津本忠治（大阪大学・大学院医学系研究科）

1.Salami M, Itami C, Tsumoto T, Kimura F: Change of conduction velocity by regional myelination yields constant latency irrespective of distance between thalamus and cortex. Proc Nat Acad Sci USA 100: 6174-6179, 2003

2.Kohara K, Kitamura A, Adachi N, Nishida M, Itami C, Nakamura S, Tsumoto T: Inhibitory, but not excitatory cortical neurons require presynaptic BDNF for dendritic development, as revealed by chimera cell culture. J Neurosci 23: 6123-6131, 2003

3.Itami C, Kimura F, Kohno T, Matsuoka M, Ichikawa M, Tsumoto T, Nakamura S: BDNF-dependent unmasking of “silent”synapses in developing mouse barrel cortex. Proc Nat Acad Sci USA 100: 13069-13074, 2003

4.Jiang B, Akaneya Y, Hata Y, Tsumoto T: Long-term depression is not induced by low frequency stimulation in rat visual cortex in vivo: A possible preventing role of endogenous BDNF. J Neurosci 23: 3761-3770, 2003

5.Yasuda H, Higashi H, Kudo Y, Inoue T, Hata Y, Mikoshiba K, Tsumoto T.: Imaging of calcineuin activated by long-term depression-inducing synaptic inputs in living neurons of rat visual cortex. Eur J Neurosci 17: 287-297, 2003

6.Ichisaka S, Katoh-Semba R, Hata Y, Ohsima M, Kameyama K, Tsumoto T: Activity-dependent changes in the protein level of brain-derived neurotrophic factor but no change in other neurotrophins in the visual cortex of young and adult ferrets. Neuroscience 117: 361-371, 2003

7.Akaneya Y, Altinbaev RS, Bayazito LT, Kinoshita S, Voronin LL, Tsumoto T: Low-frequency depression of synaptic responses recorded from rat visual cortex. Neuroscience 117: 305-320, 2003

8.Katoh-Senba R, Ichisaka S, Hata Y, Tsumoto T, Eguchi K, Miyazaki N, Matsuda M, Takeuchi IK, Kato K: NT-4 protein is localized in neuronal cells in the brain stem as well as the dorsal root ganglion of embryonic and adult rats. J Neurochem 86: 660-668, 2003

9.Palizvan MR, Sohya K, Kohara K, Maruyama A, Yasuda H, Kimura F, Tsumoto, T: Brain-derived neurotrophic factor increases inhibitory synapses, revealed in solitary neurons cultured from rat visual cortex. Neuroscience in press

渡辺雅彦（北海道大学・大学院医学研究科）

1.Sakai K, Shimizu H, Koike T, Furuya S, Watanabe M: Neutral amino acid transporter ASCT1 is preferentially expressed in L-Ser-synthetic/storing glial cells in the mouse with transient expression in developing capillaries. J Neurosci 23: 550-560, 2003

2.Kakizawa S, Yamada K, Watanabe M, Kano M: Effects of insulin-like growth factor I on climbing fiber synapse elimination during cerebellar development. Eur J Neurosci 17: 545-554, 2003

3.Fukaya M, Kato A, Lovett C, Tonegawa S, Watanabe M: Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice. Proc Natl Acad Sci USA 100: 4855-4860, 2003

4.Shibata T, Watanabe M, Ichikawa R, Ameda K, Koyanagi T: Transient neonatal expression of NR2B/2D subunit mRNAs of the N-methyl-D-aspartate receptor in the parasympathetic preganglionic neurons in the rat spinal cord. Dev Brain Res 140: 263-268, 2003

5.Somogyi P, Dalezios Y, Luján R, Roberts DB, Watanabe M, Shigemoto R: High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurones in the rat hippocampus. Eur J Neurosci 17: 2503-2520, 2003

