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  1. Inoue M, Mishina M, Ueda H: Enhanced nociception by exogenous and endogenous substance P given into the spinal cord in mice lacking NR2A/ε1, an NMDA receptor subunit. Br J Pharmacol 129: 239-241, 2000


  2. Ito I, Kawakami R, Sakimura K, Mishina M, Sugiyama H: Input-specific targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal neuron synapses. Neuropharmacology 39: 943-951, 2000


  3. Minami T, Okuda-Ashitaka E, Mori H, Sakimura K, Watanabe M, Mishina M, Ito S: Characterization of nociceptin/orphanin FG-induced pain responses in conscious mice: Neonatal capsaicin treatment and N-methyl-D-aspartate receptor GluRε subunit knockout mice. Neuroscience 97: 133-142, 2000


  4. Hironaka K, Umemori H, Tezuka T, Mishina M, Yamamoto T: The protein-tyrosine phosphatase PTPMEG interacts with glutamate receptor δ2 and εsubunits. J Biol Chem 275: 16167-16173, 2000


  5. Matsuda I, Mishina M: Identification of a juxtamembrane segment of the glutamate receptor δ2 subunit required for the plasma membrane localization. Biochem Biophys Res Commun 275: 565-571, 2000


  6. Nakamura K, Manabe, T, Watanabe M, Mamiya T, Ichikawa R, Kiyama Y, Sanbo M, Yagi T, Inoue Y, Nabeshima T, Mori H, Mishina M: Enhancement of hippocampal LTP, reference memory and sensorimotor gating in mutant mice lacking a telencephalon-specific cell adhesion molecule. Eur J Neurosci 13: 179-189, 2001


  7. Nakazawa T, Komai S, Tezuka T, Hisatsune C, Umemori H, Semba K, Mishina M, Manabe T, Yamamoto T: Characterization of Fyn-mediated tyrosine phosphorylation sites on GluRε2 (NR2B) subunit of the N-methyl-D-aspartate receptor. J Biol Chem 276: 693-699, 2001


  8. Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T: Hyperfunction of dopaminergic and serotonergic neural systems in mice lacking NMDA receptor ε1 subunit. J Neurosci 21: 750-757, 2001


  9. Uchino S, Nakamura T, Nakamura K, Nakajima-Iijima S, Mishina M, Kohsaka S, Kudo Y: Real-time two-dimensional visualization of ischemia-induced glutamate release from hippocampal slices. Eur J Neurosci 13: 670-678, 2001


  10. Kishimoto Y, Kawahara S,Mori H,Mishina M, Kirino Y: Long-trace interval eyeblink conditioning is impaired in mutant mice lacking the NMDA receptor subunit ε1. Eur J Neurosci 13: 1221-1227, 2001


  11. Kishimoto Y, Kawahara S, Suzuki M, Mori H, Mishina M, Kirino Y: Classical eyeblink conditioning in glutamate receptor subunit ε2 mutant mice is impaired in the delay paradigm but not in the trace paradigm. Eur J Neurosci 13: 1249-1253, 2001


  12. Kitayama K, Abe M, Kakizaki T, Honma D, Natsume R, Fukaya M, Watanabe M, Miyazaki J, Mishina M, Sakimura K: Purkinje cell-specific and inducible gene recombination system generated from C57BL/6 mouse ES cells. Biochem Biophys Res Commun 281: 1134-1140, 2001


  13. Minami T, Matsumura S, Okuda-Ashitaka E, Shimamoto K, Sakimura K, Mishina M, Mori H, Ito S: Characterization of the glutamatergic system for induction and maintenance of allodynia. Brain Res 895: 178-185, 2001


  14. Takeuchi T, Kiyama Y, Nakamura K, Tsujita M, Matsuda I, Mori H, Munemoto Y, Kuriyama H, Natsume R, Sakimura K, Mishina M: Roles of the glutamate receptor ε2 and δ2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex. Eur J Neurosci 14: 153-160, 2001


  15. Wainai T, Takeuchi T, Seo N, Mishina M: Regulation of acute nociceptive responses by the NMDA receptor GluRε2 subunit. NeuroReport 12: 3165-3172, 2001


  16. Uchino S, Watanabe W, Nakamura T, Shuto S, Kazuta Y, Matsuda A, Nakajima-Iijima S, Kohsaka S, Kudo Y, Mishina M: Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of subtype selectivity of a novel antagonist PPDC. FEBS Lett 506: 117-122, 2001


  17. Kishimoto Y, Kawahara S, Fujimichi R, Mori H, Mishina M, Kirino Y: Impairment of eyeblink conditioning in GluRε2 mutant mice depends on the temporal overlap between conditioned and unconditioned stimuli. Eur J Neurosci 14: 1515-1521, 2001


  18. Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K, Mishina M, Hashikawa T, Konnerth A, Watanabe M, Kano M: Roles of GluRε2 and mGluR1 in climbing fiber synapse elimination during postnatal cerebellar development. J Neurosci 21: 9701-9712, 2001


  19. Takatsuki K, Kawahara S, Mori H, Mishina M, Kirino Y: Scopolamine impairs eyeblink conditioning in the cerebellar LTD-deficient mice. NeuroReport 13: 159-162, 2002


  20. Miyagi Y, Yamashita T, Fukaya M, Sonoda T, Okuno T, Yamada K, Watanabe M, Nagashima Y, Aoki I, Okuda K, Mishina M, Kawamoto S: Delphilin: a novel PDZ- and formin homology-domain containing protein, which synaptically colocalizes and interacts with glutamate receptor ε2 subunit. J Neurosci 22: 803-814, 2002


  21. Haradahira T, Okauchi T, Maeda J, Zhang M-R, Kida T, Kawabe K, Mishina M, Watanabe Y, Suzuki K, Suhara T: A positron-emitter labeled glycineB site antagonist, [11C]L-703,717, preferentially binds to a cerebellar NMDA receptor subtype consisting of GluRε3 subunits in vivo, but not in vitro. Synapse 43: 131-133, 2002


  22. Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T: Lower sensitivity to stress and altered monoaminergic neuronal function in mice lacking the NMDA receptor ε4 subunit. J Neurosci 22: 2335-2342, 2002


  23. Takeuchi T, Nomura T, Tsujita M, Suzuki M, Fuse T, Mori H, Mishina M: Flp recombinase transgenic mice of C57BL/6 strain for conditional gene targeting. Biochem Biophys Res Commun 293: 953-957, 2002


  24. Sakamoto T, Mishina M, Niki H: Mutation of NMDA receptor subunit epsilon 1: Effects on audiogenic-like seizures induced by electrical stimulation of the inferior coliculus in mice. Mol Brain Res 102: 113-117, 2002


  25. Uemura T, Mori H, Mishina M: Isolation and characterization of Golgi apparatus-specific GODZ with the DHHC zinc finger domain. Biochem Biophys Res Commun 296: 492-496, 2002


  26. Ichikawa R, Miyazaki T, Kano M, Hashikawa T, Tatsumi H, Sakimura K, Mishina M, Inoue Y, Watanabe M: Distal extension of climbing fiber territory and multiple innervation caused by aberrant wiring to adjacent spiny branchlets in cerebellar Purkinje cells lacking glutamate receptor GluRδ2. J Neurosci 22: 8487-8503, 2002


  27. Takatsuki K, Kawahara S, Kotani S, Mori H, Mishina M, Kirino Y: Hippocampal damage disrupts eyeblink conditioning in mice lacking glutamate receptor δ2. J Biol Phys 28: 539-547, 2002


  28. Takatsuki K, Kawahara S, Kotani S, Fukunaga S, Mori H, Mishina M, Kirino Y: The hippocampus plays an important role in eyeblink conditioning with a short trace interval in glutamate receptor subunit δ2 mutant mice. J Neurosci 23, 17-22, 2003


  29. Townsend M, Yoshii A, Mishina M, Constantine-Paton M: Developmental loss of miniature N-methyl-D-aspartate receptor currents in NR2A knockout mice. Proc Natl Acad Sci USA 100: 1340-1345, 2003


  30. Fagiolini M, Katagiri H, Miyamoto H, Grant SGN, Mishina M, Hensch T: Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling. Proc Natl Acad Sci USA 100: 2854-2859, 2003


  31. Brickley SG, Misra C, Mok MHS, Mishina M, Cull-Candy SG: NR2B and NR2D subunits co-assemble in cerebellar Golgi cells to form a distinct NMDAR subtype restricted to extrasynaptic sites. J Neurosci 23: 4958-4966, 2003


  32. Okada H, Miyakawa N, Mori H, Mishina M, Miyamoto Y, Hisatsune T: NMDA receptors in cortical development are essential for the generation of coordinated increase in [Ca2+]i in eneuronal domainsf. Cereb Cortex 13: 749-757, 2003


