yamashita T, Fukaya M, Sonoda T, Okuno T, Yamada K, Watanabe
M, Nagashima Y, Aoki I, Okuda K, Mishina M, Kawamoto S: Delphilin:
a novel PDZ- and formin homology-domain containing protein, which
synaptically colocalizes and interacts with glutamate receptor ε2
subunit. J Neurosci 22: 803-814, 2002
- Haradahira T, Okauchi T, Maeda J, Zhang M-R, Kida T, Kawabe K, Mishina
M, Watanabe Y, Suzuki K, Suhara T: A positron-emitter labeled glycineB
site antagonist, [11C]L-703,717, preferentially binds to
a cerebellar NMDA receptor subtype consisting of GluRε3 subunits
in vivo, but not in vitro. Synapse 43: 131-133,
2002
- Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T: Lower
sensitivity to stress and altered monoaminergic neuronal function
in mice lacking the NMDA receptor ε4 subunit. J Neurosci
22: 2335-2342, 2002
- Takeuchi T, Nomura T, Tsujita M, Suzuki M, Fuse T, Mori H, Mishina
M: Flp recombinase transgenic mice of C57BL/6 strain for conditional
gene targeting. Biochem Biophys Res Commun 293: 953-957, 2002
- Sakamoto T, Mishina M, Niki H: Mutation of NMDA receptor subunit
epsilon 1: Effects on audiogenic-like seizures induced by electrical
stimulation of the inferior coliculus in mice. Mol Brain Res
102: 113-117, 2002
- Uemura T, Mori H, Mishina M: Isolation and characterization of Golgi
apparatus-specific GODZ with the DHHC zinc finger domain. Biochem
Biophys Res Commun 296: 492-496, 2002
- Ichikawa R, Miyazaki T, Kano M, Hashikawa T, Tatsumi H, Sakimura
K, Mishina M, Inoue Y, Watanabe M: Distal extension of climbing fiber
territory and multiple innervation caused by aberrant wiring to adjacent
spiny branchlets in cerebellar Purkinje cells lacking glutamate receptor
GluRδ2. J Neurosci 22: 8487-8503, 2002
- Takatsuki K, Kawahara S, Kotani S, Mori H, Mishina M, Kirino Y:
Hippocampal damage disrupts eyeblink conditioning in mice lacking
glutamate receptor δ2. J Biol Phys 28: 539-547, 2002
- Takatsuki K, Kawahara S, Kotani S, Fukunaga S, Mori H, Mishina M,
Kirino Y: The hippocampus plays an important role in eyeblink conditioning
with a short trace interval in glutamate receptor subunit δ2
mutant mice. J Neurosci 23, 17-22, 2003
- Townsend M, Yoshii A, Mishina M, Constantine-Paton M: Developmental
loss of miniature N-methyl-D-aspartate receptor currents in
NR2A knockout mice. Proc Natl Acad Sci USA 100: 1340-1345,
2003
- Fagiolini M, Katagiri H, Miyamoto H, Grant SGN, Mishina M, Hensch
T: Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate
receptor 2A signaling. Proc Natl Acad Sci USA 100: 2854-2859,
2003
- Brickley SG, Misra C, Mok MHS, Mishina M, Cull-Candy SG: NR2B and
NR2D subunits co-assemble in cerebellar Golgi cells to form a distinct
NMDAR subtype restricted to extrasynaptic sites. J Neurosci
23: 4958-4966, 2003
- Okada H, Miyakawa N, Mori H, Mishina M, Miyamoto Y, Hisatsune T:
NMDA receptors in cortical development are essential for the generation
of coordinated increase in [Ca2+]i in eneuronal
domainsf. Cereb Cortex 13: 749-757, 2003
- Inoue M Mishina, M, Ueda H: Locus-specific rescue of GluRe1 NMDA
receptors in mutant mice identifies the brain regions important for
morphine tolerance and dependence. J Neurosci 23: 6529-6536,
2003
- Kitayama T, Mishina M, Sugiyama H: Enhancement of neurogenesis by
running wheel exercises is suppressed in mice lacking NMDA receptor
ε1 subunit. Neurosci Res 47: 55-63, 2003
- Mori H, Mishina M: Roles of diverse glutamate receptors in brain
functions elucidated by subunit-specific and region-specific gene
targeting. Life Sci 74, 329-336, 2003
- Takahashi Y, Mori H, Mishina M, Watanabe M, Fujiwara T, Shimomura
J, Aiba H, Miyajima T, Saito Y, Nezu A, Nishida H, Imai K, Sakaguchi
N, Kondo N: Autoantibodies to NMDA receptor in patients with chronic
forms of epilepsia partialis continua. Neurology 61: 891-896,
2003
- Kitano T, Matsumura S, Seki T, Hikida T, Sakimura K, Nagano T, Mishina
M, Nakanishi S, Ito S: Characterization of N-methyl-D-aspartate
receptor subunits involved in acute ammonia toxicity. Neurochem
Int 44: 83-90, 2004
- Miyamoto Y, Yamada K, Nagai T, Mori H, Mishina M, Furukawa H, Noda
Y, Nabeshima T: Behavioral adaptations to addictive drugs in mice
lacking the NMDA receptorε1 subunit. Eur J Neurosci 19,
151-158, 2004
- Murai N, Tsuji J, Ito J, Mishina M Hirano T: Vestibular compensation
in glutamate receptor delta-2 subunit knockout mice: dynamic property
of vestibulo-ocular reflex. Eur Arch Oto-Rhino-Laryngol 261:
82-86, 2004
- Yoshida T, Katoh A, Ohtsuki G, Mishina M, Hirano T: Oscillating
Purkinje neuron activity causing involuntary movement in a mutant
mouse deficient in the glutamate receptor δ2 subunit. J Neurosci
24: 2440-2448, 2004
- Uemura T, Mori H, Mishina M: Direct interaction of GluRδ2 with
Shank scaffold proteins in cerebellar Purkinje cells. Mol Cell
Neurosci 26: 330-341, 2004
- Fuse T, Kanai Y, Kanai-Azuma M, Suzuki M, Nakamura K, Mori H, Hayashi,
Y, Mishina, M: Conditional activation of RhoA suppresses the epithelial
to mesenchymal transition at the primitive streak during mouse gastrulation.
Biochem Biophys Res Commun 318: 665-672, 2004
- Sato Y, Kobayashi E, Hakamata Y, Kobahashi M, Wainai T, Murayama
T, Mishina M, Seo N: Chronopharmacological studies of ketamine in
normal and NMDA ε1 receptor knockout mice. Br J Anaesth
92: 859-864, 2004
- Takehara K, Kawahara S, Munemoto Y, Kuriyama H, Mori H, Mishina
M, Kirino Y: The NMDA receptor GluRε2 is important for delay
and trace eyeblink conditioning in mice. Neurosci Lett 364:
43-47, 2004
- Abe M, Fukaya M, Yagi T, Mishina M, Watanabe M, Sakimura K: NMDA
receptor GluRε/NR2 subunits are essential for postsynaptic localization
and protein stability of GluRζ1/NR1 subunit. J Neurosci
24: 9292-9304, 2004
- Nishimura W, Muratani T, Tatsumi S, Sakimura K, Mishina M, Minami
T, Ito S: Characterization of N-methyl-D-aspartate receptor
subunits responsible for postoperative pain. Eur J Pharmacol
503: 71-75, 2004
- Ohtsuki G, Kawaguchi S, Mishina M, Hirano T: Enhanced inhibitory
synaptic transmission in the cerebellar molecular layer of the GluRδ2
knockout mouse. J Neurosci 24: 10900-10907, 2004
- Takeuchi, T, Miyazaki T, Watanabe M, Mori H, Sakimura K, Mishina
M: Control of synaptic connection by glutamate receptor δ2 in
the adult cerebellum. J Neurosci 25: 2146-2156, 2005
- Sakamoto T, Takatsuki K, Kawahara S, Kirino Y, Niki H, Mishina M:
Role of hippocampal NMDA receptors in trace eyeblink conditioning.
Brain Res 1039: 130-136, 2005
- Hirai H, Miyazaki T, Kakegawa W, Matsuda S, Mishina M, Watanabe
M, Yuzaki M: Rescue of abnormal phenotypes of the δ2 glutamate
receptor-null mice by mutant δ2 transgenes. EMBO Rep 6:
90-95, 2005
•½–ì@ä•v@i‹ž“s‘åŠwE‘åŠw‰@—ŠwŒ¤‹†‰Èj
- Kawaguchi S, Hirano T: Suppression of inhibitory synaptic potentiation
by presynaptic activity through postsynaptic GABAB receptors
in a Purkinje neuron. Neuron 27: 339-347, 2000
- Imamura Y, Inokawa H, Ito A, Kadotani H, Toyama K, Noda S, Nakanishi
S, Hirano T: Roles of GABAergic inhibition and NMDA receptor subunits
in the spatio-temporal integration in the cerebellar cortex of mice.
Neurosci Res 38: 289-301, 2000
- Okano H, Hirano T, Balaban E: Learning and memory. Proc Natl
Acad Sci USA 97: 12403-12404, 2000
- Iwashita M, Kanai R, Funabiki K, Matsuda K, Hirano T: Dynamic properties,
interactions and adaptive modifications of vestibulo-ocular reflex
and optokinetic response in mice. Neurosci Res 39: 299-311,
2001
- Yamasaki T, Kawaji K, Ono K, Bito H, Hirano T, Osumi N, Kengaku
M: Pax6 regulates granule cell polarization during parallel fiber
formation in the developing cerebellum. Development 128: 3133-3144,
2001
- Kawaguchi S, Hirano T: Signaling cascade regulating long-term potentiation
of GABAA receptor responsiveness in cerebellar Purkinje
neurons. J Neurosci 22: 3969-3976, 2002
- Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M: Delta/Notch-like
epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing
protein targeted to dendrites of developing and adult central nervous
system neurons. J Biol Chem 277: 25400-25407, 2002
- Fujii H, Hirano T: Calcineurin regulates induction of late phase
of cerebellar long-term depression in rat cultured Purkinje neurons.
Eur J Neurosci 16: 1777-1788, 2002
- Hirano, T, Watanabe D, Kawaguchi S, Pastan I, Nakanishi S: Roles
of inhibitory interneurons in the cerebellar cortex. Ann N Y Acad
Sci 978: 405-412, 2002
- Minami I, Kengaku M, Sillevis Smitt P, Shigemoto R, Hirano T: Long-term
potentiation of mGluR1 activity by depolarization-induced Homer 1a
in cerebellar Purkinje neurons. Eur J Neurosci 17: 1023-1032,
2003
- Coesmans M, Smitt PA, Linden DJ, Shigemoto R, Hirano T, Yamakawa
Y, van Alphen AM, Luo C, van der Geest JN, Kros JM, Gaillard CA, Frens
MA, de Zeeuw CI: Mechanism underlying cerebellar motor deficits due
to mGluR1-autoantibodies. Ann Neurol 53: 325-336, 2003
- Kitano J, Nishida M, Itsukaichi Y, Minami I, Ogawa M, Hirano T,
Mori Y, Nakanishi S: Direct interaction and functional coupling between
metabotropic glutamate receptor subtype 1 and voltage-sensitive CaV2.1
Ca2+ channel. J Biol Chem 278: 25101-25108, 2003
- Murai N, Tsuji J, Ito J, Mishina M, Hirano T: Vestibular compensation
in glutamate receptor δ-2 subunit knockout mice: dynamic property
of vestibule-ocular reflex. Eur Arch Oto-Rhino-Laryngol 65:
82-86, 2004
- Kawaji, K, Umeshima H, Eiraku M, Hirano T, Kengaku M: Dual phases
of migration of cerebellar granule cells guided by axonal and dendritic
leading processes. Mol Cell Neurosci 25: 228-240, 2004
- Yoshida T, Katoh A, Ohtsuki G, Mishina M, Hirano T: Oscillating
Purkinje neuron activity causing involuntary eye movement in a mutant
mouse deficient in the glutamate receptor δ2 subunit. J Neurosci
24: 2440-2448 2004
- Shima Y, Kengaku M, Hirano T, Takeichi M, Uemura T: Regulation of
dendritic maintenance and growth by a mammalian 7-pass transmembrane
cadherin. Dev Cell 7: 205-216, 2004
- Ohtsuki G, Kawaguchi S, Mishina M, Hirano T: Enhanced inhibitory
synaptic transmission in the cerebellar molecular layer of the GluRδ2
knockout mouse. J Neurosci 24: 10900-10907, 2004
- Katoh A, Yoshida T, Himeshima Y, Mishina M, Hirano T: Defective
control and adaptation of reflex eye movements in mutant mice deficient
in either the glutamate receptor δ2 subunit or Purkinje cells.