6.Miyazaki T, Fukaya M, Shimizu H, Watanabe M: Developmental switching of vesicular glutamate transporters at parallel fiber-Purkinje cell synapses. Eur J Neurosci 17: 2563-2572, 2003

7.Sassoe-Pngnetto M, Utvik JK, Camoletto P, Watanabe M, Stephenson FA, Bredt DS, Otternen OP: Organization of postsynaptic density proteins and glutamate receptors in axodendritic and dendrodendritic synapses of the rat olfactory bulb. J Comp Neurol 463: 237-248, 2003

8.Miyata M, Kashiwadani H, Fukaya M, Hayashi T, Wu D, Suzuki T, Watanabe M, Kawakami Y: Role of thalamic phospholipase Cbeta-4 mediated by metabotropic glutamate receptor type 1 in inflammatory pain. J Neurosci 23: 8098-8108, 2003

9.Jourdi H, Iwakura Y, Narisawa-Saito M, Ibaraki K, Xiong H, Watanabe M, Hayashi Y, Takei N, Nawa H: Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Dev Biol 263: 216-230. 2003

10.Takahashi Y, Mori H, Mishina M, Watanabe M, Fujiwara T, Shimomura J, Aiba H, Miyajima T, Saito Y, Nezu A, Nishida H, Imai K, Sakaguchi N, Kondo N: Autoantibodies to NMDA receptor in patients with chronic forms of epilepsia partialis continua. Neurology 61: 891-896, 2003

11.Yamashita N, Sakai K, Furuya S, Watanabe M: Selective expression of L-serine synthetic enzyme 3PGDH in Schwann cells, perineuronal glia, and endoneurial fibroblasts along sciatic nerves and its upregulation after crush injury. Arch Histol Cytol 66: 429-436. 2003

12.Yoshida K, Furuya S, Osuka S, Mitoma J, Shinoda Y, Watanabe M, Azuma N, Tanaka H, Hashikawa T, Itohara S, Hirabayashi Y: Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality. J Biol Chem 279: 3573-3577, 2004

13.Somogyi J, Baude A, Omori Y, Shimizu H, Mestikawy SE, Fukaya M, Shigemoto R, Watanabe M, Somogyi P: GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. Eur J Neurosci 19: 552-569, 2004

14.Kinoshita N, Kimura K, Matsumoto N, Watanabe M, Fukaya M, Ide C: Mammalian septin Sept2 modulates the activity of GLAST, a glutamate transporter in astrocytes. Genes Cells 9: 1-14, 2004

15.Miyazaki M, Hashimoto K, Shin H-S, Kano M, Watanabe M: P/Q-type Ca²⁺ channel alpha-1A regulates synaptic competition on developing cerebellar Purkinje cells J Neurosci 24: 1734-1743, 2004

16.Nakashima T, Tomi M, Katayama K, Tachikawa M, Watanabe M, Terasaki T, Hosoya K: Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-retinal barrier. J Neurochem in press

17.Hama K, Aoki J, Fukaya M, Kishi Y, Sakai T, Suzuki R, Ohta H, Yamori T, Watanabe M, Chun J, Arai H: Lysophosphatidic acid and autaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J Biol Chem in press

井本敬二（岡崎国立共同研究機構・生理学研究所）

1.Mori M, Konno T, Morii T, Nagayama K, Imoto K: Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe. Biochem Biophys Res Commun 307:290-296, 2003

2.Akiba I, Seki T, Mori M, Iizuka M, Nishimura S, Sasaki S, Imoto K, Barsoumian EL: Stable expression and characterization of human PN1 and PN3 sodiumchannels. Receptors Channels 9:291-299, 2003

岡村康司（岡崎国立共同研究機構・統合バイオサイエンスセンター）

1.Izumi-Nakaseko H, Yamaguchi S, Ohtsuka Y, Ebihara T, Adachi-Akahane S, Okamura Y: DHP-insensitive L-type-like Ca channel of ascidian acquires sensitivity to DHP with single amino acid change in domain III P-region. FEBS Lett 549: 67-71, 2003