  33. Inoue M Mishina, M, Ueda H: Locus-specific rescue of GluRe1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence. J Neurosci 23: 6529-6536, 2003


  34. Kitayama T, Mishina M, Sugiyama H: Enhancement of neurogenesis by running wheel exercises is suppressed in mice lacking NMDA receptor ε1 subunit. Neurosci Res 47: 55-63, 2003


  35. Mori H, Mishina M: Roles of diverse glutamate receptors in brain functions elucidated by subunit-specific and region-specific gene targeting. Life Sci 74, 329-336, 2003


  36. Takahashi Y, Mori H, Mishina M, Watanabe M, Fujiwara T, Shimomura J, Aiba H, Miyajima T, Saito Y, Nezu A, Nishida H, Imai K, Sakaguchi N, Kondo N: Autoantibodies to NMDA receptor in patients with chronic forms of epilepsia partialis continua. Neurology 61: 891-896, 2003


  37. Kitano T, Matsumura S, Seki T, Hikida T, Sakimura K, Nagano T, Mishina M, Nakanishi S, Ito S: Characterization of N-methyl-D-aspartate receptor subunits involved in acute ammonia toxicity. Neurochem Int 44: 83-90, 2004


  38. Miyamoto Y, Yamada K, Nagai T, Mori H, Mishina M, Furukawa H, Noda Y, Nabeshima T: Behavioral adaptations to addictive drugs in mice lacking the NMDA receptorε1 subunit. Eur J Neurosci 19, 151-158, 2004


  39. Murai N, Tsuji J, Ito J, Mishina M Hirano T: Vestibular compensation in glutamate receptor delta-2 subunit knockout mice: dynamic property of vestibulo-ocular reflex. Eur Arch Oto-Rhino-Laryngol 261: 82-86, 2004


  40. Yoshida T, Katoh A, Ohtsuki G, Mishina M, Hirano T: Oscillating Purkinje neuron activity causing involuntary movement in a mutant mouse deficient in the glutamate receptor δ2 subunit. J Neurosci 24: 2440-2448, 2004


  41. Uemura T, Mori H, Mishina M: Direct interaction of GluRδ2 with Shank scaffold proteins in cerebellar Purkinje cells. Mol Cell Neurosci 26: 330-341, 2004


  42. Fuse T, Kanai Y, Kanai-Azuma M, Suzuki M, Nakamura K, Mori H, Hayashi, Y, Mishina, M: Conditional activation of RhoA suppresses the epithelial to mesenchymal transition at the primitive streak during mouse gastrulation. Biochem Biophys Res Commun 318: 665-672, 2004


  43. Sato Y, Kobayashi E, Hakamata Y, Kobahashi M, Wainai T, Murayama T, Mishina M, Seo N: Chronopharmacological studies of ketamine in normal and NMDA ε1 receptor knockout mice. Br J Anaesth 92: 859-864, 2004


  44. Takehara K, Kawahara S, Munemoto Y, Kuriyama H, Mori H, Mishina M, Kirino Y: The NMDA receptor GluRε2 is important for delay and trace eyeblink conditioning in mice. Neurosci Lett 364: 43-47, 2004


  45. Abe M, Fukaya M, Yagi T, Mishina M, Watanabe M, Sakimura K: NMDA receptor GluRε/NR2 subunits are essential for postsynaptic localization and protein stability of GluRζ1/NR1 subunit. J Neurosci 24: 9292-9304, 2004


  46. Nishimura W, Muratani T, Tatsumi S, Sakimura K, Mishina M, Minami T, Ito S: Characterization of N-methyl-D-aspartate receptor subunits responsible for postoperative pain. Eur J Pharmacol 503: 71-75, 2004


  47. Ohtsuki G, Kawaguchi S, Mishina M, Hirano T: Enhanced inhibitory synaptic transmission in the cerebellar molecular layer of the GluRδ2 knockout mouse. J Neurosci 24: 10900-10907, 2004


  48. Takeuchi, T, Miyazaki T, Watanabe M, Mori H, Sakimura K, Mishina M: Control of synaptic connection by glutamate receptor δ2 in the adult cerebellum. J Neurosci 25: 2146-2156, 2005


  49. Sakamoto T, Takatsuki K, Kawahara S, Kirino Y, Niki H, Mishina M: Role of hippocampal NMDA receptors in trace eyeblink conditioning. Brain Res 1039: 130-136, 2005


  50. Hirai H, Miyazaki T, Kakegawa W, Matsuda S, Mishina M, Watanabe M, Yuzaki M: Rescue of abnormal phenotypes of the δ2 glutamate receptor-null mice by mutant δ2 transgenes. EMBO Rep 6: 90-95, 2005


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  1. Kawaguchi S, Hirano T: Suppression of inhibitory synaptic potentiation by presynaptic activity through postsynaptic GABAB receptors in a Purkinje neuron. Neuron 27: 339-347, 2000


  2. Imamura Y, Inokawa H, Ito A, Kadotani H, Toyama K, Noda S, Nakanishi S, Hirano T: Roles of GABAergic inhibition and NMDA receptor subunits in the spatio-temporal integration in the cerebellar cortex of mice. Neurosci Res 38: 289-301, 2000


  3. Okano H, Hirano T, Balaban E: Learning and memory. Proc Natl Acad Sci USA 97: 12403-12404, 2000


  4. Iwashita M, Kanai R, Funabiki K, Matsuda K, Hirano T: Dynamic properties, interactions and adaptive modifications of vestibulo-ocular reflex and optokinetic response in mice. Neurosci Res 39: 299-311, 2001


  5. Yamasaki T, Kawaji K, Ono K, Bito H, Hirano T, Osumi N, Kengaku M: Pax6 regulates granule cell polarization during parallel fiber formation in the developing cerebellum. Development 128: 3133-3144, 2001


  6. Kawaguchi S, Hirano T: Signaling cascade regulating long-term potentiation of GABAA receptor responsiveness in cerebellar Purkinje neurons. J Neurosci 22: 3969-3976, 2002


  7. Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M: Delta/Notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons. J Biol Chem 277: 25400-25407, 2002


  8. Fujii H, Hirano T: Calcineurin regulates induction of late phase of cerebellar long-term depression in rat cultured Purkinje neurons. Eur J Neurosci 16: 1777-1788, 2002


  9. Hirano, T, Watanabe D, Kawaguchi S, Pastan I, Nakanishi S: Roles of inhibitory interneurons in the cerebellar cortex. Ann N Y Acad Sci 978: 405-412, 2002


  10. Minami I, Kengaku M, Sillevis Smitt P, Shigemoto R, Hirano T: Long-term potentiation of mGluR1 activity by depolarization-induced Homer 1a in cerebellar Purkinje neurons. Eur J Neurosci 17: 1023-1032, 2003


  11. Coesmans M, Smitt PA, Linden DJ, Shigemoto R, Hirano T, Yamakawa Y, van Alphen AM, Luo C, van der Geest JN, Kros JM, Gaillard CA, Frens MA, de Zeeuw CI: Mechanism underlying cerebellar motor deficits due to mGluR1-autoantibodies. Ann Neurol 53: 325-336, 2003


  12. Kitano J, Nishida M, Itsukaichi Y, Minami I, Ogawa M, Hirano T, Mori Y, Nakanishi S: Direct interaction and functional coupling between metabotropic glutamate receptor subtype 1 and voltage-sensitive CaV2.1 Ca2+ channel. J Biol Chem 278: 25101-25108, 2003


  13. Murai N, Tsuji J, Ito J, Mishina M, Hirano T: Vestibular compensation in glutamate receptor δ-2 subunit knockout mice: dynamic property of vestibule-ocular reflex. Eur Arch Oto-Rhino-Laryngol 65: 82-86, 2004


  14. Kawaji, K, Umeshima H, Eiraku M, Hirano T, Kengaku M: Dual phases of migration of cerebellar granule cells guided by axonal and dendritic leading processes. Mol Cell Neurosci 25: 228-240, 2004


  15. Yoshida T, Katoh A, Ohtsuki G, Mishina M, Hirano T: Oscillating Purkinje neuron activity causing involuntary eye movement in a mutant mouse deficient in the glutamate receptor δ2 subunit. J Neurosci 24: 2440-2448 2004


  16. Shima Y, Kengaku M, Hirano T, Takeichi M, Uemura T: Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin. Dev Cell 7: 205-216, 2004


  17. Ohtsuki G, Kawaguchi S, Mishina M, Hirano T: Enhanced inhibitory synaptic transmission in the cerebellar molecular layer of the GluRδ2 knockout mouse. J Neurosci 24: 10900-10907, 2004


  18. Katoh A, Yoshida T, Himeshima Y, Mishina M, Hirano T: Defective control and adaptation of reflex eye movements in mutant mice deficient in either the glutamate receptor δ2 subunit or Purkinje cells. Eur J Neurosci 21: 1315-1326, 2005