Eur J Neurosci 21: 1315-1326, 2005
- Eiraku M, Tohgo A, Ono K, Kaneko M, Fujishima K, Hirano T, Kengaku
M: DNER acts as a neuron-specific Notch ligand during Bergmann glial
development. Nat Neurosci 8: 873-880, 2005
‹Àê@“Ä@i_ŒË‘åŠwE‘åŠw‰@ˆãŠwŒnŒ¤‹†‰Èj
- Maejima T, Hashimoto K, Yoshida T, Aiba A, Kano M: Presynaptic inhibition
caused by retrograde signal from metabotropic glutamate to cannabinoid
receptors. Neuron 31: 463-475, 2001
- Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K,
Mishina M, Hashikawa T, Konnerth A, Watanabe M, Kano M: Roles of glutamate
receptor δ2 subunit (GluR δ2) and metabotropic glutamate
receptor subtype 1 (mGluR1) in climbing fiber synapse elimination
during postnatal cerebellar development. J Neurosci 21: 9701-9712,
2001
- Shutoh F, Katoh A, Kitazawa H, Aiba A, Itohara S, Nagao S: Loss
of adaptability of horizontal optokinetic response eye movements in
mGluR1 knockout mice. Neurosci Res 42: 141-145, 2002
- Tabata T, Aiba A, Kano M: Extracellular calcium controls the dynamic
range of neuronal metabotropic glutamate receptor responses. Mol
Cell Neurosci 20: 56-68, 2002
- Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura
T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie
S: Pioglitazone improves the phenotype and molecular defects of a
targeted Pkd1 mutant. Hum Mol Genet 11: 1731-1742, 2002
- Kishimoto Y, Fujimichi R, Araishi K, Kawahara S, Kano M, Aiba A,
Kirino Y: mGluR1 in cerebellar Purkinje cells is required for normal
association of temporally contiguous stimuli in classical conditioning.
Eur J Neurosci 16: 2416-2424, 2002
- Chida K, Hara T, Hirai T, Konishi C, Nakamura K, Nakao K, Aiba A,
Katsuki M, Kuroki T: Disruption of protein kinase Ceta results in
impairment of wound healing and enhancement of tumor formation in
mouse skin carcinogenesis. Cancer Res 63: 2404-2408, 2003
- Kuwajima M, Hall RA, Aiba A, Smith Y: Subcellular and subsynaptic
localization of group I metabotropic glutamate receptors in the monkey
subthalamic nucleus. J Comp Neurol 474: 589-602, 2004
- Nakamura M, Sato K, Fukaya M, Araishi K, Aiba A, Kano M, Watanabe
M: Signaling complex formation of phospholipase Cβ4 with metabotropic
glutamate receptor type 1α and 1,4,5-tris-phosphate receptor
at the perisynapse and endoplasmic reticulum in the mouse brain. Eur
J Neurosci 20: 2929-2944, 2004
- Tomemori Y, Ichiba M, Kusumoto A, Mizuno E, Sato D, Muroya S, Nakamura
M, Kawaguchi H, Yoshida H, Ueno S, Nakao K, Nakamura K, Aiba A, Katsuki
M, Sano A: A gene-targeted mouse model for chorea-acanthocytosis.
J Neurochem 92: 759-766, 2005
- Maejima T, Oka S, Hashimotodani Y, Ohno-Shosaku T, Aiba A, Wu D,
Waku K, Sugiura T, Kano M: Synaptically-driven endocannabinoid release
requires Ca2+-assisted mGluR1-PLCβ4 signaling cascade in the
cerebellum. J Neurosci 25: 6826-6835, 2005
ÎŒ´@Œ’i‹ãB‘åŠwE‘åŠw‰@—ŠwŒ¤‹†‰@j
- Ohkura K, Suzuki
N, Ishihara T, Katsura I: SDF-9, a protein tyrosine pshophatse-like molecule,
regulates the L3/dauer developmental decision through hormonal signaling in C. elegans. Development 130: 3237-3248, 2003
- Miyahara K, Suzuki
N, Ishihara T, Tsuchiya E, Katsura I: TBX2/TBX3 transcriptional factor homolog
controls olfactory adaptation in
Caenorhabditis elegans.J Neurobiol 58: 392-402, 2004
- Take-Uchi M, Kobayashi
Y, Kimura KD, Ishihara T, Katsura I: FLR-4, a novel serine/threonine protein
kinase, regulates defecation rhythm in Caenorhabditis
elegans. Mol Biol Cell 16:
1355-1365, 2005
ˆäã‹M•¶@i“Œ‹ž‘åŠwEˆã‰ÈŠwŒ¤‹†Šj
- Kuruma A, Inoue T, Mikoshiba K: Dynamics of Ca2+ and
Na+ in the dendrite of mouse cerebellar Purkinje cells
evoked by parallel fiber stimulation. Eur J Neurosci 18: 2677-2689,
2003
- Fukami K, Yoshida M, Inoue T, Kurokawa M, Fissore RA, Yoshida N,
Mikoshiba K, Takenawa T: Phospholipase Cδ4 is required for Ca2+-mobilization
essential for acrosome reaction in sperm. J Cell Biol 161:
79-88, 2003
- Minoshima Y, Kawashima T, Hirose K, Tonozuka Y, Kawajiri A, Bao
YC, Deng X, Tatsuka M, Narumiya S, Stratford May JrW, Nosaka T, Semba
K, Inoue T, Satoh T, Inagaki M, Kitamura T: Phosphorylation by aurora
B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell
4: 549-560, 2003
- Nagase T, Ito KI, Kato K, Kaneko K, Kohda K, Matsumoto M, Hoshino
A, Inoue T, Fujii S, Kato H, Mikoshiba K: Long-term potentiation and
long-term depression in hippocampal CA1 neurons of mice lacking the
IP3 type 1 receptor. Neuroscience 117: 821-830,
2003
- Yasuda H, Higashi H, Kudo Y, Inoue T, Hata Y, Mikoshiba K, Tsumoto
T: Imaging of calcineurin activated by long-term depression-inducing
synaptic inputs in living neurons of rat visual cortex. Eur J Neurosci
17: 287-297, 2003
ˆäƒmŒû@Š]@iŽO•H‰»Šw¶–½‰ÈŠwŒ¤‹†ŠEŒ¤‹†•”–åj
- Matsuo R, Murayama A, Saitoh
Y, Sakaki Y, Inokuchi K: Identification and cataloging of genes induced by
long-lasting long-term potentiation in awake rats. J Neurochem 74: 2239-2249, 2000
- Ikegami S, Inokuchi K:
Antisense DNA against calcineurin facilitates memory in contextual fear
conditioning by lowering the threshold for hippocampal long-term potentiation
induction. Neuroscience 98: 637-646,
2000
- Saitoh Y, Inokuchi K: A
triphasic curve characterizes the retention of lever-pressing behavior rewarded
by lateral hypothalamic stimulation during the immediate-posttrial period in
rats: implications for a transient intermediate stage between short and
long-term memory. Neurosci Res 37:
211-219, 2000
- Tanaka T, Sugai M, Ito Y,
Inokuchi K, Kohno T: Assignments of the 1H, 13C, and 15N
resonances of the 21 kDa Vesl/Homer family protein, Vesl-1S. J Biomol NMR 18: 181-182, 2000
- Kato A, Fukuda T, Fukazawa Y,
Isojima Y, Fujitani K, Inokuchi K, Sugiyama H: Phorbol esters promote
postsynaptic accumulation of Vesl-1S/Homer-1a protein. Eur J Neurosci 13: 1292-1302, 2001
- Shinohara T, Tomizuka K, Miyabara S, Takehara S, Kazuki Y, Inoue
J, Katoh M, Nakane H, Iino A, Ohguma A, Ikegami S, Inokuchi K, Ishida I, Reeves
RH, Oshimura M: Mice containing a human chromosome 21 model behavioral impairment and
cardiac anomalies of Downfs syndrome. Hum
Mol Genet 10: 1163-1175, 2001
- Yamazaki M, Matsuo R,
Fukazawa Y, Ozawa F, Inokuchi K: Regulated expression of an actin-associated
protein, synaptopodin, during long-term potentiation. J Neurochem 79: 192-199, 2001
- Matsuo R, Asada A, Fujitani
K, Inokuchi K: LIRF, a gene induced during hippocampal long-term potentiation
as an immediate-early gene, encodes a novel RING finger protein. Biochem Biophys Res Commun 289: 479-484,
2001
- Ageta H, Kato A, Fukazawa Y,
Inokuchi K, Sugiyama H: Effects of proteasome inhibitors on the synaptic
localization of Vesl-1S/Homer-1a proteins. Mol
Brain Res 97: 186-189, 2001
- Inoue Y, Honkura
N, Kato A, Ogawa S, Udo H, Inokuchi K, Sugiyama H: Activity-inducible protein
Homer1a/Vesl-1S promotes redistribution of postsynaptic protein Homer1c/Vesl-1L
in cultured rat hippocampal neurons. Neurosci
Lett 354: 143-147, 2004
- Inaba Y, Tian QB, Okano A, Zhang JP, Sakagami H,
Miyazawa S, Li W, Komiyama A, Inokuchi K, Kondo H, Suzuki T: Brain-specific
novel guanine nucleotide exchange factor for Arf, synArfGEF, is localized to
postsynaptic density. J Neurochem
89: 1347-1357, 2004
- Sugiyama K, Niki
T, Inokuchi K, Teranishi Y, Ueda M, Tanaka A: Hterologous expression of
metabotropic glutamate receptor subtype 1 in Saccharomyces cerevisiae. Appl
Microbiol Biotechnol 64: 531-536,
2004
- Inoue K, Fukazawa
Y, Ogura A, Inokuchi K: Two-dimensional neural activity mapping of the entire
population of hippocampal CA1 pyramidal cells responding to fear conditioning. Neurosci Res 51: 417-425, 2005
- Sakagami Y, Yamamoto
K, Sugiura S, Inokuchi K, Hayashi T, Kato N: Roles of Homer-1a in homeostatic
regulation of pyramidal cell excitability: a possible link to clinical benefits
of electroconvalsive shock. Eur J
Neurosci 21: 3229-3239, 2005
- Yamamoto K, Sakagami Y, Sugiura S, Inokuchi K,
Shimohama S, Kato N: Homer-1a enhances spike-induced calciiuminflux via l-type calcium
channels in neocortex pyramidal cells. Eur
J Neurosci 22: 1338-1348, 2005
- Ehrengruber M,
Kato A, Inokuchi K, Hennou S: Homer/Vesl proteins and their roles in CNS
neurons. Mol Neurobiol 29: 213-228,
2004
‰œ“c@—²Žu@i“Œ‹ž‘åŠwE‘åŠw‰@ˆãŠwŒnŒ¤‹†‰Èj
- Okuda T, Haga T:
Functional characterization of the human high-affinity choline transporter. FEBS Lett 484: 92-97, 2000
- Misawa H, Nakata
K, Matsuura J, Nagao M, Okuda T, Haga T: Distribution of the high-affinity
choline transporter in the central nervous system of the rat. Neuroscience 105: 87-98, 2001
- Kobayashi Y, Okuda
T, Fujioka Y, Matsumura G, Nishimura Y, Haga T: Distribution of the
high-affinity choline transporter in the human and macaque monkey spinal cord. Neurosci Lett 317: 25-28, 2002
- Okuda T, Okamura
M, Kaitsuka C, Haga T, Gurwitz D: Single nucleotide polymorphism of the human
high affinity choline transporter alters transport rate. J Biol Chem 277: 45315-45322, 2002
‰Í¼@t˜Y@i‰ªè‘—§‹¤“¯Œ¤‹†‹@\¶—ŠwŒ¤‹†ŠE¶‘Ì–Œ•”–åj
- Tsubamoto Y, Eto K, Noda
M, Daniel S, Suga S, Yamashita S, Kasai H, Wakui M, Sharp GW, Kimura S,
Kadowaki T: Hexamminecobalt (III) chloride inhibits glucose-induced insulin
secretion at the exocytotic process. J Biol Chem276: 2979-2985, 2001
- Nemoto T, Kimura R, Ito K,
Tachikawa A, Miyashita Y, Iino M, Kasai H: Sequential replenishment
mechanism of exocytosis in pancreatic acini. Nat Cell Biol 3: 253-258, 2001
- Kishimoto T, Liu
TT, Ninomiya Y, Takagi H, Yoshioka T, Ellis-Davies GC, Miyashita Y, Kasai H: Ion selectivities
of the Ca2+ sensors for exocytosis in rat phaeochromocytoma cells. J Physiol 533: 627-637, 2001
- Matsuzaki
M, Ellis-Davies GC, Nemoto T, Miyashita Y, Iino M, Kasai H:
Dendritic spine geometry is critical for AMPA receptors expression in
hippocampal CA1 pyramidal neurons. Nat
Neurosci4: 1086-1092, 2001
Š‘@Gl@i‚’m‘åŠwEˆãŠw•”j
- Okere CO, Kaba H: Region-specific localization of glutamine synthetase
immunoreactivity in the mouse olfactory bulb: implication for neuron-glia
interaction in bulbar synaptic plasticity. Brain Res 857: 308-312,
2000
- Okere CO, Kaba H, Higuchi T: Differential activation of Fos-like
immunoreactivity in the arcuate nuleus and amygdala after intracerebroventricular
injection of sodium nitroprusside and Nw-nitro-L-arginine
in conscious and urethane-anesthetized lactating rats. Neurosci
Lett 283: 189-192, 2000
- Okere CO, Kaba H, Higuchi T: Importance of endogenous nitric oxide
synthase in the rat hypothalamus and amygdala in mediating the response
to capsaicin. J Comp Neurol 423: 670-686, 2000
- Osako Y, Otsuka T, Taniguchi M, Oka T, Kaba H: Oxytocin depresses
spontaneous γ-aminobutyric acid-ergic inhibitory postsynaptic
currents in cultured mitral cells of the rat olfactory bulb by a presynaptic
mechanism. Neurosci Lett 289: 25-28, 2000
- Okere CO, Kaba H: Heterogenous immunohistochemical expression of
microglia-specific ionized calcium binding adaptor protein (Iba 1)
in the mouse olfactory bulb. Brain Res 877: 85-90, 2000
- Zhang JJ, Okutani F, Yagi F, Inoue S, Kaba H: Facilitatory effect
of ritanserin is mediated by dopamine D1 receptors on olfactory
learning in young rats. Dev Psychobiol 37: 246-252, 2000
- Okere CO, Kaba H: Increased expression of neuronal nitric oxide
synthase mRNA in the accessory olfactory bulb during the formation
of olfactory recognition memory in mice. Eur J Neurosci 12:
4552-4556, 2000
- Osako Y, Otsuka T, Taniguchi M, Oka T, Kaba H: Oxytocin enhances
presynaptic and postsynaptic glutamatergic transmission between rat
olfactory bulb neurones in culture. Neurosci Lett 299: 65-68,
2001
- Otsuka T, Ishii K, Osako Y, Okutani F, Taniguchi M, Oka T, Kaba
H: Modulation of dendrodendritic interactions and mitral cell excitability
in the mouse accessory olfactory bulb by vaginocervical stimulation.