2.Nakajo K, Okamura Y: Development of transient outward currents coupled with Ca²⁺-induced Ca²⁺ release mediates oscillatory membrane potential in ascidian muscle cell. J Neurophysiol in press

尾崎美和子（理化学研究所・脳科学総合研究センター）

1.Ozaki M: Fundamental principles for brain information processing. J Soc Jpn Wem Sci 3: 6-11, 2003

2.Ozaki M, Osuka S, Osima E, Taguchi R, Hirabayashi Y: Neuregulin ErbB receptors are localized in microdomain lipid raft of cerebellar granule cells. Neuron Glia Biol in press

3.Ozaki M, Itoh K, Miyakawa Y, Kishida H, Hashikawa T: Protein processing and release of neuregulin are regulated in an activity-dependent manner. J Neurochem in press

4.Ozaki M, Itoh K, Miyakawa Y, Kishida H, Hashikawa T: Proteolytic cleavage of neuregulin is regulated by electrical activities in a frequency-dependent manner. J Biol Chem in press

駒田雅之（東京工業大学・大学院生命理工学研究科）

1.Mizuno E, Kawahata K, Kato M, Kitamura N, Komada M: STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif. Mol Biol Cell 14: 3675-3689, 2003

2.Kunzmann S, Wohlfahrt JG, Itoh S, Asao H, Komada M, Akdis CA, Blasr K, Schmidt-Weber CB: SARA and Hgs attenuate susceptibility to TGF-β1-mediated T cell suppression. FASEB J 17: 194-202, 2003

3.Mizuno E, Kawahata K, Okamoto A, Kitamura N, Komada M: Association with Hrs is required for the early endosomal localization, stability, and function of STAM. J Biochem 135: 385-396, 2004

佐藤勝重（東京医科歯科大学・大学院医歯学総合研究科）

1.Momose-Sato Y, Miyakawa N, Mochida H, Sasaki S, Sato K: Optical analysis of large-scale depolarization waves in the embryonic brain: a dual network of gap junctions and chemical synapses. J Neurophysiol 18: 600-614, 2003

2.Sato K, Momose-Sato Y: Optical detection of developmental origin of synaptic function in the embryonic chick vestibulo-cochlear nuclei. J Neurophysiol 89: 2315-3224, 2003

3.Momose-Sato Y, Mochida H, Sasaki S, Sato K: Depolarization waves in the embryonic CNS triggered by multiple sensory inputs and spontaneous activity: optical imaging with a voltage-sensitive dye. Neuroscience 116: 407-423, 2003

4.Miyakawa N, Yazawa I, Sasaki S, Momose-Sato Y, Sato K: Optical analysis of acute spontaneous epileptiform discharges in the in vivo rat cerebral cortex. NeuroImage18: 622-632, 2003

5.Sasaki S, Sato K, Shinomiya K, Momose-Sato Y: Postnatal changes in intrinsic optical responses to peripheral nerve stimulation in the in vivo rat spinal cord. NeuroImage 20: 2126-2134, 2003

6.Momose-Sato Y, Honda Y, Sasaki H, Sato K: Optical mapping of the functional organization of the rat trigeminal nucleus: Spatial and temporal dynamics of sensory information transfer during embryogenesis. J Neurosci 24: 1366-1376, 2004

7.Sato K, Miyakawa N, Momose-Sato Y: Optical survey of neural circuit formation in the embryonic chick vagal pathway. Eur J Neurosci 19: 1217-1775, 2004

宋　文杰（大阪大学・大学院工学研究科）

1.Hattori S, Murakami F, Song W-J: Rundown of a transient potassium current is attributable to change in channel voltage-dependence. Synapse 48: 57-65, 2003

2.Hattori S, Murakami F, Song W-J: Quantitative relationship between between Kv4.2 mRNA and A-type potassium current in rat striatal cholinergic interneurons during postnatal development. J Neurophysiol 90: 175-183, 2003