  19. Eiraku M, Tohgo A, Ono K, Kaneko M, Fujishima K, Hirano T, Kengaku M: DNER acts as a neuron-specific Notch ligand during Bergmann glial development. Nat Neurosci 8: 873-880, 2005


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  1. Maejima T, Hashimoto K, Yoshida T, Aiba A, Kano M: Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron 31: 463-475, 2001


  2. Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K, Mishina M, Hashikawa T, Konnerth A, Watanabe M, Kano M: Roles of glutamate receptor δ2 subunit (GluR δ2) and metabotropic glutamate receptor subtype 1 (mGluR1) in climbing fiber synapse elimination during postnatal cerebellar development. J Neurosci 21: 9701-9712, 2001


  3. Shutoh F, Katoh A, Kitazawa H, Aiba A, Itohara S, Nagao S: Loss of adaptability of horizontal optokinetic response eye movements in mGluR1 knockout mice. Neurosci Res 42: 141-145, 2002


  4. Tabata T, Aiba A, Kano M: Extracellular calcium controls the dynamic range of neuronal metabotropic glutamate receptor responses. Mol Cell Neurosci 20: 56-68, 2002


  5. Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie S: Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet 11: 1731-1742, 2002


  6. Kishimoto Y, Fujimichi R, Araishi K, Kawahara S, Kano M, Aiba A, Kirino Y: mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning. Eur J Neurosci 16: 2416-2424, 2002


  7. Chida K, Hara T, Hirai T, Konishi C, Nakamura K, Nakao K, Aiba A, Katsuki M, Kuroki T: Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis. Cancer Res 63: 2404-2408, 2003


  8. Kuwajima M, Hall RA, Aiba A, Smith Y: Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the monkey subthalamic nucleus. J Comp Neurol 474: 589-602, 2004


  9. Nakamura M, Sato K, Fukaya M, Araishi K, Aiba A, Kano M, Watanabe M: Signaling complex formation of phospholipase Cβ4 with metabotropic glutamate receptor type 1α and 1,4,5-tris-phosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain. Eur J Neurosci 20: 2929-2944, 2004


  10. Tomemori Y, Ichiba M, Kusumoto A, Mizuno E, Sato D, Muroya S, Nakamura M, Kawaguchi H, Yoshida H, Ueno S, Nakao K, Nakamura K, Aiba A, Katsuki M, Sano A: A gene-targeted mouse model for chorea-acanthocytosis. J Neurochem 92: 759-766, 2005


  11. Maejima T, Oka S, Hashimotodani Y, Ohno-Shosaku T, Aiba A, Wu D, Waku K, Sugiura T, Kano M: Synaptically-driven endocannabinoid release requires Ca2+-assisted mGluR1-PLCβ4 signaling cascade in the cerebellum. J Neurosci 25: 6826-6835, 2005


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  1. Ohkura K, Suzuki N, Ishihara T, Katsura I: SDF-9, a protein tyrosine pshophatse-like molecule, regulates the L3/dauer developmental decision through hormonal signaling in C. elegans. Development 130: 3237-3248, 2003


  2. Miyahara K, Suzuki N, Ishihara T, Tsuchiya E, Katsura I: TBX2/TBX3 transcriptional factor homolog controls olfactory adaptation in Caenorhabditis elegans.J Neurobiol 58: 392-402, 2004


  3. Take-Uchi M, Kobayashi Y, Kimura KD, Ishihara T, Katsura I: FLR-4, a novel serine/threonine protein kinase, regulates defecation rhythm in Caenorhabditis elegans. Mol Biol Cell 16: 1355-1365, 2005


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  1. Kuruma A, Inoue T, Mikoshiba K: Dynamics of Ca2+ and Na+ in the dendrite of mouse cerebellar Purkinje cells evoked by parallel fiber stimulation. Eur J Neurosci 18: 2677-2689, 2003


  2. Fukami K, Yoshida M, Inoue T, Kurokawa M, Fissore RA, Yoshida N, Mikoshiba K, Takenawa T: Phospholipase Cδ4 is required for Ca2+-mobilization essential for acrosome reaction in sperm. J Cell Biol 161: 79-88, 2003


  3. Minoshima Y, Kawashima T, Hirose K, Tonozuka Y, Kawajiri A, Bao YC, Deng X, Tatsuka M, Narumiya S, Stratford May JrW, Nosaka T, Semba K, Inoue T, Satoh T, Inagaki M, Kitamura T: Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell 4: 549-560, 2003


  4. Nagase T, Ito KI, Kato K, Kaneko K, Kohda K, Matsumoto M, Hoshino A, Inoue T, Fujii S, Kato H, Mikoshiba K: Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP3 type 1 receptor.  Neuroscience 117: 821-830, 2003


  5. Yasuda H, Higashi H, Kudo Y, Inoue T, Hata Y, Mikoshiba K, Tsumoto T: Imaging of calcineurin activated by long-term depression-inducing synaptic inputs in living neurons of rat visual cortex. Eur J Neurosci 17: 287-297, 2003


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  1. Matsuo R, Murayama A, Saitoh Y, Sakaki Y, Inokuchi K: Identification and cataloging of genes induced by long-lasting long-term potentiation in awake rats. J Neurochem 74: 2239-2249, 2000


  2. Ikegami S, Inokuchi K: Antisense DNA against calcineurin facilitates memory in contextual fear conditioning by lowering the threshold for hippocampal long-term potentiation induction. Neuroscience 98: 637-646, 2000


  3. Saitoh Y, Inokuchi K: A triphasic curve characterizes the retention of lever-pressing behavior rewarded by lateral hypothalamic stimulation during the immediate-posttrial period in rats: implications for a transient intermediate stage between short and long-term memory. Neurosci Res 37: 211-219, 2000


  4. Tanaka T, Sugai M, Ito Y, Inokuchi K, Kohno T: Assignments of the 1H, 13C, and 15N resonances of the 21 kDa Vesl/Homer family protein, Vesl-1S. J Biomol NMR 18: 181-182, 2000


  5. Kato A, Fukuda T, Fukazawa Y, Isojima Y, Fujitani K, Inokuchi K, Sugiyama H: Phorbol esters promote postsynaptic accumulation of Vesl-1S/Homer-1a protein. Eur J Neurosci 13: 1292-1302, 2001


  6. Shinohara T, Tomizuka K, Miyabara S, Takehara S, Kazuki Y, Inoue J, Katoh M, Nakane H, Iino A, Ohguma A, Ikegami S, Inokuchi K, Ishida I, Reeves RH, Oshimura M: Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Downfs syndrome. Hum Mol Genet 10: 1163-1175, 2001


  7. Yamazaki M, Matsuo R, Fukazawa Y, Ozawa F, Inokuchi K: Regulated expression of an actin-associated protein, synaptopodin, during long-term potentiation. J Neurochem 79: 192-199, 2001


  8. Matsuo R, Asada A, Fujitani K, Inokuchi K: LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein. Biochem Biophys Res Commun 289: 479-484, 2001


  9. Ageta H, Kato A, Fukazawa Y, Inokuchi K, Sugiyama H: Effects of proteasome inhibitors on the synaptic localization of Vesl-1S/Homer-1a proteins. Mol Brain Res 97: 186-189, 2001


  10. Inoue Y, Honkura N, Kato A, Ogawa S, Udo H, Inokuchi K, Sugiyama H: Activity-inducible protein Homer1a/Vesl-1S promotes redistribution of postsynaptic protein Homer1c/Vesl-1L in cultured rat hippocampal neurons. Neurosci Lett 354: 143-147, 2004


  11. Inaba Y, Tian QB, Okano A, Zhang JP, Sakagami H, Miyazawa S, Li W, Komiyama A, Inokuchi K, Kondo H, Suzuki T: Brain-specific novel guanine nucleotide exchange factor for Arf, synArfGEF, is localized to postsynaptic density. J Neurochem 89: 1347-1357, 2004


  12. Sugiyama K, Niki T, Inokuchi K, Teranishi Y, Ueda M, Tanaka A: Hterologous expression of metabotropic glutamate receptor subtype 1 in Saccharomyces cerevisiae. Appl Microbiol Biotechnol 64: 531-536, 2004


  13. Inoue K, Fukazawa Y, Ogura A, Inokuchi K: Two-dimensional neural activity mapping of the entire population of hippocampal CA1 pyramidal cells responding to fear conditioning. Neurosci Res 51: 417-425, 2005


  14. Sakagami Y, Yamamoto K, Sugiura S, Inokuchi K, Hayashi T, Kato N: Roles of Homer-1a in homeostatic regulation of pyramidal cell excitability: a possible link to clinical benefits of electroconvalsive shock. Eur J Neurosci 21: 3229-3239, 2005