Eur J Neurosci 13: 1833-1838, 2001
- Otsuka T, Hashida M, Oka T, Kaba H: Activation of GABAA
receptors in the accessory olfactory bulb does not prevent the formation
of an olfactory memory in mice. J Vet Med Sci 63: 807-809,
2001
- Taniguchi M, Kaba H: Properties of reciprocal synapses in the mouse
accessory olfactory bulb. Neuroscience 108: 365-370, 2001
- Okutani F, Zhang JJ, Yagi F, Kaba H: Non-specific olfactory aversion
induced by intrabulbar infusion of the GABAA receptor antagonist
bicuculline in young rats. Neuroscience 112: 901-906, 2002
- Zhang JJ, Okutani F, Inoue S, Kaba H: Activation of the cyclic AMP
response element-binding protein signaling pathway in the olfactory
bulb is required for the acquisition of olfactory aversive learning
in young rats. Neuroscience117: 707-713, 2003
- Zhang JJ, Okutani F, Inoue S, Kaba H: Activation of the mitogen-activated
protein kinase/extracellular signal-regulated kinase signaling pathway
leading to cyclic AMP response element-binding protein phosphorylation
is required for the long-term facilitation process of aversive olfactory
learning in young rats. Neurosicence 121: 9-16, 2003
- Okutani F, Zhang JJ, Otsuka T, Yagi F, Kaba H: Modulation of olfactory
learning in young rats through intrabulbar GABAB receptors.
Eur J Neurosci 18: 2031-2036, 2003
- Matsuoka M, Kaba H, Moriya K, Yoshida-Matsuoka J, Costanzo RM, Norita
M, Ichikawa M: Remodeling of reciprocal synapses associated with persistence
of long-term memory. Eur J Neurosci 19: 1668-1672, 2004
- Muramoto K, Kato-Negishi M, Kuroda Y, Kaba H, Ichikawa M: Differences
in development and cellular composition between neuronal cultures
of rat accessory and main olfactory bulbs. Anat Embryol 209:
129-136, 2004
_’J‰·”V@i–kŠC“¹‘åŠwE‘åŠw‰@ˆãŠwŒ¤‹†‰Èj
- Tabata
Y, Ouchi Y, Kamiya H, Manabe T, Arai K, Watanabe S: Specification of the
retinal fate of mouse embryonic stem cells by ectopic expression of Rx/rax, a
homeobox gene. Mol Cell Biol 24:
4513-4521, 2004
- Nakatsu F, Okada M, Mori F, Kumazawa N, Iwasa H,
Zhu G, Kasagi Y, Kamiya H, Harada A, Nishimura K, Takeuchi A, Miyazaki T,
Watanabe M, Yuasa S, Manabe T, Wakabayashi K, Kaneko S, Saito T, Ohno H:
Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B
clathrin adaptor. J Cell Biol 167:
293-302, 2004
ìŒË@‰À@i“Œ‹ž‘åŠwE‘åŠw‰@‘‡•¶‰»Œ¤‹†‰Èj
- Takahashi T, Kimoto T, Tanabe N, Hattori T, Yasumatsu N, Kawato
S: Corticosterone acutely prolonged N-methyl-D-aspartate receptor-mediated
Ca2+ elevation in cultured rat hippocampal neurons.
J Neurochem 83: 1441-1451, 2002
- Takata N, Shibuya K, Okabe M, Nagano T, Kojima H, Kawato S: Pregnenolone
sulfate acutely enhances NO production in the rat hippocampus: digital
fluorescence study using NO reactive dye. Bioimages 10: 1-8,
2002
- Kimoto T, Tsurugizawa T, Ohta Y, Makino J, Tamura H, Hojo Y, Takata
N, Kawato S: Neurosteroid synthesis by cytochrome P450-containing
systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate
and calcium-dependent synthesis. Endocrinology 142: 3578-3589,
2001
- Yamada M, Ohta Y, Bachmanova GI, Archakov AI, Hatta I, Kawato S:
Effect of microsome-liposome fusion on the rotational mobility of
cytochrome P450IIB4 in rabbit liver microsomes. J Inorg Biochem
83: 261-268, 2001
‹Ë–ì@–L@i“Œ‹ž‘åŠwE‘åŠw‰@–òŠwŒnŒ¤‹†‰Èj
- Tomita S, Fujita T, Kirino Y, Suzuki T: PDZ domain-dependent suppression
of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like
protein. J Biol Chem 275: 13056-13060, 2000
- Inoue T, Watanabe S, Kawahara S, Kirino Y: Phase-dependent filtering
of sensory information in the oscillatory olfactory center of a terrestrial
mollusk. J Neurophysiol 84: 1112-1115, 2000
- Lee DS, Tomita S, Kirino Y, Suzuki T: Regulation of X11L-dependent
amyloid precursor protein metabolism by XB51, a novel X11L-binding
protein. J Biol Chem 275: 23134-23138, 2000
- Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, Greengard
P, Kirino Y, Nairn AC, Suzuki T: Neuron-specific phosphorylation of
Alzheimerfs beta-amyloid precursor protein by cyclin-dependent kinase
5. J Neurochem 75: 1085-1091, 2000
- Lee DS, Hirashima N, Kirino Y: Rapid transbilayer phospholipid redistribution
associated with exocytotic release of neurotransmitters from cholinergic
nerve terminals isolated from electric ray Narke japonica.
Neurosci Lett 291: 21-24, 2000
- Toda S, Kawahara S, Kirino Y: Image analysis of olfactory responses
in the procerebrum of the terrestrial slug Limax marginatus.
J Exp Biol 203: 2895-2905, 2000
- Nakaya T, Kawahara S, Watanabe S, Suzuki T, Kirino Y: Identification
and expression of a novel gene in odour-taste associative learning
in the terrestrial slug. Genes Cells 6: 43-56, 2001
- Kishimoto Y, Kawahara S, Mori H, Mishina M, Kirino Y: Long-trace
interval eyeblink conditioning is impaired in mutant mice lacking
the NMDA receptor subunit epsilon 1. Eur J Neurosci 13: 1221-1227,
2001
- Kishimoto Y, Kawahara S, Suzuki M, Mori H, Mishina M, Kirino Y:
Classical eyeblink conditioning in glutamate receptor subunit delta
2 mutant mice is impaired in the delay paradigm but not in the trace
paradigm. Eur J Neurosci 13: 1249-1253, 2001
- Watanabe S, Inoue T, Murakami M, Inokuma Y, Kawahara S, Kirino Y:
Modulation of oscillatory neural activities by cholinergic activation
of interneurons in the olfactory center of a terrestrial slug. Brain
Res 896: 30-35, 2001
- Shindo K, Shinozaki K, Kami K, Anzai K, Lee S, Aoyagi H, Kirino
Y, Shimada I: Solution structure of micelle-bound H5 peptide (427-452):
a primary structure corresponding to the pore forming region of the
voltage dependent potassium channel. Biochim Biophys Acta 1545:
153-159, 2001
- Satoh Y, Hirakura Y, Shibayama S, Hirashima N, Suzuki T, Kirino
Y: β-Amyloid peptides inhibit acetylcholine release from cholinergic
presynaptic nerve endings isolated from an electric ray. Neurosci
Lett 302: 97-100, 2001
- Inoue T, Watanabe S, Kirino Y: Serotonin and NO complementarily
regulate generation of oscillatory activity in the olfactory CNS of
a terrestrial mollusk. J Neurophysiol 85: 2634-2638, 2001
- Ando K, Iijima K, Elliott JI, Kirino Y, Suzuki T: Phosphorylation-dependent
regulation of the interaction of amyloid precursor protein with Fe65
affects the production of β-amyloid. J Biol Chem 276:
40353-40361, 2001
- Takatsuki K, Kawahara S, Takehara K, Kishimoto Y, Kirino Y: Effects
of the noncompetitive NMDA receptor antagonist MK-801 on classical
eyeblink conditioning in mice. Neurophamacology 41: 618-628,
2001
- Kishimoto Y, Suzuki M, Kawahara S, Kirino Y: Age-dependent impairment
of delay and trace eyeblink conditioning in mice. NeuroReport
12: 3349-3352, 2001
- Kishimoto Y, Kawahara S, Fujimichi R, Mori H, Mishina M, Kirino
Y: Impairment of eyeblink conditioning in GluRδ2 mutant mice
depends on the temporal overlap between conditioned and unconditioned
stimuli. Eur J Neurosci 14: 1515-1521, 2001
- Hirono M, Sugiyama T, Kishimoto Y, Sakai I, Miyazawa T, Kishio M,
Inoue H, Nakao K, Ikeda M, Kawahara S, Kirino Y, Katsuki M, Horie
H, Ishikawa Y, Yoshioka T: Phospholipase Cbeta4 and protein kinase
Calpha and/or protein kinase CbetaI are involved in the induction
of long term depression in cerebellar Purkinje cells. J Biol Chem
276: 45236-45242, 2001
- Shimozono S, Watanabe S, Inoue T, Kirino Y: Identification and characterization
of an output neuron from the oscillatory molluscan olfactory network.
Brain Res 921: 98-105, 2001
- Muto Y, Matsuoka T, Kida A, Okano Y, Kirino Y: Blepharismin, produced
by the protozoan, Blepharisma japonicum, form ion-permeable
channels in planar lipid bilayer membranes. FEBS Lett 508:
423-426, 2001
- Takatsuki K, Kawahara S, Mori H, Mishina M, Kirino Y: Scopolamine
impairs eyeblink conditioning in cerebellar LTD-deficient mice. NeuroReport
13: 159-162, 2002
- Kotani S, Kawahara S, Kirino Y: Classical eyeblink conditioning
in decerebrate guinea pigs. Eur J Neurosci 15: 1267-1270, 2002
- Inokuma Y, Inoue T, Watanabe S, Kirino Y: Two types of network oscillations
and their odor responses in the primary olfactory center of a terrestrial
mollusk. J Neurophysiol 87: 3160-3164, 2002
- Shimozono S, Fukano T, Nagai T, Kirino Y, Mizuno H, Miyawaki A:
Confocal imaging of subcellular Ca2+ concentrations using
a dual-excitation ratiometric indicator based on green fluorescent
protein. Sciencefs STKE 125: l4, 2002
- Taru H, Iijima K, Hase M, Kirino Y, Yagi Y, Suzuki T: Interaction
of Alzheimerfs β-amyloid precursor family proteins with scaffold
proteins of the JNK signaling cascade. J Biol Chem 277: 20070-20078,
2002
- Taru H, Kirino Y, Suzuki T: Differential roles of JIP scaffold proteins
in the modulation of amyloid precursor protein metabolism. J Biol
Chem 277: 27567-27574, 2002
- Shibayama S, Shibata-Seita R, Miura K, Kirino Y, Takishima K: Identification
of a C-terminal region that is required for the nuclear translocation
of ERK2 by passive diffusion. J Biol Chem 277: 37777-37782,
2002
- Takehara K, Kawahara S, Takatsuki K, Kirino Y: Time-limited role
of the hippocampus in the memory for trace eyeblink conditioning in
mice. Brain Res 951: 183-190, 2002
- Matsuo R, Hitomi T, Watanabe S, Kirino Y: Delayed-onset amnesia
caused by protein synthesis inhibition in odor-taste associative memory
of terrestrial slug Limax valentianus. Neurosci Lett 334:
201-205, 2002
- Kishimoto Y, Fujimichi R, Araishi K, Kawahara S, Kano M, Aiba A,
Kirino Y: mGluR1 in cerebellar Purkinje cells is required for normal
association of temporally contiguous stimuli in classical conditioning.
Eur J Neurosci 16: 2416-2424, 2002
- Takatsuki K, Kawahara S, Kotani S, Mori H, Mishina M, Kirino Y:
Hippocampal damage disrupts eyeblink conditioning in mice lacking
glutamate receptor subunit δ2. J Biol Phys 28: 539-547,
2002
‹v•Û@‹`O@iŽ©‘R‰ÈŠwŒ¤‹†‹@\E¶—ŠwŒ¤‹†Šj
- Kubo Y, Murata Y: Control of rectification and permeation by two
distinct sites after the second transmembrane region in Kir2.1 K+
channel. J Physiol 531: 645-660, 2001
- Saitoh O, Masuho I, Terakawa I, Nomoto S, Asano T, Kubo Y: Regulator
of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular
localization and acute desensitization of G protein-gated K+
channels. J Biol Chem 276: 5052-5058, 2001
- Soom M, Schonherr R, Kubo Y, Kirsch C, Klinger R, Heinemann SH:
Multiple PIP2 binding sites in Kir2.1 inwardly rectifying
potassium channels. FEBS lett 490: 49-53, 2001
- Murata Y, Okado H, Kubo Y: Characterization of heteromultimeric
G-protein coupled inwardly rectifying potassium channels of the tunicate
tadpole with a unique property. J Biol Chem 276: 18529-18539,
2001
- Murata Y, Okado H, Katsuyama Y, Okamura Y, Kubo Y: Primary structure,
developmental expression and functional properties of an inward rectifier
K+ channel of the tunicate. Receptors Channels 7:
387-399, 2001
- Misaka T, Miyashita T, Kubo Y: Primary structure of a dynamin-related
mouse mitochondrial GTPase and its distribution in brain, subcellular
localization and effect on mitochondrial morphology. J Biol Chem
277: 15834-15842, 2002
- Ai T, Fujiwara Y, Tsuji K, Otani H, Nakano S, Kubo Y, Horie M: Novel
KCNJ2 mutation in familial periodic paralysis with ventricular dysrhythmia.