3.Saitoh K, Hattori S, Song W-J, Isa T, Takakusaki K: Nigral GABAergic inhibition upon cholinergic neurons in the rat pedunculopontine tegmental nucleus. Eur J Neurosci 18: 879-886, 2003

4.Inagaki S, Katura T, Kawaguchi H, Song W-J: Isolation of neural activity from respiratory and heartbeat noises for in vivo optical recordings using independent component analysis. Neurosci Lett 352: 9-12, 2003

5.Shin R-M, Masuda M, Miura M, Sano H, Shirasawa T, Song W-J, Kobayashi K, Aosaki T: Dopamine D4 receptor-induced postsynaptic inhibition of GABAergic currents in mouse globus pallidus neurons. J Neurosci 23: 11662-11672, 2003

6.Otsuka T, Abe T, Tsukagawa T, Song W-J: Conductance-based model of the voltage-dependent generation of a plateau potential in subthalamic neurons. J Neurophysiol in press

程　肇（東京大学・ヒトゲノム解析センター）

1.Kojima S, Hirose M, Tokunaga K, Sakaki Y, Tei H: Structural and functional analysis of 3' untranslated region of mouse Period1 mRNA. Biochem Biophys Res Commun 301: 1-7, 2003

2.Herzog ED, Aton SJ, Numano R, Sakaki Y, Tei H: Temporal precision in the mammalian circadian system: a reliable clock from less reliable neurons. J Biol Rhythms 19: 35-46, 2004

鍋倉淳一（岡崎国立共同研究機構・生理学研究所）

1.Moriguchi S, Mizoguchi Y, Tomimatsu Y, Hayashi Y, Kadowaki T, Kagamiishi Y, Katsube N, Yamamoto K, Inoue K, Watanabe S, Nabekura J, Nakanishi H: Potentiation of NMDA receptor-mediated synaptic responses by microglia. Mol Brain Res 119: 160-169, 2003

2.Mizoguchi Y, Nabekura J: Sustained intracellular Ca²⁺ elevation induced by a brief BDNF application in rat visual cortex neurons. Neuroreport 14: 1481-1483, 2003

3.Jong HJ, Jang IS, Nabekura J, Akaike N: Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons. J Neurophysiol 89: 1214-1222, 2003

4.Matsuo S, Jang I, Nabekura J, Akaike N: alpha2 adrenoceptor mediated presynaptic modulation of GABAergic transmission in mechanically dissociated rat ventrolateral preoptic neurons. J Neurophysiol 89:1640-1648, 2003

5.Mizoguchi Y, Kanematsu T, Hirata M, Nabekura J: A rapid increase in the total number of cell surface functional GABA_A receptors induced by brain-derived neurotrophic factor in rat visual cortex. J Biol Chem 278: 44097-44102, 2003

6.Mizoguchi Y, Ishibashi H, Nabekura J: The action of BDNF on GABA_A currents changes from potentiating to suppressing during maturation of rat hippocampal CA1 pyramidal neurons. J Physiol 548: 703-709, 2003

7.Nabekura J, Katsurabayashi S, Kakazu Y, Shibata S, Matsubara A, Jinno S, Mizoguchi Y, Sasaki A, Ishibashi H: Developmental switch from GABA to glycine release in single central synaptic terminals. Nat Neurosci 7: 17-23, 2004

8.Shibata S, Kakazu Y, Okabe A, Fukuda A, Nabekura J: Experience-dependent changes in intracellular Cl- regulation in developing auditory neurons. Neurosci Res 48: 211-220, 2004

橋本浩一（金沢大学・大学院医学系研究科）

1.Hashimoto K, Kano M: Functional differenciation of multiple climbing fiber inputs during synapse elimination in the developing cerebellum. Neuron 38: 785-796, 2003