  15. Yamamoto K, Sakagami Y, Sugiura S, Inokuchi K, Shimohama S, Kato N: Homer-1a enhances spike-induced calciiuminflux via l-type calcium channels in neocortex pyramidal cells. Eur J Neurosci 22: 1338-1348, 2005


  16. Ehrengruber M, Kato A, Inokuchi K, Hennou S: Homer/Vesl proteins and their roles in CNS neurons. Mol Neurobiol 29: 213-228, 2004


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  1. Okuda T, Haga T: Functional characterization of the human high-affinity choline transporter. FEBS Lett 484: 92-97, 2000


  2. Misawa H, Nakata K, Matsuura J, Nagao M, Okuda T, Haga T: Distribution of the high-affinity choline transporter in the central nervous system of the rat. Neuroscience 105: 87-98, 2001


  3. Kobayashi Y, Okuda T, Fujioka Y, Matsumura G, Nishimura Y, Haga T: Distribution of the high-affinity choline transporter in the human and macaque monkey spinal cord. Neurosci Lett 317: 25-28, 2002


  4. Okuda T, Okamura M, Kaitsuka C, Haga T, Gurwitz D: Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate. J Biol Chem 277: 45315-45322, 2002


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  1. Tsubamoto Y, Eto K, Noda M, Daniel S, Suga S, Yamashita S, Kasai H, Wakui M, Sharp GW, Kimura S, Kadowaki T: Hexamminecobalt (III) chloride inhibits glucose-induced insulin secretion at the exocytotic process. J Biol Chem276: 2979-2985, 2001


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  1. Okere CO, Kaba H: Region-specific localization of glutamine synthetase immunoreactivity in the mouse olfactory bulb: implication for neuron-glia interaction in bulbar synaptic plasticity. Brain Res 857: 308-312, 2000


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  1. Tabata Y, Ouchi Y, Kamiya H, Manabe T, Arai K, Watanabe S: Specification of the retinal fate of mouse embryonic stem cells by ectopic expression of Rx/rax, a homeobox gene. Mol Cell Biol 24: 4513-4521, 2004


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  1. Tomita S, Fujita T, Kirino Y, Suzuki T: PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein. J Biol Chem 275: 13056-13060, 2000


  2. Inoue T, Watanabe S, Kawahara S, Kirino Y: Phase-dependent filtering of sensory information in the oscillatory olfactory center of a terrestrial mollusk. J Neurophysiol 84: 1112-1115, 2000


  3. Lee DS, Tomita S, Kirino Y, Suzuki T: Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein. J Biol Chem 275: 23134-23138, 2000


  4. Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, Greengard P, Kirino Y, Nairn AC, Suzuki T: Neuron-specific phosphorylation of Alzheimerfs beta-amyloid precursor protein by cyclin-dependent kinase 5. J Neurochem 75: 1085-1091, 2000


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  11. Shindo K, Shinozaki K, Kami K, Anzai K, Lee S, Aoyagi H, Kirino Y, Shimada I: Solution structure of micelle-bound H5 peptide (427-452): a primary structure corresponding to the pore forming region of the voltage dependent potassium channel. Biochim Biophys Acta 1545: 153-159, 2001


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  13. Inoue T, Watanabe S, Kirino Y: Serotonin and NO complementarily regulate generation of oscillatory activity in the olfactory CNS of a terrestrial mollusk. J Neurophysiol 85: 2634-2638, 2001


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‹v•Û@‹`O@iŽ©‘R‰ÈŠwŒ¤‹†‹@\E¶—ŠwŒ¤‹†Šj
  1. Kubo Y, Murata Y: Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel. J Physiol 531: 645-660, 2001


  2. Saitoh O, Masuho I, Terakawa I, Nomoto S, Asano T, Kubo Y: Regulator of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular localization and acute desensitization of G protein-gated K+ channels. J Biol Chem 276: 5052-5058, 2001


  3. Soom M, Schonherr R, Kubo Y, Kirsch C, Klinger R, Heinemann SH: Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels. FEBS lett 490: 49-53, 2001


  4. Murata Y, Okado H, Kubo Y: Characterization of heteromultimeric G-protein coupled inwardly rectifying potassium channels of the tunicate tadpole with a unique property. J Biol Chem 276: 18529-18539, 2001


  5. Murata Y, Okado H, Katsuyama Y, Okamura Y, Kubo Y: Primary structure, developmental expression and functional properties of an inward rectifier K+ channel of the tunicate. Receptors Channels 7: 387-399, 2001


  6. Misaka T, Miyashita T, Kubo Y: Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization and effect on mitochondrial morphology. J Biol Chem 277: 15834-15842, 2002


  7. Ai T, Fujiwara Y, Tsuji K, Otani H, Nakano S, Kubo Y, Horie M: Novel KCNJ2 mutation in familial periodic paralysis with ventricular dysrhythmia. Circulation 105: 2592-2594, 2002


  8. Saitoh O, Murata Y, Odagiri M, Itoh M, Itoh H, Misaka T, Kubo Y: Alternative splicing of RGS8 gene determines inhibitory function of receptor-type-specific Gq signaling. Proc Natl Acad Sci USA 99: 10138-10143, 2002


  9. Murata Y, Fujiwara Y, Kubo Y: Identification of a site involved in the block by extracellular Mg2+ and Ba2+ as well as permeation of K+ in Kir2.1 K+ channel. J Physiol 544: 665-677, 2002


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  1. Shirai Y, Segawa S, Kuriyama M, Goto K, Sakai N, Saito N: Subtype-specific translocation of diacylglycerol kinase alpha and gamma and its correlation with protein kinase C. J Biol Chem 275: 24760-24766, 2000


  2. Takeda M, Kagaya Y, Takahashi J, Sugie T, Ohta J, Watanabe J, Shirato K, Kondo H, Goto K: Gene expression and in situ localization of diacylglycerol kinase isozymes in normal and infarcted rat hearts: effects of captopril treatment. Circ Res 89: 265-272, 2001


  3. Caricasole A, Bettini E, Sala C, Roncarati R, Kobayashi N, Caldara F, Goto K, Terstappen GC: Molecular cloning and characterization of the human diacylglycerol kinase beta (DGKbeta) gene: alternative splicing generates DGKbeta isotypes with different properties. J Biol Chem 277: 4790-4796, 2002


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  1. Matsushita N, Okada H, Yasoshima Y, Takahashi K, Kiuchi K, Kobayashi K: Dynamics of tyrosine hydroxylase promoter activity during midbrain dopaminergic neuron development. J Neurochem 82: 295-304, 2002


  2. Baker H, Kobayashi K, Okano H, Saino-Saito S: Cortical and striatal expression of tyrosine hydroxylase mRNA in neonatal and adult mice. Cell Mol Neurobiol 23: 507-518, 2003


  3. Sano H, Yasoshima Y, Matsushita N, Kaneko T, Kohno K, Pastan I, Kobayashi K: Conditional ablation of striatal neuronal types containing dopamine D2 receptor disturbs coordination of basal ganglia function. J Neurosci23: 9078-9088, 2003


  4. Shin RM, Masuda M, Miura M, Sano H, Shirasawa T, Song WJ, Kobayashi K, Aosaki T: Dopamine D4 receptor-induced postsynaptic inhibition of GABAergic currents in mouse globus pallidus neurons. J Neurosci 23: 11662-11672, 2003


  5. Kobayashi K, Takahashi M, Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K: Survival of developing motor neurons by Rho GTPase signaling pathway through Rho-kinase. J Neurosci 24: 3480-3488, 2004


  6. Okada H, Matsushita N, Kobayashi K, Kobayashi K: Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons. J Neurochem 89: 7-14, 2004


  7. Yoshizaki T, Inaji M, Kouike H, Shimazaki T, Sawamoto K, Ando K, Date I, Kobayashi K, Suhara T, Uchiyama Y, Okano H: Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells. Neurosci Lett 363: 33-37, 2004


  8. Matsushita N, Kobayashi K, Miyazaki J, Kobayashi K: Fate of transient catecholaminergic cell types revealed by site-specific recombination in transgenic mice. J Neurosci Res 78: 7-15, 2004


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  10. Pignatelli A, Kobayashi K, Okano H, Belluzzi O: Functional properties of dopaminergic neurons in the mouse olfactory bulb. J Physiol 564: 501-514, 2005


  11. Matsusaka T, Xin J, Niwa S, Kobayashi K, Akatsuka A, Hashizume H, Wang QC, Pastan I, Fogo AB, Ichikawa I: Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocyte-specific injury. J Am Soc Nephrol 16: 1013-1023, 2005


  12. Jomphe C, Bourque MJ, Fortin GD, St-Gelais F, Okano H, Kobayashi K, Trudeau LE: Use of TH-GFP transgenic mice as a source of identified dopaminergic neurons for physiological studies in postnatal cell culture. J Neurosci Methods 146: 1-12, 2005