Circulation 105: 2592-2594, 2002
- Saitoh O, Murata Y, Odagiri M, Itoh M, Itoh H, Misaka T, Kubo Y:
Alternative splicing of RGS8 gene determines inhibitory function of
receptor-type-specific Gq signaling. Proc Natl Acad Sci USA
99: 10138-10143, 2002
- Murata Y, Fujiwara Y, Kubo Y: Identification of a site involved
in the block by extracellular Mg2+ and Ba2+
as well as permeation of K+ in Kir2.1 K+ channel.
J Physiol 544: 665-677, 2002
- Fujiwara Y, Kubo Y: Ser 165 in the second transmembrane region of
the Kir2.1 channel determines its susceptibility to blockade by intracellular
Mg2+. J Gen Physiol 120: 677-692, 2002
- Abe H, Misaka T, Tateyama M, Kubo Y: Effects of co-expression with
Homer isoforms on the function of metabotropic glutamate receptor1a.
Mol Cell Neurosci 23: 157-168, 2003
- Abe, H., Tateyama, M. and Kubo, Y.FFunctional identification of
Gd3+ binding site of metabotropic glutamate receptor1a. FEBS letter
545F233-238, 2003
- Fujiwara Y, Kubo Y: Density dependent changes of the pore properties
of P2X2 receptor channel. J Physiol 558: 31-43,
2004
- Tateyama M, Abe H, Nakata H, Saito O, Kubo Y: Ligand-induced rearrangement
of the intracellular dimeric conformation of metabotropic glutamate
receptor1a. Nat Struct Mol Biol 11: 637-642, 2004
- Ju WK, Misaka T, Kushnareva Y, Nakagomi S, Agarwal N, Kubo Y, Lipton
SA, Bossy-Wetzel E: OPA1 expression in the normal rat retina and optic
nerve. J Comp Neurol 488: 1-10, 2005
- Itoh M, Nagatomo K, Kubo Y, Sugimoto M, Saitoh O: Molecular cloning
and characterization of a new RGS protein of Medaka. Gene
345: 165-171, 2005
Œã“¡@ŒO@iŽRŒ`‘åŠwEˆãŠw•”j
- Shirai Y, Segawa S, Kuriyama M, Goto K, Sakai N,
Saito N: Subtype-specific translocation of diacylglycerol kinase alpha and
gamma and its correlation with protein kinase C. J Biol Chem 275: 24760-24766, 2000
- Takeda M, Kagaya Y, Takahashi J, Sugie T, Ohta J,
Watanabe J, Shirato K, Kondo H, Goto K: Gene expression and in situ
localization of diacylglycerol kinase isozymes in normal and infarcted rat
hearts: effects of captopril treatment. Circ Res 89: 265-272, 2001
- Caricasole A, Bettini E, Sala C, Roncarati R,
Kobayashi N, Caldara F, Goto K, Terstappen GC: Molecular cloning and
characterization of the human diacylglycerol kinase beta (DGKbeta) gene:
alternative splicing generates DGKbeta isotypes with different properties. J Biol Chem 277: 4790-4796, 2002
¬—Ñ@˜al@i•Ÿ“‡Œ§—§ˆã‰È‘åŠwEˆãŠw•”j
- Matsushita N,
Okada H, Yasoshima Y, Takahashi K, Kiuchi K, Kobayashi K: Dynamics of tyrosine hydroxylase promoter activity during midbrain
dopaminergic neuron development. J
Neurochem 82: 295-304, 2002
- Baker H, Kobayashi
K, Okano H, Saino-Saito S: Cortical and striatal
expression of tyrosine hydroxylase mRNA in neonatal and adult mice. Cell Mol Neurobiol 23: 507-518, 2003
- Sano H, Yasoshima Y,
Matsushita N, Kaneko T, Kohno K, Pastan I, Kobayashi K: Conditional ablation of
striatal neuronal types containing dopamine D2 receptor disturbs coordination
of basal ganglia function. J Neurosci23:
9078-9088, 2003
- Shin RM, Masuda M, Miura
M, Sano H, Shirasawa T, Song WJ, Kobayashi K, Aosaki T: Dopamine D4
receptor-induced postsynaptic inhibition of GABAergic currents in mouse globus
pallidus neurons. J Neurosci 23:
11662-11672, 2003
- Kobayashi K, Takahashi M,
Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K: Survival of
developing motor neurons by Rho GTPase signaling pathway
through Rho-kinase. J Neurosci 24: 3480-3488,
2004
- Okada
H, Matsushita N, Kobayashi K, Kobayashi K: Identification of GABAA
receptor subunit variants in midbrain dopaminergic neurons. J Neurochem 89: 7-14, 2004
- Yoshizaki T, Inaji M,
Kouike H, Shimazaki T, Sawamoto K, Ando K, Date I, Kobayashi K, Suhara T,
Uchiyama Y, Okano H: Isolation and transplantation of dopaminergic neurons generated from
mouse embryonic stem cells. Neurosci
Lett 363: 33-37, 2004
- Matsushita N, Kobayashi K,
Miyazaki J, Kobayashi K: Fate of transient catecholaminergic cell types
revealed by site-specific recombination in transgenic mice. J Neurosci Res 78: 7-15, 2004
- Saino-Saito S, Sasaki H, Volpe BT, Kobayashi K, Berlin R, Baker H: Differentiation
of the dopaminergic phenotype in the olfactory system of neonatal and adult
mice. J Comp Neurol 479: 389-398,
2004
- Pignatelli A, Kobayashi K,
Okano H, Belluzzi O: Functional properties of dopaminergic neurons in the mouse
olfactory bulb. J Physiol 564:
501-514, 2005
- Matsusaka T, Xin J, Niwa S, Kobayashi K, Akatsuka A, Hashizume H,
Wang QC, Pastan I, Fogo AB, Ichikawa I: Genetic engineering
of glomerular sclerosis in the mouse via control of onset and severity of
podocyte-specific injury. J Am Soc
Nephrol 16: 1013-1023, 2005
- Jomphe C, Bourque MJ, Fortin GD, St-Gelais F,
Okano H, Kobayashi K, Trudeau LE: Use of TH-GFP transgenic mice as a source of
identified dopaminergic neurons for physiological studies in postnatal cell
culture. J Neurosci Methods 146:
1-12, 2005
¬—Ñ‘ñ–ç@i‹ž“s‘åŠw‘åŠw‰@EˆãŠwŒ¤‹†‰Èj
- Matsuoka Y,
Furuyashiki T, Bito H, Ushikubi F, Tanaka Y, Kobayashi T, Muro S, Satoh N,
Kayahara T, Higashi M, Mizoguchi A, Shichi H, Fukuda Y, Nakao K, Narumiya S:
Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice
deficient in prostaglandin E receptor EP1 and EP3 subtypes. Proc Natl Acad Sci USA 100: 4132-4137,
2003
âV“¡@®—º@i_ŒË‘åŠwEƒoƒCƒIƒVƒOƒiƒ‹Œ¤‹†ƒZƒ“ƒ^[j
- Sumioka K, Shirai Y, Sakai N, Hashimoto T, Tanaka C, Yamamoto M,
Takahashi M, Ono Y, Saito N: Induction of 55 kDa PKN cleavage product
by ischemia/reperfusion model in the rat retina. Invest Opthal
Vis Sci 41: 29-35, 2000
- Sakai N, Kodama N, Ohmori S, Sasaki K, Saito N: Involvement of the
actin cytoskeleton in the regulation of serotonin transporter (SET)
activity: possible mechanism underlying SET regulation by protein
kinase C. Neurochem Int 36: 567-579, 2000
- Oyasu M, Kuroda S, Nakashita M, Fujimiya M, Kikkawa U, Saito N:
Immunocytochemical localization of a neuron-specific thrombospondin-1-like
protein, NELL2: Light and electron microscopic studies in the rat
brain. Mol Brain Res 76: 151-160, 2000
- Shirai Y, Kashiwagi K, Sakai N, Saito N: Phospholipase A2 and its
products are involved in the purinergic receptor-mediated translocation
of protein kinase C in CHO-K1 cells. J Cell Sci 113: 1335-1343,
2000
- Akiyama H, Kondoh T, Kokunai T, Nagashima T, Saito N, Tamaki N:
Blood-brain barrier formation of grafted human umbilical vein endothelial
cells in athymic mouse brain. Brain Res 858: 172-176, 2000
- Ueyama T, Ren Y, Ohmori S, Sakai K, Tamaki N, Saito N: cDNA cloning
of an alternative splicing variant of protein kinase Cδ (PKC
δIII), a new truncated form of PKCδ, in rats. Biochem
Biophys Res Commun 269: 557-563, 2000
- Shirai Y, Segawa S, Kuriyama M, Goto K, Sakai N, Saito N: Subtype-specific
translocation of diacylglycerol kinase alpha and gamma and its correlation
with protein kinase C. J Biol Chem 275: 24760-24766, 2000
- Nakagawa N, Hoshijima M, Oyasu M, Saito N, Tanizawa K, Kuroda S:
ENH, containing PDZ and LIM domain, heart/skeletal muscle-specific
protein, associates with cytoskeletal protein through its PDZ domain.
Biochem Biophys Res Commun 272: 505-512, 2000
- Shibaguchi H, Takemura K, Kan S, Kataoka Y, Kaibara M, Saito N,
Taniyama K: Role of synaptophysin in exocytic release of dopamine
from Xenopus oocytes injected with rat brain mRNA. Cell Mol Neurobiol
20: 401-408, 2000
- Ohmori S, Sakai N, Shirai Y, Yamamoto H, Miyamoto E, Shimizu N,
Saito N: Importance of PKC targeting for the phosphorylation of its
substrate, myristoylated alanine-rich C-kinase substrate (MARCKS).
J Biol Chem 275: 26449-26457, 2000
- Larsen EC, DiGennaro JA, Saito N, Mehta S, Loegering DJ, Mazurkiewicz
JE, Lennartz MR: Differential requirement for classic and novel PKC
isoforms in respiratory burst and phagocytosis in RAW 264.7 cells.
