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平成15年度
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A01班 |
桝 正幸(筑波大学・基礎医学系) 2.Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi
H, Kageyama R, Matsui A: Conversion of biliary system to pancreatic
tissue
in Hes1-deficient mice. Nat Genet 36: 83-87, 2004 2.Kayahara T, Sawada M, Takaishi S, Fukui H, Seno H, Fukuzawa H, Suzuki K, Hiai H, Kageyama R, Okano H, Chiba T: Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine. FEBS Lett 535: 131-135, 2003 3.Sasaki T, Kitagawa K, Sugimura S, Omura-Matsuoka E, Tanaka S, Yagita Y, Okano H, Matsumoto M, Hori M: Implication of cyclooxygenase-2 on enhanced proliferation of neural progenitor cells in the adult mouse hippocampus after ischemia. J Neurosci Res 72: 461-471, 2003 4.Nakamura Y, Yamamoto M, Oda E, Yamamoto A, Kanemura Y, Hara M, Suzuki A, Yamasaki M, Okano H: Expression of tubulin ßII in neural stem/progenitor cells and radial fibers during human fetal brain development. Lab Invest 83: 479-489, 2003 5.Yuasa Y, Okabe M, Yoshikawa S, Tabuchi K, Xiong W-C, Hiromi Y, Okano H: Drosophila homeodomain protein REPO controls glial differentiation by cooperating with ETS and BTB transcription factors. Development 130: 2419-2428, 2003 6.Uchida K, Okano H, Hayashi T, Mine Y, Tanioka Y, Nomura T, Kawase T: Grafted swine neuroepithelial stem cells can form myelinated axons and both efferent and afferent synapses with xenogeneic rat neurons. J Neurosci Res 72: 661-669, 2003 7.Kokuzawa J, Yoshimura S, Kitajima H, Shinoda J, Kaku Y, Iwama T, Morishita R, Shimazaki T, Okano H, Kunisada T, Sakai N: Hepatocyte growth factor promotes proliferation and neural differentiation of neural stem cells from mouse embryos. Mol Cell Neurosci 24: 190-197, 2003 8.Ishizuya-Oka A, Shimizu K, Sakakibara SI, Okano H, Ueda S: Thyroid hormone-upregulated expression of Musashi-1 is specific for progenitor cells of the adult epithelium during amphibian gastrointestinal remodeling. J Cell Sci 116: 3157-3164, 2003 9.Kanuka H, Kuranaga E, Hiratou T, Igaki T, Nelson B, Okano H, Miura M: Cytosol-endoplasmic reticulum interplay by Sec61α translocon in polyglutamine-mediated neurotoxicity in Drosophila . Proc Natl Acad Sci USA 100: 11723-11728, 2003 10.Baker H, Kobayashi K, Okano H, Saino-Saito S: Cortical and striatal expression of tyrosine hydroxylase mRNA in neonatal and adult mice. Cell Mol Neurobiol 23: 503-518, 2003 11.Tamaki T, Akatsuka A, Okada Y, Matsuzaki Y, Okano H, Kimura M: Growth and differentiation potential of main- and side-population cells derived from murine skeletal muscle. Exp Cell Res 291: 83-90, 2003 12.Miyanomori Y, Kobayashi H, Watanabe M, Nagata T, Imai T, Uesugi S, Okano H, Katahira M: Origin of figher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics. J Biol Chem 278: 41309-41315, 2003 13.Yoshida T, Tokunaga A, Nakao K, Okano H: Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas. Differentiation 71: 486-495, 2003 14.Hu QD, Ang BT, Karsak M, Hu WP, Cui XY, Duka T, Takeda Y, Chia W, Natesan S, Ng YK, Ling EA, Israel A, Maciag T, Small D, Trifonova R, Kopan R, Okano H, Nakafuku M, Chiba S, Hirai H, Schachner M, Pallen CJ, Watanabe K, Xiao ZC: F3/Contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell 115: 163-175, 2003 15.Matsuzaki Y, Kinjo K, Mulligan RC, Okano H: Unexpectedly efficient homing capacity of purified murine hematopoietic stem