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  1. Matsuoka Y, Furuyashiki T, Bito H, Ushikubi F, Tanaka Y, Kobayashi T, Muro S, Satoh N, Kayahara T, Higashi M, Mizoguchi A, Shichi H, Fukuda Y, Nakao K, Narumiya S: Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes. Proc Natl Acad Sci USA 100: 4132-4137, 2003


âV“¡@®—º@i_ŒË‘åŠwEƒoƒCƒIƒVƒOƒiƒ‹Œ¤‹†ƒZƒ“ƒ^[j
  1. Sumioka K, Shirai Y, Sakai N, Hashimoto T, Tanaka C, Yamamoto M, Takahashi M, Ono Y, Saito N: Induction of 55 kDa PKN cleavage product by ischemia/reperfusion model in the rat retina. Invest Opthal Vis Sci 41: 29-35, 2000


  2. Sakai N, Kodama N, Ohmori S, Sasaki K, Saito N: Involvement of the actin cytoskeleton in the regulation of serotonin transporter (SET) activity: possible mechanism underlying SET regulation by protein kinase C. Neurochem Int 36: 567-579, 2000


  3. Oyasu M, Kuroda S, Nakashita M, Fujimiya M, Kikkawa U, Saito N: Immunocytochemical localization of a neuron-specific thrombospondin-1-like protein, NELL2: Light and electron microscopic studies in the rat brain. Mol Brain Res 76: 151-160, 2000


  4. Shirai Y, Kashiwagi K, Sakai N, Saito N: Phospholipase A2 and its products are involved in the purinergic receptor-mediated translocation of protein kinase C in CHO-K1 cells. J Cell Sci 113: 1335-1343, 2000


  5. Akiyama H, Kondoh T, Kokunai T, Nagashima T, Saito N, Tamaki N: Blood-brain barrier formation of grafted human umbilical vein endothelial cells in athymic mouse brain. Brain Res 858: 172-176, 2000


  6. Ueyama T, Ren Y, Ohmori S, Sakai K, Tamaki N, Saito N: cDNA cloning of an alternative splicing variant of protein kinase Cδ (PKC δIII), a new truncated form of PKCδ, in rats. Biochem Biophys Res Commun 269: 557-563, 2000


  7. Shirai Y, Segawa S, Kuriyama M, Goto K, Sakai N, Saito N: Subtype-specific translocation of diacylglycerol kinase alpha and gamma and its correlation with protein kinase C. J Biol Chem 275: 24760-24766, 2000


  8. Nakagawa N, Hoshijima M, Oyasu M, Saito N, Tanizawa K, Kuroda S: ENH, containing PDZ and LIM domain, heart/skeletal muscle-specific protein, associates with cytoskeletal protein through its PDZ domain. Biochem Biophys Res Commun 272: 505-512, 2000


  9. Shibaguchi H, Takemura K, Kan S, Kataoka Y, Kaibara M, Saito N, Taniyama K: Role of synaptophysin in exocytic release of dopamine from Xenopus oocytes injected with rat brain mRNA. Cell Mol Neurobiol 20: 401-408, 2000


  10. Ohmori S, Sakai N, Shirai Y, Yamamoto H, Miyamoto E, Shimizu N, Saito N: Importance of PKC targeting for the phosphorylation of its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS). J Biol Chem 275: 26449-26457, 2000


  11. Larsen EC, DiGennaro JA, Saito N, Mehta S, Loegering DJ, Mazurkiewicz JE, Lennartz MR: Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells. J Immunol 165: 2809-2817, 2000


  12. Yokogawa T, Nagata S, Nishio Y, Tsutsumi T, Ihara S, Shirai R, Morita K, Umeda M, Shirai Y, Saitoh N, Fukui Y: Evidence that 3'-phosphorylated polyphosphoinositides are generated at the nuclear surface: use of immunostaining technique with monoclonal antibodies specific for PI 3,4-P2. FEBS Lett 473: 222-226, 2000


  13. Tozaki H, Kanno T, Nomura T, Kondoh T, Kodama N, Saito N, Aihara H, Nagata T, Matsumoto S, Ohta K, Nagai K, Yajima Y, Nishizaki T: Role of glial glutamate transporters in the facilitatory action of FK960 on hippocampal neurotransmission. Mol Brain Res 97: 7-12, 2001


  14. Shindo M, Irie K, Ohigashi H, Kuriyama M, Saito N: Diacylglycerol kinase γ is one of the specific receptors of tumor-promoting phorbol esters. Biochem Biophys Res Commun 289: 451-456, 2001


  15. Kajimoto T, Ohmori S, Shirai Y, Sakai N, Saito N: Subtype-specific translocation of the δ subtype of protein kinase C and its activation by tyrosine phosphorylation induced by ceramide in HeLa cells. Mol Cell Biol 21: 1769-1783, 2001


  16. Nakai M, Tanimukai S, Yagi K, Saito N, Taniguchi T, Terashima A, Kawamata T, Yamamoto H, Fukunaga K, Miyamoto E, Tanaka C: Amyloid β protein activates PKC-δ and induces translocation of myristoylated alanine-rich C kinase substrate (MARCKS) in microglia. Neurochem Int 38: 593-600, 2001


  17. Mishima K, Otani H, Tanabe T, Kawasaki H, Oshiro A, Saito N, Ogawa R, Inagaki C: Molecular mechanisms for α2-adrenoceptor-mediated regulation of synoviocytes populations. Jpn J Pharmacol 85: 214-226, 2001


  18. Saito-Ito A, Yagi K, Saito N: Distinct distribution of four Ca2+-dependent subtypes of protein kinase C in rat olfactory bulb; definite expression of βII-subtype in the accessory olfactory bulb. Neurochem Int 39: 267-274, 2001


  19. Minami T, Hara K, Oshiro N, Ueoku S, Yoshino K, Tokunaga C, Shirai Y, Saito N, Gout I, Yonezawa K: Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha. Genes Cells 6: 1003-1015, 2001


  20. Ueyama T, Ren Y, Sakai N, Takahashi M, Ono Y, Kondoh T, Tamaki N, Saito N: Constitutively active fragment of PKN in microglia/macrophage after middle cerebral artery occlusion in rats. J Neurochem 79: 903-913, 2001


  21. Tada H, Uchino M, Nagai K, Nomura T, Kondoh T, Saito N, Yamamura T, Yajima Y, Nishizaki T: The anti-dementia drug FK960 stimulates glial glutamate release via a PKA pathway. Mol Brain Res 109: 63-8, 2002


  22. Kohjima M, Noda Y, Takeya R, Saito N, Takeuchi K, Sumimoto H: PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions. Biochem Biophys Res Commun 299: 641-646, 2002


  23. Larsen EC, Ueyama T, Brannock PM, Shirai Y, Saito N, Larsson C, Loegering D, Weber PB, Lennartz MR: Role for PKC-ε in FcγR-mediated phagocytosis by RAW 264.7 cells. J Cell Biol 159: 939-944, 2002


  24. Zhang X, Kuroda S, Carpenter D, Nishimura I, Soo C, Moats R, Iida K, Wisner E, Hu FY, Miao S, Beanes S, Dang C, Vastardis H, Longaker M, Tanizawa K, Kanayama N, Saito N, Ting K: Craniosynostosis in transgenic mice overexpressing Nell-1. J Clin Invest 110: 861-870, 2002


  25. Irie N, Sakai N, Ueyama T, Kajimoto T, Shirai Y, Saito N: Subtype- and species-specific knockdown of PKC using short interfering RNA (siRNA). Biochem Biophys Res Commun 298: 738-743, 2002


  26. Goerke A, Sakai N, Gutjahr E, Schlapkohl WA, Mushinski JF, Haller H, Kolch W, Saito N, Mischak H: Induction of apoptosis by protein kinase Cdelta is independent of its kinase activity. J Biol Chem 277: 32054-32062, 2002


  27. Ohta K, Nomura T, Kanno T, Nagai K, Yamamoto S, Yajima Y, Kondoh T, Kohmura E, Saito N, Nishizaki T: L-trans-PDC enhances hippocampal neuronal activity by stimulating glial glutamate release independently of blocking transporters. Biophys Biochem Res Commun 295: 376-381, 2002


  28. Tanimukai S, Hasegawa H, Nakai M, Yagi K, Hirai M, Saito N, Taniguchi T, Terashima A, Yasuda M, Kawamata T, Tanaka C: Nanomolar amyloid beta protein activates a specific PKC isoform mediating phosphorylation of MARCKS in Neuro2A cells. NeuroReport 13: 549-553, 2002