J Immunol 165: 2809-2817, 2000
- Yokogawa T, Nagata S, Nishio Y, Tsutsumi T, Ihara S, Shirai R, Morita
K, Umeda M, Shirai Y, Saitoh N, Fukui Y: Evidence that 3'-phosphorylated
polyphosphoinositides are generated at the nuclear surface: use of
immunostaining technique with monoclonal antibodies specific for PI
3,4-P2. FEBS Lett 473: 222-226, 2000
- Tozaki H, Kanno T, Nomura T, Kondoh T, Kodama N, Saito N, Aihara
H, Nagata T, Matsumoto S, Ohta K, Nagai K, Yajima Y, Nishizaki T:
Role of glial glutamate transporters in the facilitatory action of
FK960 on hippocampal neurotransmission. Mol Brain Res 97: 7-12,
2001
- Shindo M, Irie K, Ohigashi H, Kuriyama M, Saito N: Diacylglycerol
kinase γ is one of the specific receptors of tumor-promoting
phorbol esters. Biochem Biophys Res Commun 289: 451-456, 2001
- Kajimoto T, Ohmori S, Shirai Y, Sakai N, Saito N: Subtype-specific
translocation of the δ subtype of protein kinase C and its activation
by tyrosine phosphorylation induced by ceramide in HeLa cells. Mol
Cell Biol 21: 1769-1783, 2001
- Nakai M, Tanimukai S, Yagi K, Saito N, Taniguchi T, Terashima A,
Kawamata T, Yamamoto H, Fukunaga K, Miyamoto E, Tanaka C: Amyloid
β protein activates PKC-δ and induces translocation of myristoylated
alanine-rich C kinase substrate (MARCKS) in microglia. Neurochem
Int 38: 593-600, 2001
- Mishima K, Otani H, Tanabe T, Kawasaki H, Oshiro A, Saito N, Ogawa
R, Inagaki C: Molecular mechanisms for α2-adrenoceptor-mediated
regulation of synoviocytes populations. Jpn J Pharmacol 85:
214-226, 2001
- Saito-Ito A, Yagi K, Saito N: Distinct distribution of four Ca2+-dependent
subtypes of protein kinase C in rat olfactory bulb; definite expression
of βII-subtype in the accessory olfactory bulb. Neurochem
Int 39: 267-274, 2001
- Minami T, Hara K, Oshiro N, Ueoku S, Yoshino K, Tokunaga C, Shirai
Y, Saito N, Gout I, Yonezawa K: Distinct regulatory mechanism for
p70 S6 kinase beta from that for p70 S6 kinase alpha. Genes Cells
6: 1003-1015, 2001
- Ueyama T, Ren Y, Sakai N, Takahashi M, Ono Y, Kondoh T, Tamaki N,
Saito N: Constitutively active fragment of PKN in microglia/macrophage
after middle cerebral artery occlusion in rats. J Neurochem 79:
903-913, 2001
- Tada H, Uchino M, Nagai K, Nomura T, Kondoh T, Saito N, Yamamura
T, Yajima Y, Nishizaki T: The anti-dementia drug FK960 stimulates
glial glutamate release via a PKA pathway. Mol Brain Res 109:
63-8, 2002
- Kohjima M, Noda Y, Takeya R, Saito N, Takeuchi K, Sumimoto H: PAR3beta,
a novel homologue of the cell polarity protein PAR3, localizes to
tight junctions. Biochem Biophys Res Commun 299: 641-646, 2002
- Larsen EC, Ueyama T, Brannock PM, Shirai Y, Saito N, Larsson C,
Loegering D, Weber PB, Lennartz MR: Role for PKC-ε in FcγR-mediated
phagocytosis by RAW 264.7 cells. J Cell Biol 159: 939-944,
2002
- Zhang X, Kuroda S, Carpenter D, Nishimura I, Soo C, Moats R, Iida
K, Wisner E, Hu FY, Miao S, Beanes S, Dang C, Vastardis H, Longaker
M, Tanizawa K, Kanayama N, Saito N, Ting K: Craniosynostosis in transgenic
mice overexpressing Nell-1. J Clin Invest 110: 861-870, 2002
- Irie N, Sakai N, Ueyama T, Kajimoto T, Shirai Y, Saito N: Subtype-
and species-specific knockdown of PKC using short interfering RNA
(siRNA). Biochem Biophys Res Commun 298: 738-743, 2002
- Goerke A, Sakai N, Gutjahr E, Schlapkohl WA, Mushinski JF, Haller
H, Kolch W, Saito N, Mischak H: Induction of apoptosis by protein
kinase Cdelta is independent of its kinase activity. J Biol Chem
277: 32054-32062, 2002
- Ohta K, Nomura T, Kanno T, Nagai K, Yamamoto S, Yajima Y, Kondoh
T, Kohmura E, Saito N, Nishizaki T: L-trans-PDC enhances hippocampal
neuronal activity by stimulating glial glutamate release independently
of blocking transporters. Biophys Biochem Res Commun 295: 376-381,
2002
- Tanimukai S, Hasegawa H, Nakai M, Yagi K, Hirai M, Saito N, Taniguchi
T, Terashima A, Yasuda M, Kawamata T, Tanaka C: Nanomolar amyloid
beta protein activates a specific PKC isoform mediating phosphorylation
of MARCKS in Neuro2A cells. NeuroReport 13: 549-553, 2002
- Kashiwagi K, Shirai Y, Kuriyama M, Sakai N, Saito N: Importance
of C1B domain for lipid messenger-induced targeting of PKC. J Biol
Chem 277: 18037-18045, 2002
- Sakai K, Nakamura M, Ueno S, Sano A, Sakai N, Shirai Y, Saito N:
The silencer activity of the novel human serotonin transporter linked
polymorphic region. Neurosci Lett 327: 13-16, 2002
- Nishizaki T, Nagai K, Nomura T, Tada H, Kanno T, Tozaki H, Li XX,
Kondoh T, Kodama N, Takahashi E, Sakai N, Tanaka K, Saito N: A new
neuromodulatory pathway with a glial contribution mediated via A2a
adenosine receptors. Glia 39: 133-147, 2002
- Sawano A, Saito N, Miyawaki A: Multiple-colour fluorescence imaging
Ca2+-calmodulin, protein kinase C, and their conflicting convergence
on a shared target using novel epi-fluorescent microscopy. Biophys
J 82: 1076-1085, 2002
- Salli U, Saito N, Stormshak F: Spatio-temporal interactions of myristoylated
alanine-rich C kinase substrate (MARCKS) protein with the actin cytoskeleton
and exocytosis of oxytocin upon prostaglandin F2alpha stimulation
of bovine luteal cells. Biol Reprod 69: 2053-2058, 2003
- Fredholm BB, Assender JW, Irenius E, Kodama N, Saito N: Synergistic
effects of adenosine A1 and P2Y receptor stimulation on calcium mobilization
and PKC translocation in DDT1 MF-2 cells. Cell Mol Neurobiol 23:
379-400, 2003
- Sasaki A, Taketomi T, Kato R, Saeki K, Nonami A, Sasaki M, Kuriyama
M, Saito N, Shibuya M, Yoshimura A: Mammalian Sprouty4 suppresses
Ras-independent ERK activation by binding to Raf1. Nat Cell Biol
5: 427-432, 2003
- Shindo M, Irie K, Masuda A, Ohigashi H, Shirai Y, Miyasaka K, Saito
N: Synthesis and phorbol ester binding of the cysteine-rich domains
of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are
new targets of tumor-promoting phorbol esters. J Biol Chem
278: 18448-18454, 2003
- Mogami H, Zhang H, Suzuki Y, Urano T, Saito N, Kojima I, Petersen
OH: Decoding of short-lived Ca2+ influx signals into long term substrate
phosphorylation through activation of two distinct classes of protein
kinase C. J Biol Chem 278: 9896-9904, 2003
- Sakai K, Hasegawa C, Okura M, Morikawa O, Ueyama T, Shirai Y, Sakai
N, Saito N: Novel variants of murine serotonin transporter mRNA and
the promoter activity of its upstream sites. Neurosci Lett
342: 175-178, 2003
- Kuriyama M, Taniguchi T, Shirai Y, Sasaki A, Yoshimura A, Saito
N: Activation and translocation of PKCdelta is necessary for VEGF-induced
ERK activation through KDR in HEK293T cells. Biochem Biophys Res
Commun 325: 843-851, 2004
- Bhattacharjee AK, Ueyama T, Kondoh T, Hayashi S, Abouelfetouh A,
Sakai N, Saito N, Kohmura E: In vivo transgene expression using
an adenoviral tetracycline-regulated system with neuron-specific enolase
promoter. Biochem Biophys Res Commun 317: 1144-1148, 2004
- Ueyama T, Lennartz MR, Noda Y, Kobayashi T, Shirai Y, Rikitake K,
Yamasaki T, Hayashi S, Sakai N, Seguchi H, Sawada M, Sumimoto H, Saito
N: Superoxide production at phagosomal cup/phagosome through beta
I protein kinase C during Fc gamma R-mediated phagocytosis in microglia.
J Immunol 173: 4582-4589, 2004
- Sakai N, Tsubokawa H, Matsuzaki M, Kajimoto T, Takahashi E, Ren
Y, Ohmori S, Shirai Y, Matsubayashi H, Chen J, Duman RS, Kasai H,
Saito N: Propagation of γPKC translocation along the dendrites
of Purkinje cell in γPKC-GFP transgenic mice. Genes Cells
9: 945-957, 2004
- Kageyama A, Oka M, Okada T, Nakamura S, Ueyama T, Saito N, Hearing
VJ, Ichihashi M, Nishigori C: Down-regulation of melanogenesis by
phospholipase D2 through ubiquitin proteasome-mediated degradation
of tyrosinase. J Biol Chem 279: 27774-27780, 2004
- Yagi K, Shirai Y, Hirai M, Sakai N, Saito N: Phospholipase A2 products
retain a neuron specific gamma isoform of PKC on the plasma membrane
through the C1 domain--a molecular mechanism for sustained enzyme
activity. Neurochem Int 45: 39-47, 2004
- Kajimoto T, Shirai Y, Sakai N, Yamamoto T, Matsuzaki H, Kikkawa
U, Saito N: Ceramide-induced apoptosis by translocation, phosphorylation,
and activation of protein kinase Cdelta in the Golgi complex. J
Biol Chem 279: 12668-12676, 2004
- Uchino M, Sakai N, Kashiwagi K, Shirai Y, Shinohara Y, Hirose K,
Iino M, Yamamura T, Saito N: Isoform-specific phosphorylation of mGluR5
by PKC blocks Ca2+ oscillation and oscillatory translocation
of Ca2+-dependent PKC. J Biol Chem 279: 2254-2261,
2004
- Taniguchi T, Sumida M, Hiraoka S, Tomoo K, Kakehi T, Minoura K,
Sugiyama S, Inaka K, Ishida T, Saito N, Tanaka C: Effects of different
anti-tau antibodies on tau fibrillogenesis: RTA-1 and RTA-2 counteract
tau aggregation. FEBS Lett 579: 1399-1404, 2005
- Fukunaga-Takenaka R, Shirai Y, Yagi K, Adachi N, Sakai N, Merino
E, Merida I, Saito N: Importance of chroman ring and tyrosine phosphorylation
in the subtype-specific translocation and activation of diacylglycerol
kinase alpha by D-alpha-tocophenol. Genes Cells 10: 311-319,
2005
- Seki T, Matsubayashi H, Amano T, Shirai Y, Saito N, Sakai N: Phosphorylation
of PKC activation loop plays an important role in receptor-mediated
translocation of PKC. Genes Cells 10: 225-239, 2005
- Matsuo A, Bellier JP, Hisano T, Aimi Y, Yasuhara O, Tooyama I, Saito
N, Kimura H: Rat choline acetyltransferase of the peripheral type
differs from that of the common type in intracellular translocation.
Neurochem Int 46: 423-433, 2005
- Hayashi S, Ueyama T, Kajimoto T, Yagi K, Kohmura E, Saito N: Involvement
of γPKC in estrogen-induced neuroprotection on focal brain ischemia
through G protein-coupled estrogen receptor. J Neurochem 93:
883-891, 2005
- Adachi N, Oyasu M, Taniguchi T, Yamaguchi Y, Takenaka R, Shirai
Y, Saito N: Immunocytochemical localization of a neuron-specific diacylglycerol
kinase beta and gamma in the developing rat brain. Mol Brain Res
139: 288-299, 2005
- Ueyama T, Eto M, Kami K, Tatsuno T, Kobayashi T, Shirai Y, Lennartz
MR, Takeya R, Sumimoto H, Saito N: Isoform-specific membrane targeting
mechanism of Rac during Fc gammaR-mediated phagocytosis: positive
charge-dependent and independent targeting mechanism of Rac to the
phagosome. J Immunol 175: 2381-2390, 2005
- Abdel-Raheem IT, Hide I, Yanase Y, Shigemoto-Mogami Y, Sakai N,
Shirai Y, Saito N, Hamada FM, El-Mahdy NA, Elsisy Ael-D, Sokar SS,
Nakata Y: Protein kinase C-alpha mediates TNF release process in RBL-2H3
mast cells. Br J Pharmacol 145: 415-423, 2005
ꎓ¡@ŽÀ@i(à)“Œ‹ž“sˆãŠwŒ¤‹†‹@\E“Œ‹ž“s_Œo‰ÈŠw‘‡Œ¤‹†Šj
- Tamura T, Chiang
AS, Ito N, Liu HP, Horiuchi J, Tully T, Saitoe M: Aging specifically impairs
amnesiac-dependent memory in Drosophila.
Neuron 40: 1003-1011, 2003
- Saitoe M, Tamura
T, Horiuchi J, Ito N: Identification of the memory component that decays with
age in Drosophila. Jpn J Neuropsychopharmacol 24: 231-237,
2004
- Xia S, Miyashita
T, Fu T-G, Lin W-Y, Wu C-L, Pyzocha L, Lin I-R, Saitoe M, Tully T, Chiang A-S:
NMDA receptors mediate olfactory learning and memory in Drosophila. Curr Biol
15: 603-615, 2005
âV“¡@N•F@iŒQ”n‘åŠwE‘åŠw‰@ˆãŠwŒnŒ¤‹†‰Èj
- Saito Y, Isa T: Local excitatory network and NMDA receptor activation generate a
synchronous and bursting command from the superior colliculus. J Neurosci 23: 5854-5864, 2003
- Takazawa T, Saito
Y, Tsuzuki K, Ozawa S: Membrane and firing properties of glutamatergic and
GABAergic neurons in the rat medial vestibular nucleus. J Neurophysiol 92: 3106-3120, 2004
- Saito Y, Isa T: Laminar specific distribution of lateral excitatory connections in the
rat superior colliculus. J Neurophysiol 92: 3500-3510, 2004
âˆä ‹Mb@iŒQ”n‘åŠwE‘åŠw‰@ˆãŠwŒnŒ¤‹†‰Èj
- Sakai T, Tamura T, Kitamoto T,
Kidokoro Y: A clock gene, period,
plays a key role in long-term memory formation in Drosophila. Proc Natl Acad
Sci USA101: 16058-16063, 2004
- Hou J, Kuromi H, Fukasawa Y, Ueno
K, Sakai T, Kidokoro Y: Repetitive exposures to nicotine induce a
hyper-responsiveness via the cAMP/PKA/CREB signal pathway in Drosophila. J Neurobiol 60: 249-261, 2004
葺@ŒšŽi@iVŠƒ‘åŠwE”]Œ¤‹†Šj
- Tanaka J, Nakagawa S, Kushiya E, Yamasaki M, Fukaya M, Iwanaga T,
Simon MI, Sakimura K, Kano M, Watanabe M: Gq protein alpha subunits
Galphaq and Galpha11 are localized at postsynaptic extra-junctional
membrane of cerebellar Purkinje cells and hippocampal pyramidal cells.