cell. Immunity 20: 87-93, 2004 16.Murata J, Murayama A, Horii A, Doi K, Harada T, Okano H, Kubo T: Expression of Musashi1, a neural RNA-binding protein, in the cochler of young adult mice. Neurosci Lett 354: 201-204, 2004 17.Okada S, Nakamura M, Mikami Y, Shimzakai T, Ohsugi Y, Yoshizaki K, Kishimoto T, Toyama Y, Okano H: Blockade of interleukin-6 receptor ameliorates functional recovery in spinal cord injury. J Neurosci Res in press 18.Yamashima T, Tonchev BA, Seki T, Sawamoto K, Okano H: Vascular adventitia generates neuronal progenitors in monkey hippocampus after ischemia. Hippocampus in press 19.Ieda M, Fukuda K, Kimura K, Hisaka Y, Kawaguchi H, Shimoda K, Takeshita E, Okano H, Kurihara Y, Kurihara H, Ishida J, Fukamizu A, Salamone L, Howard J.F, Ogawa S: Endothelin-1 regulates cardiac sympathetic nerve innervation in the rodent heart by controlling nerve growth factor expression. J Clin Invest in press 20.Watanabe K, Nakamura M, Iwanami A, Fujita Y, Kanemura Y, Toyama Y, Okano H: Comparison between fetal spinal cord-and forebrain-derived neural stem/progenitor cells as a source of transplantation for spinal cord injury. Dev Neurosci in press 21.Ohba H, Chiyoda T, Endo E, Yano M, Hayakawa Y, Sakaguchi M, Darnell RB, Okano HJ, Okano H: Sox21 is a repressor of neuronal differentiation and is antagonized by YB-1. Neurosci Lett in press 22.Mikami Y, Okano H, Sakaguchi M, Nakamura M, Shimazaki T, Okano HJ, Kawakami Y, Toyama Y, Toda M: Implantation of dendritic cells in the injured adult spinal cord results in activation of the endogenous neural/progenitor cells for de novo neurogenesis and axonal regeneration, leading to functional recovery. J Neurosci Res in press 23.Ozawa Y, Nakao K, Takeda J, Akira Gruss P, Hirano T, Oguchi Y, Okano H: Down-regulation of STAT3 activation is required as an intrinsic factor to complete rod photoreceptor differentiation. Mol Cell Neurosci in press 24.Sakaguchi H, Yaoi T, Suzuki T, Okano H, Hisa Y, Fushiki N: Spatiotemporal patterns of Musashi1 expression during inner ear development. NeuroReport in press 25.Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K,
Okano H: Mapping spatio-temporal activation of Notch signaling during
neurogenesis and gliogenesis in the developing mouse brain. J Neurochem in press 2.Aruga J, Yokota N, Mikoshiba K: Human SLITRK family genes, genomic organization and expression profiling in normal brain and brain tumor tissue. Gene 315: 87-94, 2003 3.Aruga J: Slitrk6 expression profile in the mouse embryo and its relationship to that of Nlrr3. Gene Expr Patterns 3: 727-733, 2003 4.Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA: Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell 114: 545-557, 2003 5.Hoshino J, Aruga J, Ishiguro A, Mikoshiba K: Dorz1, a novel gene expressed in differentiating cerebellar granule neurons, is down-regulated in Zic1-deficient mouse. Mol Brain Res 120: 57-64, 2003 6.Inoue T, Hatayama M, Tohmonda T, Itohara S, Aruga J, Mikoshiba
K: Mouse Zic5 deficiency results in neural tube defects and hypoplasia
of cephalic neural crest derivatives. Dev Biol in press 2.Takahashi I, Akaishi E, Abe Y, Ishikawa R, Tanaka S, Hosaka K, Kubohara Y: Zinc inhibits calcineurin activity in vitro by competing with nickel. Biochem Biophys Res Commun 307: 64-68, 2003 3.Shimizu K, Murata T, Tagawa T, Takahashi K, Ishikawa R,
Abe Y, Hosaka K, Kubohara Y: Calmodulin-dependent cyclic nucleotide