  29. Kashiwagi K, Shirai Y, Kuriyama M, Sakai N, Saito N: Importance of C1B domain for lipid messenger-induced targeting of PKC. J Biol Chem 277: 18037-18045, 2002


  30. Sakai K, Nakamura M, Ueno S, Sano A, Sakai N, Shirai Y, Saito N: The silencer activity of the novel human serotonin transporter linked polymorphic region. Neurosci Lett 327: 13-16, 2002


  31. Nishizaki T, Nagai K, Nomura T, Tada H, Kanno T, Tozaki H, Li XX, Kondoh T, Kodama N, Takahashi E, Sakai N, Tanaka K, Saito N: A new neuromodulatory pathway with a glial contribution mediated via A2a adenosine receptors. Glia 39: 133-147, 2002


  32. Sawano A, Saito N, Miyawaki A: Multiple-colour fluorescence imaging Ca2+-calmodulin, protein kinase C, and their conflicting convergence on a shared target using novel epi-fluorescent microscopy. Biophys J 82: 1076-1085, 2002


  33. Salli U, Saito N, Stormshak F: Spatio-temporal interactions of myristoylated alanine-rich C kinase substrate (MARCKS) protein with the actin cytoskeleton and exocytosis of oxytocin upon prostaglandin F2alpha stimulation of bovine luteal cells. Biol Reprod 69: 2053-2058, 2003


  34. Fredholm BB, Assender JW, Irenius E, Kodama N, Saito N: Synergistic effects of adenosine A1 and P2Y receptor stimulation on calcium mobilization and PKC translocation in DDT1 MF-2 cells. Cell Mol Neurobiol 23: 379-400, 2003


  35. Sasaki A, Taketomi T, Kato R, Saeki K, Nonami A, Sasaki M, Kuriyama M, Saito N, Shibuya M, Yoshimura A: Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1. Nat Cell Biol 5: 427-432, 2003


  36. Shindo M, Irie K, Masuda A, Ohigashi H, Shirai Y, Miyasaka K, Saito N: Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are new targets of tumor-promoting phorbol esters. J Biol Chem 278: 18448-18454, 2003


  37. Mogami H, Zhang H, Suzuki Y, Urano T, Saito N, Kojima I, Petersen OH: Decoding of short-lived Ca2+ influx signals into long term substrate phosphorylation through activation of two distinct classes of protein kinase C. J Biol Chem 278: 9896-9904, 2003


  38. Sakai K, Hasegawa C, Okura M, Morikawa O, Ueyama T, Shirai Y, Sakai N, Saito N: Novel variants of murine serotonin transporter mRNA and the promoter activity of its upstream sites. Neurosci Lett 342: 175-178, 2003


  39. Kuriyama M, Taniguchi T, Shirai Y, Sasaki A, Yoshimura A, Saito N: Activation and translocation of PKCdelta is necessary for VEGF-induced ERK activation through KDR in HEK293T cells. Biochem Biophys Res Commun 325: 843-851, 2004


  40. Bhattacharjee AK, Ueyama T, Kondoh T, Hayashi S, Abouelfetouh A, Sakai N, Saito N, Kohmura E: In vivo transgene expression using an adenoviral tetracycline-regulated system with neuron-specific enolase promoter. Biochem Biophys Res Commun 317: 1144-1148, 2004


  41. Ueyama T, Lennartz MR, Noda Y, Kobayashi T, Shirai Y, Rikitake K, Yamasaki T, Hayashi S, Sakai N, Seguchi H, Sawada M, Sumimoto H, Saito N: Superoxide production at phagosomal cup/phagosome through beta I protein kinase C during Fc gamma R-mediated phagocytosis in microglia. J Immunol 173: 4582-4589, 2004


  42. Sakai N, Tsubokawa H, Matsuzaki M, Kajimoto T, Takahashi E, Ren Y, Ohmori S, Shirai Y, Matsubayashi H, Chen J, Duman RS, Kasai H, Saito N: Propagation of γPKC translocation along the dendrites of Purkinje cell in γPKC-GFP transgenic mice. Genes Cells 9: 945-957, 2004


  43. Kageyama A, Oka M, Okada T, Nakamura S, Ueyama T, Saito N, Hearing VJ, Ichihashi M, Nishigori C: Down-regulation of melanogenesis by phospholipase D2 through ubiquitin proteasome-mediated degradation of tyrosinase. J Biol Chem 279: 27774-27780, 2004


  44. Yagi K, Shirai Y, Hirai M, Sakai N, Saito N: Phospholipase A2 products retain a neuron specific gamma isoform of PKC on the plasma membrane through the C1 domain--a molecular mechanism for sustained enzyme activity. Neurochem Int 45: 39-47, 2004


  45. Kajimoto T, Shirai Y, Sakai N, Yamamoto T, Matsuzaki H, Kikkawa U, Saito N: Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex. J Biol Chem 279: 12668-12676, 2004


  46. Uchino M, Sakai N, Kashiwagi K, Shirai Y, Shinohara Y, Hirose K, Iino M, Yamamura T, Saito N: Isoform-specific phosphorylation of mGluR5 by PKC blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC. J Biol Chem 279: 2254-2261, 2004


  47. Taniguchi T, Sumida M, Hiraoka S, Tomoo K, Kakehi T, Minoura K, Sugiyama S, Inaka K, Ishida T, Saito N, Tanaka C: Effects of different anti-tau antibodies on tau fibrillogenesis: RTA-1 and RTA-2 counteract tau aggregation. FEBS Lett 579: 1399-1404, 2005


  48. Fukunaga-Takenaka R, Shirai Y, Yagi K, Adachi N, Sakai N, Merino E, Merida I, Saito N: Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocophenol. Genes Cells 10: 311-319, 2005


  49. Seki T, Matsubayashi H, Amano T, Shirai Y, Saito N, Sakai N: Phosphorylation of PKC activation loop plays an important role in receptor-mediated translocation of PKC. Genes Cells 10: 225-239, 2005


  50. Matsuo A, Bellier JP, Hisano T, Aimi Y, Yasuhara O, Tooyama I, Saito N, Kimura H: Rat choline acetyltransferase of the peripheral type differs from that of the common type in intracellular translocation. Neurochem Int 46: 423-433, 2005


  51. Hayashi S, Ueyama T, Kajimoto T, Yagi K, Kohmura E, Saito N: Involvement of γPKC in estrogen-induced neuroprotection on focal brain ischemia through G protein-coupled estrogen receptor. J Neurochem 93: 883-891, 2005


  52. Adachi N, Oyasu M, Taniguchi T, Yamaguchi Y, Takenaka R, Shirai Y, Saito N: Immunocytochemical localization of a neuron-specific diacylglycerol kinase beta and gamma in the developing rat brain. Mol Brain Res 139: 288-299, 2005


  53. Ueyama T, Eto M, Kami K, Tatsuno T, Kobayashi T, Shirai Y, Lennartz MR, Takeya R, Sumimoto H, Saito N: Isoform-specific membrane targeting mechanism of Rac during Fc gammaR-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome. J Immunol 175: 2381-2390, 2005


  54. Abdel-Raheem IT, Hide I, Yanase Y, Shigemoto-Mogami Y, Sakai N, Shirai Y, Saito N, Hamada FM, El-Mahdy NA, Elsisy Ael-D, Sokar SS, Nakata Y: Protein kinase C-alpha mediates TNF release process in RBL-2H3 mast cells. Br J Pharmacol 145: 415-423, 2005


ꎓ¡@ŽÀ@i(à)“Œ‹ž“sˆãŠwŒ¤‹†‹@\E“Œ‹ž“s_Œo‰ÈŠw‘‡Œ¤‹†Šj
  1. Tamura T, Chiang AS, Ito N, Liu HP, Horiuchi J, Tully T, Saitoe M: Aging specifically impairs amnesiac-dependent memory in Drosophila. Neuron 40: 1003-1011, 2003


  2. Saitoe M, Tamura T, Horiuchi J, Ito N: Identification of the memory component that decays with age in Drosophila. Jpn J Neuropsychopharmacol 24: 231-237, 2004


  3. Xia S, Miyashita T, Fu T-G, Lin W-Y, Wu C-L, Pyzocha L, Lin I-R, Saitoe M, Tully T, Chiang A-S: NMDA receptors mediate olfactory learning and memory in Drosophila. Curr Biol 15: 603-615, 2005


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  1. Saito Y, Isa T: Local excitatory network and NMDA receptor activation generate a synchronous and bursting command from the superior colliculus. J Neurosci 23: 5854-5864, 2003


  2. Takazawa T, Saito Y, Tsuzuki K, Ozawa S: Membrane and firing properties of glutamatergic and GABAergic neurons in the rat medial vestibular nucleus. J Neurophysiol 92: 3106-3120, 2004