Eur J Neurosci 12: 781-792, 2000
- Minami T, Okuda-Ashitaka E, Mori H, Sakimura K, Watanabe M, Mishina
M, Ito S: Characterization of nociceptin/orphanin FQ-induced pain
responses in conscious mice: neonatal capsaicin treatment and N-methyl-D-aspartate
receptor GluRε subunit knockout mice. Neuroscience 97:
133-142, 2000
- Yamakura T, Sakimura K, Shimoji K: N-methyl-D-aspartate receptor
channel block by meperidine is dependent on extracellular pH. Anesth
Analg 90: 928-932, 2000
- Yamakura T, Sakimura K, Shimoji K: The stereoselective effects of
ketamine isomers on heteromeric N-methyl-D-aspartate receptor
channels. Anesth Analg 91: 225-229, 2000
- Ito I, Kawakami R, Sakimura K, Mishina M, Sugiyama H: Input-specific
targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal
neuron synapses. Neuropharmacology 39: 943-951, 2000
- Kitayama K, Abe M, Kakizaki T, Honma D, Natsume R, Fukaya M, Watanabe
M, Miyazaki J, Mishina M, Sakimura K: Purkinje cell-specific and inducible
gene recombination system generated from C57BL/6 mouse ES cells. Biochem
Biophys Res Commun 281: 1134-1140, 2001
- Minami T, Matsumura S, Okuda-Ashitaka E, Shimamoto K, Sakimura K,
Mishina M, Mori H, Ito S: Characterization of the glutamatergic system
for induction and maintenance of allodynia. Brain Res 895:
178-185, 2001
- Yamazaki M, Fukaya M, Abe M, Ikeno K, Kakizaki T, Watanabe M, Sakimura
K: Differential palmitoylation of two mouse glutamate receptor interacting
protein 1 forms with different N-terminal sequences. Neurosci Lett
304: 81-84, 2001
- Yamada K, Fukaya M, Shimizu H, Sakimura K, Watanabe M: NMDA receptor
subunits GluR ε1, GluR ε3 and GluR ζ1 are enriched
at the mossy fibre-granule cell synapse in the adult mouse cerebellum.
Eur J Neurosci 13: 2025-2036, 2001
- Takeuchi T, Kiyama Y, Nakamura K, Tsujita M, Matsuda I, Mori H,
Munemoto Y, Kuriyama H, Natsume R, Sakimura K, Mishina M: Roles of
the glutamate receptor epsilon2 and delta2 subunits in the potentiation
and prepulse inhibition of the acoustic startle reflex. Eur J Neurosci
14: 153-160, 2001
- Ikeno K, Yamakura T, Yamazaki M, Sakimura K: The Lurcher mutation
reveals Ca2+ permeability and PKC modification of the GluRδ
channels. Neurosci Res 41: 193-200, 2001
- Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K,
Mishina M, Hashikawa T, Konnerth A, Watanabe M, Kano M: Roles of glutamate
receptor delta 2 subunit (GluRdelta 2) and metabotropic glutamate
receptor subtype 1 (mGluR1) in climbing fiber synapse elimination
during postnatal cerebellar development. J Neurosci 21: 9701-9712,
2001
- Ichikawa R, Miyazaki T, Kano M, Hashikawa T, Tatsumi H, Sakimura
K, Mishina M, Inoue Y, Watanabe M: Distal extension of climbing fiber
territory and multiple innervation caused by aberrant wiring to adjacent
spiny branchlets in cerebellar Purkinje cells lacking glutamate receptor
delta 2. J Neurosci 22: 8487-8503, 2002
²’|@Lˆê˜Y@iŽ©‘R‰ÈŠwŒ¤‹†‹@\E¶—ŠwŒ¤‹†Šj
- Satake S, Saitow
F, Rusakov D, Konishi S: AMPA receptor-mediated presynaptic inhibition at cerebellar
GABAergic synapses: a characterization of molecular mechanisms. Eur J Neurosci 19: 2464-2474, 2004
‘]—Ç@ˆê˜Y@i“Œ–k‘åŠw¥‘åŠw‰@ˆãŠwŒnŒ¤‹†‰Èj
- Qiu
Q, Sora I, Ren K, Uhl GR, Dubner R: Enhanced delta-opioid receptor-mediated
antinociception in mu-opioid receptor-deficient mice. Eur J Pharmacol 387: 163-169, 2000
- Hosohata
Y, Vanderah TW, Burkey TH, Ossipov MH, Kovelowski CJ, Bian D, Sora I, Uhl GR,
Zhang X, Rice KC, Roeske WR, Hruby VJ, Yamamura HI, Porreca F: Delta opioid
receptor agonists produce antinociception and [35S]GTP gammaS
binding in mu-opioid receptor knock-out mice. Eur J Pharmacol 388: 241-248, 2000
- LaBuda
CJ, Sora I, Uhl GR, Fuchs PN: Stress-induced analgesia in mu-opioid receptor
knockout mice reveals normal function of the delta-opioid receptor system. Brain Res 869: 1-5, 2000
- Uhl
GR, Li S, Takahashi N, Itokawa K, Lin Z, Hazama M, Sora I: The VMAT2 gene in
mice and humans:amphetamine responses, locomotion, cardiac arrhythmias, aging,
and vulnerability to dopaminergic toxins. FASEB
J 14: 2459-2465, 2000
- Wisor
JP, Nishino S, Sora I, Uhl GR, Mignot E, Edgar DM: Dopaminergic role in
stimulant-induced wakefulness. J
Neurosci 21: 1787-1794, 2001
- Hall
FS, Sora I, Uhl GR: Ethanol consumption and reward are decreased in mu-opiate
receptor knockout mice. Psychopharmacology
154: 43-49, 2001
- Sora I, Elmer G, Funada M, Pieper J, Li XF, Hall FS, Uhl
GR: Mu opiate receptor gene dose effects on different morphine actions.
evidence for differential in vivo mu
receptor reserve. Neuropsychopharmacology
25: 41-54, 2001
- Sora
I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy
DL, Uhl GR: Molecular mechanisms of cocaine reward: combined dopamine and
serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci USA 98: 5300-5305, 2001
- Yamamoto
H, Karasawa J, Sagi N, Takahashi S, Horikomi K, Okuyama S, Nukada T, Sora I,
Yamamoto T: Multiple pathways of sigma1 receptor ligand uptakes into primary
cultured neuronal cells. Eur J Pharmacol
425: 1-9, 2001
- Yuyama
K, Yamamoto H, Nakamura K, Kato T, Sora I, Yamamoto T: Resistance of PC12 cells
against nitric oxide (NO)-induced toxicity in long-term cultureFimplication
of neuronal NO synthase expression. Neurosci
Lett 309: 169-172, 2001
- Persico
AM, Mengual E, Moessner R, Hall FS, Revay RS, Sora I, Arellano J, DeFelipe J,
Giménez-Amaya JM, Conciatori M, Marino R, Baldi A, Cabib S, Pascucci T, Uhl GR,
Murphy DL, Lesch KP, Keller F: Barrel pattern formation requires serotonin
uptake by thalamocortical afferents, and not vesicular monoamine release. J Neurosci 21: 6862-6873, 2001
- Zhou Y, Spangler R, Schlussman SD, Yuferov VP, Sora I, Ho
A, Uhl GR, Kreek MJ: Effects of acute "binge" cocaine on
preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotrophin- releasing
hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal
axis of mu-opioid receptor knockout mice. Synapse
45: 220-229, 2002
- Mizoguchi H, Wu HE, Narita M, Hall FS, Sora I, Uhl GR,
Nagase H, Tseng LF: Antagonistic property of buprenorphine for putative
epsilon-opioid receptor-mediated G-protein activation by beta-endorphin in
pons/medulla of the mu-opioid receptor knockout mouse. Neuroscience 115: 715-721, 2002
- Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, Murphy
DL, Uhl GR: Cocaine mechanisms enhanced cocaine, fluoxetine and nisoxetine
place preferences following monoamine transporter deletions. Neuroscience 115: 153-161, 2002
- Karasawa J, Yamamoto H, Yamamoto T, Sagi N, Horikomi K,
Sora I: MS-377, a selective sigma receptor ligand, indirectly blocks the action
of PCP in the N-methyl-D-aspartate receptor ion-channel complex in primary
cultured rat neuronal cells. Life Sci
70: 1631-1642, 2002
- Ikeda
K, Kobayashi T, Kumanishi T, Yano R, Sora I, Niki H: Molecular mechanisms of
analgesia induced by opioids and ethanol: is the GIRK channel one of the keys? Neurosci Res 44: 121-131, 2002
- Uhl
GR, Hall FS, Sora I: Cocaine, reward, movement and monoamine transporters. Mol Psychiatry 7: 21-26, 2002
- Mizoguchi H, Tseng LF, Suzuki T, Sora I, Narita M: Differential
mechanism of G-protein activation induced by endogenous mu-opioid peptides,
endomorphin and beta-endorphin. Jpn J Pharmacol
89: 229-234, 2002
- Hall FS, Sora I, Uhl GR: Sex-dependent
modulation of ethanol consumption in vesicular monoamine transporter 2 (VMAT2)
and dopamine transporter (DAT) knockout mice. Neuropsychopharmacology 28: 620-628, 2003
- Hall FS, Li XF, Goeb M, Roff R, Hoggatt H, Sora I, Uhl GR:
Congenic C57BL/6 mu opiate receptor (MOR) knockout mice: baseline and opiate
effects. Genes Brain
Behav 2: 114-121, 2003
- Yuyama
K, Yamamoto H, Nakamura K, Nrshizaki I, Yamakuni T, Si-Young Song, Sora I,
Nagatsu T, Yamamoto T: Overexpression of V-1 prevents NO-induced cell death:
involvement of enhanced tetrahydrobiopterin (BH4) biosynthesis. J Neurosci Res 72: 716-725, 2003
- Yuyama K, Yamamoto H, Nishizaki I, Kato T, Sora I,
Yamamoto T: Caspase-independent cell death by low concentrations of nitric
oxide (NO) in PC12 cellsFinvolvement
of the inhibition of cytochrome C oxidase and the production of reactive oxygen
species (ROS) in mitochondria. J
Neurosci Res 73: 351-363, 2003
- Itokawa M, Arai M, Kato S, Ogata Y, Furukawa A, Haga S,
Ujike H, Sora I, Ikeda K, Yoshikawa T: Association between a novel polumorphism
in the promoter region of the neuropeptide Y gene and schizophrenia in humans. Neurosci Lett 347: 202-204, 2003
- Ujike H, Harano M, Inada T, Yamada M, Komiyama T, Sekine
Y, Sora I, Iyo M, Katsu T, Nomura A, Nakata K, Ozaki N: Nine-or fewer repeat
alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk
factor for prolonged methamphetamine psychosis. Pharmacogenomics J 3: 242-247, 2003
- Mizoguchi H, Wu HE, Narita M, Sora I, Hall FS, Uhl GR,
Loh HH, Nigase H, Tseng F: Lack of the mu-opioid receptor-mediated G-protein
activation in the mouse spinal cord lacking exon1 and exon 2 & 3 of MOR-1
gene. J Pharmacol Sci 93: 423-429, 2003
- Murphy
DL, Uhl GR, Holmes A, Ren-Patterson R, Hall FS, Sora I, Detera-Wadleigh S,
Lesch KP: Experimental gene interaction studies with SERT mutant mice as models
for human polygenic and epistatic traits and disorders. Genes Brain Behav 2: 350-364, 2003
- HallFS, GoebM, Li XF, SoraI, Uhl GR: Mu opioid
receptor knockout mice display reduced cocaine conditioned place preference but
enhanced sensitization of cocaine-induced locomotion. Mol Brain Res 121: 123-130, 2004
- Koizumi H, Hashimoto K, Kumakiri C, Shimizu E, Sekine Y, Ozaki
N, Inada T, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Takei N, Iyo M: Association
between the glutathione S-transferase M1 gene deletion and female
methamphetamine abusers. Am J Med Genet 126B: 43-45, 2004
- Yamamoto T, Nishizaki I, Nukada T, Kamegaya F, Furuya S,
Hirabayashi Y, Ikeda K, Hata H, Kobayashi H, Sora I, Yamamoto H: Functional
identification of ASCT1 neutral amino acid transporter as the predominant system for the uptake of L-serine in rat
neurons in primaryculture.Neurosci Res 49:
101-111, 2004
- Mansikka
H, Zhao C, Sheth RN, Sora I, Uhl GR, Raja SN: Nerve injury induces a tonic bilateral mu-opioid receptor-mediated
inhibitory effect on mechanical allodynia in mice. Anesthesiology 100: 912-921, 2004
- Arai
M, Itokawa M, Yamada K, Toyota T, Arai M, Haga S, Ujike H, Sora I, Ikeda K,
Yoshikawa T: Association of neural cell adhesion molecule 1gene polymorphisms
with bipolar affective disorder in Japanese individuals. Biol Psychiatry 55: 804-810, 2004
- Kockelkorn TT, Arai M, Matsumoto H, Fukuda N, Yamada K,
Minabe Y, Toyota T, Ujike H, Sora I, Mori N, Yoshikawa T, Itokawa M: Association
study of polymorphisms in the 5' upstream region of human DISC1 gene with
schizophrenia. Neurosci Lett 368:
41-45, 2004
- Shen H, Hagino Y, Kobayashi H, Shinohara-Tanaka K, Ikeda
K, Yamamoto H, Yamamoto T, Lesch KP, Murphy DL, Hall FS, Uhl GR, Sora I: Regional
differences in extracellular dopamine and serotonin assessed by in vivo
microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology
29: 1790-1799, 2004
- Ide S, Minami M, Satoh M, Uhl GR, Sora I, Ikeda K: Buprenorphine
antinociception is abolished, but naloxone-sensitive reward is retained, in
mu-opioid receptor knockout mice. Neuropsychopharmacology
29: 1656-1663, 2004
- Yamamoto
H, Imai K, Takamatsu Y, Kamegaya E, Hara Y, Shimada K, Yamamoto T, Shen HW,
Hagino Y, Kobayashi H, Ide S, Sora I, Koga H, Ikeda K: Changes in expression of
the mouse homologues of KIAA genes after subchronic methamphetamine treatment. Ann NY Acad Sci 1025: 92-101, 2004
- Han
W, Ide S,Sora I, Yamamoto H, Ikeda K: A possible genetic mechanism
underlying individual and interstrain differences in opioid actions: focus on
the mu opioid receptor gene. Ann NY Acad
Sci 1025: 370-375, 2004
- Ide
S, Kobayashi H, Tanaka K, Ujike H, Sekine Y, Ozaki N, Inada T, Harano M,
Komiyama T, Yamada M, Iyo M, Ikeda K, Sora I: Gene polymorphisms of the mu
opioid receptor in methamphetamineabusers. Ann
NY Acad Sci 1025: 316-324, 2004
- Hironaka
N, Ikeda K, Sora I, Uhl GR, Niki H: Food-reinforced operant behavior in
dopamine transporter knockout mice: enhanced resistance to extinction. Ann NY Acad Sci 1025: 140-145, 2004
- Kobayashi
H, Ide S, Hasegawa J, Ujike H, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama
T, Yamada M, Iyo M, Shen HW, Ikeda K, Sora I: Study of association between
alfa-synuclein gene polymorphism and methamphetamine psychosis/ dependence. Ann NY Acad Sci 1025: 325-334, 2004
- Harano
M, Uchimura N, Abe H, Ishibashi M, Iida N, YanagimotoK, Tanaka T,
Maeda H, SoraI, Iyo M,
Komiyama T, Yamada M, Sekine Y, Inada T, Ozaki N, Ujike H: A polymorphism of
DRD2 gene and brain atrophy in methamphetamine psychosis. Ann
NY Acad Sci 1025: 307-315, 2004
- InadaT, IijimaY, UchidaN, MaedaT, IwashitaS, OzakiN, HaranoM, KomiyamaT, YamadaM, SekineY, IyoM,
SoraI, Ujike H: No
association between the type 1 sigma receptor gene polymorphisms and
methamphetamine abuse in the Japanese population: A
collaborative study by the Japanese Genetics Initiative for Drug Abuse (JGIDA).