phosphodiesterase (PDE1) is a pharmacological target of DIF-1, an anti-tumor
agent isolated from Dictyostelium. Cancer Res in press 2.Kamimura M, Matsumoto K, Koshiba-Takeuchi K, Ogura T: Vertebrate Crossveinless 2 is secreted and acts as a modulator of the BMP signaling cascade. Dev Dyn in press 3.Matsumoto K, Nishihara S, Kamimura M, Otoguro T, Uehara
M, Maeda Y, Ogura K, Lumsden A, Ogura T: The Iroquois prepattern gene
Irx2 induces the complete transformation of tectum to cerebellum. Nat
Neurosci in press 2.Amano M, Kaneko T, Maeda A, Nakayama M, Ito M, Yamauchi T, Goto H, Fukata Y, Oshiro N, Shinohara A, Iwamatsu A, Kaibuchi K: Identification of tau and MAP2 as novel substrates of Rho-kinase and myosin phosphatase. J Neurochem 87: 780-790, 2003 3.Becknell B, Shen T, Maghraby E, Taya S, Kaibuchi K, Caligiuri MA, Marcucci G: Characterization of leukemia-associated Rho guanine nucleotide exchange factor (LARG) expression during murine development. Cell Tissue Res 314: 361-366, 2003 4.Shimizu T, Ihara K, Maesaki R, Amano M, Kaibuchi K, Hakoshima T: Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase. J Biol Chem 278: 46046-46051, 2003 5.Suzuki Y, Nakagomi S, Namikawa K, Kiryu-Seo S, Inagaki N, Kaibuchi K, Aizawa H, Kikuchi K, Kiyama H: Collapsin response mediator protein-2 accelerates axon regeneration of nerve-injured motor neurons of rat. J Neurochem 86: 1042-1050, 2003 6.Tharaux PL, Bukoski RC, Rocha PN, Crowley SD, Ruiz P, Nataraj C, Howell DN, Kaibuchi K, Spurney RF, Coffman TM: Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells. J Immunol 171: 96-105, 2003 7.Ito K, Hirooka Y, Sakai K, Kishi T, Kaibuchi K, Shimokawa H, Takeshita A: Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension. Circ Res 92: 1337-1343, 2003 8.Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, Just I: Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex. J Biol Chem 278: 28523-28527, 2003 9.Su L, Hattori M, Moriyama M, Murata N, Harazaki M, Kaibuchi K, Minato N: AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1. J Biol Chem 278: 15232-152328, 2003 10.Birukova AA, Smurova K, Birukov KG, Kaibuchi K, Garcia JG, Verin AD: Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction. Microvasc Res 67: 64-77, 2004 11.Noritake J, Fukata M, Sato K, Nakagawa M, Watanabe T, Izumi N, Wang S, Fukata Y, Kaibuchi K: Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact. Mol Biol Cell 15: 1065-1076, 2004 12.Ito K, Hirooka Y, Kishi T, Kimura Y, Kaibuchi K, Shimokawa H, Takeshita A: Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition. Hypertension 43: 156-162, 2004 13.Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K: Role of the PAR-3/KIF3 complex in the establishment of neuronal polarity. Nat Cell Biol in press 14.Menager C, Arimura N, Fukata Y, Kaibuchi K: PIP3 is involved
in neuonal polarization and axon formation. J Neurochem in press 2.Chang C, Tsai C, Wang H, Tsai H, Chen H, Tsai T, Takahashi H, Li H, Fann M, Yang C, Hayashizaki Y, Saito T, Liu F: Identification of a developmentally regulated striatum-enriched zinc-finger gene, Nolz-1, in the mammalian brain. Proc Natl Acad Sci USA 101: 2613-2618, 2004 3.Miyagi S, Saito T, Mizutani K, Masuyama N, Gotoh Y, Iwama
A, Nakauchi H, Masui S, Niwa H, Nishimoto M, Muramatsu M, Okuda A:
The Sox-2 regulatory regions display their activities in two distinct