  3. Saito Y, Isa T: Laminar specific distribution of lateral excitatory connections in the rat superior colliculus. J Neurophysiol 92: 3500-3510, 2004


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  1. Sakai T, Tamura T, Kitamoto T, Kidokoro Y: A clock gene, period, plays a key role in long-term memory formation in Drosophila. Proc Natl Acad Sci USA101: 16058-16063, 2004


  2. Hou J, Kuromi H, Fukasawa Y, Ueno K, Sakai T, Kidokoro Y: Repetitive exposures to nicotine induce a hyper-responsiveness via the cAMP/PKA/CREB signal pathway in Drosophila. J Neurobiol 60: 249-261, 2004


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  1. Tanaka J, Nakagawa S, Kushiya E, Yamasaki M, Fukaya M, Iwanaga T, Simon MI, Sakimura K, Kano M, Watanabe M: Gq protein alpha subunits Galphaq and Galpha11 are localized at postsynaptic extra-junctional membrane of cerebellar Purkinje cells and hippocampal pyramidal cells. Eur J Neurosci 12: 781-792, 2000


  2. Minami T, Okuda-Ashitaka E, Mori H, Sakimura K, Watanabe M, Mishina M, Ito S: Characterization of nociceptin/orphanin FQ-induced pain responses in conscious mice: neonatal capsaicin treatment and N-methyl-D-aspartate receptor GluRε subunit knockout mice. Neuroscience 97: 133-142, 2000


  3. Yamakura T, Sakimura K, Shimoji K: N-methyl-D-aspartate receptor channel block by meperidine is dependent on extracellular pH. Anesth Analg 90: 928-932, 2000


  4. Yamakura T, Sakimura K, Shimoji K: The stereoselective effects of ketamine isomers on heteromeric N-methyl-D-aspartate receptor channels. Anesth Analg 91: 225-229, 2000


  5. Ito I, Kawakami R, Sakimura K, Mishina M, Sugiyama H: Input-specific targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal neuron synapses. Neuropharmacology 39: 943-951, 2000


  6. Kitayama K, Abe M, Kakizaki T, Honma D, Natsume R, Fukaya M, Watanabe M, Miyazaki J, Mishina M, Sakimura K: Purkinje cell-specific and inducible gene recombination system generated from C57BL/6 mouse ES cells. Biochem Biophys Res Commun 281: 1134-1140, 2001


  7. Minami T, Matsumura S, Okuda-Ashitaka E, Shimamoto K, Sakimura K, Mishina M, Mori H, Ito S: Characterization of the glutamatergic system for induction and maintenance of allodynia. Brain Res 895: 178-185, 2001


  8. Yamazaki M, Fukaya M, Abe M, Ikeno K, Kakizaki T, Watanabe M, Sakimura K: Differential palmitoylation of two mouse glutamate receptor interacting protein 1 forms with different N-terminal sequences. Neurosci Lett 304: 81-84, 2001


  9. Yamada K, Fukaya M, Shimizu H, Sakimura K, Watanabe M: NMDA receptor subunits GluR ε1, GluR ε3 and GluR ζ1 are enriched at the mossy fibre-granule cell synapse in the adult mouse cerebellum. Eur J Neurosci 13: 2025-2036, 2001


  10. Takeuchi T, Kiyama Y, Nakamura K, Tsujita M, Matsuda I, Mori H, Munemoto Y, Kuriyama H, Natsume R, Sakimura K, Mishina M: Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex. Eur J Neurosci 14: 153-160, 2001


  11. Ikeno K, Yamakura T, Yamazaki M, Sakimura K: The Lurcher mutation reveals Ca2+ permeability and PKC modification of the GluRδ channels. Neurosci Res 41: 193-200, 2001


  12. Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K, Mishina M, Hashikawa T, Konnerth A, Watanabe M, Kano M: Roles of glutamate receptor delta 2 subunit (GluRdelta 2) and metabotropic glutamate receptor subtype 1 (mGluR1) in climbing fiber synapse elimination during postnatal cerebellar development. J Neurosci 21: 9701-9712, 2001


  13. Ichikawa R, Miyazaki T, Kano M, Hashikawa T, Tatsumi H, Sakimura K, Mishina M, Inoue Y, Watanabe M: Distal extension of climbing fiber territory and multiple innervation caused by aberrant wiring to adjacent spiny branchlets in cerebellar Purkinje cells lacking glutamate receptor delta 2. J Neurosci 22: 8487-8503, 2002


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  1. Satake S, Saitow F, Rusakov D, Konishi S: AMPA receptor-mediated presynaptic inhibition at cerebellar GABAergic synapses: a characterization of molecular mechanisms. Eur J Neurosci 19: 2464-2474, 2004


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  1. Qiu Q, Sora I, Ren K, Uhl GR, Dubner R: Enhanced delta-opioid receptor-mediated antinociception in mu-opioid receptor-deficient mice. Eur J Pharmacol 387: 163-169, 2000


  2. Hosohata Y, Vanderah TW, Burkey TH, Ossipov MH, Kovelowski CJ, Bian D, Sora I, Uhl GR, Zhang X, Rice KC, Roeske WR, Hruby VJ, Yamamura HI, Porreca F: Delta opioid receptor agonists produce antinociception and [35S]GTP gammaS binding in mu-opioid receptor knock-out mice. Eur J Pharmacol 388: 241-248, 2000


  3. LaBuda CJ, Sora I, Uhl GR, Fuchs PN: Stress-induced analgesia in mu-opioid receptor knockout mice reveals normal function of the delta-opioid receptor system. Brain Res 869: 1-5, 2000


  4. Uhl GR, Li S, Takahashi N, Itokawa K, Lin Z, Hazama M, Sora I: The VMAT2 gene in mice and humans:amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins. FASEB J 14: 2459-2465, 2000


  5. Wisor JP, Nishino S, Sora I, Uhl GR, Mignot E, Edgar DM: Dopaminergic role in stimulant-induced wakefulness. J Neurosci 21: 1787-1794, 2001


  6. Hall FS, Sora I, Uhl GR: Ethanol consumption and reward are decreased in mu-opiate receptor knockout mice. Psychopharmacology 154: 43-49, 2001


  7. Sora I, Elmer G, Funada M, Pieper J, Li XF, Hall FS, Uhl GR: Mu opiate receptor gene dose effects on different morphine actions. evidence for differential in vivo mu receptor reserve. Neuropsychopharmacology 25: 41-54, 2001


  8. Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR: Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci USA 98: 5300-5305, 2001


  9. Yamamoto H, Karasawa J, Sagi N, Takahashi S, Horikomi K, Okuyama S, Nukada T, Sora I, Yamamoto T: Multiple pathways of sigma1 receptor ligand uptakes into primary cultured neuronal cells. Eur J Pharmacol 425: 1-9, 2001


  10. Yuyama K, Yamamoto H, Nakamura K, Kato T, Sora I, Yamamoto T: Resistance of PC12 cells against nitric oxide (NO)-induced toxicity in long-term cultureFimplication of neuronal NO synthase expression. Neurosci Lett 309: 169-172, 2001


  11. Persico AM, Mengual E, Moessner R, Hall FS, Revay RS, Sora I, Arellano J, DeFelipe J, Giménez-Amaya JM, Conciatori M, Marino R, Baldi A, Cabib S, Pascucci T, Uhl GR, Murphy DL, Lesch KP, Keller F: Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. J Neurosci 21: 6862-6873, 2001


  12. Zhou Y, Spangler R, Schlussman SD, Yuferov VP, Sora I, Ho A, Uhl GR, Kreek MJ: Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotrophin- releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice. Synapse 45: 220-229, 2002


  13. Mizoguchi H, Wu HE, Narita M, Hall FS, Sora I, Uhl GR, Nagase H, Tseng LF: Antagonistic property of buprenorphine for putative epsilon-opioid receptor-mediated G-protein activation by beta-endorphin in pons/medulla of the mu-opioid receptor knockout mouse. Neuroscience 115: 715-721, 2002


  14. Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, Murphy DL, Uhl GR: Cocaine mechanisms enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience 115: 153-161, 2002


  15. Karasawa J, Yamamoto H, Yamamoto T, Sagi N, Horikomi K, Sora I: MS-377, a selective sigma receptor ligand, indirectly blocks the action of PCP in the N-methyl-D-aspartate receptor ion-channel complex in primary cultured rat neuronal cells. Life Sci 70: 1631-1642, 2002


  16. Ikeda K, Kobayashi T, Kumanishi T, Yano R, Sora I, Niki H: Molecular mechanisms of analgesia induced by opioids and ethanol: is the GIRK channel one of the keys? Neurosci Res 44: 121-131, 2002