Ann NY Acad Sci 1025: 27-33, 2004
- IwataN, InadaT, HaranoM, KomiyamaT, YamadaM, SekineY, IyoM, SoraI, UjikeH,
OzakiN: No association between the
candidate genes of t-PA/Plasminogen system and Japanese methamphetamine related
disorder: A collaborative study by the Japanese Genetics
Initiative for Drug Abuse (JGIDA). Ann
NY Acad Sci 1025: 34-38, 2004
- Numachi
Y, Yoshida S, Yamashita M, Fujiyama K, Naka M, Matsuoka H, Sato M, Sora I: Psychostimulant
alters expression of DNA methyltransferase mRNA in the rat brain. Ann NY Acad Sci 1025: 102-109, 2004
- Hall
FS, Sora I, Drgonova J, Li XF, Goeb M, Uhl GR: Molecular mechanisms underlying the rewarding
effects of cocaine. Ann NY Acad Sci
1025: 47-56, 2004
- Morita
Y, Ujike H, Tanaka Y, Uchida N, Nomura A, Ohtani K, Kishimoto M, Morio A,
Imamura T, Sakai A, Inada T, Harano M, Komiyama T, Yamada M, Sekine Y, Iwata N,
Iyo M, Sora I, Ozaki N, Kuroda S: A nonsynonymous polymorphism in the human
fatty acid amide hydrolase gene did not associate with either methamphetamine
dependence or schizophrenia. Neurosci
Lett 376: 182-187, 2005
- Nishiyama T, Ikeda M, Iwata N, Suzuki T, Kitajima T,
Yamanouchi Y, Sekine Y, Iyo M, Harano M, Komiyama T, Yamada M, Sora I, Ujike H,
Inada T, Furukawa T, Ozaki N: Haplotype association between GABA(A) receptor
gamma2 subunit gene (GABRG2) and
methamphetamine use disorder. Pharmacogenomics J 5:89-95,
2005
- Yamamoto H, Imai K, Takamatsu Y, Kamegaya E, Kishida M,
Hagino Y, Hara Y, Shimada K, Yamamoto T, Sora I, Koga H, Ikeda K: Methamphetamine
modulation of gene expression in the brain: analysis using customized cDNA
microarray system with the mouse homologues of KIAA genes. Mol Brain Res 137:
40-46, 2005
- Morita
Y, Ujike H, Tanaka Y, Uchida N, Nomura A, Ohtani K, Kishimoto M, Morio A, Inada
T, Harano M, Komiyama T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N: The
X-box binding protein 1 (XBP1) gene is not associated with methamphetamine
dependence. Neurosci Lett 383:
194-198, 2005
- Ide
S, Kobayashi H, Tanaka K, Ujike H, Ozaki N, Sekine Y, Inada T, Harano M,
Komiyama T, Yamada M, Iyo M, Iwata N, Shen H, Iwahashi K, Itokawa M, Minami M,
Satoh M, Ikeda K, Sora I: Gene polymorphisms of the mu opioid receptor in
methamphetamine abusers. Pharmacogenomics
Jin press
- Hashimoto
T, Hashimoto K, Matsuzawa D, Shimizu E, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M,
Sora I, Ujike H, Iyo M: A functional
glutathione-S-transferase P1 polymorphism is associated with methamphetamine-induced
psychosis in Japanese population. Am J
Med GenetB Neuropsychiatr Genet 135: 5-9, 2005
- Suzuki
A, Nakamura K, Sekine Y, Minabe Y, Takei N, Suzuki K, Iwata Y, Kawai M,
Takebayashi K, Iyo M, Ozaki N, Inada T, Iwata N, Harano M, Komiyama T, Yamada
M, Sora I, Ujike H, Mori N: An association study between COMT gene polymorphism
and methamphetamine psychotic disorder. Psychiat
Genet in press
- Ohgake
S, Hashimoto K, Shimizu E, Koizumi H, Okamura N, Koike K, Matsuzawa D, Sekine
Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H,
Shirayama Y, Iyo M: Functional polymorphism of the NQO2 gene is associated with
methamphetamine psychosis.Addict Biol 10: 145-148, 2005
- Ide
S, Han W, Kasai S, Hata H, Sora I, Ikeda K: Characterization of the 3f
untranslated region of the human mu-opioid receptor (MOR-1) mRNA. Genein press
“c’†@G˜a@i‘åã‘åŠwEˆãŠwŒnŒ¤‹†‰Èj
- Tanaka
H, Shan W, Phillips GR, Arndt K, Bozdagi O, Shapiro L, Huntley GW, Benson DL,
Colman DR: Molecular modification of N-cadherin in response to synaptic
activity. Neuron25: 93-107, 2000
- Shan
WS, Tanaka H, Phillips GR, Arndt K, Yoshida M, Colman DR, Shapiro L: Functional
cis-heterodimers of N- and R-cadherins. J
Cell Biol 148: 579-90, 2000
- Taguchi
A, Blood DC, del Toro G, Canet A, Lee DC, Qu W, Tanji N, Lu Y, Lalla E, Fu C,
Hofmann MA, Kislinger T, Ingram M, Lu A, Tanaka H, Hori O, Ogawa S, Stern DM,
Schmidt AM: Blockade of RAGE-amphoterin signalling suppresses tumour growth and
metastases. Nature 405: 354-60, 2000
- Bozdagi
O, Shan W, Tanaka H, Benson DL, Huntley GW: Increasing numbers of synaptic
puncta during late-phase LTP: N-cadherin is synthesized, recruited to synaptic
sites, and required for potentiation. Neuron
28: 245-59, 2000
- Phillips
GR, Huang JK, Wang Y, Tanaka H, Shapiro L, Zhang W, Shan WS, Arndt K, Frank M,
Gordon RE, Gawinowicz MA, Zhao Y, Colman DR: The presynaptic particle web:
ultrastructure, composition, dissolution, and reconstitution. Neuron 32: 63-77, 2001
- Gan Y,
Taira E, Irie Y, Tanaka H, Ichikawa H, Kumamaru E, Miki N: Amida predominantly
expressed and developmentally regulated in rat testis. Biochem Biophys Res Commun 288: 407-12, 2001
- Okumura
S, Muraoka O, Tsukamoto Y, Tanaka H, Kohama K, Miki N, Taira E: Involvement of
gicerin in the extension of microvilli. Exp
Cell Res 271: 269-76, 2001
- Phillips
GR, Tanaka H (equal contribution), Frank M, Elste A, Fidler L, Benson DL,
Colman DR: Gamma-protocadherins are targeted to subsets of synapses and
intracellular organelles in neurons. J
Neurosci 23: 5096-104, 2003
- Do E,
Taira E, Irie Y, Gan Y, Tanaka H, Kuo CH, Miki N: Molecular cloning and
characterization of rKAB1, which interacts with KARP-1, localizes in the
nucleus and protects cells against oxidative death. Mol Cell Biochem 248: 77-83, 2003
“c’[ r‰p@i‹à‘ò‘åŠwEˆãŠwŒnŒ¤‹†‰Èj
- Tabata T, Kano M:
Calcium-dependence of native metabotropic glutamate receptor signalling in
central neurons. Mol Neurobiol 29:
261-270, 2004
- Sato M, Tabata T, Hashimoto
K, Nakamura K, Nakao K, Katsuki M, Kitano J, Moriyoshi K, Kano M, Nakanishi S:
Altered agonist sensitivity and desensitization of neuronal mGluR1 responses in
knock-in mice by a single amino acid substitution at the PKC phosphorylation
site. Eur J Neurosci 20: 947-955,
2004
- Tabata T, Araishi K,
Hashimoto K, Hashimotodani Y, Van der Putten H, Bettler B, Kano M: Ca2+
activity at GABAB receptor constitutively promotes metabotropic
glutamate signaling in the absence of GABA.