multipotent stem cells. Mol Cell Biol in press 2.Shintani T, Kato A, Yuasa-Kawada J, Sakuta H, Takahashi
M, Suzuki R, Ohkawara T, Takahashi H, Noda M: Large-scale screen and
characterization of genes with asymmetric expression patterns in the
developing chick retina. J Neurobiol in press 2.Ivanova A, Nakahira E, Kagawa T, Oba A, Wada T, Takebayashi H, Spassky N, Levine J, Zalc B, Ikenaka K: Evidence for a second wave of oligodendrogenesis in the postnatal cerebral cortex of the mouse. J Neurosci Res 73: 581-592, 2003 3.Iwasaki Y, Hosoya T, Takebayashi H, Ogawa Y, Hotta Y, Ikenaka K: The potential to induce glial differentiation is conserved between Drosophila and mammalian glial cells missing (gcm) genes. Development 130: 6027-6035, 2003 4.Fukuda S, Kondo T, Takebayashi H, Taga T: Negative regulatory effect of an oligodendrocytic bHLH factor OLIG2 on the astrocyte differentiation pathway. Cell Death Differ 11: 196-202, 2004 5.Yokoo H, Nobusawa N, Takebayashi H, Ikenaka K, Isoda K,
Kamiya M, Sasaki A, Hirato J, Nakazato Y: Anti-human Olig2 antibody
as a useful immunohistochemical marker of normal oligodendrocytes and
gliomas. Am J Pathol in press 2.Okada T, Yamada N, Tsuzuki K, Horikawa PM, Tanaka K, Ozawa S: Long-term potentiation in the hippocampal CA1 area and dentate gyrus plays different roles in spatial learning. Eur J Neurosci 17: 341-349, 2003 3.Mitamura Y, Harada T, Harada C, Ohtsuka K, Kotake S, Ohno S, Tanaka K, Takeuchi S, Wada K: NF-kB in epiretinal membranes after human diabetic retinopathy. Diabetologia 46: 699-703, 2003 4.Iwabuchi M, Ui-Tei K, Yamada Y, Matsuda Y, Sakai Y, Tanaka K, Ohki-Hamazaki H: Molecular cloning and characterzation of avian bombesin-like peptide receptors: New tools for investigating molecular basis for ligand selectivity. Br J Pharmacol 139: 555-566, 2003 5.Voutsinos-Porche B, Knott G, Tanaka K, Quairiaux C, Welker E, Bonvento G: Glial glutamate transporters and maturation of the mouse somatosensory cortex. Cereb Cortex 13: 1110-1121, 2003 6.Mitani A, Tanaka K: Functional changes of glial glutamate transporter GLT-1 during ischemia: An in vivo study in the hippocampal CA1 of normal mice and of mutant mice lacking GLT-1. J Neurosci 23: 7176-7182, 2003 7.Harada C, Harada T, Quah HMA, Maekawa F, Yoshida K, Ohno S, Wada K, Parada LF, Tanaka K: Potential role of glial cell line-derived neurotrophic factor receptors in Muller glial cells during light-induced retinal degeneration. Neuroscience 122: 229-235, 2003 8.Jin ZH, Kikuchi T, Tanaka K, Kobayashi T: Expression of GLAST in the developing mouse cochlea. Tohoku J Exp Med 200: 137-144, 2003 9.Harada T, Harada C, Wang YU, Osaka H, Amanai K, Tanaka K, Takizawa S, Setsuie R, Sakurai M, Sato Y, Noda M, Wada K: Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivo. Am J Pathol 164: 59-64, 2004 10.Huang Y, Dykes Hoberg M, Tanaka K, Rothstein JD, Bergles DE: Climbing fiber activation of EAAT4 transporters and kainite receptors in cerebellar Purkinje cells. J Neurosci 24: 103-111, 2004 11.Harada C, Harada T, Mitamura Y, Quah HMA, Ohtsuka K, Kotake S, Ohno S, Wada K, Takeuchi S, Tanaka K: Diverse NF-kB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopaty. Mol Vision 10: 31-36, 2004 12.Chen W, Mahadomrongkul V, Berger UV, Bassan M, DeSilva T, Tanaka K, Irwin N, Aoki C, Rosenberg PA: The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons. J Neurosci 24: 1136-1148, 2004 13.Maekawa