2.Takeda Y, Akasaka K, Lee S, Kobayashi S, Kawano H, Murayama S, Takahashi N, Hashimoto K, Kano M, Asano M, Sudo K, Iwakura Y, Watanabe K: Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup. J Neurobiol 56: 252-265, 2003

3.Kitao Y, Hashimoto K, Matsuyama T, Iso H, Tamatani T, Hori O, Stern DM, Kano M, Ozawa K, Ogawa S: ORP150/HSP12A regulates Purkinje cell survival: A role for endoplasmic reticulum stress in cerebellar development. J Neurosci 24: 1486-1496, 2004

4.Miyazaki T, Hashimoto K, Shin H-S, Kano M, Watanabe M: P/Q-type Ca²⁺ channel alpha1A regulates synaptic competition on developing cerebellar Purkinje cells. J Neurosci 24: 1734-1743, 2004

林　基治（京都大学・霊長類研究所）

1.Ohira K, Hayashi M: Expression of TrkB subtypes in the adult monkey cerebellar cortex. J Chem Neuroanat 25: 175-183, 2003

2.Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M: Cell type- and region-specific expression of protein kinase C-substrate mRNAs in the cerebellum of the macaque monkey. J Comp Neurol 467: 135-149, 2003

3.Ohira K, Funatsu N, Nakamura S, Hayashi M: Expression of BDNF and TrkB receptor subtypes in the postnatal developing Purkinje cells of monkey cerebellum. Gene Expr Patt in press

4.Higo H, Oishi T, Yamashita A, Matsuda K, Hayashi M: Cell type- and region-specific expression of neurogranin mRNA in the cerebral cortex of the macaque monkey. Cereb Cortex in press

福田敦夫（浜松医科大学・医学部）

1.Farkas I, Takahashi M, Fukuda A, Yamamoto N, Akatsu H, Baranyi L, Tateyama H, Yamamoto T, Okada N, Okada H: Complement C5a receptor-mediated signalling may be involved in neurodegeneration in Alzheimer’s disease. J Immunol 170: 5764-5771, 2003

2.Isomura Y, Sugimoto M, Fujiwara-Tsukamoto Y, Yamamoto-Muraki S, Yamada J, Fukuda A: Synaptically activated Cl^– accumulation responsible for depolarizing GABAergic responses in mature hippocampal neurons. J Neurophysiol 90: 2752-2756, 2003

3.Ikeda M, Toyoda H, Yamada J, Okabe A, Sato K, Hotta Y, Fukuda A: Differential development of cation-chloride cotransporters and Cl^– homeostasis contributes to differential GABAergic actions between developing rat visual cortex and dorsal lateral geniculate nucleus. Brain Res 984: 149-159, 2003

4.Okabe A, Yokokura M, Toyoda H, Shimizu-Okabe C, Ohno K, Sato K, Fukuda A: Changes in chloride homeostasis-regulating gene expressions in the rat hippocampus following amygdala kindling. Brain Res 990: 221-226, 2003

5.Takeuchi K, Fukuda A, Kanayama, N: Effect of urinary trypsin inhibitor on potassium currents: fetus modulates membrane excitability by production of UTI. Acta Obstet Gynecol Scand 83: 6-11, 2004

6.Okabe A, Kilb W, Shimizu-Okabe C, Hanganu IL, Fukuda A, Luhmann HJ: Homogenous glycine receptor expression in cortical plate neurons and Cajal-Retzius cells of neonatal rat cerebral cortex. Neuroscience 123: 715-724, 2004

7.Nakanishi K, Watanabe K, Kawabata M, Fukuda A, Oohira A: Altered synaptic activities in cultures of neocortical neurons from prenatally X-irradiated rats. Neurosci Lett 355: 61-64, 2004

8.Shibata S, Kakazu Y, Okabe A, Fukuda A, Nabekura J: Experience-dependent changes in intracellular Cl^– regulation in developing auditory neurons. Neurosci Res 48: 211-220, 2004