Proc Natl Acad Sci USA 101: 16952-16957, 2004
- Tabata T, Haruki S, Nakayama
H, Kano M: GABAergic activation of an inwardly rectifying K+ current
in mouse cerebellar Purkinje cells. J
Physiol 563: 443-457, 2005
Žè’Ë@“O@i“Œ‹ž‘åŠwEˆã‰ÈŠwŒ¤‹†Šj
- Nakazawa T, Watabe AM, Tezuka
T , Yoshida Y, Yokoyama K, Umemori H, Inoue A, Okabe S, Manabe T, Yamamoto T:
p250GAP, a novel brain-enriched GTPase-activating protein for Rho family
GTPases, is involved in the N-methyl-D-aspartate
receptor signaling. Mol Biol Cell
14: 2921-2934, 2003
- Taniguchi S, Liu H, Nakazawa
T, Yokoyama K, Tezuka T ,Yamamoto T: p250GAP, a neural RhoGAP protein, is
associated with and phosphorylated by Fyn. Biochem
Biophys Res Commun 306: 151-155, 2003
- Watanabe Y, Song T, Sugimoto
K, Horii M, Araki N, Tokumitsu H, Tezuka T, Yamamoto T, Tokuda M: Post-synaptic
density-95 promotes calcium/calmodulin-dependent protein kinase II-mediated
Ser(847) phosphorylation of neuronal nitric oxide synthase. BiochemJ 372: 465-471, 2003
- Suetsugu S, Tezuka
T, Morimura T, Hattori M, Mikoshiba K, Yamamoto T, Takenawa T: Regulation of
actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1. Biochem J 384:
1-8, 2004
- Kawa S, Fujimoto
J, Tezuka T, Nakazawa T, Yamamoto T: Involvement of BREK, a serine/threonine
kinase enriched in brain, in NGF signaling. Genes Cells 9: 219-232, 2004
- Kim M,
Tezuka T, Tanaka K, Yamamoto T: Cbl-c suppresses v-Src-induced transformation
through ubiquitin-dependent protein degradation. Oncogene
23: 1645-1655, 2004
- Goto
J, Tezuka T, Nakazawa T, Tsukamoto N, Nakamura T, Ajima R, Yokoyama K, Ohta T,
Ohki M, Yamamoto T: Altered gene expression in the adult brain of fyn-deficient mice. Cell Mol Neurobiol 24: 149-159, 2004
- Nishida K, Yamasaki S, Ito Y,
Kabu K, Hattori T, Tezuka T, Nishizumi H, Kitamura D, Goitsuka R, Geha RS,
Yamamoto T, Yagi T, Hirano T: FcRI-mediated mast cell degranulation requires
calcium-independent microtubule-dependent translocation of granules to the
plasma membrane. J Cell Biol 170: 115-126, 2005
’©’·@Œ[‘¢@i‘åã‘åŠwE”÷¶•¨•aŒ¤‹†Šj
- Yamashita M,
Kamitani W, Yanai H, Ohtaki N, Watanabe Y, Lee B-J, Tsuji S, Ikuta K, Tomonaga
K: Persistent Borna disease virus infection confers instability of HSP70 mRNA
in glial cells during heat stress. J
Virol 79: 2033-2041, 2005
- Hazama K, Miyagawa
S, Yamamoto A, Kubo T, Miyazawa T, Tomonaga K, Watanabe R, Okumura M, Matsuda
H, Shirakura R: The effect of expression of complement regulatory protein on
pig endothelial cells to pig endogenous retrovirus lyses by human sera. Transplant Proc 37: 503-505, 2005
- Miyagawa S,
Nakatsu S, Nakagawa T, Kondo A, Matsunami K, Hazama K, Yamada J, Tomonaga K,
Miyazawa T, Shirakura R: Prevention of PERV infections in pig to human
xenotransplantation by the RNA interference silences gene. J Biochem 137: 503-508, 2005
- Matsunaga H,
Tanaka S, Sasao F, Nishino Y, Takeda M, Tomonaga K, Ikuta K, Amino N: Detection
of antibodies against Borna disease virus by a radioligand assay in patients
with various psychiatric disorders. Clin
Diagn Lab Immunol 12: 671-676, 2005
ª–{@’mŒÈ@i‰ªè‘—§‹¤“¯Œ¤‹†‹@\E¶—ŠwŒ¤‹†Šj
- Takahashi N, Kishimoto T, Nemoto T,
Kadowaki T, Kasai H: Fusion pore dynamics and insulin granule exocytosis in the
pancreatic islet. Science297: 1349-1352, 2002
- Noda M, Yamashita S, Takahashi N, Eto
K, Shen L, Izumi K, Daniel S, Tsubamoto Y, Nemoto T, Iino M, Kasai H, Geoffrey
WG, Sharp GW, Kadowaki T: Switch to anaerobic glucose metabolism with NADH
accumulation in the β-cell model of mitochondrial diabetes: Characteristics of
βHC9 cells deficient in mitochondrial DNA transcription. J Biol Chem277: 41817-41826,
2002
- Takahashi N, Nemoto T, Kimura R,
Tachikawa A, Miwa A, Okado H, Miyashita Y, Iino M, Kadowaki T, Kasai H: Two-photon
excitation imaging of pancreatic islet with various fluorescent probes.Diabetes
S1: 25-28, 2002
ª–{@N•v@i“Œ–k‘åŠwE‘åŠw‰@ˆãŠwŒnŒ¤‹†‰Èj
- Sakakibara T, Nemoto Y, Nukiwa T, Takeshima H: Identification and
characterization of a novel Rho GTPase activating protein implicated
in receptor-mediated endocytosis. FEBS Lett 566:
294-300, 2004
”¨@—T@i“Œ‹žˆã‰ÈŽ•‰È‘åŠwE‘åŠw‰@ˆãŽ•Šw‘‡Œ¤‹†j
- Yao I, Ohtsuka T,
Kawabe H, Matsuura Y, Takai Y, Hata Y: Association of membrane-associated
guanylate kinase-interacting protein-1 with Raf-1. Biochem Biophys Res Commun 270: 538-542, 2000
- Deguchi M, Iizuka
T, Hata Y, Nishimura W, Hirao K, Yao I, Kawabe H, Takai Y: PAPIN: a novel
multiple PDZ protein interacting with neural plakophilin-related
armadillo-repeat protein/delta-catenin and p0071. J Biol Chem 275: 29875-29880, 2000
- Nishimura W,
Iizuka T, Hirabayashi S, Tanaka N, Hata Y: Localization of BAP1/MAGI-1 at
adherens junctions in NRK cells: the polarized targeting mediated by the
carboxyl-terminal PDZ domains. J Cell
Physiol 185: 358-365, 2000
- Nishimura W, Yao
I, Iida J, Tanaka N, Hata Y: Interaction of synaptic scaffolding molecule
(S-SCAM) and beta-catenin. J Neurosci 22:
757-765, 2002
”©@‹`˜Y@i‘åã‘åŠw‘åŠw‰@¥ˆãŠwŒnŒ¤‹†‰Èj
- Hata Y, Ohshima M,
Ichisaka S, Wakita M, Fukuda M, Tsumoto T: BDNF expands ocular dominance
columns in visual cortex in monocularly deprived and non-deprived kittens, but
does not in adult cats. J Neurosci
20: RC57 (1-5), 2000
- Jiang B-J, Akaneya
Y, Ohshima M, Ichisaka S, Hata Y, Tsumoto T: Brain-derived neurotrophic factor
induces long-lasting potentiation of synaptic transmission in visual cortex in vivo in young rats, but does not in
the adult. Eur J Neurosci 14: 1219-1228,
2001
- Katoh-Semba R,
Takeuchi IK, Inaguma Y, Ichisaka S, Hata Y, Tsumoto T, Iwai M, Mikoshiba K,
Kato K: Induction of brain-derived neurotrophic factors by convulsant drugs in
the rat brain: Involvement of voltage-dependent calcium channels. J Neurochem 77: 71-83, 2001
- Ohshima M, Hata Y,
Ichisaka S, Wakita M, Fukuda M, Kameyama K, Tsumoto T: Chronic, electrical
stimulation of afferents from one eye changes ocular dominance of visual
cortical neurons in kittens. J
Neurophysiol 88: 2147-2151, 2002
[àV@—LŒá@iŽ©‘R‰ÈŠwŒ¤‹†‹@\E¶—ŠwŒ¤‹†Šj
- Kulik A, Nakadate
K, Hagiwara A, Fukazawa Y, Lujan R, Saito H, Suzuki N, Futatsugi A, Mikoshiba
K, Frotscher M, Shigemoto R: Immunocytochemical localization of the alpha 1A
subunit of the P/Q-type calcium channel in the rat cerebellum. Eur J Neurosci 19: 2169-2178, 2004
- Sato T, Fukazawa
Y, Ohta Y, Iguchi T: Involvement of growth factors in induction of persistent
proliferation of vaginal epithelium of mice exposed neonatally to
diethylstilbestrol. Reprod Toxicol
19: 43-51, 2004
- Inoue
K, Fukazawa Y, Ogura A, Inokuchi K: Two-dimensional neural activity mapping of
the entire population of hippocampal CA1 pyramidal cells responding to fear
conditioning.Neurosci Res 51: 417-425, 2005
- Hagiwara A,
Fukazawa Y, Deguchi-Tawarada M, Ohtsuka T, Shigemoto R: Differential
distribution of release-related proteins in the hippocampal CA3 area as
revealed by Freeze-fracture replica labeling. J Comp Neurol 489:
195-216, 2005
¼è ‹I@iŽ©‘R‰ÈŠwŒ¤‹†‹@\E¶—ŠwŒ¤‹†Šj
- Sakai N, Tsubokawa H, Matsuzaki M, Kajimoto T, Takahashi E, Ren
Y, Ohmori S, Shirai Y, Matsubayashi H, Chen J, Duman RS, Kasai H,
Saito N: Propagation of γPKC translocation along the dendrites
of Purkinje cell in γPKC-GFP transgenic mice. Genes Cells
9: 945-957, 2004
- Matsuzaki M, Honkura N, Ellis-Davies GCR, Kasai H: Structural basis
of long-term potentiation in single dendritic spines. Nature
429: 761-766, 2004
- Noguchi J, Matsuzaki M, Ellis-Davies GCR, Kasai H: Spine-neck geometry
determines NMDA-receptor dependent Ca2+ signaling in dendrites.
Neuron 46: 609-622, 2005
- Tanaka J, Matsuzaki M, Tarusawa E, Momiyama A, Molnar E, Kasai H,
Shigemoto R: Number and density of AMPA receptors in single synapses
in immature cerebellum. J Neurosci 25: 799-807, 2005
ŽR“c@Ÿ–ç@iH“c‘åŠwEˆãŠw•”j
- Tanaka U, Yamada K, Zhou C-J, Ban N, Shioda S,
Inagaki N: Temporal and spatial profiles of ABCA2-expressing oligodendrocytes
in the developing rat brain. J Comp
Neurol 455: 353-367, 2003
- Yuan H, Yamada K, Inagaki N: Multiminute
oscillations in mouse substantia nigra pars reticulata neurons in vitro. Neurosci Lett 355: 136-140, 2004
- Yuan H, Yamada K, Inagaki N: Glucose sensitivity in
mouse substantia nigra pars reticulata neurons in vitro. Neurosci Lett
355: 173-176, 2004
- Yamada K, Inagaki N: Neuroprotection by KATP
channels. J Mol Cell Cardiol 38:
945-949, 2005
- Wang Y, Yamada K, Tanaka Y, Ishikawa K, Inagaki N: Expression
of ABCA2 protein in human vestibular schwannoma and peripheral nerve. J Neurol Sci 15: 232, 59-63, 2005
“n•”@•¶Žq@i“Œ‹ž‘åŠwEˆã‰ÈŠwŒ¤‹†Šj
- Bando T, Sekine K, Kobayashi S, Watabe AM, Rump A, Tanaka M, Suda Y,
Kato S, Morikawa Y, Manabe T, Miyajima A: Neuronal
leucine-rich repeat protein 4 functions in hippocampus-dependent long-lasting
memory. Mol Cell Biol 25: 4166-4175, 2005
- Nakazawa T, Watabe AM, Tezuka T, Umemori H, Manabe T, Yamamoto T: P250GAP,
A novel Rho GTPase-activating protein, interacts with NMDA receptor. Mol Biol Cell 14: 2921-2934, 2003
- Opazo P, Watabe AM,
Grant SG, O'Dell TJ: Phosphatidylinositol 3-kinase regulates the induction of
long-term potentiation through extracellular signal-related kinase-independent
mechanisms. J Neurosci23: 3679-3688, 2003
- Watabe AM, OfDell TJ: Age-related changes in theta frequency
stimulation-induced long-term potentiation. Neurobiol Aging 24: 267-272, 2003
˜a’†@–¾¶@i•Ÿ“‡Œ§—§ˆã‰È‘åŠwEˆãŠw•”j
- Takeda J, Sato Y,
Kiyosawa H, Mori T, Yokoya S, Irisawa A, Miyata M, Obara K, Fujita T, Suzuki T,
Kasukawa R, Wanaka A: Anti-tumor immunity against CT26 colon tumor in
mice immunized with plasmid DNA encoding beta-galactosidase fused to an
envelope protein of endogenous retrovirus. Cell Immunol204: 11-18, 2000
- Nakajima A, Nakajima F, Shimizu S, Ogasawara A, Wanaka A, Moriya H,
Einhorn TA, Yamazaki M: Spatial and temporal gene expression for fibroblast
growth factor type I receptor (FGFR1) during fracture healing in the rat. Bone 29: 458-466, 2001
- Nikaido T, Yokoya S, Mori T, Hagino S, Iseki K, Zhang Y, Takeuchi M,
Takaki H, Kikuchi S, Wanaka A: Expression of the novel transcription factor
OASIS, which belongs to the CREB/ATF family, in mouse embryo with special
reference to bone development. Histochem
Cell Biol 116: 141-148, 2001
-
Shinoe T, Wanaka A, Nikaido T, Kanazawa K, Shimizu J, Imaizumi K, Kanazawa I:
Upregulation of the pro-apoptotic BH3-only peptide harakiri in spinal neurons
of amyotrophic lateral sclerosis patients. Neurosci
Lett 313: 153-157, 2001
- Hagino S, Iseki K, Mori T, Zhang Y, Hikake T, Yokoya S, Takeuchi M,
Hasimoto H, Kikuchi S, Wanaka A: Slit and glypican-1 mRNAs are coexpressed in
the reactive astrocytes of the injured adult brain. Glia 42: 130-138, 2003
- Zhang Y, Mori T, Iseki K, Hagino S, Takaki H, Takeuchi M, Hikake T, Tase
C, Murakawa M, Yokoya S, Wanaka A: Differential expression of decorin and
biglycan genes during palatogenesis in normal and retinoic acid-treated mice. Dev Dyn 226: 618-626, 2003
- Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, Takagi H, Yokoya S, Wanaka
A: Comparison of expression patterns between CREB family transcription factor
OASIS and proteoglycan core protein genes during murine tooth development. Anat Embryol 206: 373-380, 2003
- Shibaguchi T, Kato J, Abe M, Tamamura Y, Tabata MJ, Liu JG, Iwamoto M,
Wakisaka S, Wanaka A, Kurisu K: Expression and role of Lhx8 in murine tooth
development. Arch Histol Cytol 66:
95-108, 2003
- Hagino S, Iseki K, Mori T, Zhang Y, Sakai N, Yokoya S, Hikake T, Kikuchi
S, Wanaka A: Expression pattern of glypican-1 mRNA after brain injury in mice. Neurosci Lett 349: 29-32, 2003
- Nonaka M, Yoshikawa M, Nishimura F, Yokota H, Kimura H, Hirabayashi H,
Nakase H, Ishizaka S, Wanaka A, Sakaki T: Intraventricular transplantation of
embryonic stem cell-derived neural stem cells in intracerebral hemorrhage rats.
Neurol Res 26: 265-272, 2004
- Mori T, Yuxing Z, Takaki H, Takeuchi M, Iseki K, Hagino S, Kitanaka J,
Takemura M, Misawa H, Ikawa M, Okabe M, Wanaka A: The LIM homeobox gene,
L3/Lhx8, is necessary for proper development of basal forebrain cholinergic
neurons. Eur J Neurosci 19:
3129-3141, 2004
- Kondo S, Murakami T, Tatsumi K, Ogata M, Kanemoto S, Otori K, Iseki K,
Wanaka A, Imaizumi K: OASIS, a CREB/ATF-family member, modulates UPR signalling
in astrocytes. Nat Cell Biol 7:
186-194, 2005
- Tatsumi K, Haga S, Matsuyoshi H, Inoue M, Manabe T, Makinodan M, Wanaka A:
Characterization of cells with proliferative activity after a brain injury. Neurochem Int 46: 381-389, 2005
- Uemura M, Tatsumi K, Matsumoto M, Fujimoto M,
Matsuyama T, Ishikawa M, Iwamoto TA, Mori T, Wanaka A, Fukui H, Fujimura Y:
Localization of ADAMTS13 to the stellate cells of human liver. Blood 106: 922-924, 2005
|