F, Quah HMA, Wada E, Wada K, Tanaka K, Ohki-Hamazaki H: Leptin resistance and enhancement of feeding facilitation by melanin-concentrating hormone in mice lacking bombesin receptor subtype-3 (BRS-3). Diabetes in press 14.Maekawa F, Tsukahara S, Tanaka K, Ohki-Hamazaki H: Distributions of two chicken bonbesin receptors, bombesin receptor subtype-3.5 (chBRS-3.5) and gastrin-releasing peptide receptor (chGRP-R) mRNA's in chicken telencephalon. Neuroscience in press 15.Huang YH, Tanaka K, Rothstein JD, Bergles DE: Astrocyte
glutamate transporters regulate metabotropic glutamate receptor-mediated
excitation of hippocampal interneurons. J Neurosci in press 2.Tabata H, Nakajima K: Multipolar migration: the third mode of radial neuronal migration in the developing cerebral cortex. J Neurosci 23: 9996-10001, 2003 3.Yip YP, Capriotti C, Magdaleno S, Benhayon D, Curran T, Nakajima K, Yip JW: Components of the Reelin signaling pathway are expressed in the spinal cord. J Comp Neurol 470: 210-219, 2004 4.Hirabayashi Y, Itoh Y, Tabata H, Nakajima K, Akiyama T,
Masuyama N, Gotoh Y: The Wnt-ß-catenin pathway directs neuronal differentiation
of cortical neural precursor cells. Development in press 2.Katoh H, Negishi M: RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 424: 461-464, 2003 3.Yamaguchi Y, Katoh H, Negishi M: N-terminal short sequences of α subunits of the G12 family determine selective coupling to receptors. J Biol Chem 278: 14936-14939, 2003 4.Oinuma I, Katoh H, Harada A, Negishi M: Direct interaction
of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation
by Plexin-B1 and induces cell contraction in COS-7 cells. J Biol Chem 278: 25671-25677, 2003 2.Mutoh T, Hamada S, Senzaki K, Murata Y, Yagi T: Cadherin-related neuronal receptor 1 has cell-adhesion activity with beta1 integrin. Exp Cell Res in press 3.Sugino H, Yanase H, Hamada S, Kurokawa K, Asakawa S, Shimizu
N, Yagi T: Distinct genomic sequence of the CNR/Pcdhα genes in chicken.
Biochem Biophys Res Commun in press 2.Miyahara M, Shirasaki R, Tashiro Y, Muguruma K, Heizmann CW, Murakami F: Pathfinding and growth termination of primary trigeminal sensory afferents in the embryonic rat hindbrain. J Comp Neurol 460: 503-513, 2003 3.Hattori S, Murakami F, Song W-J: Rundown of a transient potassium current is attributable to changes in channel voltage dependence. Synapse 48: 57-65, 2003 4.Kawauchi D, Kobayashi H, Sekine-Aizawa Y, Fujita SC, Murakami F: MuSC is involved in regulating axonal fasciculation of mouse primary vesicular afferents. Eur J Neurosci 18: 2244-2252, 2003 5.Tanaka D, Nakaya Y, Yanagawa Y, Obata K, Murakami F: Multimodal tangential migration of neocortical GABAergic neurons independent of GPI-anchored proteins. Development 130: 5803-5813, 2003 6.Hattori S, Murakami F, Song W-J: Quantitative relationship between Kv4.2 mRNA and A-Type K+ current in rat striatal cholinergic interneurons during development. J Neurophysiol 90: 175-183, 2003 7.Hanamura K, Harada A, Kato-Semba R, Murakami F, Yamamoto
N: BDNF and NT-3 promote thalamocortical axon growth with distinct
substrate and temporal dependency. Eur J Neurosci in press 2.Wakamatsu Y, Osumi N, Weston JA: Expression of a novel secreted factor, Seraf indicates an early segregation of Schwann cell precursors from neural crest during avian development. Dev Biol in press |
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