9.Inoue K, Ueno S, Fukuda A: Interaction of neuron-specific K⁺-Cl^– cotransporter, KCC2, with brain-type creatine kinase. FEBS Lett in press

籾山俊彦（岡崎国立共同研究機構・生理学研究所）

1.Momiyama T: Parallel decrease in omega-conotoxin-sensitive transmission and dopamine-induced inhibition at the striatal synapse of developing rats. J Physiol 546: 483-490, 2003

2.Kaifu T, Nakahara J, Inui M, Mishima K, Momiyama T, Kaji M, Sugahara A, Koito H, Ujike-Asai A, Nakamura A, Kanazawa K, Tan-Takeuchi K, Iwasaki K, Yokoyama WM, Kudo A, Fujiwara M, Asou H, Takai T: Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice. J Clin Invest 111: 323-332, 2003

森山芳則（岡山大学・大学院自然科学研究科）

1.Morimoto R, Hayashi M, Yatsushiro S, Otsuka M, Yamamoto A, Moriyama Y: Co-expression of vesicular glutamate transporters (VGLUT1 and VGLUT2) and their association with synaptic-like microvesicles in rat pinealocytes. J Neurochem 84: 382-391, 2003

2.Hayashi M, Yamada H, Uehara S, Morimoto R, Muroyama A, Takeda J, Yamamoto A, Moriyama Y: Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers a glutamatergic signal transmisson in islets of Langerhans. J Biol Chem 278: 1966-1974, 2003

3.Kinuta M, Kinuta K, Yamada H, Abe T, Yoshida Y, Araki K, Li SA, Otsuka A, Nakanishi A, Moriyama Y, Takei K: Formation of S-(2-carboxy-1-(1H-imidazol-4-yl)ethyl)glutathione, a new metabolite of L-histidine, from cis -urocanic acid and glutathione by the action of glutathione S-transferase. Electrophoresis 24: 3212-3218, 2003

4.Hayashi M, Otsuka M, Morimoto R, Muroyama A, Uehara S, Yamamoto A, Moriyama Y: Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in αTC6 cells, mouse clonal α cells, and α cells of islets of Langerhans. Diabetes 52: 2066-2074, 2003

5.Taraschi TF, O’Donnell M, Martinez S, Schneider T, Trelka D, Tilley L, Moriyama Y: Generation of an erythrocyte protein secretory system by Plasmodium falciparum Malaria parasites. Blood 102: 3420-3426, 2003

6.Hayashi M, Morimoto R, Yamamoto A, Moriyama Y: Expression and localization of vesicular glutamate transporters in pancreatic islets, upper gastrointestinal tract, and testis. J Histochem Cytochem 51: 1375-1390, 2003

7.Wang H, Ichihara G, Ito H, Kato K, Kitoh J, Yamada T, Yu X, Tsuboi S, Moriyama Y, Takeuchi Y: Dose-dependent biochemical changes in rat central nervous system after 12-week exposure to 1-bromopropane. Neurotoxicology 24: 199-206, 2003

8.Moriyama Y, Hayashi M: Glutamatergic signaling in islet of Langerhans: A thread entangled. Trends Pharmacol Sci 24: 511-517, 2003

9.Anno T, Uehara S, Katagiri H, Ohta Y, Ueda K, Mizuguchi H, Moriyama Y, Oka Y, Tanizawa Y: Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation. Am J Physiol Endocrinol Metab 286: E280-E285, 2004

10.Moriyama Y, Yamamoto A: Glutamatergic chemical transmission: Look! Here, there, and anywhere. J Biochem 135: 155-163, 2004

11.Uehara S, Muroyama A, Echigo N, Morimoto R, Otsuka M, Yatsushiro S, Moriyama Y: Metabotropic glutamate receptor type 4 is involved in auto-inhibitory cascade for glucagon secretion by α cells of islet of Langerhans. Diabetes 53, 2004, in press