  17. Uhl GR, Hall FS, Sora I: Cocaine, reward, movement and monoamine transporters. Mol Psychiatry 7: 21-26, 2002


  18. Mizoguchi H, Tseng LF, Suzuki T, Sora I, Narita M: Differential mechanism of G-protein activation induced by endogenous mu-opioid peptides, endomorphin and beta-endorphin. Jpn J Pharmacol 89: 229-234, 2002


  19. Hall FS, Sora I, Uhl GR: Sex-dependent modulation of ethanol consumption in vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) knockout mice. Neuropsychopharmacology 28: 620-628, 2003


  20. Hall FS, Li XF, Goeb M, Roff R, Hoggatt H, Sora I, Uhl GR: Congenic C57BL/6 mu opiate receptor (MOR) knockout mice: baseline and opiate effects. Genes Brain Behav 2: 114-121, 2003


  21. Yuyama K, Yamamoto H, Nakamura K, Nrshizaki I, Yamakuni T, Si-Young Song, Sora I, Nagatsu T, Yamamoto T: Overexpression of V-1 prevents NO-induced cell death: involvement of enhanced tetrahydrobiopterin (BH4) biosynthesis. J Neurosci Res 72: 716-725, 2003


  22. Yuyama K, Yamamoto H, Nishizaki I, Kato T, Sora I, Yamamoto T: Caspase-independent cell death by low concentrations of nitric oxide (NO) in PC12 cellsFinvolvement of the inhibition of cytochrome C oxidase and the production of reactive oxygen species (ROS) in mitochondria. J Neurosci Res 73: 351-363, 2003


  23. Itokawa M, Arai M, Kato S, Ogata Y, Furukawa A, Haga S, Ujike H, Sora I, Ikeda K, Yoshikawa T: Association between a novel polumorphism in the promoter region of the neuropeptide Y gene and schizophrenia in humans. Neurosci Lett 347: 202-204, 2003


  24. Ujike H, Harano M, Inada T, Yamada M, Komiyama T, Sekine Y, Sora I, Iyo M, Katsu T, Nomura A, Nakata K, Ozaki N: Nine-or fewer repeat alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk factor for prolonged methamphetamine psychosis. Pharmacogenomics J 3: 242-247, 2003


  25. Mizoguchi H, Wu HE, Narita M, Sora I, Hall FS, Uhl GR, Loh HH, Nigase H, Tseng F: Lack of the mu-opioid receptor-mediated G-protein activation in the mouse spinal cord lacking exon1 and exon 2 & 3 of MOR-1 gene. J Pharmacol Sci 93: 423-429, 2003


  26. Murphy DL, Uhl GR, Holmes A, Ren-Patterson R, Hall FS, Sora I, Detera-Wadleigh S, Lesch KP: Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes Brain Behav 2: 350-364, 2003


  27. HallFS, GoebM, Li XF, SoraI, Uhl GR: Mu opioid receptor knockout mice display reduced cocaine conditioned place preference but enhanced sensitization of cocaine-induced locomotion. Mol Brain Res 121: 123-130, 2004


  28. Koizumi H, Hashimoto K, Kumakiri C, Shimizu E, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Takei N, Iyo M: Association between the glutathione S-transferase M1 gene deletion and female methamphetamine abusers. Am J Med Genet 126B: 43-45, 2004


  29. Yamamoto T, Nishizaki I, Nukada T, Kamegaya F, Furuya S, Hirabayashi Y, Ikeda K, Hata H, Kobayashi H, Sora I, Yamamoto H: Functional identification of ASCT1 neutral amino acid transporter as the predominant system for the uptake of L-serine in rat neurons in primaryculture.Neurosci Res 49: 101-111, 2004


  30. Mansikka H, Zhao C, Sheth RN, Sora I, Uhl GR, Raja SN: Nerve injury induces a tonic bilateral mu-opioid receptor-mediated inhibitory effect on mechanical allodynia in mice. Anesthesiology 100: 912-921, 2004


  31. Arai M, Itokawa M, Yamada K, Toyota T, Arai M, Haga S, Ujike H, Sora I, Ikeda K, Yoshikawa T: Association of neural cell adhesion molecule 1gene polymorphisms with bipolar affective disorder in Japanese individuals. Biol Psychiatry 55: 804-810, 2004


  32. Kockelkorn TT, Arai M, Matsumoto H, Fukuda N, Yamada K, Minabe Y, Toyota T, Ujike H, Sora I, Mori N, Yoshikawa T, Itokawa M: Association study of polymorphisms in the 5' upstream region of human DISC1 gene with schizophrenia. Neurosci Lett 368: 41-45, 2004


  33. Shen H, Hagino Y, Kobayashi H, Shinohara-Tanaka K, Ikeda K, Yamamoto H, Yamamoto T, Lesch KP, Murphy DL, Hall FS, Uhl GR, Sora I: Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology 29: 1790-1799, 2004


  34. Ide S, Minami M, Satoh M, Uhl GR, Sora I, Ikeda K: Buprenorphine antinociception is abolished, but naloxone-sensitive reward is retained, in mu-opioid receptor knockout mice. Neuropsychopharmacology 29: 1656-1663, 2004


  35. Yamamoto H, Imai K, Takamatsu Y, Kamegaya E, Hara Y, Shimada K, Yamamoto T, Shen HW, Hagino Y, Kobayashi H, Ide S, Sora I, Koga H, Ikeda K: Changes in expression of the mouse homologues of KIAA genes after subchronic methamphetamine treatment. Ann NY Acad Sci 1025: 92-101, 2004


  36. Han W, Ide S,Sora I, Yamamoto H, Ikeda K: A possible genetic mechanism underlying individual and interstrain differences in opioid actions: focus on the mu opioid receptor gene. Ann NY Acad Sci 1025: 370-375, 2004


  37. Ide S, Kobayashi H, Tanaka K, Ujike H, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama T, Yamada M, Iyo M, Ikeda K, Sora I: Gene polymorphisms of the mu opioid receptor in methamphetamineabusers. Ann NY Acad Sci 1025: 316-324, 2004


  38. Hironaka N, Ikeda K, Sora I, Uhl GR, Niki H: Food-reinforced operant behavior in dopamine transporter knockout mice: enhanced resistance to extinction. Ann NY Acad Sci 1025: 140-145, 2004


  39. Kobayashi H, Ide S, Hasegawa J, Ujike H, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama T, Yamada M, Iyo M, Shen HW, Ikeda K, Sora I: Study of association between alfa-synuclein gene polymorphism and methamphetamine psychosis/ dependence. Ann NY Acad Sci 1025: 325-334, 2004


  40. Harano M, Uchimura N, Abe H, Ishibashi M, Iida N, YanagimotoK, Tanaka T, Maeda H, SoraI, Iyo M, Komiyama T, Yamada M, Sekine Y, Inada T, Ozaki N, Ujike H: A polymorphism of DRD2 gene and brain atrophy in methamphetamine psychosis. Ann NY Acad Sci 1025: 307-315, 2004


  41. InadaT, IijimaY, UchidaN, MaedaT, IwashitaS, OzakiN, HaranoM, KomiyamaT, YamadaM, SekineY, IyoM, SoraI, Ujike H: No association between the type 1 sigma receptor gene polymorphisms and methamphetamine abuse in the Japanese population: A collaborative study by the Japanese Genetics Initiative for Drug Abuse (JGIDA). Ann NY Acad Sci 1025: 27-33, 2004


  42. IwataN, InadaT, HaranoM, KomiyamaT, YamadaM, SekineY, IyoM, SoraI, UjikeH, OzakiN: No association between the candidate genes of t-PA/Plasminogen system and Japanese methamphetamine related disorder: A collaborative study by the Japanese Genetics Initiative for Drug Abuse (JGIDA). Ann NY Acad Sci 1025: 34-38, 2004


  43. Numachi Y, Yoshida S, Yamashita M, Fujiyama K, Naka M, Matsuoka H, Sato M, Sora I: Psychostimulant alters expression of DNA methyltransferase mRNA in the rat brain. Ann NY Acad Sci 1025: 102-109, 2004


  44. Hall FS, Sora I, Drgonova J, Li XF, Goeb M, Uhl GR: Molecular mechanisms underlying the rewarding effects of cocaine. Ann NY Acad Sci 1025: 47-56, 2004


  45. Morita Y, Ujike H, Tanaka Y, Uchida N, Nomura A, Ohtani K, Kishimoto M, Morio A, Imamura T, Sakai A, Inada T, Harano M, Komiyama T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S: A nonsynonymous polymorphism in the human fatty acid amide hydrolase gene did not associate with either methamphetamine dependence or schizophrenia. Neurosci Lett 376: 182-187, 2005


  46. Nishiyama T, Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Sekine Y, Iyo M, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Inada T, Furukawa T, Ozaki N: Haplotype association between GABA(A) receptor gamma2 subunit gene (GABRG2) and methamphetamine use disorder. Pharmacogenomics J 5:89-95, 2005


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